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Panoramic Radiography Measurements Not Correlated with BMD Results in End-stage Chronic Kidney Disease Patients Ni'ami, Muhamad Aufa; Ferriastuti, Widiana; Rahardjo, Paulus
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14182

Abstract

Chronic kidney disease (CKD) is a disorder of the kidney defined by a glomerular filtration rate of less than 60 ml/min/1.73 m2 for a minimum of three months, progressive and irreversible. One complication is chronic kidney disease-metabolic bone disorders (CKD-MBD), which can cause osteoporosis. This is diagnosed using bone mineral densitometry-dual energy absorptiometry (BMD-DXA) and panoramic radiographs, which can also detect thinning of the mandibular cortex in patients with CKD. This study aims to determine the correlation between osteoporosis images on panoramic photos with the results of lumbar and hip areal T-scores in chronic kidney disease (CKD). This research is an observational study with a prospective approach and cross-sectional design. The subjects of this study were 52 patients with chronic kidney disease (CKD). Undergoing hemodyalize procedure (HD) at Dr. Soetomo General Hospital for February–March 2024. Data was collected by taking the results of the panoramic photo examination and BMD-DXA to see the results of the T-score in each patient—data analysis using the Spearman test on SPSS software. Which resulted in the p-values for the panoramic mandibular index (PMI), mandibular cortical width (MCW), and mandibular cortical index (MCI) with a lumbar T-score range of 0.093 to 0.676 and the PMI, MCW, and MCI with left-right hip T-score, the p-values ranged from 0.318 to 0.970 (all p-values >0.05). It can be concluded that there is no correlation between the results of the T-score for the lumbar and hip regions and the measurements of PMI, MCW, and MCI. Therefore, employing these three measurements as a standard for osteoporosis screening using panoramic x-rays is not feasible.
Panoramic Radiography Measurements Not Correlated with BMD Results in End-stage Chronic Kidney Disease Patients Ni'ami, Muhamad Aufa; Ferriastuti, Widiana; Rahardjo, Paulus
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14140

Abstract

Chronic kidney disease (CKD) is a disorder of the kidney defined by a glomerular filtration rate of less than 60 ml/min/1.73 m2 for a minimum of three months, progressive and irreversible. One complication is chronic kidney disease-metabolic bone disorders (CKD-MBD), which can cause osteoporosis. This is diagnosed using bone mineral densitometry-dual energy absorptiometry (BMD-DXA) and panoramic radiographs, which can also detect thinning of the mandibular cortex in patients with CKD. This study aims to determine the correlation between osteoporosis images on panoramic photos with the results of lumbar and hip areal T-scores in chronic kidney disease (CKD). This research is an observational study with a prospective approach and cross-sectional design. The subjects of this study were 52 patients with chronic kidney disease (CKD). Undergoing hemodyalize procedure (HD) at Dr. Soetomo General Hospital for February–March 2024. Data was collected by taking the results of the panoramic photo examination and BMD-DXA to see the results of the T-score in each patient—data analysis using the Spearman test on SPSS software. Which resulted in the p-values for the panoramic mandibular index (PMI), mandibular cortical width (MCW), and mandibular cortical index (MCI) with a lumbar T-score range of 0.093 to 0.676 and the PMI, MCW, and MCI with left-right hip T-score, the p-values ranged from 0.318 to 0.970 (all p-values >0.05). It can be concluded that there is no correlation between the results of the T-score for the lumbar and hip regions and the measurements of PMI, MCW, and MCI. Therefore, employing these three measurements as a standard for osteoporosis screening using panoramic x-rays is not feasible.
Effect of Umbilical Cord-derived Mesenchymal Stem Cell Secretome on Corpus Cavernosum Elastography Results in Patients with Severe Erectile Dysfunction Non-responsive to Sildenafil Pratama, Andi Ahmad Thoriq; Rahardjo, Paulus; Atmaja, M Hidayat Surya; Supardi, Petrus; Margiana, Ria
Global Medical & Health Communication (GMHC) Vol 13, No 1 (2025)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v13i1.14144

Abstract

Erectile dysfunction is one of the most common male sexual dysfunctions, defined as the inability to get or maintain an erection, and its prevalence is increasing over time. The current treatment, using a phosphodiesterase-5 inhibitor like sildenafil, only offers a temporary solution. Secretome, a bioactive substance derived from mesenchymal stem cells from the umbilical cord, has shown remarkable regenerative capabilities. This study aims to explore the potential of administering umbilical cord-derived mesenchymal stem cell secretome to patients with severe erectile dysfunction and evaluate its impact on the stiffness of the corpus cavernosum using elastography in the flaccid phase. This study employed a pre-experimental design with a pre-post test. It involved seven patients who came to Dr. Soetomo Hospital with severe erectile dysfunction that was unresponsive to sildenafil. Elastography evaluation, including strain and shear wave elastography, was performed before and one month after secretome injection, which was carried out from March to April 2024. Data were analyzed using the paired sample t-test when the data distribution was normal and the Wilcoxon test when the data distribution was not normal. There were statistically significant changes (p<0.05) in all patients who underwent strain and shear wave elastography of the corpus cavernosum before and one month after secretome administration, indicating an improvement in stiffness. In conclusion, intracavernosal administration of umbilical cord-derived mesenchymal stem cell secretome has demonstrated promising results in treating severe erectile dysfunction non-responsive to sildenafil therapy. These results include improved penile tissue in the corpus cavernosum, as evidenced by decreased stiffness on elastography.
KARAKTERISTIK PENDERITA OMSK TIPE AMAN DENGAN RINITIS ALERGI DI IRJ RSUD DR. SOETOMO SURABAYA PERIODE JULI — DESEMBER 2017 rifdah, salsabila nabilah; artono, artono; rahardjo, paulus
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 9, No 1 (2021): EDITION MARCH 2021
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v9i1.1381

Abstract

Chronic suppurative otitis media (CSOM) is a chronic inflammatory process of the middle ear mucosa and mastoid cavity accompanied by tympanic membrane perforation and a history of discharge from the ear canal for more than two months, whether continuous or intermittent. The presence of allergies is thought to play an important role in the occurrence of safe type CSOM. Until now there have been no studies on the characteristics of safe type CSOM patients with allergic rhinitis at the IRJ Hospital Dr. Soetomo Surabaya in 2017. Based on this, it is necessary to conduct research to find out information on the characteristics of patients with safe type CSOM with allergic rhinitis at the IRJ Hospital Dr. Soetomo Surabaya. This study was a retrospective descriptive observational study on secondary data in the form of medical records in patients with safe type CSOM with allergic rhinitis who were treated at the RSUD Dr. Soetomo Surabaya. The results showed that the highest sex distribution was women (75%), the most age group was the age range of 21-30 years (30.56%), the most regional origin was Surabaya (58.33%), the highest employment status was not working (50%), most patients had a history of allergies (86.11%), the most family history of allergic patients was eczema (41.67%), and most allergens were house dust mites (77.77%).