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All Journal DIDAKTIKA TAUHIDI: JURNAL PENDIDIKAN GURU SEKOLAH DASAR Pena : Jurnal Ilmu Pengetahuan dan Teknologi Jurnal EduHealth
Prasetyo, Fajar
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Economics, Econometrics & Finance Education Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences Veterinary Other

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Journal : Jurnal EduHealth

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The Dangerous Effects of Tramadol Abuse: Literature Review Prasetyo, Fajar; Indah Laily Hilmi
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

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Abstract

Drug abuse is an act of using one or a combination of drugs in relatively high doses with the aim not for medication but to achieve a pleasure without regard to other aspects. Drug abuse can be motivated by several factors such as a weak personality, a high sense of curiosity, peer invitations, social problems and pressures, and the ease with which drugs can be obtained at low prices. One of the drugs that is often abused is tramadol. This is because tramadol can provide a euphoric effect. Without realizing it, tramadol abuse actually causes other, more dangerous effects. Therefore, writing this review article aims to provide an overview of other effects resulting from the abuse of tramadol drugs. The writing of this article review uses a systematic review method in which data is taken from national and international scientific articles or journals with a limitation of publication in the last 10 years. Articles obtained from searches using Google Scholar, PubMed, and Science Direct. From the results of the review, it is known that the misuse of tramadol drugs can be fatal because it can cause vomiting, seizures, sedation, and even death. Not only that, tramadol in high doses also affects fertility factors such as sperm defects and erectile dysfunction. Special attention is needed for cases of tramadol abuse because most of these activities are carried out by teenagers.
Article Review: Analysis Of Artificial Sweetness In Food And Beverages: English Zakiyah, Wildani; Nurul Sa'adah, Cantika; Prasetyo, Fajar; Febiola Lubis, Christina; Lina Nurfadhila; Marsah Rahmawati Utami
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

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Abstract

Artificial sweeteners are substances added to food and beverages with the aim of giving a sweet taste, having no nutritional value. The types of artificial sweeteners allowed by the Minister of Health are Cyclamate, Saccharin, Aspartame and Sorbitol. The method used in this paper is a literature review study. The total journals used in this article review are 14 journals. In several studies, the levels of artificial sweeteners contained in related foods are still within the limits permitted by the government, but in some studies there are still foods whose levels of artificial sweeteners exceed the permitted limits.
Standardization of Anthocyanin Compounds in Plants in Indonesia: Literature Review Agustin, Annastya Eka; Mierza , Vriezka; Annisa, Bunga Nur; Sa’adah, Cantika Nurul; Prasetyo, Fajar; Lubis, Christina Febiola
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.134 KB)

Abstract

Anthocyanins are secondary metabolites belonging to the flavonoid group which act as pigments or coloring agents in plants that give red, blue and purple colors to flowers, fruits and vegetables. Anthocyanins have several pharmacological activities such as antioxidants, anti-carcinogenic, preventing impaired liver function, anti-hypertensive, and anti-diabetic. The anthocyanin structure consists of an aglycone form which is sterified by several sugar groups (glycones) and acyl groups in several anthocyanin compounds. In an effort to maintain the standard of a drug made from natural ingredients, the process of standardization of active compounds can be carried out to guarantee and maintain safety, quality uniformity and efficacy. This review was conducted to identify the anthocyanins contained in an extract by means of thin layer chromatography (TLC), UV-Vis spectrophotometer, thin layer chromatography-densitometry, and high performance liquid chromatography (HPLC). The research methodology used is in the form of literature review with reference sources related to the review topic obtained from various sources, such as Pubmed, Science Direct, and Google Scholar.
Co-Authors Agustin, Annastya Eka Annisa, Bunga Nur Arob, Izull Ervi, Ervi Febiola Lubis, Christina Firosalia Kristin Indah Laily Hilmi Lina Nurfadhila Lubis, Christina Febiola Marsah Rahmawati Utami Mierza , Vriezka Ningsih, Sri Puji Nurul Sa'adah, Cantika Salman Al Farisi, Salman Al Samian Sa’adah, Cantika Nurul Zakiyah, Wildani