The increasing complexity and volume of health data in modern biomedical systems have necessitated advanced technologies for effective data processing and analysis. Traditional methods often fall short in managing real-time, multidimensional data generated from various biomedical sources, such as electronic health records (EHRs), wearable devices, and genomic data. This research investigates the application of artificial intelligence (AI) in optimizing the processing and interpretation of biomedical health data. The objective of this study is to explore how AI-based technologies, including machine learning and deep learning algorithms, enhance the efficiency, accuracy, and predictive capabilities in biomedical information systems. By identifying patterns, anomalies, and correlations in large datasets, AI offers potential improvements in disease diagnosis, patient monitoring, and treatment personalization. This research employs a qualitative systematic review method, analyzing peer-reviewed literature published between 2015 and 2024 from major databases such as PubMed, IEEE Xplore, and Scopus. The analysis focuses on case studies, comparative evaluations, and implementation outcomes of AI in various biomedical domains. The findings reveal that AI applications significantly improve data processing speed and accuracy, enable early diagnosis of diseases such as cancer and diabetes, and support predictive analytics for patient outcomes. However, challenges remain in areas such as data privacy, ethical compliance, and algorithm transparency. In conclusion, the integration of AI into biomedical data systems holds transformative potential for healthcare delivery, though further interdisciplinary collaboration is required to address its limitations and ensure equitable access and ethical use.