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All Journal Jurnal Biologi Tropis JURNAL FARMASIMED (JFM) Jurnal Farmasi Sains dan Praktis Jurnal Kebidanan, Keperawatan dan Kesehatan (J-BIKES) Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Khairani, Tetty Noverita
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Jurnal Biologi Tropis

 1 
Antifungal Activity Test of Jamaican Cherry Leaf (Muntingia calabura l.) Ethanol Extract in Inhibiting Growth of Fungi Malassezia furfur and Pityrosporum ovale Khairani, Tetty Noverita; Neswita, Elfia; Nurasni, Nurasni; Fitri, Khairani; Amanda, Asri
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9510

Abstract

The plant species known as Jamaican Cherry Leaf (Muntingia calabura L.) belongs to the Muntingiaceae family. Flavonoid compounds, tannins, saponins, and steroids are all found in Jamaican cherry leaves. One of them has antifungals that can stop Pityrosporum ovale and Malassezia furfur from growing, and it is utilized as a traditional medication. This study aimed to determine the antifungal activity and the most effective concentration of Jamaican cherry leaves in inhibiting the growth of Malassezia furfur and Pityrosporum ovale fungi. Methods research is an experimental research. The research phase includes sampling, making simplicia, extract making, testing the characteristics of simplicia and extract, testing the inhibitory power of ethanol extract of Jamaican cherry leaf against fungi (Malassezia furfur and Pityrosporum ovale) by comparing the 2% ketoconazole antibiotic. The results showed the inhibition of ethanol extract of Jamaican cherry leaf (Muntingia calabura L.) against the growth of Malassezia furfur at F1 (7.2 mm), F2 (9.8 mm), F3 (11 mm) with and F4 (6.8 mm). mm) while against the growth of the fungus Pityrosporum ovale at F1 (7.0 mm), F2 (9.11 mm), F3 (10.2 mm) and F4 (6.3 mm). The best inhibition zone was formed at 30% concentration treatment with strong category. The conclusion shows that the ethanol extract of Jamaican cherry leaf (Muntingia calabura L.) can inhibit the growth of Malassezia furfur and Pityrosporum ovale fungi.
Anti-Fungal Activity Testing of Purple Cabbage (Brassica oleracea Linn.) Ethanol Extract in Inhibiting The Fungi Growth Candida albicans and Malassezia furfur Khairani, Tetty Noverita; Fitri, Khairani; Andry, Muhammad; Sarumaha, Paska Eli
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.8009

Abstract

One of the plants that has the potential to be utilized as medicine is purple cabbage (Brassica oleracea Linn.). Commensal fungi like Candida albicans and Malassezia furfur can be found in the genitourinary tract, vagina, urethra, skin, fingers, and toes, among other places on the body. The purpose of: The study aimed to learn more about the antifungal properties of the ethanol extract of purple cabbage in preventing the growth of Malassezia furfur and Candida albicans. This study used an experimental design to examine the independent variables of the purple cabbage extract with various doses of the growth activity test of Candida albicans and Malassezia furfur, as well as their inhibition zones. Purple cabbage contains steroids, saponins, tannins, and flavonoid compounds. With concentrations of 10%, 20%, 30%, and positive control, the average diameter of the inhibitory zone for Candida albicans was 4.83 mm, 7.2mm, 8.75mm, and 6.21mm. The concentrations of Malassezia furfur at 10%, 20%, 30%, and the positive control were 4.61mm, 6.36mm, 8.83mm, and 6.15mm, respectively. As a negative control, DMSO failed to exhibit an inhibitory zone. Statistics revealed a substantial difference, indicating that the concentration had an impact on how the inhibition zone developed. The ethanol extract of purple cabbage has antifungal action, and the treatment with the 30% extract concentration forms the optimal concentration. It is advised that more research be done on the antifungal activity of purple cabbage extract against various kinds of fungus and that dosage forms be created for it.
Co-Authors Abadi, Hafizhatul Amanda, Asri Diana, Vivi Eulis Fadhillah, Annisa Nur Fhitriana, Suzan Fitri, Khairani Handayani, Sri Khairani Fitri Muhammad Amin Nasution Muhammad Andry Muhammad Andry Nasution, Rizka Hasmi Neswita, Elfia nurasni, nurasni Nurussakinah, Nurussakinah Sarumaha, Paska Eli Sundari, Tri Tarigan, Jacub Utari, Sri