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All Journal Martabe : Jurnal Pengabdian Kepada Masyarakat Bharasumba Jurnal Multidispliner Jurnal Multidisipliner Kapalamada JIMR : Journal Of International Multidisciplinary Research
Zuriati Uno, Wiwit
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PEMANFAATAN ECENG GONDOK SEBAGAI ANTIBAKTERI KARIES GIGI UNTUK KESEHATAN GIGI DAN MULUT MASYARAKAT DESA BUA KABUPATEN GORONTALO Sy Pakaya, Mahdalena; Zuriati Uno, Wiwit; Ramadani Putri Papeo, Dizky; Hiola, Paramita; Qarlan Pratama, Mohammad; Zahra Zakia, Wavika; Fazril Pakaya, Mohamad
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 8, No 9 (2025): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v8i9.3804-3811

Abstract

Karies gigi merupakan salah satu masalah kesehatan gigi dan mulut yang paling umum ditemukan di Indonesia, dengan prevalensi mencapai 88,8% di kalangan penduduk dewasa. Program Pengabdian kepada Masyarakat yang dilaksanakan di Desa Bua, Kabupaten Gorontalo, bertujuan untuk meningkatkan pemahaman masyarakat tentang pentingnya menjaga kebersihan gigi dan mulut, sekaligus memberdayakan mereka dengan memanfaatkan eceng gondok (Eichhornia crassipes) sebagai bahan antibakteri dalam upaya pencegahan karies. Program ini menerapkan pendekatan edukatif dan partisipatif, di mana masyarakat diberikan penyuluhan mengenai penyebab karies, pentingnya menyikat gigi secara teratur, dan cara memanfaatkan eceng gondok untuk membuat produk kesehatan seperti obat kumur herbal. Evaluasi yang dilakukan dengan menggunakan pre-test dan post-test mengindikasikan adanya kemajuan yang signifikan dalam pemahaman dan kemampuan peserta. Selain itu, pelatihan yang diberikan juga berhasil mengajarkan masyarakat, khususnya ibu rumah tangga, bagaimana cara mengolah eceng gondok menjadi produk bernilai tambah yang dapat dikembangkan menjadi usaha mikro. Selain memberikan manfaat bagi kesehatan, program ini juga berperan dalam pemberdayaan ekonomi masyarakat lokal dan mendukung pelestarian lingkungan dengan mengoptimalkan pemanfaatan eceng gondok yang tumbuh melimpah di Danau Limboto. Melihat hasil yang diperoleh, program ini memiliki peluang untuk diterapkan di daerah lain dengan kondisi serupa, dengan tujuan untuk meningkatkan kualitas hidup masyarakat secara komprehensif.
UPAYA PENINGKATAN PENGETAHUAN MASYARAKAT TENTANG INFEKSI PNEUMONIA PADA ANAK SERTA PEMANFAATAN POTENSI LOKAL UNTUK INDONESIA BEBAS PNEUMONIA Sy Pakaya, Mahdalena; Zuriati Uno, Wiwit; Ain Thomas, Nur; Ar’syifa Wijaya, Hudan
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 8, No 6 (2025): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v8i6.2543-2549

Abstract

Infeksi pernapasan akut yang menyerang paru-paru dapat disebabkan oleh bakteri, virus, atau jamur. Meskipun penyakit ini dapat menyebabkan kematian pada semua kelompok usia, bayi dan balita adalah yang paling rentan. Anak-anak di bawah dua tahun lebih rentan terhadap pneumonia daripada orang dewasa. Dari 6,6 juta balita yang meninggal dunia, 1,1 juta di antaranya adalah pneumonia, dan 99 persen dari kasus ini terjadi di negara berkembang. Di Indonesia, pneumonia sangat umum di kalangan anak-anak usia 1-4 tahun, dengan kasus tertinggi terjadi pada orang-orang dengan kuintil indeks kepemilikan terbawah (2,74%). Pada tahun 2013, insiden pneumonia tertinggi terjadi pada anak usia 12-23 bulan, meningkat menjadi 6,0% pada tahun 2018. Di Provinsi Sulawesi Selatan, prevalensi pneumonia tercatat sebesar 1,2% pada tahun 2022, dengan angka tertinggi di Kota Pare-Pare (2,57%). Berdasarkan karakteristik balita, populasi tertinggi ditemukan pada usia 24-35 bulan (1,67%), jenis kelamin perempuan (1,21%), dan tinggal di pedesaan (1,56%). Dibandingkan dengan penyakit lain, pneumonia menyebabkan kematian lebih tinggi. Salah satu metode utama untuk menangani infeksi adalah penggunaan antibiotik; namun, sekitar 40-62% penggunaan antibiotik tidak tepat, yang dapat menyebabkan resistensi obat atau Multi Drug Resistance Organisms (MDROs). Penelitian Ettore menunjukkan bahwa efek samping seperti ruam kulit, urtikaria, diare, mual, dan muntah dapat terjadi setelah penggunaan antibiotik pada anak-anak. Penggunaan antibiotik harus dilakukan dengan hati-hati pada anak-anak karena sistem kekebalan tubuh mereka belum matang dan lebih rentan terhadap infeksi. Respon tubuh anak terhadap berbagai obat. Tubuh anak berbeda dengan tubuh orang dewasa dalam hal penyerapan, distribusi, metabolisme, dan eliminasi obat. Ini dapat memengaruhi efektivitas dan efek samping obat. Banyak tanaman lokal saat ini digunakan sebagai obat tradisional untuk berbagai penyakit, seperti infeksi. Daun miana (Coleus scutellarioides) dan jeruk nipis (Citrus aurantifolia) adalah tanaman yang sering digunakan oleh masyarakat dan diyakini dapat mencegah dan mengobati penyakit saluran pernapasan. Untuk menghentikan infeksi pneumonia di Indonesia, sangat penting untuk memberikan pendidikan tentang pneumonia dan manfaat tanaman herbal lokal Gorontalo untuk mencegah infeksi pneumonia pada anak.
POTENSI LIMBAH IKAN LELE (Clarias sp.) SEBAGAI SUMBER KOLAGEN ALAMI UNTUK APLIKASI FARMASI DAN KOSMETIKA: KAJIAN LITERATUR Zuriati Uno, Wiwit; Djamil, Cahniar; Alvionita, Mita; Pratiwi Iman, Dian
Jurnal Multidisipliner Bharasumba Vol 3 No 03 (2024): BHARASUMBA: Jurnal Multidisipliner
Publisher : Pusat Studi Ekonomi, Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62668/bharasumba.v3i03.1835

Abstract

Catfish (Clarias sp.) waste, which includes bones, skin, and scales, represents a potential natural source of collagen with significa nt economic value. Collagen plays an important role in pharmaceuti cal, cosmetic, and functional food industries due to its bioactive proper ties such as antioxidant, antimicrobial, and tissue-regenerative capabil ities. This literature review aims to explore the potential utilization of catfish waste as a collagen source and its possible combination with bioactive plants, such as Moringa oleifera, Hibiscus sabdariffa, or mic roalgae, to enhance biological activity & formulation stability. The rev iew indicates that acid & enzymatic extraction methods are the most eff ective techniques for obtaining high-quality collagen from catfish was te. Recent studies reveal that catfish collagen possesses an ami no acid composition similar to mammalian collagen, with high levels of glycine & proline. Furthermore, combining catfish collagen with bio active pla nt extracts enhances antioxidant & antidiabetic properties. This study highlights that collagen development from catfish was teoffe rs an inno vative, eco-friendly biotechnological approach aligned with circular economy principles & great potential for value prod uct development.
COLLAGEN AND BIOACTIVE PEPTIDES FROM HULU'U FISH SCALES AND GILLS (GIURIS MARGARITICUS) AS POTENTIAL AGENTS FOR DIABETIC WOUND THERAPY Zuriati Uno, Wiwit; Naysila, Siti; Salsahbila Usman, Adelin
Jurnal Multidisipliner Kapalamada Vol. 4 No. 04 (2025): JURNAL MULTIDISIPLINER KAPALAMADA
Publisher : Pusat Studi Ekonomi, Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62668/kapalamada.v4i04.1938

Abstract

This study aimed to explore collagen content and bioactive peptides derived from scales and gills of endemic upstream fish from Gorontalo, to evaluate their antioxidant activity, fibroblast proliferation stimulation in vitro, and antidiabetic potential through inhibition of ?-glucosidase and ?-amylase enzymes, supporting the development of local diabetic wound therapy agents. Fish scales and gills were dried, ground, and extracted using acetic acid. Collagen was precipitated, dried, and hydrolyzed with pepsin to obtain peptides <10 kDa. Collagen content was determined using a hydroxyproline assay. Antioxidant activity was evaluated using DPPH and ABTS assays. Fibroblast proliferation was assessed by a scratch assay under hyperglycemic conditions (25 mM glucose). Antidiabetic potential was examined through in vitro inhibition of ?-glucosidase and ?-amylase. Results showed that collagen content in scales was higher than in gills. Both extracts exhibited significant antioxidant activity, enhanced fibroblast proliferation, and demonstrated inhibitory effects on ?-glucosidase and ?-amylase. These findings indicate that fish scales and gills are promising sustainable biomaterials for diabetic wound therapy and local pharmaceutical innovation.
ANTIOXIDANT ACTIVITY EVALUATION OF CATFISH (CLARIAS SP.) COLLAGEN EXTRACT USING DPPH AND ABTS METHODS Hiola, Faramita; Zuriati Uno, Wiwit; Sy. Pakaya, Mahdalena; Hutuba, Ariani
Jurnal Multidisipliner Kapalamada Vol. 4 No. 04 (2025): JURNAL MULTIDISIPLINER KAPALAMADA
Publisher : Pusat Studi Ekonomi, Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62668/kapalamada.v4i04.1964

Abstract

This study aimed to evaluate the antioxidant activity of collagen extracted from catfish (Clarias sp.) using DPPH and ABTS assays. The research procedures included sample preparation, collagen extraction using an acid-based method, and antioxidant analysis at concentrations ranging from 20–100 ppm. The degree of hydrolysis (DH) was measured to determine the effectiveness of Alkalase in producing bioactive peptides. The results showed that higher enzyme concentrations led to increased DH, with the highest value of 62.42% obtained at 3% Alkalase. Antioxidant activity increased with sample concentration, with maximum inhibition values of 78.57% (DPPH) and 85.00% (ABTS) at 100 ppm. The ABTS assay exhibited higher sensitivity than DPPH. These findings indicate that catfish collagen has strong potential as a safe and natural antioxidant source suitable for further development in food, pharmaceutical, and cosmetic applications.
ADVANCES IN PROTEIN SYNTHESIS TECHNOLOGY AND THEIR IMPLICATIONS FOR FUTURE PROTEIN AVAILABILITY: A NARRATIVE REVIEW Zuriati Uno, Wiwit; Tompe, Siti Sulistiani; Miftahuljannah, Salwa; Pulukadang, Azqia Maharani; Rahmadani J. Hako, Farelia Rizkita; Dunggio, Karim Putra
JIMR : Journal Of International Multidisciplinary Research Vol 4 No 02 (2025): JIMR : Journal Of International Multidisciplinary Research
Publisher : Pusat Studi Ekonomi Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62668/jimr.v4i02.1971

Abstract

The availability of conventional protein sources is increasingly limited due to population growth, climate change, and limited land, so innovation is needed in providing more efficient and sustainable protein. This study aims to examine the development of protein synthesis technology and its implications for the availability of future protein sources. The method used is a literature review by examining scientific publications published from 2015-2024 searched through Google Scholar. The results of the study indicate that recombinant technology is able to produce high-quality functional proteins through genetic engineering of microorganisms, while microbial fermentation based on agro-industrial waste offers cheap and environmentally friendly Single Cell Protein production. In addition, increased production of poultry, eggs, and milk is the main support for the national animal protein supply. Overall, the development of protein synthesis technology provides a strategic opportunity to meet global protein needs through a resource-efficient, scalable, and sustainability-oriented approach.
ANTIOXIDANT ACTIVITY OF NIRA SEED WASTE (ARENGA PINNATA) EXTRACTS USING DPPH METHOD Zuriati Uno, Wiwit; Anggraini, Rifka; Solihin, Anggi Pratama; Akuba, Juliyanti
JIMR : Journal Of International Multidisciplinary Research Vol 4 No 02 (2025): JIMR : Journal Of International Multidisciplinary Research
Publisher : Pusat Studi Ekonomi Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62668/jimr.v4i02.1991

Abstract

Agricultural waste from Nira (Arenga pinnata) seeds has attracted increasing attention due to its potential bioactive compounds and value-added applications. Objective: This study aims to evaluate the antioxidant activity of nira seed waste (Arenga pinnata) using solvents with different polarity levels. Method: The research employed an experimental laboratory method with maceration extraction using ethanol, acetone, and n-hexane. Antioxidant activity was analyzed using the DPPH radical scavenging assay measured by UV–Vis spectrophotometry. Results: The results showed that solvent polarity influenced extraction yield, phytochemical composition, and antioxidant potential. The ethanol extract exhibited the strongest antioxidant activity due to its effectiveness in extracting phenolic and flavonoid compounds. These findings indicate that nira seed waste has promising potential as a natural antioxidant source and pharmaceutical raw material supporting the zero waste concept.
STANDARDIZATION OF SPECIFIC AND NON-SPECIFIC PARAMETERS, PHYTOCHEMICAL ANALYSIS, AND KLT PROFILE OF JACKFRUIT SEED EXTRACT (ARTOCARPUS HETEROPHYLLUS LAM) Zuriati Uno, Wiwit; Hulopi, Aprilia; Rahma Bau, Fadhilah Nur; Suronoto, Hariyanto; Amalia Lantapa, Nazwa; Usman, Sasya Ramadhani
JIMR : Journal Of International Multidisciplinary Research Vol 4 No 02 (2025): JIMR : Journal Of International Multidisciplinary Research
Publisher : Pusat Studi Ekonomi Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62668/jimr.v4i02.2004

Abstract

This study aimed to determine the specific parameters, non-specific parameters, phytochemical screening results, and TLC profile of jackfruit seed extract. The evaluations included organoleptic assessment, moisture content, total ash content, microbial contaminat ion, phytochemical identification, and TLC analysis using n-hexane: ethyl acetate eluents. The results showed that the extract was viscous, yellow-brown, and had a characteristic aroma; the moisture content was 6% and the total ash content was 2.85%, both meeting the quality requirements. Microbial contamination indicated acceptable values with total plate count at dilutions 10?²–10?³ and yeast-mold count at dilutions 10?¹–10?², remaining below the maximum limits. Phytochemic al screening identified the presence of alkaloids and steroids/terpen oids, while flavonoids, tannins, and saponins were not detected. TLC profiling produced several Rf values indicating the dominance of non-polar to semi-polar compounds. These findings demonstrate that jack fruit seed extract meets physical, chemical, and microbiological qua lity standards and presents a consistent chemical profile, supporting its potential for use as a raw material in herbal product development.
ANALYSIS OF SPECIFIC AND NON SPECIFIC PARAMETERS OF GOROHO BANANAS (Musa acuminata L.) Zuriati Uno, Wiwit; Arginggang, Rionaldo; Sulasdi, Lya Yulyani; A. Masulili, Makhfudia; Nasib, Sri Safitri; Wijaya, Hudan
JIMR : Journal Of International Multidisciplinary Research Vol 4 No 02 (2025): JIMR : Journal Of International Multidisciplinary Research
Publisher : Pusat Studi Ekonomi Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62668/jimr.v4i02.2007

Abstract

Goroho banana (Musa acuminata subsp. goroho) is a local Indonesian plant with potential as a traditional medicine due to its secondary metabolite content. This study aimed to standardize goroho banana extract through testing specific and nonspecific parameters to ensure the quality, safety, and quality of the extract. The method used was maceration extraction with 96% ethanol. Specific parameters tested included organoleptic testing, water-soluble extract content, ethanol- soluble extract content, and phytochemical screening. Nonspecific parameters included water content and microbial contamination testing. The results showed that goroho banana extract was thick, light yellow, and had a distinctive banana odor. The water-soluble extract and ethanol content were each 16.6%, meeting quality requirements. Phytochemical screening revealed the presence of flavonoids and saponins, while alkaloids yielded negative results in the Mayer test. Nonspecific testing indicated that the water content and microbial contamination were within safe limits according to standards. Based on these results, goroho banana extract meets the quality criteria for herbal extracts and has the potential to be developed as a raw material for traditional medicine
STANDARDIZATION OF SPECIFIC AND NON-SPECIFIC PARAMETERS OF DAYAK ONION BULB (ELEUTHERINE PALMIFOLIA L. MERR.) Zuriati Uno, Wiwit; Salfadila Hasan, Nazwa; N. Tilola, Serlin; Rumampuk, Salwa; Qarlan Pratama, Mohammad; Kumala Arista, Meira
JIMR : Journal Of International Multidisciplinary Research Vol 4 No 02 (2025): JIMR : Journal Of International Multidisciplinary Research
Publisher : Pusat Studi Ekonomi Publikasi Ilmiah dan Pengembangan SDM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62668/jimr.v4i02.2008

Abstract

This study aimed to determine the specific and non-specific parameters of Dayak onion bulb extract as a basis for herbal standardization. The research methods included organoleptic identification, phytochemical screening, Thin Layer Chromatography (TLC) analysis, and determination of non-specific parameters, namely moisture content, total ash content, Total Plate Count (TPC), and Yeast and Mold Count (YMC). Phytochemical screening showed the presence of alkaloids, flavonoids, tannins, and saponins, while steroids and terpenoids were not detected. The TLC profile showed several spots with varying Rf values, indicating the presence of compounds with different polarity levels. The moisture content (5.07%) and total ash content (4.31%) met the standards of the Indonesian Herbal Pharmacopoeia. TPC (5.4 × 10² CFU/mL) and YMC (3.2 × 10² CFU/mL) were below the permissible limits. These results indicate that Dayak onion bulb extract meets the required specific and non-specific parameters and is suitable for use as a standardized herbal raw material.
Co-Authors A. Masulili, Makhfudia Akuba, Juliyanti Alvionita, Mita Amalia Lantapa, Nazwa Anggraini, Rifka Ar’syifa Wijaya, Hudan Arginggang, Rionaldo B. Anwar, Alvionita Djamil, Cahniar Dunggio, Karim Putra Fazril Pakaya, Mohamad Hiola, Faramita Hiola, Paramita Hulopi, Aprilia Hutuba, Ariani Kuengo, Aditya Kumala Arista, Meira Mahdalena Sy Pakaya Miftahuljannah, Salwa N. Tilola, Serlin Nasib, Sri Safitri Naysila, Siti Nur Ain Thomas Papeo, Dizky Ramadani Putri Pratiwi Iman, Dian Pulukadang, Azqia Maharani Putri Delia, Faizha Qarlan Pratama, Mohammad Rahma Bau, Fadhilah Nur Rahmadani J. Hako, Farelia Rizkita Rumampuk, Salwa Salfadila Hasan, Nazwa Salsahbila Usman, Adelin Solihin, Anggi Pratama Sulasdi, Lya Yulyani Suronoto, Hariyanto Tompe, Siti Sulistiani Usman, Sasya Ramadhani Wijaya, Hudan Zahra Zakia, Wavika