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UJI AKTIVITAS GEL LENDIR BEKICOT (ACHATINA FULICA) SEBAGAI PENYEMBUHAN LUKA SAYAT Shoviantari, Fenita; Fajriyah, Shofiatul; Agustin, Ela; Khairani, Shafia
Jurnal Ilmiah As-Syifaa Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.648

Abstract

Snail mucus (Achatina fulica) has a high protein content, which includes beta agglutinin, achasin protein, acharan sulfate, and glycoconjugate. The objectives of this study was to determine differences in physical evaluation of the quality of the gel preparation against snail mucus concentration and to determine the efficacy of snail mucus gel as a wound healing. This study used an experimental research method with a sample of 4 male rats (Rattus novergicus) which were divided into 6 groups in each. The results showed that there was no effect of the physical quality of snail slime gel (Achatina fulica) on the concentration of snail slime formulated. It has been proven in the Kruskall wallis statistical test with the Sig. > 0.05. The results of the wound healing activity test showed an average value of K (+) 49.61%, K (-) 17.48%, P1 48.23%, P2 43.63%, P3 43.43%, and P4 23, 97. Values that indicate differences in K (-) and P4 are evidenced in the Post Hoc LSD test with Sig. <0.05. It can be concluded that the concentration of snail mucus does not affect the physical quality of snail mucus gel preparations and snail mucus gel with snail mucus concentration of 10% is effective in the process of wound healing.
Incidence and Characteristics of Dermatophytosis Lesions in Cats (Felis catus) at Go Pet Care Animal Clinic (2020-2022) Fauziyyah, Salma Aqilla; Dewi, Intan Mauli Warma; Khairani, Shafia
Journal of Parasite Science Vol. 8 No. 2 (2024): Journal of Parasite Science
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jops.v8i2.61621

Abstract

Dermatophytosis, a dermatological condition caused by dermatophyte fungi, affects the superficial keratinized structures of the skin. The primary etiological agents include the genera Microsporum, Trichophyton, and Epidermophyton. This study examines the incidence and characteristics of dermatophytosis lesions in domestic cats (Felis catus) at Go Pet Care Animal Clinic from 2020 to 2022. The research utilized secondary data from the clinic's medical records, which is a significant reference institution in Kabupaten Bandung Barat, to assess the prevalence and features of dermatophytosis within this population. The findings revealed a prevalence of 7.5% in 2020, 11.3% in 2021, and 3.7% in 2022. The incidence was highest in cats under 1 year of age, with a notable frequency in Persian breed cats and males. Common lesions identified included localized alopecia primarily in the ear region, alopecia in the back region, and crust formation also in the back area. This study provides critical insights into the epidemiology and clinical presentation of dermatophytosis in domestic cats, offering guidance for improved diagnosis and management of the condition.
Case Study: Colibacillosis and Coccidiosis in Broiler Chicken Farm Hartady, Tyagita Tyagita; Subagio, Reza Taufik; Khairani, Shafia
Jurnal Sain Veteriner Vol 42, No 3 (2024): Desember
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.89079

Abstract

Colibacillosis and coccidiosis are diseases that often infect broiler chicken. Escherichia coli is an opportunistic commensal bacterium. Colibacillosis often occurs as a secondary infection from other infectious diseases, such as coccidiosis. Coccidiosis is a digestive disease caused by Eimeria sp. Colibacillosis and coccidiosis cause stunting in chicken. This study was conducted to determine pathological features in colibacillosis and coccidiosis cases in broiler, as well as predisposing factors that can increase the risk of these diseases. The results of this study showed that colibacillosis causes pathological changes including peritonitis which is characterized by the formation of fibrinous exudate in the peritoneum, and inflammation of the air sacs. Coccidiosis causes hemorrhagic lesions in the small intestine and cecum. Water pipes that are corroded and overgrown with biofilms can become predispose factor to colibacilosis, because the biofilm layer facilitate the growth of E. coli and cause ineffective disinfection of drinking water. On the other hand, moist litter can promote Eimeria sp. oocysts sporulation; thereby increasing the risk of coccidiosis. In addition, moist litter also promote the growth of other disease agents such as bacteria and fungi.
Sedative Effect of Lemongrass (Cymbopogon nardus) Aromatherapy through Inhalation Route on Mice (Mus musculus) Behavior Surachmat, Hilmy Luqman; Arianto, Eko Fuji; Khairani, Shafia
Veterinary Biomedical and Clinical Journal Vol. 6 No. 2 (2024):
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2024.006.02.3

Abstract

Aromatherapy is an alternative practice in natural medicine that uses essential oil derived from various plants. Essential oil is found in over 17,000 plant species, including lemongrass (Cymbopogon nardus). Lemongrass essential oil contains several active components with potential sedative effects, such as linalool. Therefore, this study aimed to evaluate the potential sedative effect of lemongrass essential oil aromatherapy through inhalation route as an alternative preparation. Mice (Mus musculus) were divided into 5 groups, namely negative and positive control (Diazepam 0.012 mg/kg), as well as treatment 1 (P1, 30-minute exposure), 2 (P2, 60-minute exposure), and 3 (P3, 90-minute exposure). Essential oil of lemongrass was extracted using the distillation method, followed by phytochemical testing. Behavioral observations were carried out using Chimney test method. The results of Chimney test showed that lemongrass aromatherapy had no sedative effect. This result was evident by the insignificant differences (P > 0.05) between negative control groups and both P1 and P3, as well as P1 and P3. Furthermore, P2 showed a potential stimulant effect based on Chimney test results.
Prevalence, Lesion Characteristics, Risk Factors of Scabies Transmission in Cats (Felis catus) at Go Pet Care Animal Clinic (2020-2022) Dara, Sarah Azzahra Dwi; Fauziah, Nisa; Khairani, Shafia
Journal of Parasite Science Vol. 9 No. 1 (2025): Journal of Parasite Science
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jops.v9i1.61622

Abstract

The COVID-19 pandemic (2019-2021) resulted in a surge in pet adoptions, potentially elevating the risk of various diseases in domestic cats, including scabies. Scabies, a highly contagious dermatological condition, is primarily caused by parasitic mites such as Notoedres cati and Sarcoptes scabiei. This study aimed to investigate the prevalence, clinical manifestations, and associated risk factors of scabies in domestic cats at Go Pet Care Animal Clinic in West Bandung Regency over the period from 2020 to 2022. Utilizing a cross-sectional study design, secondary data were extracted from medical records and analyzed using Microsoft Excel and SPSS version 29.0.1.0. A chi-square test was performed with a 95% confidence level (α = 0.05) to assess the statistical significance of the findings. Out of 71 cats diagnosed with scabies, the highest incidence was observed in cats under one year of age (kittens), long-haired breeds, and females. The prevalence of scabies showed a significant increase, rising from 2% to 11.2% over the study period. Common clinical manifestations included alopecia and crusting. Statistical analysis revealed that age was a significant risk factor influencing the prevalence of scabies. These findings underscore the need for heightened awareness and preventive measures for scabies, particularly in younger and long-haired cats.
Malaria and Related Haemosporidian Parasites of Wildlife in Southeast Asia: A Risk for Global Health Khairani, Shafia; Setyowati, Endang Yuni; Krissanti, Ita
Jurnal Medik Veteriner Vol. 8 No. 1 (2025): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol8.iss1.2025.199-222

Abstract

Malaria and related haemosporidian parasites are widespread diseases that can inflict severe harm on both humans and animals. These parasites are protozoans classified within the order Haemosporidia, which encompasses four families: Garniidae, Haemoproteidae, Leucocytozoidae, and Plasmodiidae. The majority of species belong to three primary genera—Haemoproteus, Leucocytozoon, and Plasmodium—which have the capacity to infect a diverse array of animal species, including birds, reptiles, snakes, and mammals. Diagnostic techniques, such as light microscopy and molecular methods like polymerase chain reaction (PCR), have been extensively developed to identify these infections. Despite these advancements, research on the prevalence of malaria in wildlife across Southeast Asia remains sparse. This review article examines the significance of malaria and related haemosporidian parasites in wildlife within Southeast Asia and their potential implications for global human health. A total of 285 articles were reviewed, with 42 qualitative studies being included in this analysis. The majority of these studies were conducted in Malaysia, Indonesia, Thailand, the Philippines, Singapore, Myanmar, Laos, and Cambodia. Among the reviewed studies, 27 out of 42 (64.28%) focused on non-human primates, while 15 out of 42 (35.71%) addressed other wildlife such as birds and bats. Macaca fascicularis (long-tailed macaque) was the primary subject in 18 studies (66.66%), followed by M. nemestrina, Pongo pygmaeus, and various other macaque species and gibbons. In contrast, studies involving other wildlife, including birds and bats, exhibited considerable variability in species and sample sizes, ranging from a minimum of 4 individuals to a maximum of 400 individuals. Molecular diagnostics are predominantly used for non-human primates and other wildlife, as opposed to conventional methods like blood smears. Zoonotic malaria has emerged as a significant concern due to factors such as deforestation, agricultural expansion, and forest fragmentation, which increase human-wildlife interactions and facilitate mosquito breeding, thereby heightening the risk of Plasmodium knowlesi malaria. In summary, malaria and related haemosporidian parasites represent a substantial public health threat in Southeast Asia.
Effect of Citronella (Cymbopogon nardus) Aromatherapy Inhalation on Hematology Profile in Mice (Mus musculus) Shafa Azizah; Eko Fuji Ariyanto; Khairani, Shafia
Veterinary Biomedical and Clinical Journal Vol. 7 No. 1 (2025): Vol. 7 No. 1 2025
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2025.007.01.2

Abstract

Citronella (Cymbopogon nardus) is a widely distributed herbal plant throughout Indonesia, known for its aromatic essential oils that possess various biological properties such as antimicrobial, anti-inflammatory, and insect-repellent effects. Despite its widespread traditional use, limited studies have evaluated the systemic safety profile of citronella essential oil when administered via inhalation, especially its impact on hematological parameters, which are critical indicators of physiological and immune status. This study aimed to investigate the effects of inhaled citronella essential oil on the hematological profile of Swiss webster mice to assess its potential hematotoxicity and systemic safety. Citronella essential oil was extracted using steam-water distillation and characterized through phytochemical screening. Mice were divided into five groups: a negative control, a positive control treated with Diazepam (0.012 mg/kg), and three treatment groups exposed to citronella essential oil vapor for 30 minutes (P1), 60 minutes (P2), and 90 minutes (P3). Each dose consisted of 500 µL of essential oil diluted 1:1 with pyrogen-free water, corresponding approximately to 445 mg of essential oil per administration, with an estimated concentration of about 44.5% w/v based on typical oil density. Hematological parameters, including red and white blood cell counts, hemoglobin concentration, hematocrit, and platelet levels, were analyzed using the Kruskal-Walli’s test. The results showed no statistically significant differences between the citronella-exposed groups and controls, indicating that inhalation exposure at the given dose and duration did not induce hematological toxicity or adverse systemic effects. These findings suggest that citronella essential oil, when administered by inhalation under the tested conditions, is safe in Swiss webster mice and supports its continued use in aromatherapy and related applications. Further studies are recommended to explore long-term effects and other physiological parameters.
ANGKA KEJADIAN DAN KARAKTERISTIK LESI PATOLOGI CALICIVIRUS PADA KUCING (Felis catus) DI VEE VET BANDUNG PERIODE AGUSTUS-SEPTEMBER 2024 Arifah, Kaila Nurul; Khairani, Shafia; Murad, Chrysanti; Felani, Yulita Nurul Hikmah
Jurnal Sain Veteriner Vol 43, No 2 (2025): Agustus
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.101759

Abstract

Feline calicivirus merupakan penyakit akibat virus yang sangat menular pada kucing. Penyakit ini menyerang saluran pernapasan bagian atas. Feline calicivirus memiliki angka morbiditas yang tinggi dengan gejala yang umumnya serupa dengan penyakit lain. Penelitian ini bertujuan untuk mengetahui angka kejadian serta karakteristik lesi patologi feline calicivirus pada kucing di Vee Vet Bandung periode Agustus – September 2024. Metode penelitian ini dilakukan dengan mengambil data langsung kepada seluruh kucing yang datang ke Vee Vet Bandung periode Agustus-September 2024 dengan keluhan lesi pada mulut dan gangguan pernapasan bagian atas. Pengambilan data dilakukan dengan melakukan uji rapid test dan mendokumentasikan lesi untuk mengetahui bentuk serta lokasi lesi pada kucing dengan kriteria yaitu, hasil positif rapid test feline calicivirus, terdapat lesi pada mulut, dan terdapat gangguan pernapasan bagian atas. Selanjutnya, data akan diolah pada microsoft excel yang kemudian akan dibahas secara deskriptif. Hasil penelitian menunjukan bahwa angka kejadian dari feline calicivirus di Vee Vet Bandung periode Agustus-September 2024 tergolong sangat rendah yaitu 0.05%. Hasil tersebut didapatkan dari 4 pasien terdiagnosa feline calicivirus dengan seluruh populasi kucing yang datang sebanyak 722 pasien. Karaktersitik lesi patologi yang muncul pada seluruh kucing terdiagnosis feline calicivirus adalah seluruh kucing memiliki lesi pada mulut berupa ulser kemerahan khususnya pada bagian lidah dan mukosa mulut serta tidak terjadi nekrosis ataupun edema baik itu di wajah atau pawpad.   
PENGOLAHAN SUSU DAN PEMBUATAN SILASE HIJAUAN DI DESA CIBIRU WETAN: STRATEGI MENUJU PENGEMBANGAN TERNAK UNGGUL Khairani, Shafia
DHARMAKARYA: Jurnal Aplikasi Ipteks untuk Masyarakat Vol 13, No 4 (2024): Desember : 2024
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/dharmakarya.v13i4.57970

Abstract

Desa Cibiru Wetan merupakan wilayah yang mayoritas penduduknya bergantung pada sektor peternakan. Namun, manajemen pemeliharaan ternak yang kurang optimal, terutama dalam aspek nutrisi dan pakan, sering kali menyebabkan masalah seperti bloat pada ternak, yang berdampak pada penurunan kualitas dan kuantitas produk ternak, khususnya susu. Selain itu, rendahnya pengetahuan masyarakat terkait pengolahan susu dan kualitas susu yang baik turut menjadi tantangan dalam meningkatkan nilai tambah hasil peternakan. Program Kreativitas Mahasiswa Bidang Pengabdian Masyarakat ini bertujuan untuk memberdayakan masyarakat melalui edukasi dan pendampingan dalam pengolahan susu, peningkatan kualitas susu melalui uji organoleptik dan pasteurisasi, serta pembuatan silase hijauan sebagai solusi atas keterbatasan pakan hijauan berkualitas. Kegiatan dilaksanakan selama tiga bulan dengan tahapan persiapan, pelaksanaan (sosialisasi, edukasi, dan pendampingan), serta evaluasi. Hasil program menunjukkan peningkatan pengetahuan masyarakat terkait nutrisi ternak dan pembuatan silase hijauan, serta terkait pasteurisasi dan kualitas susu. Post-test mengungkapkan bahwa seluruh peserta memahami konsep nutrisi pakan fermentasi (silase hijauan) dan pengolahan susu berkualitas. Program ini diharapkan memberikan dampak berkelanjutan dalam meningkatkan produktivitas dan kualitas hasil peternakan di Desa Cibiru Wetan, sekaligus mendukung kesehatan masyarakat melalui pengelolaan ternak yang lebih baik.Cibiru Wetan Village is an area where the majority of the population depends on the livestock sector. However, suboptimal livestock management, particularly in terms of nutrition and feed, often leads to problems such as bloat in livestock, resulting in a decline in the quality and quantity of livestock products, especially milk. Additionally, the community's limited knowledge of milk processing and good milk quality presents a challenge in enhancing the added value of livestock products. The Student Creativity Program in Community Service aims to empower the community through education and assistance in milk processing, improving milk quality through organoleptic tests and pasteurization, and producing green silage as a solution to the limited availability of quality green fodder. The activity was carried out over three months, with stages of preparation, implementation (socialization, education, and assistance), and evaluation. The results of the program showed an increase in community knowledge regarding livestock nutrition and the production of green silage, as well as pasteurization and milk quality. The post-test revealed that all participants understood the concepts of fermented feed nutrition (green silage) and quality milk processing. This program is expected to have a sustainable impact on increasing the productivity and quality of livestock products in Cibiru Wetan Village, while supporting public health through improved livestock management. 
Prevalence and Pathological Lesions of Dermatophytosis in Cats (Felis catus) at the Animal Health Center in Cimahi: August-September 2023 Fauziyah, Sri Nur Farah; Dewi, Intan Mauli Warma; Khairani, Shafia
Journal of Parasite Science Vol. 9 No. 2 (2025): Journal of Parasite Science
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jops.v9i2.61623

Abstract

Dermatophytosis is a zoonotic fungal infection affecting the superficial skin layer. characterized by circular lesions commonly referred to as "ringworm." This condition has been recorded as the most frequently occurring ailment at the Animal Health Center in Cimahi. This study aims to determine the prevalence and characteristics of dermatophytosis lesions in cats at the Animal Health Center in Cimahi during the period of August-September 2023. Samples were collected based on physical examinations and supporting diagnostics. such as Wood's lamp inspection. on animals suspected of having dermatophytosis. The results revealed that the prevalence of dermatophytosis in cats during the specified period was 10.5%. with 91 cases out of 864 patients. The most common lesions observed included epidermal collars with scales. crusts. erythema. hyperpigmentation. and alopecia. totaling 613 lesions from 91 patients. The highest number of lesions was found in the dorsal body region. with a total of 115 lesions. Predisposing factors such as age. sex. and breed indicated that dermatophytosis was most prevalent in cats aged less than 6 months (38 cats. 41.7%). female cats (46 cats. 50.5%). and domestic breed cats (40 cats. 43.9%). This study contributes valuable epidemiological data on dermatophytosis in animals in Indonesia.