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All Journal JURNAL FARMASIMED (JFM) Mejuajua Jurnal Pengmas Kestra (JPK) Medistra Medical Journal (MMJ)
Pranata, Chandra
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Journal : JURNAL FARMASIMED (JFM)

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FORMULASI SEDIAAN MASKER WAJAH MENGGUNAKAN EKSTRAK ETANOL BUNGA KECOMBRANG (ETLINGERA ELATIOR) TERHADAP KELEMBABAN KULIT WAJAH Pranata, Chandra; Boru Situmorang, Novidawati; Marbun, Romauli Anna Teresia
Jurnal FARMASIMED (JFM) Vol 2 No 2 (2020): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v2i2.364

Abstract

ABSTRACT Skin is an essential and vital organ and a reflection of health. Natural antioxidants such as flavonoids, polyphenols and Sapponin are believed to increase moisture on the skin. This ability is the main reason for using Torch Ginger flower extract which is formulated into a form of facial mask in the form of clay facial mask. Objective: To formulate facial moisturizing mask preparations using the extract of Torch Ginger(Etlingera elatior). This study used the Torch Ginger Flower extract facial moisturizing mask formulation method with a concentration of 0 (Blank), 5% and 10%. Evaluation of mask preparations included homogeneity, stability of dosage at temperatures of 80C and 250C, Organoleptic test and pH of preparations. Measurements of skin moisture activity were measured using alar Skin Analyzer which was tested on the face surface 3cm wide. The results showed that the preparation was stable in terms of odor, color and was at a pH of 4.2-6.3 using observations of litmus discoloration. Effectiveness of facial skin moisture with 10% Torch Ginger extract concentration is more effective to produce results at a concentration of 5% and blank. Conclusion: Torch Ginger flower extract can be formulated into preparations of face masks with various concentrations and has the effect of moisturizing the skin and brightening the complexion. Keywords: Torch Ginger Flower Extract, Facial Mask, Clay Facial Mask, Facial Skin Moisture
UJI AKTIVITAS EKSTRAK ETANOL DAUN KARAMUNTING (Rhodomyrtus tomentosa.) TERHADAP PERTUMBUHAN BAKTERI Salmonella thypi Wulandari, Suci; Pranata, Chandra; Sihombing, Yanna Rotua; Nasution, Muhammad Hamim
Jurnal FARMASIMED (JFM) Vol 2 No 2 (2020): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v2i2.382

Abstract

Salmonella thypiis a bacterium that causes typhoid fever. Typhoid fever is an infectious disease that is still a health problem, especially in Indonesia. There are several studies on the types of plants that can control bacterial growth. Indonesian plants are often used as medicine, one of which is the karamunting (Rhodomyrtus tomentosa.). Traditionally a number of parasitic species have been used to prevent and treat various diseases such as cough, anticancer, diuretic, anti-inflammatory, antibacterial, wound or infection karamunting (Rhodomyrtus tomentosa.) Has active compounds such as flavonoids, alkaloids, tannins , saponins, and glycosides which have antibacterial abilities. The purpose of this study is to determine the inhibition of extract of karamunting (Rhodomyrtus tomentosa.) at concentrations of 5%, 10%, and 15%. Test samples using Salmonella thypi. This research is an experimental study with a design (posttest). The research methods included the collection of plant material, determination of plant material, making simplicia, phytochemical screening, making ethanol extract from simplicia by maceration, testing chemical compound groups, and antibacterial testing with paper disk diffusion methods. Karamunting is extracted by maceration process, using 70% ethanol solvent. The results of this study indicate that the benalu coffee leaf extract (Rhodomyrtus tomentosa.) has inhibitory capacity as an antibacterial in Salmonella thypi with a mean inhibition of 16.87 mm at a concentration of 5%, 17.24 mm at a concentration of 10%, and 18.21 mm at a concentration of 15%. The greatest inhibition is produced at a concentration of 15%, because the higher the concentration of the extract, the higher the diameter of the inhibition produced, because the more active substances contained in the extract.
PENGARUH LILIN AROMATERAPI MINYAK LAVENDER (LAVANDULA ANGUSTIFOLIA) TERHADAP KONSENTRASI BELAJAR PADA SISWA MADRASAH TSANAWIYAH AL-WASHLIYAH PASAR MIRING DI DESA PASAR MIRING anggraeni, Ratih; ., Muriati; Pranata, Chandra
Jurnal FARMASIMED (JFM) Vol 3 No 2 (2021): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v3i2.678

Abstract

Aromatherapy is an ancient healing process that uses pure aromatherapy plant extracts aimed at improving the health and well-being of the body, mind and spirit. Lavender contains linalil acetate and linalool. Linalil acetate and linalool have no harmful side effects on health. This substance is antibacterial, fungicidal, viriside, parasiticidal and vermifugal and has neurotonic and uterotonic action. This study aims to determine the effect of lavender oil (Lavandula angustifolia) aromatherapy candles on increasing the concentration of student learning at the Madrasah Tsanawiyah Al-Wasliyah Pasar Miring in Desa Pasar Miring . The study used a quasi-pretest-posttest experimental method for 30 randomly selected students. The instrument in this study used the Army Alpha Test with data analysis using Paired T-Test. Hypothesis testing using Paired T-Test showed p value = 0.026<0.05 (p <0.05). It can be concluded that there is an influence of lavender oil aromatherapy candles on increasing the concentration of student learning in Madrasah Tsanawiyah Al-Wasliyah Pasar Miring in Desa Pasar Miring
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN TALAS (Colococasia Esculenta L.) TERHADAP BAKTERI Escherichia coli Pranata, Chandra; Tarihoran, Sartika Noviani; Darmirani, Yosi
Jurnal FARMASIMED (JFM) Vol 4 No 1 (2021): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i1.793

Abstract

Salah satu tanaman yang sering dijadikan obat adalah daun Talas (Colocasia esculanta L.). Daun talas memiliki kandungan senyawa flavonoid, alkaloid, saponin dan tannin yang memiliki kemampuan untuk menghambat pertumbuhan bakteri. Eschericia coli adalah salah satu jenis bakteri yang dapat menyebabkan infeksi pada pencernaan. Salah satu tujuan penelitian ini untuk mengetahui aktivitas antibakteri daun talas dengan konsentrasi yang paling efektif dalam menghambat bakteri Eschericia coli. Penelitian ini adalah penelitian eksperimental murni. Daun talas aktivitas antibakteri dilakukan dengan metode difusi cakram. Penelitian dilakukan dengan 3 variasi konsentrasi yang berbeda. Hasil penelitian menunjukkan bahwa ada aktivitas antibakteri pada setiap konsentrasi. Kesimpulan pemberian aktivitas daun talas dengan konsentrasi 15%, 25%, dan 35% memberikan daya hambat pertumbuhan bakteri paling efektif dengan kosentrasi 25%, 35% yang termasuk dalam kategori kuat. Saran diharapkan kepada peneliti selanjutnya dapat melakukan uji terhadap bakteri lain dan membuat formulasi dari ekstrak daun talas.
TESTING THE EFFECTIVENESS OF FORMULATION OF ANTIFUNCIAL PREPARATION OF GARLIC (ALLIUM SATIVUM L.) ETHANOL EXTRACT MOUNTWASH ON THE GROWTH OF CANDIDA ALBICANS Pranata, Chandra; Sundara, Putri; ., Evi
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1024

Abstract

Telah dilakukan penelitian tentang uji efektivitas formulasi sediaan antifungi obat kumur ekstrak etanol bawang putih (Allium sativum L.) Terhadap pertumbuhan jamur Candida albicans. Ekstrak etanol bawang putih mengandung beberapa senyawa metabolit sekunder, dimana yang berperan sebagai antijamur adalah alkaloid, flavonoid, saponin, dan tanin. Obat kumur ekstrak etanol bawang putih dibuat menjadi lima formula yaitu F0 (basis), F1 (ekstrak etanol bawang putih 15%), F2 (ekstrak etanol bawang putih 25%), F3 (ekstrak etanol bawang putih 50%), dan F4 (ekstrak etanol bawang putih 100%). Evaluasi obat kumur meliputi pemeriksaan Organoleptis, dan Homogenitas. Uji aktivitas antijamur sediaan obat kumur dilakukan dengan metode difusi agar dan dianalisis menggunakan ANOVA satu arah. Hasil evaluasi menunjukkan bahwa sifat fisik sediaan obat kumur memberikan hasil yang baik dan memenuhi syarat sediaan obat kumur. Hasil uji aktivitas antijamur sediaan obat kumur memberikan diameter rata-rata daya hambat sebesar F1 (12,3 mm), F2 (17,3 mm), F3 (18,5 mm) dan F4 (21,6 mm).
EFFECT OF PROCESSING VARIOUS TYPES OF RICE ON CARBOHYDRATE LEVELS Pranata, Chandra; Silalahi, Jansen; ., Yuandani; Cintya, H
Jurnal FARMASIMED (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i1.1111

Abstract

Beras adalah salah satu makanan pokok di Indonesia yang mempunyai kandungan karbohidrat yang cukup tinggi antara 70 – 80 %. Zaman sekarang ada berapa cara untuk mengelolah beras menjadi nasi yakni dengan cara kukus dan menggunakan ricecooker. Tujuan dari penelitian ini adalah untuk menetukan kadar karbohidrat pada beras putih, beras merah dan beras hitam sebelum dan sesudah mengalami pengolahan menggunakan metode luff schrool. Berdasarkan hasil pemeriksaan karbohidrat dari beras putih, beras merah dan beras hitam sebelum dan sesudah mengalami pengolahan maka didapatkan hasil pemeriksaan sebelum mengalami pengolahan kadar karbohidrat tertinggi adalah pada beras putih 52,56 ± 0,20 % dan terendah beras hitam 40,47 ± 0,20 %, sedangkan jika dilihat dari cara pengolahan untuk kadar karbohidrat terendah terdapat pada beras hitam kukus dengan kadar 6,00± 0,20% sementara tertinggi pada beras putih ricecooker 14,00 ±1,4 % sehingga didapatkan kesimpulan bahwa adanya pengaruh pengolahan dalam penurunan kadar karbohidrat dalam beras. Kata Kunci: Karbohidrat, Pengolahan, Beras
TRANSPARENT SOAP FORMULATION WITH VARIOUS LEVELS OF CONCENTRATION OF TEAK LEAF EXTRACT (TECTONA GRANDIS L.F.)AS ANTIBACTERIAL SOAP Pranata, Chandra; Irwanto, Reno; .S, Aminah
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1401

Abstract

The purpose of this study was to examine the organoleptic, homogeneity and antibacterial properties of transparent soap. The treatment used is; F1 (3% teak leaf extract), F2 (6% teak leaf extract), F3 (9% teak leaf extract), and F4 (12% teak leaf extract). The implementation of the research begins with product optimization in advance of the proportion of the use of raw material components. The results of the homogeneity test experiment showed that all formulas were homogeneous and in accordance with SNI standards, then the results of the water content obtained from each preparation proved to meet the requirements set by SNI ( Indonesian National Standard). The results of the pH measurements showed that at pH F0 it remained at 8. The results for measuring pH F1 showed results with a pH of 8. Meanwhile, pH F2 had a pH of 8. The last measurement for pH at pH F3 showed the same pH results as the other formula, namely at pH 8. So that F0, F1, F2, and F3 have the same pH, namely pH 8, where pH 8 is the pH of the positive control, namely soap on the market. Staphylococcus aureus with a concentration of 3% by 13 mm, 6% by 15 mm, 9% by 17 mm, 12% by 20 mm. The greater the concentration of teak leaf extract in transparent solid coir, the greater the inhibition of bacterial growth.
ANTIBACTERIAL ACTIVITY TEST OF CELERY LEAF ETHANOL EXTRACT (APIUM GRAVEOLENS L.) AGAINST BACTERIA STREPTOCOCCUS SANGUINIS Pranata, Chandra; Renty Monica; Asti Pratiwi; Yosi Darmirani
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Health is a very important part of human life, especially oral health. Diseases that occur due to lack of oral hygiene include gingivitis caused by Streptococcus sanguinis bacteria. Chlorhexidine is a solution that is used to clean the oral cavity and prevent plaque formation on the teeth. An alternative mouthwash that comes from nature is celery leaves (Apium graveolens L.) with secondary metabolites, namely alkaloids, flavonoids, saponins and tannins. This study was conducted to determine the antibacterial activity of celery leaf ethanol extract against Streptococcus sanguinis bacteria at concentrations of 12.5%, 25%, 50% and 100% using the disc diffusion method with chlorhexidine as a positive control and Aquadest as a negative control. The celery leaf extraction method was carried out by maceration method using 96% ethanol solvent. The results of the inhibition test with a concentration of 12.5%, 25%, 50% and 100% celery leaf ethanol extract can inhibit the growth of Streptococcus sanguinis bacteria with an average diameter of the inhibition zone in the negative control group (aquadest) is 0 mm, 12.5% concentration is 8.15 mm, at 25% concentration is 7.95 mm, 50% concentration is 9.05 mm, 100% concentration is 9.9 mm, while in chlorhexidine (positive control) an average of 17.83 mm is obtained. From these results, it can be concluded that there is activity of celery leaf ethanol extract against the growth of Streptococcus sanguinis bacteria with a concentration that effectively inhibits the growth of Streptococcus sanguinis bacteria is 100% concentration. Keywords: Celery Leaf, Gingivitis, Streptococcus sanguinis
Antibacterial activity test of dragon scale leaf ethanol extract (drymoglossum piloselloides) againts bacteria Staphyloccocues epidermidis Pranata, Chandra
Jurnal FARMASIMED (JFM) Vol 6 No 2 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i2.2041

Abstract

Daun Sisik Naga (Drymogglossum Piloselloides) merupakan salah satu tumbuhan alami yang paling mudah ditemukan di indonesia. Secara tradisional daun sisik naga merupakan salah satu tanaman herbal yang mampu digunakan untuk pengobatan antikanker, antioksidan kuat dan anti peradangan. Tumbuhan ini memiliki senyawa metabolit sekunder berupa flavonoid, tanin, saponin yang memiliki efek sebagai antibakteri karena dapat menghambat pertumbuhan bakteri Staphyloccocus Epidermidis penyebab jerawat. Staphyloccocus Epidermidis adalah salah satu spesies bakteri dari genus Staphyloccocus yang termasuk gram positif. Tujuan : Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak etanol daun sisik naga terhadap pertumbuhan bakteri Staphyloccocus Epidermidis. Penelitian ini merupakan penelitian Eksperimental. Metode: Metode yang digunakan untuk pengujian aktivitas antibakteri adalah metode agar menggunakan kertas cakram dengan menggunakan 3 sampel dengan konsentrasi 10%, 15% dan 20%. Kontrol Positif berupa Tetrasiklin dan Kontrol Negatif berupa aquadest. Hasil: Penelitian ini menunjukkan bahwa ekstrak etanol daun sisik naga konsentrasi 20 % dengan diameter zona hambat 18,53 mm (kategori kuat), pada konsentrasi 15 % dengan diamter zona hambat 16,46 mm (kategori kuat) dan pada konsentrasi 10 % diameter zona hambat 14,41 mm (kategori kuat). Kesimpulan: Penelitian ini membuktikan bahwa ekstrak etanol daun sisik naga memiliki daya antibakteri terhadap bakteri Staphyloccocus Epidermidis dengan konsentrasi efektif 20 % dengan kategori kuat sebesar 18,53 mm.
Test of the Anti-Inflammatory Effectiveness of Ethanol Extract of Cat's Whiskers Leaves (Orthisiphon Aristatus) on Paw Edema in Male Mice (Mus Musculus) Pranata, Chandra; Darmirani, Yosi; Limbing, Reida
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2289

Abstract

Cat's whisker leaves contain secondary metabolite compounds, flavonoids and essential oils. The chemical compounds contained in cat's whisker leaves have antioxidant, antibacterial, anti-inflammatory and antifungal properties. Flavonoids are known to function as anti-inflammatories by inhibiting pro-inflammatory enzymes, namely by blocking cyclooxygenase or lipoxygenase, can influence cellular signaling pathways such as NF-kB which can inhibit the migration of inflammatory cells to areas of inflammation. Objective: to test the anti-inflammatory effectiveness of ethanol extract of cat's whisker leaves in-vivo. Method: Anti-inflammatory effectiveness testing was carried out on male mice (Mus musculus) by inducing edema on the soles of their feet using 0.1 ml of 1% carrageenan. This research was an experimental study with 5 treatments and 5 replications. The parameters observed were edema volume, edema percentage, and edema inhibition percentage. Edema volume measurements were taken every 60 minutes for 6 hours. The results of measuring the volume of edema were used to calculate the percentage of edema, which was then used to calculate the percentage of edema inhibition. Data on the percentage of edema inhibition were statistically analyzed using the One Way ANOVA test. Result: the results of statistical tests showed significant differences in data on the percentage of edema inhibition and the percentage of edema between treatment groups showing p<0.05. From the results of the percentage of edema inhibition, it shows that cat's whisker leaf extract with a concentration of 15% has the best anti-inflammatory effect, namely inhibition of 88.42% is the concentration with the optimum dose.
Co-Authors ., Evi ., Muriati ., Yuandani .S, Aminah Asti Pratiwi Cintya, H Darmirani, Yosi Dicky Yuswardi Wiratma Harahap, Hasni Yaturramadhan Herlina H Jansen Silalahi Limbing, Reida Nasution, Muhammad Hamim Novidawati Boru Situmorang Octora, Debi Dinha Pratiwi, Asti Ramadhani, Lili Ratih Anggraeni Reno Irwanto Renty Monica Samran, Samran Santika, Rimma Siahaan, Safrika Juliana Sihombing, Yanna Rotua Siregar, Riwandi Suci Wulandari Sumardi . sumitra, Jhoti Sundara, Putri Suprianto Suprianto Syarifuddin, Aminah Tarihoran, Sartika Noviani Yana, Sri Nur Yosi Darmirani