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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Politik dan Pemerintahan Daerah MEDIC MEdical Dedication Electronic Journal Scientific of Environmental Health And Diseases Journal of Medical Studies
Mulyadi, Deri
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Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Journal of Medical Studies

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Gambaran Mikroskopik pada Hepar Tikus Putih Setelah Pemberian Madu sebagai Anti Adhesi Pasca Laparotomi Af, Intan Fatayat; Miftahurrahmah, Miftahurrahmah; Mulyadi, Deri
Journal of Medical Studies Vol. 3 No. 2 (2023): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v3i2.27369

Abstract

ABSTRACT Background: Honey contains heterogeneous substances that inhibit the growth of gram-positive and gram-negative bacteria. It has an anti-inflammatory effect and enhances the healing process after peritoneal damage. Honey, given intraperitoneally, as much as 34% will be absorbed into the systemic circulation and metabolized by the liver. Methods: Paraffin blocks of rat liver organs weighing 200 grams were divided into four groups. Group A was the control group; Group B was given 3 ml of NaCl; Group C was given 0.27 ml of honey intraperitoneally; and Group D was given 0.54 ml of honey intraperitoneally. Histological examination of liver preparations with 40x and 100x magnification microscope. Results: The study showed changes in cell structure in the form of bleeding, portal inflammation, inface hepatitis, lobular inflammation and vacuolization in all treatment groups. Conclusion: Damage to hepatocyte cells in the form of bleeding, portal inflammation, inface hepatitis, lobular inflammation and vacuolization with observations of all fields of view was found in all treatments, namely giving honey at a dose of 0.27 ml, 0.54 ml honey, given 0.9% NaCl 3 ml and the control group. Keywords: Honey, Liver, Anti adhesi ABSTRAK Latar Belakang: Madu mengandung zat heterogen menghambat tumbuhnya bakteri gram positif dan gram negatif, memiliki efek antiinflamasi, dan meningkatkan proses penyembuhan setelah kerusakan peritoneal. Madu yang diberikan secara intraperitoneal, sebanyak 34% akan diserap ke dalam sirkulasi sistemik dan dimetabolisme oleh hepar. Metode: Blok paraffin organ hepar tikus dengan berat 200 gram yang dibagi 4 kelompok. Kelompok A kelompok kontrol, kelompok B diberikan NaCl 3 ml, kelompok C diberikan madu 0,27 ml intraperitoneal, kelompok D diberikan madu 0,54 ml intraperitoneal. Pemeriksaan histologi preparat hepar dengan mikroskop pembesaran 40x dan 100x. Hasil: Hasil dari penelitian terdapat perubahan struktur sel berupa perdarahan ,portal inflamasi, inface hepatitis, lobular inflamasi dan vakuolisasi pada semua kelompok perlakuan. Kesimpulan: Kerusakan sel hepatosit berupa perdarahan, portal inflamasi , inface hepatitis, lobular inflamasi dan vakuolisasi dengan pengamatan seluruh lapangan pandang didapatkan pada semua perlakuan yaitu pemberian madu dosis 0,27ml ,madu 0,54ml, diberikan NaCl 0,9% 3 ml dan kelompok kontrol. Kata Kunci: Madu, Hepar, Anti adhesion
Gambaran Karakteristik Pasien Retinopati Hipertensi di Poli Mata RSUD H. Abdul Manap Kota Jambi Periode Tahun 2015-2021 Sari, Wintan; Riasari, Vonna; Mulyadi, Deri
Journal of Medical Studies Vol. 3 No. 2 (2023): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v3i2.27373

Abstract

ABSTRACT Background: Hypertensive retinopathy is a condition with changes in retinal vascularity in a population suffering from hypertension and one of the earliest target organ damage in hypertension, so the condition of the retinal blood vessels is often used as a measure of the condition of the blood vessels of other organs of the body. The purpose of this study was to determine the characteristics of hypertensive retinopathy patients at RSUD H. Abdul Manap kota jambi. Methods: This research uses a descriptive observational method with a cross-sectional research design. The sample for this study was medical record data of hypertensive retinopathy patients at the eye clinic at RSUD H. Abdul Manap Kota Jambi. The variables in this study were age, sex, degree of hypertension, length of time suffering from hypertension, and body mass index. The total number of samples is 32 people. Results: Based on age, the highest category was found at the age of 51-50 years, with 15 people (46.%). Based on gender sex, the most categories were men, namely 20 people (62.5%). Based on the degree of hypertension, the highest category was grade 1 hypertension, namely 19 people (59.4%). Based on the duration of suffering from hypertension, the highest category was found in the <5 years group, namely 19 people (59.4%). Based on body mass index, the highest category was found in the obesity group 1, namely 14 people (43.8%). Conclusion: Most characteristics of hypertensive retinopathy patients based on age were 51-50 years old, based on sex the most were male, based on the degree of hypertension the most were grade 1 hypertension, based on the duration of suffering from hypertension the most is <5 years, based on the highest body mass index is obesity 1. Key words: Hypertensive retinopathy, Patient characteristics ABSTRAK Latar Belakang: Retinopati hipertensi merupakan suatu kondisi dengan perubahan vaskularisasi retina pada populasi yang menderita hipertensi dan salah satu kerusakan organ target paling awal pada hipertensi, sehingga keadaan pembuluh darah retina sering dipakai sebagai ukuran keadaan pembuluh darah organ tubuh lain. Tujuan penelitian ini adalah untuk mengetahui karakteristik pasien retinopati hipertensi di RSUD H. Apdul Manap. Metode: Peneitian ini menggunakan metode deskriptif observasional dengan desain penelitian cross-sectional. Sampel peneitian ini adalah data rekam medis pasien retinopati hipertensi di poli mata RSUD H. Abdul Manap Kota Jambi. Variabel peneitian ini adalah usia, jenis kelamin, derajat hipertensi, lamanya menderita hipertensi, dan indek masa tubuh. Jumlah total sampel adalah 32 orang. Hasil: Berdasarkan usia di dapatkan kategori terbanyak pada umur 51 – 50 tahun sebanyak 15 orang (46,%). Berdasarkan jenis kelamin di dapatkan kategori terbanyak adalah laki-laki yaitu sebanyak 20 orang (62,5%). Berdasarkan derajat hipertensi di dapatkan kategori terbanyak adalah hipertensi derajat 1 yaitu sebanyak 19 orang (59,4%). Berdasarkan lamanya menderita hipertensi di dapatkan kategori terbanyak pada kelompok < 5 tahun yaitu sebanyak 19 orang (59,4%). Berdasarkan indek masa tubuh di dapatkan kategori terbanyak pada kelompok obesitas 1 yaitu sebanyak 14 orang (43,8%). Kesimpulan: Karakteristik pasien retinopati hipertensi terbanyak berdasarkan usia adalah umur 51- 50 tahun, berdasarkan jenis kelamin terbanyak adalah laki-laki, berdasarkan derajat hipertensi terbanyak adalah hipertensi derajat 1, berdasarkan lamanya menderita hipertensi terbanyak adalah <5 tahun, berdasarkan indeks masa tubuh terbanyak adalah obesitas 1. Kata Kunci: Retinopati hipertensi, Karakteristik pasien
Co-Authors Af, Intan Fatayat Armaidi Darmawan Epriadi, Dedi Erny Kusdiyah Harahap, Asro Hayani Herlambang Humaryanto Humaryanto, Humaryanto Husnul, Husnul Ima Maria Iskandar, Mirna Marhami Jaya, Mulia Justitia, Budi Miftahurrahmah Miftahurrahmah, Miftahurrahmah Moniga, Agra Farellio Nuriyah, Nuriyah Patrick William Gading Raharja, Ifan Fauzany Riasari, Vonna Sari, Wintan Simanjuntak, Patrick William Gading Wahyu Indah Dewi Aurora