Hospitals are health service institutions that have a central role in providing medical services to the community. The quality of service provided by hospitals greatly determines the level of patient satisfaction. Patient satisfaction is not only influenced by the results of treatment, but also by various other aspects such as the friendliness of medical personnel, speed of service, comfort of facilities, a sense of empathy by medical personnel, the use of health insurance and ease of administration. The purpose of this study is to find out how much health insurance and empathy affect outpatient satisfaction in hospitals. This study is a meta-analysis research with article search conducted based on the feasibility criteria of the PICO model, including: P = Outpatient; I= Health and empathy insurance; C= No health insurance and no empathy; O= Patient satisfaction. Articles were collected from Google Scholar, PubMed and Science Direct. Keywords use "Health insurance" AND "empathy" AND "patient satisfaction" AND "outpatient" AND "Cross-sectional" AND "Multivariate" OR "Adjusted Odds Ratio". The study used 7 selected cross-sectional studies for meta-analysis, with 4,517 respondents indicating that patients with health insurance were 2.27 times more likely to feel satisfied than patients without health insurance. (aOR= 2.27; CI 95%= 1.24 to 4.14; p< 0.02), and patients who had a sense of empathy were 3.41 times more likely to feel satisfaction than patients who did not have a sense of empathy (aOR= 3.41; CI 95%= 2.33 to 4.98; p< 0.52). The conclusion is that health insurance and Empathy can improve outpatient satisfaction in Hospitals. The keywords used were Health Insurance, Empathy, Patient Satisfaction, Outpatients, and Hospitals.