Claim Missing Document
Check
Articles

Found 7 Documents
Search

Time-dependent Expression of Caspase-3 and Degeneration of Lateral Rectus Muscle on Experimental Esotropia in Rabbits Luki Indriaswati; Nurwasis; Gatut Suhendro; Soetjipto; Retno Handajani
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14785

Abstract

Background: To identify correlation between caspase-3 expression and degeneration of lateral rectus muscleon experimental esotropia in rabbits by using time dependent analysis. Methods: Twenty four rabbits weredivided into 4 groups, first month sham (S1); second month sham (S2); first month esotropia (E1); andsecond month esotropia (E2) model groups. Immunohistochemical and haematoxyllin eosin staining wereperformed. Results: In first month observation no significant difference in caspase-3 expression between S1(1.56 ± 1.03) and E1 (3.93 ± 1.66) groups (p >0.05) and in the degeneration score of lateral rectus musclebetween S1 (1.33 ± 1.36) and E1 (3.83 ± 2.04) groups (p> 0.05). In second month observation no significantdifference in caspase-3 expression between S2 (1.80 ±1.08) and E2 (6.50 ± 3.26) groups (p >0.05); butthere was significant difference in the degeneration score of lateral rectus muscle between S2 (1.16 ± 1.16)and E2 (4.50 ± 1.04) groups (p <0.05). There was a significant correlation between caspase-3 expressionand the degeneration score of lateral rectus muscle (p=0.020; r=0.471). Conclusion: On the experimentalesotropia with prolonged lateral muscle contraction in rabbits, the increasing trend of caspase-3 expressionhas a correlation with the increasing degeneration score of lateral rectus muscle.
Effect of Cacao on Plasma F2-Isoprostane Level, CD34 and ICAM-1 Expression of Coronary Arteries in Cigarette Smoking Exposed Rats Dina Helianti; Soetjipto; Widjiati; I Ketut Sudiana
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15729

Abstract

This research aimed to evaluate cardioprotective effects of cacao in smoking exposure condition that the effects were mediated through the anti-oxidant pathway by measure plasma F2-isoprostane level, Endothelial Progenitor Cell (EPC) enhancement by expression of CD34, while dysfunction endothelial condition was measured by expression of ICAM-1 in coronary arteries. This study subjected rats, divided into four groups: the normal control group (2 ml of aqua bidest, air exposure); the cigarette control group (2 ml of aqua bidest, cigarette smoke); cacao group 1 (1205 mg/kg BW/day, cigarette smoke); cocoa group 2 (2410 mg/kg BW/day, cigarette smoke). The oxidant biomarker, F2-isoprostane level was assessed using ELISA; CD34, and ICAM-1 expression in coronary arteries by immunohistochemistry. Cacao 1205 mg/kg BW/day significantly decreases plasma F2-isoprostane level, and ICAM-1 expression of coronary arteries in cigarette smoking exposed rat (p < 0.05) but there was not a significant increases CD34 (p < 0.05). Cocoa in cigarette smoke-exposed rats can prevent endothelial dysfunction through decrease F2-isoprostane but not increase CD34. The results of this study can be used as a basis for preventing endothelial dysfunction due to cigarette smoke by using cacao.
Associations between P53, Transforming Growth Factor Beta-1, and Interleukin-10 Serum Levels with Advanced Liver Disease and Hepatitis B Virus Infection Citrawatidyahkencono Wungu; Mochamad Amin; Ulfa Kholili; Gwennyichsan Prabowo; Poernomoboedi Setiawan; Soetjipto; Retno Handajan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15736

Abstract

Music Therapy for Chronically ill Patient Putriana, Maria Magdalena Greda; Soetjipto; Hendy Muagiri Margono; Budi Kristiano
Jurnal Psikiatri Surabaya Vol. 11 No. 1 (2022): May
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v11i1.23379

Abstract

Chornic illness puts a person at increased risk for developing anxiety or an anxiety disorder. Most often, chronic diseases are incurable, and treatment is focused primarily on the management of symptoms. Patients with chronic diseases commonly report fears of illness or symptoms recurring or worsening. The more this illness may consume a person's life and thoughts, the more negativity tends to take over. Music can affect a person at psychological or emotional aspect during treatment of an illness or injury.
Improved Communication Skills Assisting Cancer Patients Through Counseling Training Palliative Volunteers in Surabaya Putra, Patria Yudha; Febria Rike Erliana; Novelita Mesah; Feytie Magda Mawey; Lia Jessica; Christopher Aditya Purba; Pemilda Dian Catur Ayu Wisnu Putri; Eden; Deviyana Soetjipto; Konginan, Agustina; Erikavitri Yulianti; Soetjipto; Marlina S. Mahajuddin
Jurnal Psikiatri Surabaya Vol. 11 No. 2 (2022): November
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v11i2.34378

Abstract

Introduction: The prevalence of tumors/cancer in Indonesia is increasing. Many cases of cancer at an advanced stage experience severe symptoms and cause suffering that has not been handled properly. Palliative care helps a cancer survivor and his or her family to live a more comfortable life to have a better quality of life. Methods: For this reason, a team that works in an integrated manner includes both medical and non-medical personnel, including volunteers. The role of volunteers in palliative care teams varies according to need and can be involved in hospital care, or at home, expected to bridge between health care institutions and patients. Psychiatrists at Dr. Soetomo General Hospital Surabaya and their residents try to give four sessions of volunteer training to raise awareness, provide health education, or even provide some simple type of medical care and work as counselors. Results: After giving four training sessions every week, the ability of palliative teams had increased. They have the capability to communicate more effectively and efficiently, which is therapeutic, so it is necessary to provide them with counseling skills to listen to, understand, and respond positively when communicating with cancer patients and their families.
The Profile of Factors Influencing Condom Usage Among Transgender Population: A Systematic Review Bin Patawari, Anwar Mohamad; Samsriyaningsih Handayani; Soetjipto; Abdul Khairul Rizki Purba
Journal of Scientific Research, Education, and Technology (JSRET) Vol. 3 No. 3 (2024): Vol. 3 No. 3 2024
Publisher : Kirana Publisher (KNPub)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58526/jsret.v3i3.448

Abstract

Human Immunodeficiency Virus is still a problem around the world and in Indonesia, one of the most exposed is the Transgender community and one way to prevent HIV transmission is through condoms. This systematic review aims to find out the factors that influence condom use in transgender women. Literature searches were conducted using PubMed with the keywords 'transgender', 'peer support', 'knowledge', 'condom use'. From 202 studies that were screened using Preferred Reporting Items for Systematic review and Meta-Analyses (PRISMA), 2 studies were obtained and analyzed.: Data that was obtained such as research method, participants, exposure, and outcome such as condom use and their factors were obtained. Based on analyses on condom use factors, the knowledge of condom use is not as effective in improving condom use, another factor is that increase in trust causes the participants partners to not use condom as often, last factor is Peer support towards the partners has an increase in condom usage. Further research with other factors not found is needed to give better comparison
Effectiveness of Community Smoking Prevention Education in Enhancing Adolescent’s Knowledge in Banyuwangi Indonesia Azimatul Karimah; Soetjipto; Izzatul Fithriyah; Sheila Maryam Gautama; Agustina Sjenny; Adila Taufik Syamlan; Adhilah, Nindy; Dina Faizatur Rahmah; Williana Suwirman; Virzi Aliyyah Rahma; Teisha Jediya Videlia Marantika; Rifat Nurwita Kusumaningtyas; Andyani Pratiwi; Rizka Solehah
Jurnal Psikiatri Surabaya Vol. 14 No. 1 (2025): May
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v14i1.64486

Abstract

Introduction: Tobacco consumption increases the risk of chronic diseases and death. In Indonesia, the prevalence of active smokers is estimated to reach 27% of the population, or 70 million people, with 7.4% of them aged 10-18 years. The aim of this study is to assess the effectiveness of community smoking prevention education in enhancing adolescent knowledge in Banyuwangi, Indonesia. Methods: This study used a quasi-experimental research design with a pre- and post-test one-group approach. In this study, we employed total sampling as our sampling technique. The samples were students of class X SMA Negeri 1 Giri Banyuwangi, aged 14-16 years old. The intervention includes a presentation on long-term health consequences, the risk of addiction, and the adverse effects of smoking. Psychiatrists led our intervention, sharing general knowledge about smoking behavior and its risk for health outcomes. Results: The study ultimately employed a final sample of 49 participants. The paired t-test increased from the pre-test (53.47) to the post-test (63.47) score average. The standard deviation for the pre-test and post-test is 14.513. Eventually, the standard error mean for the pre-test and post-test is 2.073. The average learning outcome in the pre-test (53.47) is less than that of the post-test (63.47), and the p-value is 0.000, which is less than 0.05. Conclusion: The study’s results indicated that prevention education had a significant impact on increasing adolescents’ knowledge about smoking (p = 0.000). Regular prevention programs could further enhance adolescents’ understanding of the topic.