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Herpes Zoster Lumbalis Sinistra pada Pasien Terinfeksi HIV Hastuti, Rini; Ulya, Imroatul; Mustifah, Etty Farida; Risman, Muhammad; Dharmawan, Nugrohoaji
Cermin Dunia Kedokteran Vol 45, No 4 (2018): Cidera Kepala
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.005 KB) | DOI: 10.55175/cdk.v45i4.667

Abstract

Human Immunodeficiency Virus (HIV) merupakan virus yang menyebabkan menurunnya sistem kekebalan tubuh. Diketahui ada hubungan antara infeksi HIV dengan berbagai manifestasi penyakit kulit. Herpes zoster merupakan penyakit kulit yang disebabkan reaktivasi dan multiplikasi virus varicella zoster yang menetap pada ganglia sensoris setelah varicella. Kasus Laki-laki usia 32 tahun dengan gelembung bergerombol berisi air dengan dasar kulit eritem disertai nyeri pada betis sampai punggung kaki kiri sejak 3 hari. Pasien terinfeksi HIV sejak 7 bulan. Didapatkan lesi vesikel herpetiformis di atas dasar eritem sesuai dermatom Lumbal 5 (L5) sinistra. Tes Tzank menunjukkan adanya sel raksasa berinti banyak. Jumlah sel CD4 212/μL.Human Immunodeficiency Virus (HIV) may suppress the immune system. There is a relationship between HIV infection with various skin manifestations. Herpes zoster is caused by reactivation and multiplication of varicella zoster virus in sensory ganglia after varicella. Case : A 32 year-old male with painful, clustered vesicle on erythematous base along left calf to foot since 3 days. He was diagnosed HIV positive 7 months ago. Physical examination showed herpetiform vesicles on erythematous base in left Lumbal 5 (L5) dermatome. Tzank test showed the presence of multinucleated giant cells. CD4 cell count is 212/μL.
Diagnosis Luka Tungkai Kronis Rafika Paramitasari, Anggana; Risman, Muhammad; Rahman, Aulia; Rieka Sulaikha, Khalida; Kariosentono, Harijono; Mulianto, Nurrachmat
Cermin Dunia Kedokteran Vol 46, No 1 (2019): Obstetri - Ginekologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1096.883 KB) | DOI: 10.55175/cdk.v46i1.534

Abstract

Luka kronis adalah luka yang tidak dapat mengalami proses penyembuhan luka sesuai urutan dan dalam rentang waktu normal. Mayoritas luka kronis didapatkan di ekstremitas inferior dengan penyebab antara lain insufisiensi vena (45-60%), insufisiensi arteri (10-20%), diabetes (15-25%), ulkus dekubitus (1-5%), dan lain-lain (10-15%). Masing-masing penyebab memberikan gambaran klinis berbeda, begitu pula terapinya. Oleh karena itu gambaran klinis, patogenesis, dan diagnosis banding penting diketahui.Chronic wounds are characterized by failure to progress through a proper timely sequence of wound repair or without restoring to normal anatomy and function. Chronic wounds in lower leg including foot is a condition caused by venous insufficiency (45-60%), artery insufficiency (10-20%,) diabetes mellitus (15-25%), decubitus ulcer (1-5%), or other causes (10-15%). Each etiology has different clinical manifestations and therapy. Treatment of leg ulcers needs evaluation of many different etiologies. 
Double-blind randomized trials once a week narrowband ultraviolet B (NB-UVB) phototherapy in vitiligo Utami, Retno Dwi; Murti, Mira Trisna; Risman, Muhammad; Kusumawardhani, Arie
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 3
Publisher : UI Scholars Hub

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Abstract

Background: Vitiligo is a skin pigmentation disorder, affecting approximately 1-2% population worldwide. Currently, there are wide varieties of treatment to achieve re-pigmentation, and phototherapy is one of the effective treatments. Narrowband ultraviolet B (NB-UVB) is administered twice a week according to the phototherapy protocol for vitiligo. Some vitiligo patients have difficulty following this schedule, leading to decrease of patient’s compliance. Therefore, we performed study comparing the efficacy of phototherapy frequency, once a week and twice a week NB-UVB in vitiligo. Methods: This preliminary study divided 10 patients into 2 groups of 5 patients each with randomized, double-blind method. Group A was scheduled for NB-UVB phototherapy twice a week while Group B was scheduled for once a week. All patients received topical desoxymetasone cream once daily. Re-pigmentation were compared using Vitiligo Area Scoring Index (VASI). VASI was graded as good (≥25%), moderate (10-24%), and poor (<10 %) responses. Evaluation for melanin index for each lesion was assessed by Mexameter® and cumulative doses of phototherapy were compared. Results: Thirty-seven lesions were treated on face and neck, trunk and extremities. Good responses were obtained in 14.29% group A patients and 13.04% group B patients. The mean of cumulative doses phototherapy in group A was 850 mJ/cm2, whereas group B was 800 mJ/cm2. There was no significant differences (p>0.05) between both groups in terms of re-pigmentation, cumulative doses of phototherapy, and melanin index. Conclusion: In vitiligo, once a week NB-UVB phototherapy appears to be as efficacious as twice a week treatment schedule.
The effect of face washing frequency on acne vulgaris patients Hastuti, Rini; Mustifah, Etty Farida; Ulya, Imroatul; Risman, Muhammad; Mawardi, Prasetyadi
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 3, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Patients with acne often wash their faces twice a day, but there are not many studies supporting this practice. Methods: A single-blind randomized clinical trial was conducted in 38 subjects, divided into three groups based on face washing frequency (once, twice, and thrice a day). All groups used the same cleanser. The acne vulgaris severity and the number of lesions were assessed prior to study. After eight weeks, we re-assessed the acne severity, the number of lesions, the adverse event and patient’s self-evaluation. SPSS 17 was used to analyze the face washing frequency and the number of acne lesions. Results: Reduction in the average number of acne lesions was found in once and twice face washing groups, while the thrice group had increased number of acne lesions. The frequency of face washing with the number of lesions provided significant result in group 1, but it only reduced the number of comedones (p value = 0.041). Conclusion: Acne patients with only comedones lesions can be advised to wash their faces once a day.
The Implementation of ELLLO Web-Based Application in Teaching Listening at MA Al-Ikhlas Ujung Bone Jabu, Baso; Risman, Muhammad; Nur, Sahril
Celebes Journal of Language Studies Vol. 4 No. 1 June 2024
Publisher : Har Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51629/cjls.v4i1.181

Abstract

This research aims to define the use of the ELLLO web-based application in teaching listening at MA Al-Ikhlas Ujung Bone. This study was a case study that would draw a description towards the phenomenon in the field. The participants were an English teacher and the students in XII grade of MA Al-Ikhlas Ujung Bone. The research instruments employed were observation and interview. The data were collected using observation techniques including observation checklist, note-taking, collected data from teachers’ documents, and interview techniques with the teacher and students. The result of the data analysis, shows that, the teacher used and took into consideration that using the media is helpful, still it needs to look forward to the supports and hindrances that can appear particularly on ELLLO that contains video, audio, material, level and quiz. The teacher faced supports and hindrances on using ELLLO in teaching listening in the class. The supports show that the media is very helpful in teaching and practicing students’ listening to improve students’ listening skill. However, the hindrance of using the media shows that the students in the learning process need to be shadowed to anticipate students’ irrelevant activity.
PERBANDINGAN EFEKTIVITAS EKSTRAK DAUN BANDOTAN (Ageratum conyzoides Linnaeus) DAN EKSTRAK DAUN SINTRONG (Crassocephalum crepidioides) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus ATCC 6538 Andiri, Mochammad; Mulyaningsih, Ruri Eka Maryam; Naldi, Yandri; Wahdini, Maya; Risman, Muhammad; Afifah, Helga Marwa
Tunas Medika Jurnal Kedokteran & Kesehatan Vol 11 No 1 (2025): TUNAS MEDIKA JURNAL KEDOKTERAN & KESEHATAN
Publisher : Tunas Medika Jurnal Kedokteran & Kesehatan

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Abstract

Latar Belakang Staphylococcus aureus merupakan penyebab infeksi dan kematian bayi di Indonesia, terutama pneumonia. Menurut data Kementerian Kesehatan Republik Indonesia Tahun 2022, kematian akibat pneumonia ditemukan 14,4% kasus pada bayi dan 9,4% kasus pada balita dengan 1.475 kasus berada di Kota Cirebon. Reaksi alergi akibat antibiotik menjadi masalah serius dalam pengobatan, sehingga diperlukan alternatif bahan alami seperti daun bandotan (Ageratum conyzoides Linnaeus) dan daun sintrong (Crassocephalum crepidioides). Kandungan senyawa alkaloid, flavonoid, saponin, dan tanin pada daun bandotan (Ageratum conyzoides Linnaeus) dan daun sintrong (Crassocephalum crepidioides) diduga efektif menghambat pertumbuhan bakteri. Tujuan Mengetahui perbandingan efektivitas ekstrak daun bandotan (Ageratum conyzoides Linnaeus) dan ekstrak daun sintrong (Crassocephalum crepidioides) terhadap pertumbuhan bakteri Staphylococcus aureus. Metode Penelitian eksperimen dengan rancangan posttest only control group design dan dilakukan dari bulan April-Juli 2023. Penelitian ini menggunakan 8 kelompok perlakuan berupa ekstrak daun bandotan (Ageratum conyzoides Linnaeus) dan ekstrak daun sintrong (Crassocephalum crepidioides) dengan konsentrasi uji 50%, 75%, dan 100% serta kloramfenikol (kontrol positif) dan DMSO 10% (kontrol negatif). Data dianalisis menggunakan uji One-way Anova, Post-hoc Tukey HSD, dan uji T Independent. Hasil Terdapat perbandingan efektivitas ekstrak daun bandotan (Ageratum conyzoides Linnaeus) dan ekstrak daun sintrong (Crassocephalum crepidioides) terhadap pertumbuhan bakteri Staphylococcus aureus. Ekstrak daun sintrong (Crassocephalum crepidioides) memiliki efektifvitas rata-rata daya hambat ± 10,44083 mm (P value 0,000). Kesimpulan Kelompok ekstrak daun sintrong (Crassocephalum crepidioides) adalah kelompok yang paling efektif menghambat pertumbuhan bakteri Staphylococcus aureus. Background Staphylococcus aureus is a leading cause of infections and infant mortality in Indonesia, especially pneumonia. According to data from the Indonesian Ministry of Health in 2022, pneumonia accounted for 14.4% of cases in infants and 9.4% in toddlers, with 1,475 cases reported in Cirebon city. Allergic reactions from antibiotics have become a serious issue in treatment, prompting the need for natural alternatives such as bandotan leaf (Ageratum conyzoides Linnaeus) and sintrong leaf (Crassocephalum crepidioides). The compounds alkaloids, flavonoids, saponins, and tannins present in these leaves are believed to effectively inhibit bacterial growth. Aim To compare the effectiveness of bandotan leaf extract (Ageratum conyzoides Linnaeus) and sintrong leaf extract (Crassocephalum crepidioides) on the growth of Staphylococcus aureus bacteria. Method Experimental research with posttest-only control group design from April to July 2023. The study used 8 groups consisting of bandotan leaf extract (Ageratum conyzoides Linnaeus) and sintrong leaf extract (Crassocephalum crepidioides) at concentrations 50%, 75%, and 100%, as well as chloramphenicol (positive control) and DMSO 10% (negative control). Data were analyzed using One-way ANOVA, Post-hoc Tukey HSD, and Independent T-test. Results There is a comparison of the effectiveness of bandotan leaf extract (Ageratum conyzoides Linnaeus) and sintrong leaf extract (Crassocephalum crepidioides) against the growth of Staphylococcus aureus bacteria. Sintrong leaf extract (Crassocephalum crepidioides) exhibits an average inhibitory zone effectiveness of ± 10.44083 mm (P-value 0.000). Conclusion The Crassocephalum crepidioides extract group was the most effective in inhibiting the growth of Staphylococcus aureus bacteria.
The Influence of Internal Factors on the Success of Leprosy Treatment at Cibuaya Health Center, Indonesia Sari, Anggi Novita; Risman, Muhammad; Affandi, Thysa Thysmelia
GHMJ (Global Health Management Journal) Vol. 8 No. 2s (2025): Special Issues
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-82s1238

Abstract

Background: Indonesia still has a significant number of leprosy cases; there was an increase in cases to 12,441 compared to the previous year, which was 10,976 (WHO, 2023). At the national level, the target percentage of leprosy treatment has not been reached; 87% achievement was obtained, while the national indicator target is 90%. Age, gender, marital status, education level, occupation, and leprosy type are among the internal characteristics that contribute to the effectiveness of leprosy therapy. The most leprosy cases in Karawang Regency are found in Cibuaya Health Center, Indonesia. Aims: This study aims to determine the influence of internal factors (age, gender, marital status, education, occupation, and leprosy type) on the success of leprosy treatment at the Cibuaya Health Center. Methods: Observational analysis with cross-sectional design was used in this study with a sample size of 110 respondents at the Cibuaya Health Center. Medical records from patients receiving leprosy treatment at the Cibuaya Health Center served as the sample. Total sampling, a non-probability sampling technique, has been used. The study was conducted in June 2024. Results: Leprosy treatment success was found to be influenced by age (p=0.09), gender (p=0.001), marital status (p=0.012), education level (p=0.001), and leprosy type (p=0.001) in the bivariate analysis using the Chi-square test. However, the occupation factor did not show a significant effect on treatment success (p=0.275). Based on multivariate logistic regression analysis, Leprosy type was the most dominant factor influencing treatment success (Exp(B) = 38.863). The limitation of this study is that it did not investigate internal factors in the success of leprosy treatment by using laboratory results (such as BTA testing) after treatment. Conclusion: The success of leprosy treatment at the Cibuaya Health Center is influenced by age, gender, marital status, education level, and leprosy type. The most influential factor on the success of leprosy treatment is the type of leprosy. However, the occupation factor did not show a significant effect on treatment success. These findings can inform targeted strategies to improve treatment outcomes, especially among high-risk groups such as Multibacillary (MB) patients and the elderly.