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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Ilmu Kefarmasian Indonesia Jurnal Pengabdian Masyarakat Indonesia Pharmaceutical And Biomedical Sciences Journal (PBSJ) Pharmaceutical Sciences and Research (PSR) Sciences of Pharmacy Abdi Implementasi Pancasila: Jurnal Pengabdian kepada Masyarakat
Reise Manninda
Fakultas Farmasi, Universitas Pancasila, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Control & Systems Engineering Education Engineering Environmental Science Health Professions Medicine & Pharmacology Public Health Social Sciences

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Evaluation of the rationality of drugs use inpatient patients with type 2 diabetes mellitus of 2023 at Hospital Y Depok Khairani, Sondang; Manninda, Reise; Wijayanti, Bitya Aulia
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i1.1694

Abstract

Diabetes mellitus is a chronic disease caused by failure to control blood glucose levels. Type 2 Diabetes Mellitus (T2DM) is a condition of hyperglycemia caused by the failure of insulin to maintain balanced blood sugar levels. If T2DM is not treated it will cause complications. One way to control T2DM is the rational use of antidiabetic drugs. This study aims to look at the demographic data of inpatients with T2DM, patterns of drug use, rationality for drug use, and the relationship between the rationality of drug use and therapeutic outcomes in inpatients with T2DM at Hospital Y Depok for the period 2023. The outcome evaluated is a random blood sugar test. The research method was carried out descriptively and inferentially with a cross-sectional design. There were 122 samples that met the inclusion criteria, women predominantly suffered from type 2 diabetes mellitus (50.89%). The most common age range was 46-65 years (64.56%). As many as 84.31% of patients used the JKN payment method. The most widely used class of type 2 diabetes mellitus medication is insulin. In evaluating the rationality of using type 2 diabetes mellitus drugs, the rationality results were 99.49% correct drug, 100% correct dose, and 98.73% correct administration. The results of statistical tests show that there is a correlation between the rationality of drug use and clinical outcomes p-value 0.001.
The factors related to medication adherence in outpatient hypertension patients at Leuwiliang Hospital, Bogor Regency Nurita Andayani; Luthfiah Ratikasari; Rira Noviarianti; Manninda, Reise; Fauzi, Hamid
Pharmaciana Vol. 15 No. 3 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i3.30968

Abstract

Hypertension is the leading cause of cardiovascular disease in the world and contributes to 10 million deaths every year. Non-adherence is an important factor in uncontrolled hypertension, thus leading to reasons for non-adherence to treatment or medication. This study aims to identify the factors related to adherence to treatment for outpatients at Leuwiliang Regional Hospital, Bogor Regency. This study used a quantitative descriptive approach with cross-sectional data. The study population consisted of all outpatient hypertension patients at Leuwiliang Regional Hospital in 2023. Sampling used the purposive sampling technique with a sample of 312 patients. Data were analyzed descriptively and analytically with the Spearman-rho correlation test. The results showed that the level of adherence among patients with hypertension was mostly moderate (39.7%). Treatment adherence was related to self-motivation (p-value = 0.000), but the relationship was weak, with a correlation coefficient of r = 0.258. The level of knowledge, family support, and role of health workers did not have a significant relationship to the level of adherence. The correlation value between the level of knowledge and the level of adherence had a negative relationship, although it was not significant. These might be due to knowledge, family support, and the role of health workers might not directly influence the level of compliance but might be supported by other variables such as age, gender, education, patient access to health facilities, patient economic level, length of hypertension, economic profile, and patient hypertension level (length of hypertension), but in this study no relationship analysis was carried out.
Analysis of Antibiotic Therapy Accuracy and Drug Interaction in Pneumonia Inpatients at The Islamic Hospital Jakarta Cempaka Putih Khairani, Sondang; Manninda, Reise; Ariani, Lusiana; Iskandar, Benni; Hidayati, Nabila Nur
Sciences of Pharmacy Volume 4 Issue 4
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0404456

Abstract

Polypharmacy may increase the risk of drug interactions affecting toxicity and therapeutic efficacy in pneumonia patients. This study aimed to analyse evaluation of pneumonia management, polypharmacy, relationship between polypharmacy and occurrence of drug-drug interactions, and relationship between drug-drug interactions and length of hospital stay of pneumonia patients. The study design used a quantitative descriptive approach with cross-sectional and retrospective data collection and a total sample of 113 samples that met the criteria. Analyses were performed using Spearman's rho correlation test to assess the association of polypharmacy with drug interactions, and the association of drug interactions with length of hospital stay. Medication accuracy was measured using PDPI (The Indonesian Lung Doctors Assosiaciation) guidelines, drug interactions using drugs.com and/or Medscape.com. Results showed 59.29% of patients were female, with the majority aged over 65 (55.65%). Most patients (91.15%) paid with BPJS, 62.61% were hospitalised for 1-5 days and 81.74% had comorbidities. Treatment accuracy in this study was 49.56%. 106 drug interactions were identified in a total of 226 cases. 66% of the interactions were pharmacodynamic with moderate severity (79%), such as the interaction between combivent and ondansetron. Mild pharmacokinetic interactions were common, especially between ranitidine and paracetamol (22 cases). There is a correlation between polypharmacy and drug interactions with a p-value 0.000 and there is a correlation between the number of drug interactions and length of hospitalisation with p-value 0.000. Conclusion of this study is polypharmacy increases the risk of drug interactions and affects the length of hospital stay in pneumonia patients.
Edukasi Keamanan Pangan dan Tanaman Herbal Pada MI Avia Scientific Manninda, Reise; Andayani, Nurita; Desmiaty, Yesi; Heryani, Aulia; Fatmawati, Yuli; Margono, Adi Dwi; Yolanda; Puspita, Rita; Endeline, Hanna Arystha; Jemmima, Jeanice; Viyoli, Divo; Ramadhani, Sasti Fauziyah
Abdi Implementasi Pancasila:Jurnal Pengabdian kepada Masyarakat Vol 5 No 2 (2025): on progress
Publisher : Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/8em26c38

Abstract

The food safety of schoolchildren's snacks is the most important thing in improving the quality and nutrition of snacks consumed to enhance the quality of student's health. Despite ongoing efforts, many snacks still contain biological, chemical, and physical hazards, posing long-term health risks. This community service initiative focuses on using medicinal plants like tomatoes and oranges. These plants can be transformed into healthy, attractive snack alternatives such as foods and drinks rich in vitamins E, C and antioxidants. The project aims to educate students about snack food additives and the benefits of medicinal plants. Outreach activities include video presentations on snack safety and the detection of hazards. The results showed that their knowledge before the educational intervention was 72,16% and it increased to 75,69% after the intervention, resulting in a 3,53% improvement. The result of the food samples tested, which were brought by the students, also showed negative results, indicating no harmful substances were present. This counseling activity went well and increased students' awareness and understanding of the importance of choosing safe snacks. It is hoped that this activity will positively impact students' daily consumption and help them choose food more wisely.
Co-Authors Ade Rosanti Andayani, Nurita Anggriani, Yusi Annisa, Rifka Ariani, Lusiana Astrid Kartika Sari BENNI ISKANDAR Endeline, Hanna Arystha Evy Yunihastuti Fauzi, Hamid Fauzia Noprima Okta Fitri Nurhayati Fredrick D. Purba Fredrick Dermawan Purba Heryani, Aulia Hidayati, Nabila Nur Jemmima, Jeanice Kurnia, Mala Luthfiah Ratikasari Margono, Adi Dwi Mita Restinia Mulatsari, Esti Nurita Andayani Puspita, Rita Raharjo, Lalu Joko Ramadhani, Sasti Fauziyah Rifka Annisa Rira Noviarianti Rosanti, Ade S.Farm., M.Farm., Apt, Sondang Khairani Sarah, Mutia Shirly Kumala Tarsinah Tarsinah Tarsinah, Tarsinah Viyoli, Divo Widodo, Akhmad Fajri Wijayanti, Bitya Aulia Yesi Desmiaty, Yesi Yolanda Yuli Fatmawati Yulia Trisna Yulia Trisna, Yulia Yusi Anggriani Yusi Anggriani