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All Journal Journal of Case Reports in Dental Medicine Jurnal Ilmiah Kesehatan (JIKA) Neurona Ophthalmologica Indonesiana
Goysal, Yudy
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Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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VALIDITAS MICHIGAN NEUROPATHY SCREENING INSTRUMENT VERSI BAHASA INDONESIA DALAM MENDETEKSI POLINEUROPATI DISTAL SIMETRIS DIABETIKA Bintang, Andi Kurnia; Aulina, Susi; Goysal, Yudy; Amran, Muhammad Yunus; Hamid, Firdaus; Setiawan, Denise Dewanto
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 40 No 3 (2024): Volume 40, No 3 - Juni 2024
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v40i3.436

Abstract

Introduction: Distal Symmetric Polyneuropathy (DSPN) is the most common neuropathy subtype found in Diabetes Mellitus (DM) patients. Early screening is important to prevent complications. Michigan Neuropathy Screening Instrument (MNSI) was created in 1994 as an alternative screening tool for diabetic neuropathy. This instrument has not been validated in Indonesia. Aim: Assess validity and reliability of Indonesian version of MNSI in detecting diabetic DSPN. Methods: This cross-sectional study was done in Wahidin Sudirohusodo hospital, Makassar in December 2021-June 2022. Indonesian version of MNSI and Nerve Conduction Studies (NCS) was applied to subjects. Statistics were performed with Statistical Package for the Social Sciences (SPSS) version 25. Study protocol was approved by Health Research Ethics Committee, Faculty of Medicine, Hasanuddin University. Results: 102 subjects were eligible and divided into DM with DSPN (n=60) and DM without DSPN (n=42). Significant differences were found in age, body mass index, duration of DM diagnosis, treatment, HbA1c, Indonesian version of MNSI part B, and all NCS parameters (p<0,05). Area Under Curve (AUC) of part B was bigger than A (0,942 vs 0,606). Cut-off >=2,5 of part B had sensitivity, specificity, Positive Predictive Value (PPV), and Negative Predictive Value (NPV) of 95,0%, 90,5%, 93,4%, and 92,7%, respectively. Discussion: Cut-off >=2,5 for Indonesian version of MNSI part B was considered optimal. EMNG was recommended for DM patients with part B score >=2,5. Conclusion: Indonesian version of MNSI is a valid and reliable instrument to detect DSPN in Indonesian population. Keywords: diabetic neuropathy, DSPN, Indonesia, MNSI
Type 1 Arnold Chiari Malformation With Syringomyelia: A Case Report Akbar, Muhammad; Armalia, Armalia; Tammasse, Jumraini; Goysal, Yudy; Basri, Muhammad I
Journal of Case Reports in Dental Medicine Vol 3, No 3 (2021)
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jcrdm.v3i3.164

Abstract

Objective: Arnold Chiari Malformation is a pathological herniation of the hindbrain through the foramen magnum into the cervical canal, characterized by herniation of the inferior cerebellar tonsils of 3-5 mm 30-70% accompanied by syringomyelia.Methods: This case presents a 16-year-old woman who came to the Neurophysiology Section of  Wahidin Sudirohusodo Hospital with complaints of weakness and numbness in her left arm since last year. It all started with pain in the back of the head and neck after a heavy sneeze three years ago, and since then, the pain has been inconsistent. The patient has gone to the doctor and was given medication, but his symptoms are not improving. Clinical manifestations get worse after the patient uses a computer or mobile phone. Physical examination revealed atrophy of the thenar and hypothenar muscles and sensory dissociation in the left arm's 5th cervical to a first thoracic dermatome. NCV and F-wave examination showed no signs of radiculopathy, plexopathy, or neuropathy. Furthermore, cervical magnetic resonance imaging (MRI) showed Arnold Chiari Malformation Type-1 with syringomyelia extending from cervical spinal cord segment-2 to thoracic-1.Result: This patient was diagnosed based on history, physical examination, nerve conduction study, and MRI spine. There was no clinical improvement after therapy.Conclusion: The clinical picture of Arnold Chiari Malformation Type-1 is so varied that it requires detailed information to diagnose.
PROFIL KLINIS DAN NEUROIMAGING PASIEN CAROTID CAVERNOUS FISTULA DI RUMAH SAKIT WAHIDIN SUDIROHUSODO MAKASSAR Ardhany, Andri; GOYSAL, YUDY
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 41 No 1 (2024): Vol 41 No 1 (2024): Volume 41, No 1 - Desember 2024
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v41i1.596

Abstract

Introduction: Carotid cavernous fistula (CCF) is a rare abnormal connection between the carotid artery and the cavernous sinus. Based on its etiology, CCF is divided into traumatic and spontaneous types. CCF presents with varied clinical findings and neuroimaging features. Diagnosis is established based on clinical findings and neuroimaging characteristics. Objective: This study aims to provide a descriptive overview of clinical profile and neuroimaging of CCF patients at Wahidin Sudirohusodo Hospital, Makassar. Method: This descriptive study retrospectively collected data from medical records of Wahidin Sudirohusodo Hospital, Makassar, from January 2023 to March 2024, using total sampling method. Results: A total of 25 subjects meeting the criteria were obtained. The mean age was 33.08±15.37 years, predominantly male (76%). The duration of symptoms was mostly >1 month (88%). Trauma was the most common etiology (76%). Unilateral lateralization was most frequent (84%). The most common symptoms and signs were proptosis (80%), conjunctival injection (60%), and headache (52%). Cranial nerve VI involvement was most frequent (52%). All subjects had direct CCF anatomical characteristics. Imaging features included dilated superior ophthalmic vein (92%), proptosis (76%), and cavernous sinus enlargement (36%). Discussion: Traumatic etiology was more common than spontaneous in CCF, consistent with other studies finding traumatic etiology most prevalent in direct CCF patients. Symptoms and signs such as proptosis, conjunctival injection, headache, and imaging features like dilated superior ophthalmic vein, proptosis, and cavernous sinus enlargement on CT scan or MRI suggest CCF. Keywords: Carotid-Cavernous Fistula, Proptosis, Cavernous Sinus
Neuromuscular Taping Decompression Technique in Diabetic Painful Polyneuropathy: Impact on Pain Intensity Harun Muchsin, Achmad; Blow, David; Goysal, Yudy; Wuysang, Audry Devisanty; Tammasse, Jumraini; Bahar, Ashari; Zainuddin, Andi Alfian; Walenna, Nirwana Fitriani
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 41 No 3 (2025): Vol 41 No 3 (2024): Volume 41, No 3 - Juni 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v41i3.679

Abstract

Background: This study aimed to evaluate the effects of neuromuscular taping decompression technique (NMT) on modifying pain scale in diabetic patients with painful distal symmetrical polyneuropathy (DSPN) at Wahidin Sudirohusodo Hospital, Makassar, Indonesia. Using a pure experimental design with a pre-test and post-test control group method, 30 patients were included: 15 in the treatment group and 15 in the control group. The treatment group received decompression NMT on the dorsal and plantar aspects of the foot twice a week for four weeks, along with vitamin B complex supplementation. The control group received only vitamin B complex. Result: The Mann-Whitney test showed significant improvement (p <0.05) in the pain scale of the treatment group on day 28, with the Numeric Pain Rating Scale (NPRS) score being lower than that of the control group. Conclusion: This study demonstrated the significant pain-reducing effect of NMT in DSPN patients. The combination of vitamin B1, B6, and B12 supplementation with 8 NMT sessions over 28 days reduced pain to 0 on the NPRS scale. Treatment twice a week for 4 weeks, alongside vitamin B, led to near-zero pain, with pain-free results expected after 5 treatments over 17 days. NMT combined with vitamin B reduced pain approximately 2 times faster than vitamin B alone. Keywords: Diabetic Painful Distal Symmetrical Polyneuropathy, DSPN, Diabetic Neuropathic Pain, Neuromuscular Taping, NMT
INTERNUCLEAR OPHTHALMOPLEGIA IN MULTIPLE SCLEROSIS PATIENT Tirkal, Fahrian; Mansyur, Yunita; Umar, Batari Todja; Goysal, Yudy; Baan, Junus
Majalah Oftalmologi Indonesia Vol 50 No 2 (2024): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v50i2.101627

Abstract

Introduction: Internuclear ophthalmoplegia (INO) characterized by impaired adduction of the affected eye caused by a lesion in the medial longitudinal fasciculus (MLF). The common cause of INO is demyelinating disease including multiple sclerosis. INO arguably the most discrete localizing sign in medicine, has considerable value in predicting multiple sclerosis. Due to its high spatial resolution, MRI has allowed us to depict in vivo the anatomic organization of the human oculomotor nerve complex, the MLF, and related structures in the brainstem. Case Report: A 48-year-old female presented with blurred vision of both eyes for 2 weeks, but then slowly resolved. Best corrected visual acuity presentation on both eyes were 20/20 with normal intraocular pressure (IOP). Adduction deficit observed on the left eye with no nystagmus. Convergence are not impaired in both eyes. Anterior segments was normal except minimal lens cloudiness in both eyes. Funduscopic examination result also within normal limit. Patient had undergone Computerised Tomography (CT-Scan) and the result was normal, no ischemic area or Space occupied lesion (SOL) or intracranial bleeding were found. Brain MRI showed bilateral optic perineuritis and multiple lesion in bilateral frontoparietalis and in the left side of the pons suggested multiple sclerosis. Discussion: Impairment of adduction movement on the patient’s left eye caused by demyelinating plaque related multiple sclerosis on the left side of the pons as shown MRI imaging. Management in this patient is based on the underlying condition. Conclusion: Internuclear ophthalmoplegia in this cases maybe caused by lesion in the medial longitudinal fasciculus could be related with multiple sclerosis.
Comparison of Giving Mecobalamin Supplements to Improve the Severity of Painful Diabetic Neuropathy Irsyadat, Andi Muhammad; Aulina, Susi; Goysal, Yudy; Zainuddin, Andi Alfian; Lotisna, Mimi; Amran, Muhammad Yunus
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 3 (2024): Volume 6 Nomor 3 Desember 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i3.874

Abstract

Diabetic Painful Neuropathy (DPN) is caused by the progressive loss of nerve fibers due to hyperglycemia, oxidative stress, andhomocysteinemia. Mecobalamin supplementation has shown potential in improving peripheral neuropathy symptoms by enhancing nerve conduction and alleviating neuropathic pain. However, its efficacy data remains limited. This research to investigated the effect of mecobalamin supplementation on the severity of Painful Diabetic Neuropathy in type 2 diabetes mellitus patients. This research is a non-randomized clinical trial, 16 patients were given 500 ?g of intramuscular Mecobalamin 8 times over 30 days (n=8) and 5 times over 10 days (n=8). Subjects underwent measurements VAS, TSS, BDNC and ENMG before and after intervention. VAS (p-value=0,022), TSS (p-value=0,020) and BDC (p-value=0,003) was significant improved in 8 times administration group. VAS (p-value=0,045) dan BDC (p-value=0,014) was significant improved in 5 times administration group, where TSS improved but not significant. The 8 times administration group was better compared to the 5 times administration group in improvement of VAS (p-value=0,016). Based on this research, The addition of mecobalamin 8 times and over 5 times in the management of Diabetic Neuropathic Pain can be useful in reducing neuropathic pain.
Co-Authors Amran, Muhammad Yunus Andi Alfian Zainuddin Andi Kurnia Bintang, Andi Kurnia Ardhany, Andri Armalia, Armalia Baan, Junus Bahar, Ashari Basri, Muhammad I Blow, David Hamid, Firdaus Harun Muchsin, Achmad Irsyadat, Andi Muhammad Lotisna, Mimi Mansyur, Yunita Meryana*, A. Kurnia Bintang**, Muh. Akbar**, Susi Aulina**, Yudy Goysal**, Arifin Limoa*** Muhammad Akbar Setiawan, Denise Dewanto Tammasse, Jumraini Tirkal, Fahrian Umar, Batari Todja Walenna, Nirwana Fitriani Wuysang, Audry Devisanty