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All Journal E-Jurnal Medika Udayana International Journal of Integrated Health Sciences Jurnal Kesehatan Andalas Indonesian Journal of Global Health research
Pratiwi, Made Sindy Astri
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Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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KUALITAS DAN DERAJAT NYERI PADA INJEKSI PROPOFOL INTRAVENA DENGAN PEMBERIAN LIDOKAIN INTRAVENA DI RSUP SANGLAH DENPASARr Pratiwi, Made Sindy Astri; Suranadi, I Wayan; Sinardja, I Ketut; Kurniyanta, I Putu
E-Jurnal Medika Udayana Vol 11 No 3 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i03.P01

Abstract

Induksi anestesi menggunakan propofol secara intravena menyebabkan nyeri yang dapat diatasi dengan premedikasi lidokain intravena. Hingga kini, belum ada penelitian terbaru mengenai derajat dan kualitas nyeri akibat induksi propofol dengan premedikasi lidokain intravena di RSUP Sanglah Denpasar. Penelitian ini bertujuan untuk mengukur kedua hal di atas. Desain penelitian ini adalah deskriptif observasi cross-sectional bertempat di RSUP Sanglah Denpasar. Subjek penelitian dipilih dengan consecutive sampling berjumlah 39 pasien berjenis kelamin laki-laki atau perempuan, berusia 18-64 tahun, BMI 18,5-22,9 kg/m2, status fisik ASA I atau II, menjalani operasi elektif dengan propofol intravena dan premedikasi lidokain intravena, serta menandatangani informed consent. Penilaian kualitas nyeri menggunakan SFMP-Q sementara derajat nyeri dinilai menggunakan kombinasi VAS dan NRS. Data yang terkumpul akan dianalisis secara univariat. Nyeri akibat propofol intravena dengan premedikasi lidokain penelitian ini ditemukan tidak nyeri 23,1%, nyeri ringan 74,4%, nyeri sedang 2,6%, dan tidak ada yang mengalami nyeri berat. Lidokain menyebabkan sensitisasi nyeri sensori yang rendah terhadap 80% pasien dan tidak mengalami gangguan afeksi pada 80% pasien. Pada penelitian ini, propofol intravena dengan premedikasi lidokain dapat mengurangi rasa nyeri dengan sensitisasi nyeri yang rendah tanpa gangguan afeksi.
Gambaran Karakteristik Pengetahuan, Sikap dan Perilaku Risiko Covid-19 Dalam Kerangka Desa Adat di Desa Gulingan, Mengwi, Bali Diva Putra, Agus Indra Yudhistira; Pratiwi, Made Sindy Astri; Yani, Made Violin Weda; Gunawan, Gufran Rizaldy Danang; Ganesha, Ghaniy Muhammad; Evelyn Aminawati, Agnes Maria Aprilia; Aryana, I Putu Gede Dharma Wibhawa; Suryawati, I Gusti Agung Alit
Jurnal Kesehatan Andalas Vol. 9 No. 3 (2020): Online September 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i3.1402

Abstract

Desa Gulingan adalah salah satu desa adat di Kecamatan Mengwi yang merupakan peringkat pertama kecamatan dengan kasus tertinggi Covid-19 di Kabupaten Badung sangat berpeluang mengalami peningkatan kasus akibat transmisi lokal. Berdasarkan hal tersebut hingga saat ini belum terdapat hasil deskriptif yang mengkaji pengetahuan, sikap, dan perilaku masyarakat Desa Gulingan dengan sistem sosial kemasyarakatannya yang berbasis budaya dalam kerangka desa adat. Tujuan: Mengetahui gambaran tentang pengetahuan, perilaku, perilaku beresiko Covid-19 pada masyarakat Desa Gulingan dalam kerangka desa adat. Metode: Ini adalah penelitian deskriptif dengan rancangan studi potong lintang dengan jumlah sampel yang memenuhi kriteria inklusi dan eksklusi sebanyak 144 sampel. Hasil kuesioner disajikan dalam bentuk numerik dan kategorik dan selanjutnya dilakukan proses analisis secara univariat dalam variabel. Hasil: Responden penelitian didominasi oleh laki-laki (55,3%), berstatus pendidikan SMA/sederajat (62,3%), status pekerjaan terbanyak adalah pegawai swasta (42,1%), sampel terbanyak diperoleh dari Banjar Angkeb Canging (20, 2%). Hasil kuesioner yang berpengetahuan baik (51,8%) berperilaku baik (66,7%), dan terbukti/berpraktik baik (56,1%) dalam pencegahan Covid-19. Simpulan: Pengetahuan, perilaku, dan sikap pada masyarakat Desa Gulingan yang baik dalam pencegahan virus corona dengan menerapkan kearifan lokal yakni dalam kerangka desa adat di Bali.Kata kunci: covid-19, desa Gulingan, pengetahuan, perilaku, sikap
Diabetic Ketoacidosis in Pregnancy Caused by Multiple Risk Factors: A Case Report Pratiwi, Made Sindy Astri; Wulandari, Dewi Catur
Indonesian Journal of Global Health Research Vol 7 No 4 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i4.6283

Abstract

Pregnant patients with diabetes are susceptible to diabetic ketoacidosis (DKA) but this condition is still underreported. Unknown risk factors during pregnancy will increase morbidity and mortality of DKA. The interaction between multiple risk factors will certainly increase the burden of health care. This report aims to discuss the management of DKA in pregnancy with multiple risk factors, from diagnosis to prevention of complications. This study is descriptive study with case report design. Data were obtained from anamnesis, physical, and supporting examinations at Wangaya Hospital. Data were analyzed qualitatively and presented narratively according to case report format. This paper reports DKA in 39-year-old female with 24 weeks gestational age with shortness of breath. This was her fourth pregnancy. The patient had no history of diabetes and had never undergone pregnancy control. The patient had increased blood pressure and Kussmaul's breathing. Supporting examinations showed leukocytosis, hyperglycemia, bacteriuria, ketonuria, proteinuria, metabolic acidosis, low potassium, while chest x-ray showed pneumonia. The patient was diagnosed DKA with severe preeclampsia, pneumonia, urinary tract infection, and hypokalemia. Unfortunately, the patient experienced IUFD. After aggressive fluid replacement, intravenous insulin, electrolyte correction, treat the causes, and maternal monitoring, the patient showed significant improvement. Various adaptations during pregnancy can lead to DKA. Missed glucose homeostasis screening, oxidative stress, aging of β cells, inflammatory environment with various cytokines, to vascular dysfunction can be pathways for DKA in pregnancy. DKA in pregnancy is a challenge that requires proper risk factor screening. Optimal management and close monitoring are needed to achieve good prognosis.
Predictive Factors of Neutropenia Following First Cycle of Chemotherapy in Patients with Non-Hodgkin’s Lymphoma in Bali, Indonesia Pratiwi, Made Sindy Astri; Agustini, Made Priska Arya; Yani, Made Violin Weda; Rena, Ni Made Renny Anggreni
International Journal of Integrated Health Sciences Vol 13, No 2 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v13n2.4178

Abstract

Background: Chemotherapy-induced neutropenia (CIN) is a common hematologic toxicity that increases infection risk, hospitalization, and treatment delay. Limited data exist on predictive factors of CIN among non-Hodgkin’s lymphoma (NHL) patients in Indonesia, particularly in Bali.Objective: To identify predictive factors of neutropenia following the first cycle of chemotherapy in patients with NHL at Prof. I.G.N.G Ngoerah General Hospital, Bali, Indonesia.Methods: This retrospective cohort study included all NHL patients treated from 2020–2023. Eligible patients were aged ≥18 years, received CHOP-based regimens with or without rituximab, and did not receive G-CSF prophylaxis. Data were obtained from medical records. Assessed risk factors were age, gender, BMI, comorbidities, histopathology grading, extranodal involvement, ECOG status, Ann Arbor stage, IPI score, chemotherapy regimen, pre-treatment blood count, eGFR, LDH, and albumin. The incidence of neutropenia was evaluated after the first chemotherapy cycle.Results: The mean age of the eligible patients (n=112) was 54.53 ± 14.64 years; 46 of them (41%) developed neutropenia. Significant factors associated with neutropenia were histopathology grading (p = 0.030), Ann Arbor stage (p = 0.048), IPI score (p = 0.037), chemotherapy regimen (p = 0.019), and LDH above normal (p = 0.049). Multivariate analysis identified high IPI scores (p = 0.016; OR 6.375; 95% CI 1.416–28.698) and CHOP regimen (p = 0.016; OR 3.033; 95% CI 1.230–7.476) as independent predictors of CIN.Conclusion: High IPI scores and CHOP regimens are strong predictors of neutropenia after the first chemotherapy cycle in NHL patients. Early identification of high-risk patients is essential for preventive management and improved treatment outcomes.
Co-Authors Agustini, Made Priska Arya Aryana, I Putu Gede Dharma Wibhawa Dewi Catur Wulandari Diva Putra, Agus Indra Yudhistira Evelyn Aminawati, Agnes Maria Aprilia Ganesha, Ghaniy Muhammad Gunawan, Gufran Rizaldy Danang I Gusti Agung Alit Suryawati I Ketut Sinardja I Wayan Suranadi Kurniyanta, I Putu Rena, Ni Made Renny Anggreni Yani, Made Violin Weda