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The Effect Of Coenzim Q10 On The Number Of Lymfocite Cells In Male Wistar Rats With Periodontitis Tara Yurian Nadhifa; Aprilia Yuanita Anwaristi; Nur Ariska Nugrahani; Dwi Kurniawati
Jurnal EduHealth Vol. 14 No. 03 (2023): Jurnal EduHealt, Edition September 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54209/jurnaleduhealth.v14i3.2621

Abstract

Periodontal disease is a dental and oral health problem in adult society. One of the periodontal diseases is periodontitis which is an inflammation of the periodontal tissue caused by accumulation of dental plaque which can lead to impaired masticatory function, tooth loss, alveolar bone damage, periodontal ligament damage, pocket formation, and gingival recession. Coenzyme Q10 acts as an antioxidant, the reduced form is ready to give electrons to deactivate ROS or block free radicals which can prevent oxidative stress thereby protecting lymphocyte cells and reducing the immune response which can lead to a reduction in inflammation in the periodontal tissues. The purpose of this study was to determine the effect of coenzyme Q10 on the number of lymphocyte cells in the gingiva of male wistar rats with periodontitis. The research method used is true experimental laboratory quantitative research with a research design that is a posttest only control group design with observation or observing the control group and the treatment group. The number of samples used was 24 rats. Observation of lymphocyte cells was carried out using a light microscope with a magnification of 200x and a magnification of 400x and then counted manually by the observer. The results showed that the significance value obtained in the One-Way ANOVA test was 0.000 (<0.05). Then, based on the results of the Post Hoc Least Significant Difference (LSD) test, it was found that the biggest difference in effect was in the K(-)5 group and the P5 group, where the difference was 59.00 with a significance value of 0.000 (<0.05). It can be concluded that there is an effect of coenzyme Q10 administration on the number of lymphocyte cells in the gingiva of male Wistar rats with periodontitis.
MEWUJUDKAN GERAKAN SADAR SEHAT PADA ANAK MELALUI PENYULUHAN KESEHATAN GIGI DAN MULUT Aprilia Yuanita Anwaristi; Nendika Dyah Ayu Murika Sari; Cahyani Cahyani; Morita Sari; Ikmal Hafizi; Nur Ariska Nugrahani; Gusti Dhika Zafira
GANESHA: Jurnal Pengabdian Masyarakat Vol. 3 No. 2 (2023): Juli 2023
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Tunas Pembangunan Surakarta (UTP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36728/ganesha.v3i2.2555

Abstract

Aspek kesehatan Anak Usia Dini yang perlu diperhatikan salah satunya adalah kesehatan gigi dan mulut. Kegiatan UKGS belum pernah dilakukan di SD Negeri Krikilan Dua, Kecamatan Masaran, Kabupaten Sragen. Guru dan siswa belum pernah mendapatkan materi pelatihan tentang cara menyikat gigi yang benar untuk menjaga kesehatan gigi pada saat pandemi covid 19. Tujuan kegiatan ini adalah terciptanya gerakan masyarakat sadar sehat pada anak terutama pada kesehatan gigi selama pandemi covid-19. Metode penyuluhan dilakukan dalam beberapa tahap meliputi persiapan, pelaksanaan dan evaluasi. Kesadaran akan kesehatan gigi pada anak sekolah dasar selama pandemi adalah kurang, dikarenakan program UKGS juga tidak dapat berjalan dengan baik. Penyuluhan cara menyikat gigi yang benar untuk menjaga kesehatan gigi dan mulut mampu meningkatkan pengetahuan anak-anak sekolah dasar dari yang berpengetahuan kurang menjadi baik dan sangat baik. Upaya lanjutan perlu dilakukan misalnya dengan sikat gigi bersama dan cek kesahatan gigi oleh tim penyuluh.
Pengaruh Ozonated Olive Oil terhadap Jumlah Osteoblas pada Gingiva Tikus Wistar Jantan yang Mengalami Periodontitis Anwaristi, Aprilia Yuanita; Arifin, Dani Fajar
Health & Medical Sciences Vol. 1 No. 1 (2023): November
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v1i1.64

Abstract

Latar Belakang: Periodontitis disebabkan adanya penumpukan bakteri plak pada permukaan gigi. Pengobatan pada penyakit periodontitis secara mekanis juga harus menggunakan pengobatan kimiawi lokal yang diutamakan dibanding pengobatan sistemik seperti antibiotik. Ozonated olive oil sebagai terapi tambahan tidak menimbulkan rasa sakit dan dapat digunakan sebagai antiseptik dalam perawatan non-bedah penyakit periodontal. Ozon juga memiliki spektrum aktivitas yang luas tetapi dengan toksisitas rendah, memberikan keuntungan pada perawatan lokal ini sebelum pengembangan zat dengan aksi yang lebih spesifik pada mikro- organisme yang terkait dengan periodontitis. Metode: Penelitian ini merupakan jenis penelitian true experimental laboratorium dengan rancangan penelitian Posttest-Only Control Group dan terdapat dua kelompok kontrol yaitu, kelompok kontrol dan kelompok perlakuan. sampel terdiri atas 24 tikus wistar jantan diinkubasi periodontitis dibagi menjadi 2 kelompok berdasarkan hari, kelompok kontrol dan kelompok perlakuan. sampel dianalisis secara histologis pada hari ke- 7 dan 14. Hasil: Hasil uji hipotesis menemukan bahwa nilai signifikansi p 0,00 (p<0,05), hasil tersebut menunjukkan bahwa terdapat perbedaan yang signifikan jumlah sel osteoblas antara kelompok perlakuan ozonated olive oil dengan kelompok kontrol. Hasil Uji Post Hoc LSD menunjukkan bahwa kelompok perlakuan memiliki perbedaan bermakna antara kelompok kontrol dan perlakuan memiliki tingkat signifikansi (p<0,05). Kesimpulan: Penelitian yang telah dilakukan menghasilkan kesimpulan bahwa pemberian ozonated olive oil dapat mempengaruhi jumlah sel osteoblas berperan dalam proses penyembuhan periodontitis pada tikus putih (rattus novergicus) galur wistar jantan.
Efektivitas Gel Ekstrak Daun Binahong (Anredera cordifolia) 5% Terhadap Jumlah Neutrofil pada Proses Penyembuhan Luka Pasca Pencabutan Gigi Tikus strain Wistar Azizah, Khoirunisa Ulayya; Anwaristi, Aprilia Yuanita; Kurniawati, Dwi; Ningsih, Juwita Raditya
ARTERI : Jurnal Ilmu Kesehatan Vol 5 No 3 (2024): Mei
Publisher : Puslitbang Sinergis Asa Professional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/arteri.v5i3.434

Abstract

The process of tooth extraction can cause injury and trigger healing stages involving soft tissue and alveolar bone. The stages of healing include hemostasis, inflammation, proliferation, and remodeling. The use of NSAIDs for wound healing can cause side effects, so it is necessary to look for alternatives such as binahong leaf gel extract. To determine the effectiveness of 5% concentration of binahong leaf extract gel on the number of neutrophils in wound healing after tooth extraction in Wistar rats. This study is expected to be a foundation for the development of further research on alternative treatments using 5% binahong leaf gel extract in the process of healing wounds after tooth extraction. This type of research is a laboratory experiment with a post test only control group approach. The research subjects consisted of 27 jaw preparations of Wistar strain rats which were divided into three types of treatments, namely CMC-Na 1% as negative control, povidone iodine 1% as positive control, and 5% binahong leaf extract gel as treatment. Data analysis was performed using One Way ANOVA test and Post Hoc LSD test. There was a significant difference between the binahong and poviode iodine groups, as well as the binahong and CMC-Na groups with p-value <0.05. The mean difference values between the treatment group and the positive control were -18.267 (day 3), -7.200 (day 5), and -5.733 (day 7). While between the treatment group and the negative control were -11.933 (day 3), -17.533 (day 5), and -13.067 (day 7). 5% concentration of binahong (Anredera cordifolia) leaf extract gel is more effective than CMC-Na and povidone iodine to heal wounds after tooth extraction.
The Differences of Plaque pH between Consumption of Sucrose Chocolate and Stevia Chocolate in Children aged 10-12 Years Saputra, Muhammad Rhaufly Dwi Arga; Kaswindiarti, Septriyani; Murdiyanto, Dendy; Anwaristi, Aprilia Yuanita
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2023: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.4225

Abstract

Introduction: Chocolate is a popular sweet treat among children. The sugar used in chocolate can lead to the development of dental plaque and impact the process of teeth demineralization and remineralization. Until now, there has not been much research on how the acidity of dental plaque differs when children aged 10-12 consume chocolate sweetened with sucrose compared to chocolate sweetened with stevia. This study aims to explore and compare the effects of sucrose chocolate and stevia chocolate on the acidity of dental plaque in children aged 10-12 years. Methods: In this study, the researchers employed quasi-experimental research methods. The research received approval from the Ethical Committee of Health Research at Dr. Moewardi General Hospital, indicated by Ethical Clearance Number 1.884/X/HREC/2023. Initially, on the first day, the researchers measured the plaque pH of twenty-one children aged 10-12 years from SD Muhammadiyah 1 Surakarta. This measurement was done before any intervention by using an excavator on all surfaces of their back teeth – the outer, inner, and in-between surfaces. The researchers combined the collected plaque with 2.5 ml of deionized water in a properly labelled sterile container. The plaque pH was measured using a pH metre (Hanna, Romania), calibrated beforehand with a pH 7 solution. The subjects then consumed 30% sucrose chocolate for 60 seconds. Twenty minutes after this intervention, the researchers measured the plaque pH using the same method. On the second day, the same subjects were instructed to consume 1% stevia chocolate, again using the same method. The results, specifically the average difference in plaque pH before and after the interventions on the two days, were analysed using an independent T-test. Results: The findings revealed that the average plaque pH before eating sucrose chocolate was 6.6222 ± 0.13137, and after consumption, it decreased to 6.2794 ± 0.11425. Before consuming stevia chocolate, the average plaque pH was 6.6746 ± 0.13536, and after consumption, it decreased to 6.4794 ± 0.13059. The average difference in plaque pH before and after consuming sucrose chocolate was 0.3429 ± 0.08508, whereas for stevia, it was 0.1952 ± 0.08517. According to the independent t-test, there was a notable difference in plaque pH between children aged 10-12 years who consumed sucrose chocolate and those who consumed stevia chocolate (p<0.05). Conclusion: Based on the findings from the study comparing the plaque pH in 10-12-year-old children after consuming sucrose chocolate and stevia chocolate, it can be concluded that there is indeed a disparity in plaque pH between the two types of chocolate. Specifically, the plaque pH in children who consumed sucrose chocolate was lower than that in those who consumed stevia chocolate.
Empowering Communities Through Capacity Building Dental And Oral Health Screening And Counseling In Kedungwinong Yuanita Anwaristi, Aprilia; Cahyani
Journal of Community Capacity Empowerment Vol 2 No 2 (2024): Agustus 2024
Publisher : Universitas Tunas Pembangunan Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36728/jcce.v2i2.3771

Abstract

The main issue for the elderly is the loss and damage of many teeth, leading to difficulties in chewing food. The most common cause of tooth loss is poor oral health, particularly dental caries and periodontitis. Elderly individuals often neglect oral hygiene and frequently complain of dental issues such as loose teeth, cavities, or swollen gums. The purpose of empowering communities through capacity building was to increase awareness of the importance of maintaining overall health, dental and oral health, and to assess the level of knowledge and the status of dental and oral health among the residents of Kedung Winong. The proposed solution to the problem is to increase residents' awareness of maintaining dental and oral health, enhance their knowledge of proper tooth brushing techniques, promote the habit of brushing teeth at appropriate times, and raise awareness about the importance of regular health check-ups as a preventive measure against chronic diseases. Methods of oral health counseling and examinations was chosen to solve the problems. The counseling and examination activities for the community in the Muhammadiyah and Aisyiyah branches in Kedungwinong, Nguter, Sukoharjo, were successfully implemented, with enthusiastic and cooperative participation. The activities effectively raised awareness about the importance of dental and oral health.
Effect of coenzyme-q10 in the post-curettage against probing depth, relative attachment loss, and bleeding on probing Aprilia Yuanita ANWARİSTİ
Journal of Syiah Kuala Dentistry Society Vol 5, No 2 (2020): December 2020
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v5i2.20015

Abstract

The mechanical approach is one of the methods for periodontal disease treatment. Besides, medicine also was administered locally to reduce the number of pathogens present in the pocket. Coenzyme Q10 gel has low toxicity, biodegradable, prolongs drug release, and can accelerate tissue healing. The curettage action aims to establish adhesion intensity and remove calculus, bacteria, and granulation tissue. This study aimed to evaluate the effect of coenzyme Q10 gel on chronic periodontitis with curettage in relation to the probing depth (PD), relative attachment level (RAL) and bleeding on probing (BOP). The study sample consisted of 10 patients with curettage treatment and coenzyme Q10 gel application. The gel was applied to the pocket of chronic periodontitis patients after curettage. PD, RAL, and BOP of patients measured before and on days 21 and 30 after gel application. The results showed that there was a significant difference in BOP between observation times. There are differences in the reduction of PD and RAL. Coenzyme Q10 gel's application affected decreasing probing depth, relative attachment loss, and bleeding on probing after curettage
CORRELATION BETWEEN POLYMORPHONUKLEAR (PMN) LEUKOCYTE LEVELS AND GINGIVITIS IN THE UMS SECURITY UNIT Karyadi, Edi; Anwaristi, Aprilia Yuanita; Runting, Nina; Widianti, Marinda
B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah Vol 12, No 1 (2025): Vol 12 No 1 (Juni 2025)
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/jbd.v12i1.1854

Abstract

Gingivitis is a periodontal disease that is often found in the oral cavity. According to Health Research in 2018, the prevalence of gingivitis in Indonesia is ranked second which shows a figure of 96.58%.  The causes of gingivitis are grouped into local factors and systemic factors. Local factors include caries, failed restorations, and piles of food waste, while systemic factors include nutritional, hormonal, and hematology. An abnormal hematological condition that can cause gingivitis is increased polymorphonuclear leukocyte levels in the blood circulation. Polymorphonuclear leukocyte levels can be affected by a person's sleep quality, poor sleep quality can trigger an increase in leukocyte levels. Poor sleep quality is vulnerable to being experienced by shift workers, including the security unit (security guard). This study aims to determine the correlation between polymorphonuclear leukocyte levels and gingivitis in the Universitas Muhammadiyah Surakarta (UMS) security unit. This study uses an observational type of analysis with a cross-sectional approach. The sampling technique uses non-probability sampling in the form of purposive sampling. The sample used was 30 UMS security guards. The data were analyzed using the Chi-Square non-parametric statistical test. The data of this study was obtained from the results of an examination of polymorphonuclear leukocyte levels and gingivitis examination in the form of a gingival index of respondents conducted at RSGM Soelastri Surakarta. The instruments used are diagnostic sets and hematology analyzers. The results of this analysis test obtained a significant value with a value of p=0.035. Conclusion of this study There is a relationship between
Feasibility Study of Rice Farming Investment Using Adol Oyodan Land Rental System Anggara, Muhammad Fariskan; Mahananto; Prasetyo, Agung; Anwaristi, Aprilia Yuanita
Journal of Rural and Urban Community Studies Vol 3 No 2 (2025): August 2025
Publisher : Agribusiness Department, Agriculture Faculty, Tunas Pembangunan University, Surakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36728/jrucs.v3i2.5204

Abstract

This study aims to find out the agricultural land lease system for farmers in Ketaon Village, Banyudono District, Boyolali Regency, and to determine the feasibility of rice farming in the land lease system in Ketaon Village, Banyudono District, Boyolali Regency. The location of the research was carried out in Ketaon Village, Banyudono District, Boyolali Regency. Sampling was carried out using purposive sampling. This research was carried out within 5 planting seasons because in 2 years it consisted of 6 planting seasons; 1 planting season could not be done because there was an improvement in irrigation. The analysis method used is quantitative descriptive. The data analysis used is descriptive analysis and investment analysis. The result of this study is that the agricultural land rental system carried out by the average farmer in Ketaon Village, Banyudono District, Boyolali Regency, is with the adol oyodan land rental system. This rental system is a land rental system where tenants give money in advance directly to the owner of agricultural land (rice fields). This land lease system is worth continuing to strive for this because based on the calculations that have been carried out, it shows from several calculations both through the calculation of NPV (Net Present Value) 20.814.535, IRR (Internal Rate of Return) 100%+, Net Benefit Cost Ratio 3,4779, Gross Benefit Cost Ratio (Gross B/C)2,2033 shows a positive value and meets the eligibility requirements for the farming business carried out.
Kuretase Gingiva untuk Manajemen Perawatan Pasien Periodontitis Kronis Localized Stage II Grade A dengan Hipertensi Stage I : Laporan Kasus Auci Filliandari; Aprilia Yuanita Anwaristi
Quantum Wellness : Jurnal Ilmu Kesehatan Vol. 2 No. 3 (2025): September : Quantum Wellness : Jurnal Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/quwell.v2i3.2272

Abstract

Introduction: Periodontitis treatment depends on the severity of the disease, pocket depth, and bone damage. It consists of (1) emergency phase, (2) non-surgical phase, (3) surgical phase, and (4) maintenance or restorative phase. Each phase plays a crucial role in ensuring healing and controlling periodontitis. The non-surgical phase involves scaling and root planing to remove plaque and tartar, while the surgical phase addresses bone damage and pocket reduction. The maintenance phase is critical to preventing disease recurrence. Objective: The purpose of this case report is to demonstrate the success of curettage in a patient with chronic localized periodontitis stage II grade A and stage I hypertension, within a two-week post-treatment period. Case: A 52-year-old female patient presented at RSGM Soelastri with complaints of bleeding gums during tooth brushing. The patient reported gum bleeding around the lower front teeth for the past six months, without any pain. She was regularly taking antihypertensive medication (amlodipine). Examination revealed deep periodontal pockets in teeth 41 and 42, accompanied by gum swelling, indicating chronic localized periodontitis stage II grade A. The patient also had a history of stage I hypertension, which required careful management during treatment. Conclusion: The treatment for chronic localized periodontitis stage II grade A on teeth 41 and 42 with stage I hypertension was curettage. After two weeks of treatment, the patient showed significant improvement, including reduced bleeding and a decrease in pocket depth, with stable hypertension control. Curettage proved effective in managing the condition, with careful consideration of the patient's hypertension risk factors.