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A Insights from literature analysis : optimal sunscreen use decreases Melasma incidence in women living in tropical climates Damayanti, Lina; Pradini, Astri; Salsabila, Mitha
ACTA Medical Health Sciences Vol. 2 No. 3 (2024): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Melasma is a hyperpigmented patch that is generally found on the face, especiallyon the cheeks, chin, upper lip, and can extend to the neck. The color of hyperpigmentation in melasma varies, generally from light brown to black with an irregular shape. Melasma is often found in countries with tropical climates with skin types III-V. This happens because countries with these climates are exposed to more sunlight. To prevent melasma, it is recommended to use sunscreen to reduce excessive UV exposure to the skin. It is important to use sunscreen optimally in order to reduce the incidence of melasma. The effect of excessive UV exposure to skin, including melasma, can be reduced by applying sunscreen on the regular basis. This literature review used four databases (Google scholar, PUBMED, NCBI and PERDOSKI) and relevant keywords such as "melasma" and "sunscreen" to find the source of articles published in 2010 to 2022. A total of 142 articles in Indonesian and English were found. After selecting based on inclusion and exclusion criteria, 14 relevant articles were obtained and will be discussed in this literature review. The result of this literature review show a significant relationship between optimal use of sunscreen and the incidence of melasma in women from countries with tropical climates, especially in Asia. Melasma is most commonly found in women with Fitzpatrick skin types III-V and more likely to occur between ages 25-60 years. Patients with melasma who used sunscreen optimally, by applying it every 2 hours, showed a decrease in the degree of severity of melasma compared to those who did not repeat the use of sunscreen. The conclusion can be strengthened more straightforward. For example, applying sunscreen every 2h can significantly decrease the incidence of melasma. DOI : 10.35990/amhs.v2n3.p148-156 REFERENCES Rodrigues M, Pandya AG. Hypermelanoses. In: Kang S, Amagai M, Bruckner AL, Enk AH, Margolis DJ, McMichael AJ, et al, editors. Fitzpatrick’s Dermatology. 9th ed. New York: McGraw Hill; 2019. p. 1379-81. Handel AC, Miot LDB, Miot HA. Melasma: a clinical and epidemiological review. An Bras Dermato. 2014;5:772. Sarkar R, Arora P, Garg VK, Sonthalia S, Gokhale N. Melasma Update. Indian Dermatology Online Journal. 2014;5(4):426. Apriliyani PY. Hubungan Antara Pemakaian Tabir Surya Dengan Derajat Keparahan Melasma (Skor MASI) Pada Wanita di Kec. Grogol-Sukoharjo. Surakarta: Fakultas Kedokteran Universitas Muhammadiyah Surakarta; 2017. Shankar KDSR, Somani VK, Kohli M, Sharad J, Ganjoo A, Kandhari S, et al. A cross-sectional, multicentric clinico-epidemiological study of melasma in India. Dermatologic Therapy. 2014;3:71-81. Purba RA. Gambaran Faktor-Faktor Risiko Timbulnya Melasma di Poliklinik Kulit dan Kelamin RSU Royal Prima dan Murni Teguh Memorial Hospital Kota Medan Pada Bulan Desember 2018-Januari 2019. Medan: Fakultas Kedokteran Universitas HKBP Nommesen Medan; 2019. Waskita TW. Hubungan antara riwayat pemakaian tabir surya dengan derajat keparahan melasma. Cimahi: Fakultas Kedokteran Universitas Jenderal Achmad Yani; 2018. Umborowati MA, Rahmadewi. Studi Retrospektif: Diagnosis dan Terapi Pasien Melasma. Berkala Ilmu Kesehatan Kulit & Kelamin. 2014;26:56-61. Krupa S, Devasthanam SR, et al. A cross-sectional, multicentric clinico-epidemiological study of melasma in India. 2014;4.1:71-81. Rattananukrom T, Suchonwanit P, Thadanipon K, Vachiramon V. A Comparative Study of Dermatoscopic Features of Melasma and Hori's Nevus in Asian Patients. J Clin Aesthet Dermatol. 2022;15(3):16-20. Bhattarai S, Pradhan K, Sharma S, Rajouria EA. Clinical patterns and epidemiological characteristics of melasma in a tertiary care hospital of Nepal. Pigment International. 2017;4(1):35. Wu MX, Antony R, Mayrovitz HN. Melasma: A Condition of Asian Skin. Cureus. 2021;13(4). Jha AK, Karki S. Vitiligo and melasma: a psychosocial-cosmetic challenge in context of south Asian countries. J Pigment Disord. 2015. Harumi O, Goh CL. The effect of melasma on the quality of life in a sample of women living in Singapore. The Journal of Clinical and Aesthetic Dermatology. 2016 Jan;9(1):21. Setyawati NK. Insiden dan Profil Melasma di Rumah Sakit Umum Pusat Sanglah Denpasar Periode Januari 2014 Sampai Desember 2014. E-Jurnal Medika Udayana. 2019 Apr 18;8(2). Lahida SP. Hubungan riwayat pemakaian tabir surya dengan kejadian melasma pada wanita usia 25-45 tahun. Jakarta: Trisakti; 2018. Prabawaningrum CD. Hubungan Riwayat Pemakaian Tabir Surya dengan Kejadian Melasma. Surakarta: Fakultas Kedokteran Universitas Negeri Surakarta; 2015. Fatima S, Braunberger T, Mohammad TF, Kohli I, Hamzavi IH. The Role of Sunscreen in Melasma and Postinflammatory Hyperpigmentation. Indian Journal of Dermatology. 2020;65(1):5-10. Sarkar R, Ghunawat S, Narang I, Verma SK, Garg VK, Dua R. Role of broad‐spectrum sunscreen alone in the improvement of melasma area severity index (MASI) and Melasma Quality of Life Index in melasma. Journal of Cosmetic Dermatology. 2019;18(4):1066-1073. Maymone MB, Neamah HH, Wirya SA, Patzelt NM, Zancanaro PQ, Vashi NA. Sun-protective behaviors in patients with cutaneous hyperpigmentation: A cross-sectional study. Journal of the American Academy of Dermatology. 2017;76(5):841-846.
Bantuan Alat Pelindung Diri Penanganan Pasien Covid-19 di Puskesmas Kota Cimahi Triningtyas, Anastasia Yani; Sovia, Evi; Pradini, Astri; Nurlaela, Lutfhi; Meria, Rr. Desire; Juliastuti, Henny; Susanti, Anita Liliana
Jurnal Abdimas Kartika Wijayakusuma Vol 2 No 1 (2021): Jurnal Abdimas Kartika Wijayakusuma
Publisher : LPPM Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (491.47 KB) | DOI: 10.26874/jakw.v2i1.96

Abstract

Abstrak: Sejak WHO mengumumkan keadaan pandemi wabah virus Corona baru atau Coronavirus Disease-19 (COVID-19), hingga saat ini penularan virus Corona di Indonesia terus bertambah. Upaya untuk menangani pandemi COVID-19, memerlukan kesiapan dan tanggapan yang bersifat kritis seperti memperlengkapi tenaga kesehatan dengan informasi, prosedur, dan alat yang penting agar dapat bekerja dengan aman dan efektif. Puskesmas merupakan ujung tombak pelayanan kesehatan di masyarakat. Tenaga kesehatan berisiko lebih tinggi terinfeksi COVID-19 dalam upayanya melindungi masyarakat lebih luas. Dalam penanganan COVID-19, penggunaan alat pelindung diri (APD) oleh tenaga kesehatan yang terlibat langsung dalam penanganan pasien merupakan hal yang sangat penting. Sebagian besar APD hanya bisa digunakan satu kali dan sebagian kecil bisa digunakan lagi setelah melalui proses sterilisasi. Kota Cimahi merupakan salah satu kota dengan peningkatan kejadian penderita COVID-19 yang sangat pesat. Hal ini menyebabkan tingginya kebutuhan APD dalam jumlah yang memadai dan berkelanjutan di puskesmas. Universitas Jenderal Achmad Yani menyadari pentingnya melindungi tenaga fasilitas pelayanan kesehatan khususnya mereka yang bertugas di puskesmas sebagai garda terdepan. Kegiatan pengabdian kepada masyarakat ini bertujuan memberikan bantuan APD penanganan COVID-19 di Puskesmas-puskesmas yang ada di Kota Cimahi. Kata kunci: Alat Pelindung Diri, COVID-19, Puskesmas
RASIO VISCERAL FAT TERHADAP BODY FAT PERCENTAGE DAN KORELASI LEMAH DENGAN KADAR HIGH DENSITY LIPOPROTEIN Susanti, Anita Liliana; Pratiwi, Siska Telly; Mardliyah, Emma; Ratwita, Welly; Mutiara, Dinar; Septiadi, Endry; Pradini, Astri; Sa'adah, Hindun
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 7 No 4 (2024): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

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Abstract

Pemeriksaan profil lipid dari serum sampai saat ini masih merupakan pemeriksaan yang digunakan untuk menentukan risiko terjadinya penyakit kardiovaskular di kemudian hari. Kadar High Density Lipoprotein (HDL) menggambarkan lipid yang berperan dalam mencegah terjadinya penyakit kardiovaskuler. Adipositas dalam pemeriksaan komposisi tubuh menggambarkan akumulasi lipid dalam jaringan, dan terdiri atas persentase lemak tubuh dan lemak visceral. Penelitian ini mempelajari korelasi antara kadar HDL serum dengan adipositas jaringan. Subyek penelitian merupakan subyek yang sehat, merupakan karyawan dari suatu institusi pendidikan dengan tingkat aktivitas fisik yang serupa. Pemeriksaan komposisi tubuh dilakukan dengan metode Bioimpedanceanalysis (BIA). Pemeriksaan kadar HDL dilakukan dari serum puasa dengan metode enzimatik kolorimetrik. Analisis korelasi dilakukan dengan Spearman correlation test dengan menggunakan program Statistical Package for Social Sciences (SPSS). Hasil penelitian menunjukkan bahwa subyek penelitian memiliki kadar HDL dalam kategori normal. Persentase lemak tubuh dan lemak visceral sebagian besar subyek penelitian berada dalam kategori normal, tinggi, dan sangat tinggi. Median kadar HDL adalah 49,00 mg/dL. Median dari rasio lemak visceral dan lemak tubuh total adalah 0,40. Korelasi antara kadar HDL dan rasio lemak visceral dan lemak tubuh total bermakna (P= 0,027) dengan koefisien korelasi sebesar - 0,4. Penelitian ini menunjukkan bahwa terdapat korelasi lemah antara adipositas jaringan yang ditunjukkan dengan rasio lemak viseral terhadap persentase lemak tubuh, dengan parameter lipid serum yaitu kadar HDL. Kata kunci : adipositas, bioimpedance, body fat, HDL, visceral fat DOI : 10.35990/mk.v7n4.p387-397
The effect of celery ethanol extract (Apium graveolens l.) against fatty liver in rat model of hyperlipidemia Trimurtini, Indarti; Pradini, Astri; Vita Nirmala Sari, Vania; Sovia, Evi
ACTA Medical Health Sciences Vol. 1 No. 3 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Fatty liver is a disorder of liver characterized by the accumulation of fat liver cells. The incidence of fatty liver in Indonesia is 30%. Fatty liver can be caused by hyperlipidemia. Hyperlipidemia triggers an increase of oxidative stress that leads to fatty liver. Treatment is usually carried out using statins, but long-term consumption of statin may lead to several side effects. Other treatment that can lower cholesterol levels traditionally is celery. This study aimed to determine the effect of ethanol extract of celery on the microscopic appearance of the liver induced by hypercholesterolemia in experimental rats. This was an posttest control group experimental on 25 rats that were divided into 5 groups: negative control group, positive control group, and three (3) treatment groups. Each treatment group was given a high-fat diet for 14 days, followed by a provision of high-fat diet with different celery extract doses of 37.5 mg/KgBW/day, 75 mg/KgBW/day, and 150 mg/KgBW/day. After the treatment completed, the rats were sacrificed and dissected, and their liver was for histopathological preparations. Data on the in the average fat score between the control group and the three treatment groups were collected and analyzed using one way ANOVA if they were normally distributed with the Kruskal Wallis test as the alternative test. To determine whether there was a significant difference between two treatment groups, a post-hoc statistical test was performed. A significant change was observed in the histological presentations of the liver between control and treatment groups (p <0.5). There was a marked improvement of cytoplasm, sinusoid and cell nucleus in the treatment groups compared to positive control group with a dose of 37.5 mg/KgBW/day as the most effective celery ethanol extract to improve liver fat due to fat accumulation. DOI : 10.35990/amhs.v1n3.p121-127 REFERENCES Wulandari RL, Susilowati S, Murnik A. Pengaruh kombinasi ekstrak etanol daun sirsak (Annona muricata) dan simvastatin terhadap kadar kolesterol total dan Low Density Lipoprotein (LDL) tikus yang diinduksi pakan tinggi lemak. Hiperkolesterol, Ekstrak Etanol Daun Sirsak, Koles Total LDL. 2015;(LDL):24–32. Syafitri V, Arnelis A, Efrida E. Gambaran profil lipid pasien perlemakan hati non-alkoholik. J Kesehat Andalas. 2015;4(1):274–8. Yao YS, Li TD, Zeng ZH. Mechanisms underlying direct actions of hyperlipidemia on myocardium: An updated review. Lipids Health Dis. 2020;19(1):1–6. Setiawan SI, Kurniawan J, Bhakti Asih R, Tangerang K, Hepatobilier D. Pilihan tatalaksana penyakit perlemakan hati non-alkohol (Non-Alcoholic Fatty Liver Disease/NAFLD). Cermin Dunia Kedokt. 2021;48(3):173–5. Chitturi S, Farrell GC, Hashimoto E, Saibara T, Lau GKK, Sollano JD. Non-alcoholic fatty liver disease in the Asia-Pacific region: Definitions and overview of proposed guidelines. J Gastroenterol Hepatol. 2007;22(6):778–87. Neuschwander-Tetri BA. Non-alcoholic fatty liver disease. BMC Med. 2017;15(1):1–6. Oktavianie DA. Hiperkolesterolemia, benalu mangga, trigliserida, histopatologi hepar. Laporan Penelitian. Fakultas Kedokteran Universitas Halu Oleo; 2020:1–8. Sanchez P, Chetty G, Sarkar P. Not the typical winter cough. BMJ Case Rep. 2009. Guyton AC, Hall JE. Buku Ajar Fisiologi Kedokteran. Edisi ke-12. Jakarta: ECG; 2006. Hariadini AL, Sidharta B, Ebtavanny TG, Minanga EP. Hubungan tingkat pengetahuan dan ketepatan penggunaan obat simvastatin pada pasien hiperkolesterolemia di apotek kota Malang. Pharm J Indones. 2020;5(2):91–6. Hartono H, Handayani S. Pengaruh pemberian seledri (Apium graveolens) terhadap penurunan hiperkolesterolemia pada lansia di Panti Wreda Darma Bhakti Kasih Surakarta. Interes J Ilmu Kesehat. 2017;6(2):217–23. Handayani L, Widowati L. Analisis lanjut pemanfaatan empiris ramuan seledri (Apium graveolens) oleh penyehat tradisional. J Kefarmasian Indones. 2020;31–41. Yao Y, Sang W, Zhou M, Ren G. Phenolic composition and antioxidant activities of 11 celery cultivars. J Food Sci. 2010;75(1):9–13. Susanti R, Yuniastuti A. Efektivitas ekstrak tanin seledri terhadap profil lipid tikus putih hiperkolesterolemia. Life Sci. 2012;1(2). Rusdiana T. Telaah tanaman seledri (Apium graveolens) sebagai sumber bahan alam berpotensi tinggi dalam upaya promotif kesehatan. Indones Nat Res Pharm J. 2018;3(1):1–8. Priatna RD. Efek anti-hiperkolesterolemia ekstrak etanol daging buah plum (Prunus salicina) pada tikus jantan galur Wistar yang diinduksi diet tinggi lemak. Tesis. Universitas Jenderal Achmad Yani; 2020. Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41(6):1313–21. Badan Pengawas Obat dan Makanan Republik Indonesia. Acuan Sediaan Herbal. BPOM RI; 2020:1–58. Sunarjono H. Bertanam Sayuran Daun & Umbi. Jakarta: Penebar Swadaya Grup; 2018. Pujiwidodo D. Formularium Obat Herbal Asli Indonesia. Vol. III. Jakarta: Kementerian Kesehatan RI; 2016.