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All Journal Cermin Dunia Kedokteran Journal of General Procedural Dermatology and Venereology Indonesia Sanus Medical Journal
Mustifah, Etty Farida
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Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Herpes Zoster Lumbalis Sinistra pada Pasien Terinfeksi HIV Hastuti, Rini; Ulya, Imroatul; Mustifah, Etty Farida; Risman, Muhammad; Dharmawan, Nugrohoaji
Cermin Dunia Kedokteran Vol 45, No 4 (2018): Cidera Kepala
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.005 KB) | DOI: 10.55175/cdk.v45i4.667

Abstract

Human Immunodeficiency Virus (HIV) merupakan virus yang menyebabkan menurunnya sistem kekebalan tubuh. Diketahui ada hubungan antara infeksi HIV dengan berbagai manifestasi penyakit kulit. Herpes zoster merupakan penyakit kulit yang disebabkan reaktivasi dan multiplikasi virus varicella zoster yang menetap pada ganglia sensoris setelah varicella. Kasus Laki-laki usia 32 tahun dengan gelembung bergerombol berisi air dengan dasar kulit eritem disertai nyeri pada betis sampai punggung kaki kiri sejak 3 hari. Pasien terinfeksi HIV sejak 7 bulan. Didapatkan lesi vesikel herpetiformis di atas dasar eritem sesuai dermatom Lumbal 5 (L5) sinistra. Tes Tzank menunjukkan adanya sel raksasa berinti banyak. Jumlah sel CD4 212/μL.Human Immunodeficiency Virus (HIV) may suppress the immune system. There is a relationship between HIV infection with various skin manifestations. Herpes zoster is caused by reactivation and multiplication of varicella zoster virus in sensory ganglia after varicella. Case : A 32 year-old male with painful, clustered vesicle on erythematous base along left calf to foot since 3 days. He was diagnosed HIV positive 7 months ago. Physical examination showed herpetiform vesicles on erythematous base in left Lumbal 5 (L5) dermatome. Tzank test showed the presence of multinucleated giant cells. CD4 cell count is 212/μL.
Perbandingan Fungsi Barier Kulit Pasien Dermatitis Atopik oleh Krim Aloe Vera dan Krim Seramid: Penelitian Awal Mustifah, Etty Farida; Dewi, Susanti Rosmala; Hastuti, Rini; Kariosentono, Harijono
Cermin Dunia Kedokteran Vol 45, No 8 (2018): Alopesia
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (879.926 KB) | DOI: 10.55175/cdk.v45i8.621

Abstract

Latar Belakang: Dermatitis atopik (DA) adalah penyakit peradangan kulit kronik, residif, ditandai rasa gatal dan berhubungan dengan riwayat atopi. Penggunaan pelembap teratur merupakan kunci utama tatalaksana DA. Tujuan: Membandingkan efektivitas krim seramid dan aloe vera sebagai barrier pada pasien DA dengan mengukur nilai TEWL baseline dan setelah 2 minggu pemberian. Hasil: Rerata TEWL terendah pada krim A (aloe vera) dan B (seramid) terjadi pada minggu ke-2 (7,39 + 3,17 vs 6,55 + 3,25). Skor TEWL turun dari sebelum diolesi krim (baseline), pada minggu ke-0, ke-1, ke-2, dan pada minggu ke-3 meningkat kembali setelah tidak menggunakan krim (p=0,005). Secara umum skor TEWL pada pengolesan krim B lebih rendah dari krim A, namun perbedaan tersebut tidak bermakna (p=0,512). Simpulan: Pada penelitian ini tidak didapatkan perbedaan bermakna nilai TEWL setelah penggunaan krim aloe vera dan krim seramid, sehingga disimpulkan efektivitasnya sama.Background: Atopic dermatitis (DA) is a chronic skin inflammatory disease, residif, characterized by itching and associated with atopy history. Regular use of moisturizers is the key of DA management. Objective: Compare the effectiveness of seramid and aloe vera creams as a barrier in DA patients by measuring baseline TEWL values and after 2 weeks of using. Results: The lowest mean TEWL in cream A (aloe vera) and B (seramid) occurred at week 2 (7.39 + 3.17 vs 6.55 + 3.25). TEWL scores decrease from before smearing the cream (baseline), at week 0, 1, 2, and at week 3 increase again after no cream (p = 0.005). In general, the TEWL score on cream B treatment was lower than cream A, but the difference was not significant (p = 0,512). Conclusion: There is no significant difference in TEWL value after the use of aloe vera cream and ceramic cream, so it is concluded that the effectiveness is the same. 
Metotreksat Intramuskular untuk Terapi Psoriasis Vulgaris: Serial Kasus Rafika Paramitasari, Anggana; Hartati, Agung Triana; Mustifah, Etty Farida; Yustin Ellista Sari, Endra; Kusumawardani, Arie
Cermin Dunia Kedokteran Vol 45, No 8 (2018): Alopesia
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (821.515 KB) | DOI: 10.55175/cdk.v45i8.627

Abstract

Metotreksat merupakan pilihan terapi psoriasis yang efektif. Laporan pemberian MTX parenteral pada psoriasis vulgaris masih jarang. Kami melaporkan 8 kasus psoriasis vulgaris dengan terapi injeksi MTX dosis inisial 10mg/minggu dan dinaikkan menjadi 15mg/minggu. Dalam evaluasi 8-12 minggu, terdapat perbaikan klinis yang dievaluasi menggunakan Psoriasis Activity and Severity Index (PASI), luas Body Surface Area (BSA) dan Dermatology Life Quality Index (DLQI). Bioavailabilitas MTX parenteral lebih baik dibandingkan peroral. Tidak ditemukan efek samping selama pemberian injeksi MTX.Methotrexate (MTX) is the commonly prescribed for psoriasis. Reports on parenteral MTX for psoriasis in Indonesia are still scarce. We reported eight psoriasis patients treated with intramuscular MTX 10mg/week increased to 15mg/week. The clinical improvement was remarkable demonstrated with Body Surface Area (BSA), Psoriasis Activity and Severity Index (PASI) and Dermatology Life Quality Index (DLQI) scores. Bioavailability of parenteral MTX is better than oral MTX. No adverse effect was found and the clinical improvement was good.
The effect of face washing frequency on acne vulgaris patients Hastuti, Rini; Mustifah, Etty Farida; Ulya, Imroatul; Risman, Muhammad; Mawardi, Prasetyadi
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 3, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Patients with acne often wash their faces twice a day, but there are not many studies supporting this practice. Methods: A single-blind randomized clinical trial was conducted in 38 subjects, divided into three groups based on face washing frequency (once, twice, and thrice a day). All groups used the same cleanser. The acne vulgaris severity and the number of lesions were assessed prior to study. After eight weeks, we re-assessed the acne severity, the number of lesions, the adverse event and patient’s self-evaluation. SPSS 17 was used to analyze the face washing frequency and the number of acne lesions. Results: Reduction in the average number of acne lesions was found in once and twice face washing groups, while the thrice group had increased number of acne lesions. The frequency of face washing with the number of lesions provided significant result in group 1, but it only reduced the number of comedones (p value = 0.041). Conclusion: Acne patients with only comedones lesions can be advised to wash their faces once a day.
Analisis Kadar Nrf2 plasma Pada Tikus dengan Defisisensi Vitamin B12 Stujanna, Endin Nokik; Ujianti, Irena; Mustifah, Etty Farida
Sanus Medical Journal Vol. 2 No. 1 (2021)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v1i1.6545

Abstract

Background. Vitamin B12 deficiency is a significant problem, particularly in developing countries. The increasing complexity of the Vitamin B12 molecule, the deficiency condition, causes a complex cell level disorder. The clinical manifestation of vitamin B12 deficiency is anemia, but it is believed that due to the complexity of vitamin B12, there are still other molecular disorders. This study aims to establish the pathway of damage caused by vitamin B12 deficiency in the Nrf2 molecule. Methods. An animal experiment involving 12 male Sprague Dawley rats were randomly divided into control and 16-week treatment. There are two research groups, namely the control group and the treatment group. The control group was given a standard diet, while the treatment group was assigned a vitamin B12 deficiency diet. At the end of treatment, The levels of vitamin B12 in the liver tissue and plasma NRF2 were measured. Statistical Analysis. Nrf2 and vitamin B12 levels were statistically analyzed using the Student's T-test, and the correlation between vitamin B12 and Hb was analyzed using the Spearmen test. Data that cannot use by Independent T-test were tested using the Mann Whitney test. Results/Conclusion. There was no significant difference between the control and treatment groups on plasma Nrf2 levels (4.02 ± 0.59 pg/ml vs 3.34 ± 0.55 pg/ml; p = 0.07) and tissue vitamin B12 (0.0035 ± 0.0016 µg/ml vs 0.0030 ± 0.0006 µg/ml ; p = 0.8). Keywords: Nrf2 Plasma, Defisiensi, Vitamin B12
Enhancing Reproductive Health and Sexually Transmitted Infection Prevention Awareness through Community Engagement Mustifah, Etty Farida; Ujianti, Irena; Sukarya, Wawang Setiawan; Pangestu, Mulyoto
Sanus Medical Journal Vol. 6 No. 2 (2024)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v6i2.18202

Abstract

ntroduction The Thousand Islands, a popular tourist destination in DKI Jakarta Province, is facing a new challenge, namely the increasing concern about the transmission of Sexually Transmitted Infections (STIs) triggered by the increase in tourism visits. In response to this issue, a community service activity was carried out by the Faculty of Medicine at UHAMKA. Objective The aim of this activity is to raise awareness and knowledge in the community, particularly among educators in the Thousand Islands, about the dangers of and prevention against STIs and the importance of Reproductive Health Education. Method The partners in this community service activity are teachers in the Thousand Islands. A total of 30 teachers were involved in this training. The methods used involve training and counseling that incorporate direct training and open discussions. Data were collected through observations and field notes. Results The results of this activity include an increase in understanding and skills of teachers concerning Reproductive Health Education and STI prevention, which they can apply in educating students. Additionally, it was found that community awareness about the dangers of STIs also increased as a direct result of this activity. Conclusion The conclusion that can be derived from this activity is that appropriate education and training on reproductive health and the prevention of STIs for the community, specifically educators, can be an effective strategy in controlling STI transmission in tourist areas like the Thousand Islands. This activity also helps to strengthen the local health system in dealing with the challenge of STI transmission.
Co-Authors Dewi, Susanti Rosmala Dharmawan, Nugrohoaji Hartati, Agung Triana Kariosentono, Harijono Kusumawardani, Arie MULYOTO PANGESTU Prasetyadi Mawardi Rafika Paramitasari, Anggana Rini Hastuti Risman, Muhammad Stujanna, Endin Nokik Sukarya, Wawang Setiawan Ujianti, Irena Ulya, Imroatul Yustin Ellista Sari, Endra