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Body mass index as the most influential factor of high-sensitivity C-reactive protein in non-diabetic adults Mulyamin, Winda; Kurniawan, Liong Boy; Adnan, Endy; Widaningsih, Yuyun; Idris, Irfan; Santoso, Arif; Yustisia, Ika
Universa Medicina Vol. 40 No. 1 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.22-28

Abstract

BACKGROUNDHigh-sensitivity C-reactive protein (hsCRP) has been widely accepted as a predictor of future cardiovascular risk that reflects a microinflammatory state. Obesity linked to microinflammation increases the prevalence of metabolic disorders and cardiovascular diseases. This study aimed to determine the association between several obesity indices namely body mass index (BMI), waist circumference (WC), body fat percentage (fat), and visceral fat (VF) with hsCRP in non-diabetic adults. METHODSThis was a cross-sectional study performed on 80 non-diabetic adults with ages ranging from 20-40 years. The obesity indices BMI, WC, body fat percentage, and VF were measured. We then measured the hsCRP levels using an immunoturbidimetric method. Simple and multiple linear regression tests were used to analyze the association between obesity indices and hsCRP levels. RESULTSMean of log BMI, log WC, and log VF was 1.41 ± 0.08 kg/m2, 1.93 ± 0.06 cm, and 0.95 ± 0.27 units, respectively. Simple linear regression tests showed that log BMI (â=3.506; p<0.001), log WC (â=3.672; p<0.001), log VF (â=0.833; p<0.001), and log systolic blood pressure (â=3.739; p=0.024) had a significant positive correlation with log hsCRP levels. Further multiple linear regression test showed that log BMI (â=3.772; Beta=0.674; p<0.001) had the greater effect on log hsCRP levels compared to other indices. CONCLUSIONS    BMI had a greater influence on hsCRP levels compared to other obesity indices in non-diabetic adults. Body mass index can be used as a better index in predicting hsCRP levels compared to other indices.
The Role of Microbiota on the Incidence of Obesity Azzahra, Jihan; Bamahry, Aryanti R; Adnan, Endy
Journal La Medihealtico Vol. 5 No. 2 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i2.1227

Abstract

Obesity is predicted to become a global public health problem, especially in developing countries. Obesity is characterized by a body mass index (BMI) of 30 or more, which is calculated by dividing a person's weight by the square of their height (in kilograms per square meter). The incidence of obesity by age increased from 4.6% in 1980 to 14.0% in 2019. According to the World Health Organization (WHO), around 2 billion adults are classified as overweight, while another 650 million people are categorized as obese. Based on a national survey, the obesity rate in Indonesia is 23.1%, while in South Sulawesi province it is 31.6% (Riskesdas, 2018). This can alter the gut microbiota structurally and functionally, and the gut microbiota can also modulate nutritional status. A certain abundance and diversity of bacteria may facilitate energy storage and metabolic pathways that lead to obesity. Dietary interventions with probiotics, prebiotics, or synbiotics may be effective in counteracting the disturbances observed in the gut microbiota during obesity or unbalanced diets, as they may be able to reduce and maintain body weight. Intestinal anaerobic bacteria, including Firmicute and bacteroids, can hydrolyze carbohydrates that cannot be digested by the intestine, obtaining short chain fatty acids (SCFA) including acetate, propionate and butyrate, which have an impact on human health. Therefore, anaerobic bacteria can inhibit obesity.
Effectiveness of Chronic Disease Management Program in Lowering Blood Pressure in Hypertensive Patients: Literature Review Akbar, Muhammad Alief; Wahid, Syarifuddin; Lestari, Indah; Adnan, Endy; Indarwati, Rezky Putri
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1606

Abstract

Chronic illnesses are a global health issue that kills people. Hypertension is a blood vessel disorder that compromises the body's tissues' oxygen and nutrient supply. In 2025, 1.5 billion people will have hypertension, and 9.4 million will die from it. This research review evaluates the Chronic Disease Management Program's blood pressure-lowering effects in hypertensive patients. A PRISMA Flow Diagram-based literature review. Downloading scientific papers from PubMed, Portal Garuda, and Google Scholar follows SINTA IV and V criteria. This article searches for Prolanis, blood pressure, and hypertension. Search results yielded 103 articles. Using inclusion criteria, 11 research publications were chosen for review. The study found that the chronic disease management program, which included medical consultations, Prolanis participant education, SMS gateway reminders, home visits, club activities (exercise), and health status monitoring, effectively lowered blood pressure in hypertension patients.
KARAKTERISTIK PASIEN ILEUS OBSTRUKSI DI RUMAH SAKIT IBNU SINA MAKASSAR TAHUN 2019-2021 Muh Muslih Rijal, Andi; Gani, Aziz Beru; Tulak, Pither Sandy; Adnan, Endy; Erida, Berry
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i1.27190

Abstract

Obstruksi usus dapat berupa sumbatan mekanis atau fungsional dari usus halus atau usus besar. Menurut WHO mengatakan bahwa pada tahun 2020 penyakit saluran pencernaan berada dalam 10 besar penyakit mengakibatkan kematian di dunia. Tujuan penelitian ini untuk mengetahui karakteristik pasien Ileus Obstruksi di Rumah Sakit Ibnu Sina. Metode penelitian ini menggunakan desain penelitian deskriptif. Penelitian ini dilakukan di Rumah Sakit Ibnu Sina Makassar, dilakukan pada bulan November 2023. Populasi dalam penelitian ini adalah pasien Ileus Obstruksi Di Rumah Sakit Ibnu Sina Makassar. Sampel dalam penelitian ini adalah pasien Ileus Obstruksi Di Rumah Sakit Ibnu Sina Makassar terhitung sejak tanggal 1 Januari 2019 sampai dengan 31 Desember 2021. Teknik pengambilan sampel menggunakan metode total sampling. Dari hasil penelitian didapatkan kesimpulan bahwa sebagian besar usia pasien Illeus Obstruksi berada pada kategori 46-55 tahun, sebagian besar pasien Illeus Obstruksi berjenis kelamin laki-laki, berdasarkan etiologinya sebagian besar  pasien Illeus Obstruksi diakibatkan oleh adhesi. berdasarkan outcome sebagian besar pasien Illeus Obstruksi memiliki prognosis membaik, berdasarkan tatalaksana definitif sebagian besar pasien Illeus Obstruksi mendapatkan penanganan operatif, berdasarkan lama rawat inap sebagian besar pasien Illeus Obstruksi mendapatkan perawat selama 6-10 hari. Debgan demikian diharapkan penelitian ini dapat mengevaluasi jenis intervensi yang paling efektif dalam mengatasi ileus obstruktif. Evaluasi ini akan membantu dalam menentukan pendekatan pengobatan terbaik untuk pasien dengan ileus obstruktif.
GAMBARAN KADAR PROTEIN URIN DENGAN PASIEN HIPERTENSI : LITERATURE REVIEW Aris, Rismayana; Eka Yanti, Andi Kartini; Adnan, Endy
Jurnal Kesehatan Tambusai Vol. 5 No. 2 (2024): JUNI 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i2.29774

Abstract

Hipertensi merupakan masalah kesehatan utama yang berkontribusi terhadap penyakit kardiovaskular dan komplikasi lainnya. Hubungan pemeriksaan protein urine pada penderita hipertensi adalah salah satu akibat adanya gangguan pada ginjal. Tujuan dari tinjauan literatur ini adalah untuk melihat gambaran kadar protein urin dengan pasien hipertensi. Menggunakan metode literature review dengan prinsip Diagram Alir PRISMA. Artikel atau jurnal ilmiah diunduh dari PubMed, Portal Garuda, dan Google Scholar dengan standar SINTA IV dan V. Kata kunci dalam pencarian artikel ini yaitu gambaran kadar protein urin dengan pasien hipertensi. Didapatkan 146 artikel dalam hasil pencarian. Semua artikel diseleksi berdasarkan kriteria inklusi diperoleh 15 artikel penelitian yang akan di telaah. Hasil penelitian menunjukkan bahwa hipertensi merupakan faktor resiko terjadinya peningkatan kadar protein urin. Diharapkan penderita hipertensi secara rutin memeriksakan dan mengontrol tekanan darahnya, bila perlu melakukan pemeriksaan komplikasi hipertensi, untuk mengurangi faktor risiko salah satunya gangguan fungsi ginjal.