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Journal : Jaringan Laboratorium Medis

Hubungan Kadar Kalium dan Kadar Ureum Terhadap Jenis Obat Baru pada Pasien Tuberkulosis Resistan Obat (TB RO) Anggita, Sasha Marwah; Qomariyah, Nurul; Kahar, Fitriani
Jaringan Laboratorium Medis Vol 6, No 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.11388

Abstract

The use of new types of drugs in RO TB patients will cause disturbances in the body's electrolytes, especially potassium levels, as well as disturbances in urea levels caused by the excretion of urea that is retained in the body. Continuous increases in urea in the body result in the kidneys not being able to work optimally. The aim of this study was to determine the relationship between potassium levels and urea levels on new types of drugs in RO TB patients. The research method used is analytical observational with a cross sectional approach. This research was conducted on 16 February – 16 March 2023 with research subjects being RO TB patients who received treatment with a new type of drug at the Lung Hospital dr. Ario Wirawan Salatiga as many as 21 respondents using a sampling technique that is the total population. Potassium levels were measured using the ISE (Ion Selective Electrode) method and urea levels used the enzymatic UV test method. The data was then processed using the Shapiro-Wilk normality test, then continued with prerequisite tests (crosstab test and homogeneity test) then continued with hypothesis testing, because my data scale was ratio and nominal, the alternative test used was the Chi-Square Test. The equipment test results obtained a homogeneity test with a P value of 0.698 and 0.610 (0.05), meaning the data was homogeneous. The test results for the relationship between potassium and urea levels on new types of drugs for RO TB patients were Chi-Square hypothesis test results with a P value of 0.152 and 0.384 ( 0.05) means there is no relationship between potassium levels and urea levels on new types of drugs in RO TB patients. The results show that the TB drugs bedaquiline and delamanid do not cause kidney function disorders so that RO TB patients can consume these TB drugs regularly.
Identifikasi Glukosa Urin dan Keton Urin pada Pasien Tuberkulosis Paru yang Mendapat Terapi Obat Anti Tuberkulosis (OAT) Di Puskesmas Tlogosari Wetan Hafidsya, Pradiana Syahwa; Kahar, Fitriani
Jaringan Laboratorium Medis Vol 6, No 2 (2024): November 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i2.12199

Abstract

Tuberculosis is a contagious infection caused by Mycobacterium tuberculosis. Anti-Tuberculosis Drug Therapy (OAT) given also has side effects, one of which is nephrotoxic. Laboratory examination of urine glucose identification can indicate if there is damage to the kidney glomerulus in the filtration process. The purpose of this study was to identify urine glucose and urine ketones in non-DM pulmonary TB patients with OAT treatment at the Tlogosari Wetan Health Center. This type of research is descriptive observational with a cross-sectional approach. The population was all TB patients who underwent examination at the Tlogosari Wetan Health Center. The research sample was a random urine sample from non-DM pulmonary TB patients. The examination method used was a dipstick using a reagent strip test. The results showed that out of a total of 30 non-DM pulmonary TB patients with OAT therapy (100%). A total of 6 (20%) patients were identified with urine glucose, with details of  intensive phase treatment 2 (7%) patients with trace urine glucose (±), while in the continuation phase 2 (7%) patients were identified with trace urine glucose (±) and 2 (7%) patients with low urine glucose (+1). The majority of positive urine glucose results were experienced by males with an elderly age range (46-65 years) of 4 patients (14%). The results of urine ketone identification showed that 2 (6.6%) patients were identified with urine ketones, namely trace (±) in intensive phase treatment, while 15 patients in the continuation phase had all negative urine ketones. The majority of positive urine ketone results were experienced by males with an adult age range (26-45 years) of 2 patients (14%). The conclusion of 30 non-DM pulmonary TB patients with OAT therapy who met the inclusion criteria, there were 6 (20%) patients identified with urine glucose and 2 (6.6%) patients identified with urine ketones. The impact of this study is expected for non-DM pulmonary TB patients to take OAT and have regular medical check-up.
Hubungan Pengetahuan dengan Perilaku Ibu Hamil Usia Reproduksi Sehat dengan Pemeriksaan Triple Elliminatiom Skrining (HIV, Sifilis, dan Hepatitis B) Kahar, Fitriani
Jaringan Laboratorium Medis Vol 7, No 2 (2025): November 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v7i2.12971

Abstract

Pregnant women are one of the populations at risk of contracting Sexually Transmitted Infections (STIs) such as HIV, Syphilis, and Hepatitis B. The prevalence of HIV/AIDS transmission from mother to child is 20-50% where 5-10% occurs during pregnancy. Syphilis transmission is 69-80% and Hepatitis B transmission is more than 90% with the potential for transmission during pregnancy and childbirth being very high. Based on the Regulation of the Minister of Health of the Republic of Indonesia, regulation No. 52 of 2017 concerning the Elimination Program for Transmission of Human Immunodeficiency Virus, Syphilis, and Hepatitis B from Mother to Child or often called "Triple Elimination" aims to stop transmission from mother to child with laboratory examinations on pregnant women at least once during pregnancy. The purpose of this study was to determine the relationship between knowledge and behavior of healthy reproductive age pregnant women in the first trimester at the Lebdosari Health Center. In general, this research method is qualitative with an analytical observational approach and cross-sectional design, namely researchers come and analyze the problem directly. Data collection is carried out at once within a certain time. The population is pregnant women in the first trimester at the Lebdosari Health Center, with a sample size of 49 people selected based on the Purposive Sampling technique. Data analysis was carried out descriptively and then continued with a bivariate test with the Kendal Tau test because the data was not normally distributed. The results of the study showed that the results of the bivariate test with the Kendal Tau test showed that there was no relationship between knowledge and behavior because the significance value p = 0.888 0.05 with a positive correlation coefficient value (0.19) which means that there is a positive relationship between knowledge and behavior even though the relationship is weak because the value is less than 1, so that if knowledge increases, behavior will be better. It is recommended that pregnant women are advised to always maintain personal hygiene and implement a clean and healthy lifestyle to prevent infectious diseases. 
Identifikasi Formalin pada Jajanan Siomay Kahar, Fitriani; Rondonuwu, Ferawati
Jaringan Laboratorium Medis Vol. 1 No. 2 (2019): November 2019
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v1i2.5450

Abstract

Formalin is a colorless solution and smells very strong, usually used as a preservative of dead bodies. Provision of formalin preservatives is prohibited on food, even food containing formaldehyde if consumed continuously will cause symptoms of poisoning, cancer (liver cancer) which is caused indirectly. The purpose of research on identifying formaldehyde in Siomay qualitatively is to determine whether there is formaldehyde in Siomay taken in Tamamaung Village. From the identification results, 4 out of 5 (80%) samples do not contain formalin preservatives, the benefits of research to protect the consumer community, especially Siomay fans to stay safe in consuming Siomay traded in Tamamaung Urban Village prove that there is awareness of traders in producing food especially Siomay is much favored by the community. So that the government or community leaders provide information to traders and entrepreneurs and consumers, especially the general public in Kelurahan Tamamaung about the dangers of using formalin preservatives, so that they do not use formalin as a food preservative.
Identifikasi Telur Cacing Nematoda Usus Pada Feses Anak Usia 5-10 Tahun Kahar, Fitriani; Efendi, Quirinus; Hadipranoto, Ichsan
Jaringan Laboratorium Medis Vol. 2 No. 1 (2020): May 2020
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v2i1.5872

Abstract

Humans are the host of several intestinal nematodes, most of which can cause public health problems. Among intestinal nematodes there are species that are transmitted through soil or called "soil transmitted helmith" can occur in species Ascaris lumbricoides, Ancylostoma duodenale, Trichuris trichiura. These nematodes mostly infect children aged 5-10 years. The purpose of this study was to determine the presence of intestinal nematodes in the stools of children aged 5-10 years who live around Jalan Abdul Kadir Makassar City, and this study was conducted in the D-3 laboratory of Health Analysts at the University of Eastern Indonesia Makassar with the sedimentation method. The research conducted was a laboratory observation. From examination data on 20 faecal samples of children aged 5-10 years, 7 positive samples (35%) were found, namely Ascaris lumbricoides and 1 positive sample (5%) Trichuris trichiura. From the results of the above research it is suggested to children to maintain hygienic and environmental sanitation. It is recommended to further researchers to examine Ascaris lumbricoides worms and trichuris tricura quantitative methods to measure the amount of intestinal worms infection.
Identifikasi Paparan Pediculus Humanus Capitis pada Anak Asuh di Panti Asuhan Putri, Rianita; Kahar, Fitriani; Triyono, Damas
Jaringan Laboratorium Medis Vol. 2 No. 2 (2020): November 2020
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v2i2.7060

Abstract

Pediculus humanus capitis is a parasite known as head lice. This parasite causes itching that interferes with concentration, as well as irritation of the scalp. One of the factors for the spread of this parasite is personal hygiene that is low and quickly spreads in a crowded living environment. The purpose of this study was to describe the exposure to Pediculus humanus capitis in foster children at the An-Nahl Orphanage, Sragen Regency. This research method is descriptive research through cross sectional approach. The results of this study showed that 12 foster children (86%) in An-Nahl Orphanage, Sragen Regency had Pediculus humanus capitis and 2 foster children (14%) did not find Pediculus humanus capitis. Foster children at the An-Nahl Orphanage who have good personal hygiene category, 2 foster children (14%) are negatively exposed to Pediculus humanus capitis, sufficient category is 4 foster children (29%) are positively exposed to Pediculus humanus capitis, bad personal hygiene category is 8 foster children (57%) were positively exposed to Pediculus humanus capitis. The conclusion of the study was Pediculus humanus capitis was found in foster children at An-Nahl Orphanage, Sragen Regency, as many as 57% of all foster children had poor personal hygiene
Gambaran Kepositifan Basil Tahan Asam Pasien Diagnosis Klinis Tuberculosis Paru di Balai Kesehatan Masyarakat Semarang Kahar, Fitriani; Novitasari, Putri Anggraeni; Irnawati, Irnawati
Jaringan Laboratorium Medis Vol. 4 No. 2 (2022): November 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i2.8552

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Until now, tuberculosis is still a public health problem in the world. Tuberculosis is a dangerous infectious disease, the healing process also takes a long time. Acid-fast bacilli examination is an examination to determine the presence or absence of Mycobacterium tuberculosis bacteria. The factors that influence Tuberculosis patients are age, gender, education and occupation. The purpose is to knowing the description of AFB positivity in patients with clinical diagnosis of pulmonary tuberculosis at Balkesmas Semarang in 2020. This research was an observational study with descriptive research criteria through a retrospective approach. Results from 656 patients with clinical diagnosis of tuberculosis who underwent acid-fast bacilli examination, 220 patients (33.5%) were found positive and acid-fast bacilli were negative (64.5%). The results of the examination of acid-fast bacilli were positive with a scanty positivity degree of 3 patients (1.4%), acid-fast bacilli (+1) were 71 patients (32.3%), (+2) were 83 patients (37.7%), (+3) as many as 63 patients (28.6%). Based on the category of age 0-14 years as many as 1 patient (0.5%), 15-34 years as many as 78 patients (35.5%), 35-54 years as many as 96 patients (43.6%), 55-74 years as many as 44 patients (20%), >75 years as many as 1 patient (0.5%). Based on gender, there were 123 patients (56%) male and 97 female patients (44%). Conclusion the results of the examination of acid-fast bacilli were positive with a scanty positivity rate of 3 patients (1.4%), acid-fast bacilli (+1) 71 patients (32.3%), (+2) 83 patients (37.7%), (+3) 63 patients (28.5%). Based on gender with positive acid-fast bacilli, there were 123 male patients (56%) while female 97 patients (44%). Age with the most positive acid-fast bacilli results in the range 0–14 years 1 patient (0.5%), 15–34 years 78 patients (35.5%), 35-54 years 96 patients (43.6%), 55 –74 years.
Perbandingan Hasil Pemeriksaan Protein Urine Metode Carik Celup, Asam Asetat 6%, dan Asam Sulfosalisilat 20% Menggunakan Aturan Westgard Permata Sari, Cecilia Febiyono; Kahar, Fitriani; Irnawati, Irnawati; Yusuf, Muhammad; Salam, Abdul; Wadood, Abdul
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9784

Abstract

Proteinuria is caused by kidney damage. Qualitative examination of urine protein can be carried out using the dip strip method, 6% acetic acid and 20% sulfosalicylic acid. The aim of this research is to determine the accuracy and precision of urine protein examination using the dip strip method, 6% acetic acid and 20% sulfosalicylic acid. The research was experimental with repeated measurements of levels carried out visually and gave positive results of 1, 2, 3 and 4. The research was carried out in January 2022 using a research sample of 20 proteinuria positive patients at RSJD Dr. Amino Gondohutomo. The results of this research are that all methods meet the 12S rules where there is 1 control that is more than ± 2SD (still in the ± 3SD area), categorized as a warning/warning of method malfunction (needs more careful analysis). The best method is dip strip because it has the lowest Coefficient of Variation (KV) value, namely 0.497%. The method can still be used for patient care. The coefficient of variation obtained was dye liquid 0.497%, 6% acetic acid 0.654%, and 20% sulfosalicylic acid 0.630%. The smaller the KV value (%) the more thorough the system/method. The conclusion that can be drawn from this research is that the dip strip is a method that has the best accuracy and precision compared to the 6% acetic acid and 20% sulfosalicylic acid methods because it has the smallest coefficient of variation (KV%) value, namely 0.497% and meets the 12S rules. Researchers recommend always ensuring that the research location has the required samples with adequate volume, urine protein examination can be carried out using the dip strip method, researchers can then carry out urine protein examination regarding the sensitivity and specificity of the three qualitative methods
Hubungan Kadar Kalium dan Kadar Ureum Terhadap Jenis Obat Baru pada Pasien Tuberkulosis Resistan Obat (TB RO) Anggita, Sasha Marwah; Qomariyah, Nurul; Kahar, Fitriani
Jaringan Laboratorium Medis Vol. 6 No. 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.11388

Abstract

The use of new types of drugs in RO TB patients will cause disturbances in the body's electrolytes, especially potassium levels, as well as disturbances in urea levels caused by the excretion of urea that is retained in the body. Continuous increases in urea in the body result in the kidneys not being able to work optimally. The aim of this study was to determine the relationship between potassium levels and urea levels on new types of drugs in RO TB patients. The research method used is analytical observational with a cross sectional approach. This research was conducted on 16 February – 16 March 2023 with research subjects being RO TB patients who received treatment with a new type of drug at the Lung Hospital dr. Ario Wirawan Salatiga as many as 21 respondents using a sampling technique that is the total population. Potassium levels were measured using the ISE (Ion Selective Electrode) method and urea levels used the enzymatic UV test method. The data was then processed using the Shapiro-Wilk normality test, then continued with prerequisite tests (crosstab test and homogeneity test) then continued with hypothesis testing, because my data scale was ratio and nominal, the alternative test used was the Chi-Square Test. The equipment test results obtained a homogeneity test with a P value of 0.698 and 0.610 (>0.05), meaning the data was homogeneous. The test results for the relationship between potassium and urea levels on new types of drugs for RO TB patients were Chi-Square hypothesis test results with a P value of 0.152 and 0.384 (> 0.05) means there is no relationship between potassium levels and urea levels on new types of drugs in RO TB patients. The results show that the TB drugs bedaquiline and delamanid do not cause kidney function disorders so that RO TB patients can consume these TB drugs regularly.
Identifikasi Glukosa Urin dan Keton Urin pada Pasien Tuberkulosis Paru yang Mendapat Terapi Obat Anti Tuberkulosis (OAT) Di Puskesmas Tlogosari Wetan Hafidsya, Pradiana Syahwa; Kahar, Fitriani
Jaringan Laboratorium Medis Vol. 6 No. 2 (2024): November 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i2.12199

Abstract

Tuberculosis is a contagious infection caused by Mycobacterium tuberculosis. Anti-Tuberculosis Drug Therapy (OAT) given also has side effects, one of which is nephrotoxic. Laboratory examination of urine glucose identification can indicate if there is damage to the kidney glomerulus in the filtration process. The purpose of this study was to identify urine glucose and urine ketones in non-DM pulmonary TB patients with OAT treatment at the Tlogosari Wetan Health Center. This type of research is descriptive observational with a cross-sectional approach. The population was all TB patients who underwent examination at the Tlogosari Wetan Health Center. The research sample was a random urine sample from non-DM pulmonary TB patients. The examination method used was a dipstick using a reagent strip test. The results showed that out of a total of 30 non-DM pulmonary TB patients with OAT therapy (100%). A total of 6 (20%) patients were identified with urine glucose, with details of  intensive phase treatment 2 (7%) patients with trace urine glucose (±), while in the continuation phase 2 (7%) patients were identified with trace urine glucose (±) and 2 (7%) patients with low urine glucose (+1). The majority of positive urine glucose results were experienced by males with an elderly age range (46-65 years) of 4 patients (14%). The results of urine ketone identification showed that 2 (6.6%) patients were identified with urine ketones, namely trace (±) in intensive phase treatment, while 15 patients in the continuation phase had all negative urine ketones. The majority of positive urine ketone results were experienced by males with an adult age range (26-45 years) of 2 patients (14%). The conclusion of 30 non-DM pulmonary TB patients with OAT therapy who met the inclusion criteria, there were 6 (20%) patients identified with urine glucose and 2 (6.6%) patients identified with urine ketones. The impact of this study is expected for non-DM pulmonary TB patients to take OAT and have regular medical check-up.