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All Journal Jurnal Sain Veteriner Biotika: Jurnal Ilmiah Biologi Majalah Kedokteran Bandung Althea Medical Journal ODONTO Dental Journal Nusantara Medical Science Journal Jurnal Sistem Kesehatan Oto Rhino Laryngologica Indonesiana Narra J Jurnal Sains dan Teknologi Farmasi Indonesia Media Dermato-Venereologica Indonesiana Odonto dental journal Jurnal Penyakit Dalam Indonesia
Chrysanti -
Faculty Of Medicine Universitas Padjadjaran
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Veterinary

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Gambaran Klinis Pasien Terduga Tuberkulosis Paru Resisten Obat (TB-RO) dengan Kolonisasi Candida sp. di Rumah Sakit Hasan Sadikin Bandung Zalfa, Hasna Rafifah Zahira; Kulsum, Iceu Dimas; Suryadinata, Hendarsyah; Chrysanti, Chrysanti; Dewi, Intan Mauli Warma
Jurnal Penyakit Dalam Indonesia Vol. 11, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. Candida sp. is a fungus that lives as a commensal in human body, but may cause infection upon immune suppression. The decrease in immunity due to TB infection and long-term use of antibiotics in TB patients may increase the risk of the Candida sp. colonization in patient. Data regarding the prevalence of Candida sp. colonization in TB patients and its impact has not been widely reported. This study was conducted to determine the prevalence and clinical characteristics of presumptive drug-resistance TB patients with Candida sp. colonization. Methods. A cross-sectional study was conducted using secondary data from a previous study in 2018 at the DR-TB clinic in Hasan Sadikin General Hospital Bandung, Indonesia. Patients who were included in the study were aged 18 years or above, presented with pulmonary TB symptoms, and had minimum 5 months of TB treatment history. Candida sp. growth on sputum was examined by culture on CHROMagar® media. Results. One hundred and twenty-two patients met the inclusion and exclusion criteria. The prevalence of Candida sp. colonization in presumptive drug-resistance TB patients was 54.9%. The species found were mostly Candida albicans (71.6%), Candida glabrata and Candida parapsilosis (14.9%), and Candida tropicalis (5.9%). The predominant symptoms of pulmonary tuberculosis included a persistent cough lasting two weeks or longer and productive cough (100%), while the most frequently observed abnormalities on radiological scans were nodules and patchy lesions (98.5%). There were no significant differences between patients with positive and negative Candida sp. colonization. Conclusions. More than 50% of presumptive drug-resistant TB patients at the MDR-TB clinic in Hasan Sadikin General Hospital had positive results of Candida sp. culture on their sputum. The most common clinical manifestations were coughing for 2 weeks or more, productive cough, hemoptysis, fever, chest pain, shortness of breath, night sweats, weight loss, and reduced appetite. Future studies should be conducted to determine the long-term outcome of fungal colonization in these patients.
ANGKA KEJADIAN DAN KARAKTERISTIK TINEA KAPITIS DI RSUP Dr. HASAN SADIKIN BANDUNG PERIODE 2016−2020 Risa Miliawati Nurul Hidayah; Khairani Dewi Triana Anwar; Hendra Gunawan; Reiva Farah Dwiyana; Chrysanti Murad; Lies Marlysa Ramali
Media Dermato-Venereologica Indonesiana Vol 49 No 3 (2022): Media Dermato-Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v49i3.299

Abstract

Tinea kapitis adalah infeksi jamur pada rambut dan kulit kepala yang disebabkan oleh jamur dermatofita. Penyakit ini sering terjadi pada anak-anak hingga masa prepubertas. Data mengenai tinea kapitis belum tersedia secara menyeluruh di Indonesia. Penelitian ini bertujuan untuk memberikan gambaran tentang angka kejadian dan karakteristik tinea kapitis, khususnya di daerah Jawa Barat. Penelitian ini merupakan suatu penelitian retrospektif potong lintang yang disajikan secara deskriptif. Data dikumpulkan dari rekam medis pasien di Klinik Dermatologi Infeksi Poliklinik Dermatologi dan Venereologi Rumah Sakit Umum Pusat (RSUP) Dr. Hasan Sadikin Bandung.Dari hasil penelitian ini didapatkan 67 pasien tinea kapitis dari 617 pasien dermatomikosis di RSUP Dr. Hasan Sadikin tahun 2016−2020. Jenis tinea kapitis yang ditemukan ialah tipe gray patch (56,7%), kerion (20,9%), black dot (4,5%), favus (3%) dan pasien yang tidak diketahui jenis tinea kapitisnya (14,9%). Kejadian pada laki-laki hamper sama dengan perempuan dan paling banyak terjadi pada kelompok usia 5−9 (35,8%) tahun. Pemeriksaan lampu Wood dilakukan pada 44 pasien, didapatkan hasil flouresensi kuning kehijauan sebesar 50,7%. Pemeriksaan dermoskopi menunjukkan hasil paling banyak berupa comma hairs dan broken hair. Pemeriksaan langsung dengan larutan KOH 10−20% menunjukkan hasil positif sebesar 79,1%. Data kultur yang didapatkan dari 18 pasien., M. canis sebagai penyebab terbanyak (94 %). Kesimpulan pada penelitian ini, jenis tinea kapitis yang paling sering ditemukan adalah tipe gray patch, lebih banyak ditemukan pada laki-laki, kelompok usia 5–9 tahun, dan riwayat kontak dengan hewan. Pendekatan secara laboratorium dilakukan sehingga mendukung dalam penegakan diagnosis tinea kapitis.
Oral Health Care and Aspiration Pneumonia Salma, Yasmin Hanifa; Murad, Chrysanti; Megantara, Imam
Odonto : Dental Journal Vol 11, No 2 (2024): December 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.2.347-358

Abstract

Background: Oral health care is important to prevent aspiration pneumonia. Poor oral hygiene in elderly patients heightens the risk of aspiration pneumonia due to the growth of potential periodontopathogen bacteria. This literature review aims to describe the effect of oral health care on the incidence of pneumonia and/or the number of oral bacteria.Method: The literature search was conducted based on the PRISMA guideline with the PICO framework by utilizing electronic search engines in databases: PubMed, Cochrane's Library, and Google Scholar from March through May 2024. All articles to be reviewed were ‘’full text” published from 2014 to 2024. An eligibility assessment was conducted based on inclusion and exclusion criteria; thus, seven articles were selected.Result: Mechanical tooth and mouth cleaning, in addition to using mouthwash and moisturizing agents, effectively reduces the risk of aspiration pneumonia in the elderly.Conclusion: Oral health care with mechanical and pharmacological interventions are deemed appropriate to be given to elderly individuals to prevent aspiration pneumonia.
Epidemiology and population-based incidence of influenza in two communities, Bandung district, West Java, Indonesia, 2008–2011 Agustian, Dwi; Mutyara, Kuswandewi; Murad, Chrysanti; M. Uyeki, Timothy; B. Kartasasmita, Cissy; Simoes, Eric AF.
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.981

Abstract

Influenza surveillance is important for monitoring influenza virus circulation and disease burden to inform influenza prevention and control measures.  The aim of this study was to describe the epidemiology and to estimate the incidence of influenza in two communities in West Java, Indonesia, before and after the 2009 H1N1 pandemic. A population-based surveillance study in the community health care setting was conducted to estimate the annual incidence of influenza. A real-time reverse transcription polymerase chain reaction (RT-PCR) assay was used for influenza case ascertainment. A population census was implemented to calculate the population at risk and estimate community health care utilization rate. The mean annual incidence of influenza A and B, adjusted for healthcare utilization, was 1.6 (95%CI: 1.3–2.0) and 0.7 (95%CI: 0.5–1.0) per 1000 persons, respectively, with the most affected group being young and school-age children. The annual cumulative incidence of influenza A for children under five in 2009, 2010, and 2011 was 7.0 (95%CI: 4.4–11.2), 10.6 (95%CI: 7.3–15.4), and 6.3 (95%CI: 3.8–10.2). For influenza B was 4.3 (95%CI: 2.4–7.8), 2.0 (95%CI: 0.8–4.7), and 0.4 (95%CI: 0.1–2.8), respectively. This study highlights that the incidence of influenza among young and school-age children is consistently higher compared to adults and the elderly throughout these periods. These populations are potential targets for influenza vaccination in Indonesia.
Oral Health Care and Aspiration Pneumonia Salma, Yasmin Hanifa; Murad, Chrysanti; Megantara, Imam
Odonto : Dental Journal Vol 11, No 2 (2024): December 2024
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.11.2.347-358

Abstract

Background: Oral health care is important to prevent aspiration pneumonia. Poor oral hygiene in elderly patients heightens the risk of aspiration pneumonia due to the growth of potential periodontopathogen bacteria. This literature review aims to describe the effect of oral health care on the incidence of pneumonia and/or the number of oral bacteria.Method: The literature search was conducted based on the PRISMA guideline with the PICO framework by utilizing electronic search engines in databases: PubMed, Cochrane's Library, and Google Scholar from March through May 2024. All articles to be reviewed were ‘’full text” published from 2014 to 2024. An eligibility assessment was conducted based on inclusion and exclusion criteria; thus, seven articles were selected.Result: Mechanical tooth and mouth cleaning, in addition to using mouthwash and moisturizing agents, effectively reduces the risk of aspiration pneumonia in the elderly.Conclusion: Oral health care with mechanical and pharmacological interventions are deemed appropriate to be given to elderly individuals to prevent aspiration pneumonia.
ANGKA KEJADIAN DAN KARAKTERISTIK LESI PATOLOGI CALICIVIRUS PADA KUCING (Felis catus) DI VEE VET BANDUNG PERIODE AGUSTUS-SEPTEMBER 2024 Arifah, Kaila Nurul; Khairani, Shafia; Murad, Chrysanti; Felani, Yulita Nurul Hikmah
Jurnal Sain Veteriner Vol 43, No 2 (2025): Agustus
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.101759

Abstract

Feline calicivirus merupakan penyakit akibat virus yang sangat menular pada kucing. Penyakit ini menyerang saluran pernapasan bagian atas. Feline calicivirus memiliki angka morbiditas yang tinggi dengan gejala yang umumnya serupa dengan penyakit lain. Penelitian ini bertujuan untuk mengetahui angka kejadian serta karakteristik lesi patologi feline calicivirus pada kucing di Vee Vet Bandung periode Agustus – September 2024. Metode penelitian ini dilakukan dengan mengambil data langsung kepada seluruh kucing yang datang ke Vee Vet Bandung periode Agustus-September 2024 dengan keluhan lesi pada mulut dan gangguan pernapasan bagian atas. Pengambilan data dilakukan dengan melakukan uji rapid test dan mendokumentasikan lesi untuk mengetahui bentuk serta lokasi lesi pada kucing dengan kriteria yaitu, hasil positif rapid test feline calicivirus, terdapat lesi pada mulut, dan terdapat gangguan pernapasan bagian atas. Selanjutnya, data akan diolah pada microsoft excel yang kemudian akan dibahas secara deskriptif. Hasil penelitian menunjukan bahwa angka kejadian dari feline calicivirus di Vee Vet Bandung periode Agustus-September 2024 tergolong sangat rendah yaitu 0.05%. Hasil tersebut didapatkan dari 4 pasien terdiagnosa feline calicivirus dengan seluruh populasi kucing yang datang sebanyak 722 pasien. Karaktersitik lesi patologi yang muncul pada seluruh kucing terdiagnosis feline calicivirus adalah seluruh kucing memiliki lesi pada mulut berupa ulser kemerahan khususnya pada bagian lidah dan mukosa mulut serta tidak terjadi nekrosis ataupun edema baik itu di wajah atau pawpad.   
The Correlation between Plasma IL-17 Levels, Lymphocyte Counts, and Neutrophil Counts with the Colonisation of Candida sp. in Tuberculosis Patients with a Treatment History Yunivita, Vycke; Anastasia, Mutiara; Warma Dewi, Intan Mauli; Murad, Chrysanti
Nusantara Medical Science Journal Vol. 10 No. 2 (2025): Volume 10 Issue 2, July - December 2025
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v10i2.46139

Abstract

Introduction:  Tuberculosis (TB) patients with a history of ATT therapy are associated with changes in IL-17 levels, lymphocyte counts, and neutrophil counts. Increased IL-17 levels, lymphocyte counts and neutrophil counts indicate colonisation of Candida sp. fungus. Changes in the immune response in TB patients with Candida sp. colonisation may cause complications of TB that affect the treatment success rate. Methods:  This research was designed for observational analytical study with a cross-sectional design. 59 subjects are divided into 3 groups, consisting of 21 TB-positive people with Candida sp. colonisation, 21 TB-positive people without Candida sp. colonisation, and 17 TB-negative people with Candida sp. colonisation. Plasma IL-17 levels are examined using the ELISA test, while the lymphocyte and neutrophil counts are seen from previous study examinations (AFFECT). Results:   The plasma IL-17 levels in the TB-positive group with Candida sp. colonisation were 24.05 pg/ml (IQR 21.77-30.50). The plasma IL-17 levels in the TB-positive group without Candida sp colonisation were 23.08 pg/ml (IQR 19.11-32.46). The plasma IL-17 levels in the TB-negative group with Candida sp. colonisation is 20.72 pg/ml (IQR 18.51-22.84) pg/ml, (p=0.046). However, there are no statistically significant difference was observed in lymphocyte and neutrophil counts (p=0.078). Conclusions:  The differences in IL-17 levels that occur in the TB group with Candida sp colonisation may serve as an immunological signal suggesting the need for fungal assessment if the TB patients do not improve their treatment outcome after undergoing ATT for over 6 months.
Co-Authors Anastasia, Mutiara Arifah, Kaila Nurul B. Kartasasmita, Cissy Cheryl May Chong Sue Faye Chong Jie Hao Chong Jie Hao, Chong Jie Dione Margareth Setiawan Dwi Agustian Faye, Cheryl May Chong Sue Felani, Yulita Nurul Hikmah Gita Widya Pradini Hendarsyah Suryadinata Hendra Gunawan Iceu Dimas Kulsum Ida Parwati Imam Megantara Irvan Afriandi Jefferson Basta Erguna Ginting Jetty - Nurhajati Jetty Nurhajati Jetty Nurhajati Khairani Dewi Triana Anwar Khairani, Shafia kuswandewi Mutiara kuswandewi Mutiara kuswandewi Mutiara, kuswandewi Kuswandewi Mutyara Lestari, Agustina Lies Marlysa Ramali M. Uyeki, Timothy Mauli Warma Dewi, Intan Melati Sudiro Muhammad Fadhil Ihsan Yazid Mutiara Azhara Nurwanti Nareswara, Argya Nurwanti, Mutiara Azhara Pati Aji Achdiat Prima Nanda Fauziah Prima Nanda Fauziah Reiva Farah Dwiyana Risa Miliawati Nurul Hidayah Sadeli Masria Salma, Yasmin Hanifa Sharon Gondodiputro Sharon Gondodiputro shofia safira rahma shofia safira rahma, shofia safira Simoes, Eric AF. Sofiati Dian Sri Sudarwati SRI SUDARWATI Trias Nugrahadi Trias Nugrahadi, Trias widyani rachim widyani rachim, widyani Wulan Ardhana Iswari, Wulan Ardhana Yunivita, Vycke Zalfa, Hasna Rafifah Zahira