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All Journal International Journal of Integrated Health Sciences Jurnal Kesehatan Andalas
Yani, Made Violin Weda
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Health Professions

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Gambaran Karakteristik Pengetahuan, Sikap dan Perilaku Risiko Covid-19 Dalam Kerangka Desa Adat di Desa Gulingan, Mengwi, Bali Diva Putra, Agus Indra Yudhistira; Pratiwi, Made Sindy Astri; Yani, Made Violin Weda; Gunawan, Gufran Rizaldy Danang; Ganesha, Ghaniy Muhammad; Evelyn Aminawati, Agnes Maria Aprilia; Aryana, I Putu Gede Dharma Wibhawa; Suryawati, I Gusti Agung Alit
Jurnal Kesehatan Andalas Vol. 9 No. 3 (2020): Online September 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i3.1402

Abstract

Desa Gulingan adalah salah satu desa adat di Kecamatan Mengwi yang merupakan peringkat pertama kecamatan dengan kasus tertinggi Covid-19 di Kabupaten Badung sangat berpeluang mengalami peningkatan kasus akibat transmisi lokal. Berdasarkan hal tersebut hingga saat ini belum terdapat hasil deskriptif yang mengkaji pengetahuan, sikap, dan perilaku masyarakat Desa Gulingan dengan sistem sosial kemasyarakatannya yang berbasis budaya dalam kerangka desa adat. Tujuan: Mengetahui gambaran tentang pengetahuan, perilaku, perilaku beresiko Covid-19 pada masyarakat Desa Gulingan dalam kerangka desa adat. Metode: Ini adalah penelitian deskriptif dengan rancangan studi potong lintang dengan jumlah sampel yang memenuhi kriteria inklusi dan eksklusi sebanyak 144 sampel. Hasil kuesioner disajikan dalam bentuk numerik dan kategorik dan selanjutnya dilakukan proses analisis secara univariat dalam variabel. Hasil: Responden penelitian didominasi oleh laki-laki (55,3%), berstatus pendidikan SMA/sederajat (62,3%), status pekerjaan terbanyak adalah pegawai swasta (42,1%), sampel terbanyak diperoleh dari Banjar Angkeb Canging (20, 2%). Hasil kuesioner yang berpengetahuan baik (51,8%) berperilaku baik (66,7%), dan terbukti/berpraktik baik (56,1%) dalam pencegahan Covid-19. Simpulan: Pengetahuan, perilaku, dan sikap pada masyarakat Desa Gulingan yang baik dalam pencegahan virus corona dengan menerapkan kearifan lokal yakni dalam kerangka desa adat di Bali.Kata kunci: covid-19, desa Gulingan, pengetahuan, perilaku, sikap
Predictive Factors of Neutropenia Following First Cycle of Chemotherapy in Patients with Non-Hodgkin’s Lymphoma in Bali, Indonesia Pratiwi, Made Sindy Astri; Agustini, Made Priska Arya; Yani, Made Violin Weda; Rena, Ni Made Renny Anggreni
International Journal of Integrated Health Sciences Vol 13, No 2 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v13n2.4178

Abstract

Background: Chemotherapy-induced neutropenia (CIN) is a common hematologic toxicity that increases infection risk, hospitalization, and treatment delay. Limited data exist on predictive factors of CIN among non-Hodgkin’s lymphoma (NHL) patients in Indonesia, particularly in Bali.Objective: To identify predictive factors of neutropenia following the first cycle of chemotherapy in patients with NHL at Prof. I.G.N.G Ngoerah General Hospital, Bali, Indonesia.Methods: This retrospective cohort study included all NHL patients treated from 2020–2023. Eligible patients were aged ≥18 years, received CHOP-based regimens with or without rituximab, and did not receive G-CSF prophylaxis. Data were obtained from medical records. Assessed risk factors were age, gender, BMI, comorbidities, histopathology grading, extranodal involvement, ECOG status, Ann Arbor stage, IPI score, chemotherapy regimen, pre-treatment blood count, eGFR, LDH, and albumin. The incidence of neutropenia was evaluated after the first chemotherapy cycle.Results: The mean age of the eligible patients (n=112) was 54.53 ± 14.64 years; 46 of them (41%) developed neutropenia. Significant factors associated with neutropenia were histopathology grading (p = 0.030), Ann Arbor stage (p = 0.048), IPI score (p = 0.037), chemotherapy regimen (p = 0.019), and LDH above normal (p = 0.049). Multivariate analysis identified high IPI scores (p = 0.016; OR 6.375; 95% CI 1.416–28.698) and CHOP regimen (p = 0.016; OR 3.033; 95% CI 1.230–7.476) as independent predictors of CIN.Conclusion: High IPI scores and CHOP regimens are strong predictors of neutropenia after the first chemotherapy cycle in NHL patients. Early identification of high-risk patients is essential for preventive management and improved treatment outcomes.
Co-Authors Agustini, Made Priska Arya Aryana, I Putu Gede Dharma Wibhawa Diva Putra, Agus Indra Yudhistira Evelyn Aminawati, Agnes Maria Aprilia Ganesha, Ghaniy Muhammad Gunawan, Gufran Rizaldy Danang I Gusti Agung Alit Suryawati Pratiwi, Made Sindy Astri Rena, Ni Made Renny Anggreni