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All Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Cermin Dunia Kedokteran
Mutiara, Rizka
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Health Professions Medicine & Pharmacology

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The Effectiveness of a High-Protein Liquid Dietary Supplementation in Improving Nutritional Status of Malnourished Patients in Hospital Care: a Preliminary Study Simadibrata, Marcellus; Abdullah, Murdani; Witjaksono, Fiastuti; Muzellina, Virly Nanda; Utari, Amanda Pitarini; Wulandari, Yohannessa; Wijayanti, Ari; Mustikarani, Dewi; Haloho, Raja Mangatur; Rachman, Aditya; Simadibrata, Daniel Martin; Mutiara, Rizka; Renaldi, Kaka
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 23, No 1 (2022): VOLUME 23, NUMBER 1, April 2022
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (671.108 KB) | DOI: 10.24871/231202243-51

Abstract

Background: Malnutrition is a very common problem in hospitalized patients. Based on studies conducted in various countries, the prevalence of hospital malnutrition ranges from 20-45%. Hospital malnutrition can occur as a result of insufficient nutrient intake, impaired absorption of nutrients in the gastrointestinal (GI) tract, loss of nutrients due to disease, or increased metabolic requirement during illness. Nutrition is the basis for the healing process as it requires good nutrients through various enzymatic reactions. Some studies have shown that hospital malnutrition increases morbidity, mortality, prolongs the duration of hospitalization, and delays recovery. To improve nutritional status, a high-protein diet can be given. Liquid diet is one of the alternative forms of nutrition because it is easier to swallow.Method: This study was a double-blind randomized controlled trial conducted to assess the effectiveness of high protein liquid dietary supplementation in malnourished hospitalized patients. The patients were assessed for their nutritional status based on ESPEN 2015 criteria. Patients who experienced malnutrition will be divided into 2 groups, namely the control group which was given normal protein liquid diet, while the intervention group was given high protein liquid diet supplementation as much as 2 bottles (200 mL) per day for 7-10 days. Furthermore, the nutritional status of the patient was assessed.Results: By administering high-protein liquid diet supplementation, there was a tendency to increase the strength of the right handgrip in 3 subjects (50%), the tendency to increase body mass index (BMI) in 3 subjects (50%), Subjective Global Assessment (SGA) score improved in 2 subjects with mild/moderate malnutrition (33.3%) and 1 subject with normal nutrition (16.7%), and the tendency to increase the fat-free mass in 3 subjects (50%).Conclusion: The administration of high protein liquid dietary supplementation tended to increase the strength of the right handgrip, BMI, SGA score, and body fat-free mass index.
Onikomikosis yang Disebabkan oleh Kodamaea ohmeri pada Seorang Pasien dengan Virus Imunodefisiensi Manusia (HIV) – Laporan Kasus: Laporan Kasus Nadliroh, Siti; Wahid, Mardiastuti; Sjatha, Fithriyah; Haliman, Cliff Clarence; Widaty, Sandra; Mutiara, Rizka; Pratama, Aditya Indra; Asri, Rizkia Chairani; Adawiyah, Robiatul; Kusumaningrum, Ardiana
Cermin Dunia Kedokteran Vol 53 No 07 (2026): Juli 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i07.1895

Abstract

Introduction: Onychomycosis is a fungal nail infection usually caused by dermatophytes. Kodamaea ohmeri is a rare fungus that has been reported as a pathogen capable of causing onychomycosis and systemic infections. This yeast-like fungus is often misidentified as Candida sp. A complete identification is required for accurate results. Case: A 40-year-old male with HIV presented with yellow and brittle fingernails for 2 months. KOH examination of nail scrapings was performed, followed by fungal culture. The isolate was identified in parallel using the Integral System Yeast Plus, Vitek-2, MALDI-TOF (Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry), and sequencing, and the result was Kodamaea ohmeri. The patient received oral itraconazole and topical ketoconazole. Discussion: Onychomycosis in HIV patients is caused by low immunity, high viral load, and low CD4 values. In this case, K. ohmeri was successfully identified using Vitek-2, MALDI-TOF, and ITS (Internal Transcribed Spacer) area sequencing, while the Integral System Yeast Plus misidentified the isolate as Candida tropicalis. There was clinical improvement in the nail after treatment. Conclusion: Onychomycosis in HIV patients can be caused by Kodamaea ohmeri. Identification can be done with Vitek-2 and MALDI-TOF.
Co-Authors Aditya Rachman, Aditya Amanda Pitarini Utari Ardiana Kusumaningrum Ari Wijayanti Asri, Rizkia Chairani Fiastuti Witjaksono Haliman, Cliff Clarence Haloho, Raja Mangatur Kaka Renaldi Marcellus Simadibrata Murdani Abdullah Mustikarani, Dewi Muzellina, Virly Nanda Nadliroh, Siti Pratama, Aditya Indra Robiatul Adawiyah Sandra Widaty Simadibrata, Daniel Martin SJATHA, FITHRIYAH Wahid, Mardiastuti Wulandari, Yohannessa