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Lestari, Utami Sasmita
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Profil Penetrasi Sediaan Gel Antioksidan Ekstrak Kayu Manis (Cinnamomum burmanii) dengan Variasi Hydrocolloid sebagai Gelling agent Siampa, Jainer Pasca; Wiyono, Weny Indayany; Lestari, Utami Sasmita; Lebang, Julianri Sari; Antasionasti, Irma
Jurnal MIPA Vol 11, No 1 (2022)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jm.v11i1.35787

Abstract

The exposure of sunlight consisting UV radiation has been reported to be the main cause of skin cancer and contribute about 80% of the incidence of skin damage. In an attempt to overcome this problem, antioxidant agents have been used both orally and topically. Compared to oral administration, topical route has been found to be preferred due to the direct action to the desired site. Amongst topical preparation, gel possesses numerous because it provides a cool and fresh sensation. Here, we developed gel antioxidant containing cinnamon extract as active ingredient. Cinnamon was selected as it has a very strong antioxidant activity. This study aimed to obtain the penetration profile of the antioxidant gel of cinnamon extract prepared from two different hydrocolloid agents. The gels were made using various concentrations of Carbopol 940 and NaCMC. The prepared gels were further characterized for their antioxidant capacities using the DPPH free radical scavenging method and their total phenolic contents using the spectrophotometric method. The formulation possessing the strongest antioxidant capacity was continued for ex vivo penetration study using Franz diffusion cells. The results exhibited that the total phenolic value of the cinnamon extract obtained was 908.38 ± 6.54 mg GAE/g extract. The penetration percentages for the formula with Carbopol and NaCMC bases were 53.310 ± 1.217% and 27.969 ± 1.151%, respectively, and the retention percentages were 28.495 ± 0.031% and 18.356 ± 0.191%, respectively. Based on these findings, we concluded that cinnamon extract could potentially be formulated into antioxidant gel preparations and formulas based on Carbopol showed the best penetration profile.
UJI AKTIVITAS ANTIOKSIDAN, ANALISIS TOTAL FENOL, FLAVONID DAN TANIN DARI EKSTRAK BUAH SALAK Datu, Olvie Syenni; Lebang, Julianri Sari; Lestari, Utami Sasmita
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 6 No. 2 (2023): Vol. 6, No.2, 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v6i2.52373

Abstract

Diabetes mellitus (DM) is a global problem that affects many people and causes high morbidity and mortality rates. The pathogenesis of DM is linked to the influence of free radicals, and various studies have been conducted to overcome this problem by utilizing potential natural materials that are available and have medicinal effects. North Sulawesi has a variety of potential plants and fruits that can be utilized for health, one of which is snake fruit. This study aims to determine the antioxidant activity, phenol content, flavonoids, and tannins in salak fruit extract. The research method used was maceration using 96% ethanol solvent, then evaporated to obtain a thick extract. The extract was then tested for total phenolics, flavonoids and tannins using a uv-vis spectrophotometer. Total phenolic content was determined using Folin-Ciocalteu reagent with gallic acid as a comparator. Total flavonoid content was determined with quercetin using AlCl3 reagent. Tannin content was determined with tannic acid. The results showed that the total phenolic content of salak fruit extract was 29.44 ± 1.02 mg Gallic Acid Equivalent (GAE)/g extract, while the total flavonoid content was 8,609 ± 1.69 mg Quercetin Equivalent (QE)/g extract. And the tannin content was 0.08184 ± 0.02 mg tannic acid equivalent (TAE)/g extract. The IC50 value of salak fruit extract is 22.16 which is included in the strong antioxidant category. Based on these results, salak fruit has the potential to be developed into pharmaceutical preparations that can be used to prevent or treat degenerative diseases.
Tempe Drink Making Training, Physical Activity Education and Optimization of Madrasah Health Units for Madrasah Teachers in Manado Lestari, Utami Sasmita; Angmalisang, Elvin Clara; Jayanti, Meilani
Abdimas Galuh Vol 6, No 2 (2024): September 2024
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v6i2.16113

Abstract

Adolescence is a transition period from childhood to adulthood. Adolescence can be an indicator of health in adulthood. Consumption patterns and low physical activity in adolescents trigger obesity which is a risk factor for dyslipidemia. Tempe contains protein that affects the improvement of lipid profiles. Modifying tempe into tempe drinks makes the serving is more practical and preferred by adolescents. This activity aimed to improve the role of madrasah teachers in preventing dyslipidemia among adolescent girls through training in making tempe drinks, physical activity education and optimization of UKM. Teachers are figures who directly deal with adolescents who are students to transfer knowledge and skills in healthy living behaviors. The process of providing health education also needs to be supported by qualified facilities and infrastructure, through optimization of madrasah health units functions and programs. A total of 26 madrasah teachers participated in this activity. This activity was carried out with several stages of activities. They were counseling on dyslipidemia and the potential of tempe drinks as an effort to prevent dyslipidemia in adolescent girls and continued with training on making tempe drinks. Furthermore, counseling on physical activity and training on optimizing the function of UKM and developing health promotion media. The results of this community service activity were expected to improve the quality of adolescent health and could be implemented in the form of sustainable programs by academicians at the madrasah.
PELATIHAN PEMBUATAN SNACK BAR TEMPE DALAM UPAYA PENANGGULANGAN ANEMIA REMAJA PUTRI Lestari, Utami Sasmita; Angmalisang, Elvin Clara; Wijaya, Nur Anindhita Kurniawaty
Jurnal Abdi Insani Vol 11 No 4 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i4.2055

Abstract

Anemia is the most common nutritional problem in the world. The increased need for iron in adolescents because they are in a period of growth makes adolescents very susceptible to anemia, especially in adolescent girls. Anemia can reduce fitness, productivity, learning ability, and cognitive abilities of adolescents. One effort that can be made to overcome anemia is providing tempe snack bar. Modifying tempe into tempe snack bars makes serving tempe more practical and preferred by adolescents. The purpose of this community service activity was to overcome the problem of anemia in adolescent girls by increasing the role of madrasah teachers through training in making tempe snack bars. The target of this service was madrasah teachers. The activity was carried out in the counseling stage, lectures and discussions about anemia and the benefits of tempe, especially in overcoming anemia in adolescent girls, followed by training in making tempe snack bars. The results of this community service activity hopely can be used as a solution to prevent and overcome anemia in adolescent girls. Providing motivation and awareness to adolescent girls to consume nutritious foods containing iron. This counseling activity is considered effective in changing the behavior of adolescent girls in preventing anemia. Keywords: anemia, tempe snack bar, adolescent, girls
Edukasi Gizi, Suplemen Kesehatan, Aktivitas Fisik dan Pemanfaatan Aplikasi Berbasis Android sebagai Sumber Informasi Kesehatan Remaja Lestari, Utami Sasmita; Angmalisang, Elvin Clara; Jayanti, Meilani
Abdimas Galuh Vol 7, No 2 (2025): September 2025
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v7i2.21059

Abstract

Obesitas pada remaja merupakan salah satu masalah kesehatan yang semakin meningkat, termasuk dikalangan santri di lingkungan pesantren. Pola makan tinggi kalori, rendahnya aktivitas fisik, serta konsumsi suplemen secara sembarangan menjadi faktor risiko utama yang teridentifikasi di MTS Assalam Manado. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan literasi kesehatan remaja melalui empat pendekatan utama, yaitu edukasi mengenai obesitas dan gizi seimbang beserta pengenalan snack bar tempe sebagai camilan sehat, edukasi mengenai suplemen kesehatan yang aman, edukasi aktivitas fisik, serta pemanfaatan aplikasi kesehatan berbasis android. Metode yang digunakan berupa ceramah interaktif, diskusi, praktik pembuatan snack bar tempe, demonstrasi olahraga sederhana, serta pelatihan penggunaan aplikasi digital. Hasil kegiatan menunjukkan peningkatan pengetahuan santri yang dibuktikan dengan perbedaan skor rata-rata pre-test dan post-test sebesar 35%. Selain itu, sebagian besar santri mulai mengurangi konsumsi camilan tinggi kalori, beralih pada camilan sehat, dan menunjukkan motivasi baru dalam beraktivitas fisik. Pemanfaatan aplikasi android juga memudahkan santri dalam memantau pola makan dan aktivitas harian. Program ini terbukti efektif dalam meningkatkan kesadaran dan perilaku hidup sehat, meskipun masih terdapat tantangan dalam menjaga konsistensi aktivitas fisik. Disarankan agar program ini dilakukan secara berkelanjutan dengan melibatkan pihak sekolah, guru, dan orang tua, serta pengembangan aplikasi kesehatan dengan fitur yang lebih interaktif agar dapat memperkuat keberlanjutan intervensi.
Penyuluhan Keamanan Jajanan Sehat pada Anak Usia Sekolah Antasionasti, Irma; Abdullah, Surya Sumantri; Lestari, Utami Sasmita; Jayanto, Imam; Hariyanto, Yuanita Amalia
Jurnal Lentera: Penelitian dan Pengabdian Masyarakat Vol. 5 No. 2 (2024): Jurnal Lentera - Penelitian dan Pengabdian Masyarakat
Publisher : Yayasan Bina Lentera Insan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57207/pa34x951

Abstract

Pangan jajanan di sekolah memegang peranan penting dalam memberikan asupan energi dan zat gizi bagi anak usia sekolah. Namun, faktor keamanan pangan jajanan perlu menjadi perhatian. Oleh karena itu, perlu dilakukan penyuluhan keamanan jajanan sehat pada anak usia sekolah. Kegiatan dilakukan melalui 3 tahapan yang terdiri dari tahap persiapan, tahap pelaksanaan dan tahap evaluasi. Sebanyak 28 orang mengikuti kegiatan yang terdiri dari 25 anak usia sekolah dan 3 guru/pengurus Yayasan Hidayatullah Tomohon. Materi yang diberikan dalam kegiatan penyuluhan yaitu pangan jajanan anak sekolah, 5 kunci keamanan pangan untuk anak sekolah, dan bahan tambahan pangan. Hasil rerata nilai pre test dari peserta adalah 0,83 dan post test adalah 0,97 (dari rentang nilai 1,00). Terdapat peningkatan nilai sebesar 0,14 setelah dilaksanakan kegiatan penyuluhan. Hal ini menunjukkan bahwa kegiatan penyuluhan berlangsung dengan baik sehingga materi dapat dipahami oleh peserta.
Relationship between body mass index and postural balance and flexibility in adolescent girls Lestari, Utami Sasmita; Angmalisang, Elvin Clara; Wijaya, Nur Anindhita Kurniawaty; Wirawanti, Ika Wirya
Science Midwifery Vol 12 No 3 (2024): August: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i3.1644

Abstract

Adolescence is a transition period from childhood to adulthood which is marked by many changes. Adolescents generally have a sedentary lifestyle which causes an increase in body mass index. An increase in body mass index has a negative impact on postural balance and flexibility. Excessive fat in the body tends to change the location of the body's center of gravity and limit joint movement. This study aimed to determine the relationship between body mass index and postural balance and flexibility in adolescent girls. This research was a correlation study and used a cross sectional research design with a total of 35 young women. The parameters used to measure postural balance are the Y-balance test and flexibility is the sit-and-reach test. The data analysis used in this research is Pearson correlation analysis. The results showed that there was a significant relationship between body mass index and postural balance (p=0.001) and flexibility (p=0.001) and the level of closeness of the relationship between each variable was very strong (r=0.825). The higher the BMI, the lower the postural balance and flexibility.
Co-Authors Abdullah, Surya Sumantri Angmalisang, Elvin Clara Antasionasti, Irma Datu, Olvie Syenni Hariyanto, Yuanita Amalia Jayanto, Imam Julianri Sari Lebang, Julianri Sari Meilani Jayanti Siampa, Jainer Pasca Wijaya, Nur Anindhita Kurniawaty Wirawanti, Ika Wirya Wiyono, Weny Indayany