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All Journal Jurnal Penelitian Farmasi Indonesia JOPS (Journal Of Pharmacy and Science) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Farmasi Indonesia Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Septi Muharni
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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KADAR FENOLIK DAN FLAVONOID TOTAL SERTA AKTIVITAS ANTIOKSIDAN DARI EKSTRAK METANOL AKAR, DAUN DAN BUNGA SIMPUR AIR (Dillenia suffroticosa Griff. Ex Hook) Rahayu Utami Utami; Ginta Rio Maranti; Mustika Furi; Melzi Octaviani; Septi Muharni; Fina Aryani; Husnawati; Wira Noviana Suhery; Musyirna Rahmah Nst; Haiyul Fadhli; Emma Susanti; Emrizal
Jurnal Penelitian Farmasi Indonesia Vol. 10 No. 2 (2021): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v10i2.1418

Abstract

Simpur air is one of plant that has been using as traditional medicine for treating several diseases. Some studies on its chemical constituents and biological activities of this species have been published. However, chemical constituents and antioxidant activity of this plant which is Riau origin has not been reported before. This study aims to determine the total of phenolic and flavonoid content as well as its antioxidant activity of methanol extracts of roots, leaves and flowers of simpur air. Determination of total of phenolic and flavonoid content was performed by spectrophotometric method using Folin Ciocalteu and AlCl3 as reagents, respectively. Whereas, its antioxidant activity was evaluated using DPPH method. The results showed that methanol extracts of its roots afforded the highest total of phenolic and flavonoid content and also its antioxidant activity. The total of phenolic content of methanol extracts of its roots of 428.131 GAE/mg extract; its total of flavonoid content of 766.164 QE/mg extract; as for its antioxidant activity gave IC50 value of 3.852 µg/ml.
Pengetahuan Masyarakat tentang Suplemen Minuman Berenergi terhadap Risiko Penyakit Ginjal Kronik di Kelurahan Simpang Baru Kecamatan Tampan Pekanbaru Yolanda Fandra; septi muharni; ratna sari dewi
Jurnal Penelitian Farmasi Indonesia Vol. 8 No. 2 (2019)
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.071 KB) | DOI: 10.51887/jpfi.v8i2.575

Abstract

Energy drink supplement is a health product that contains one or more substances that are nutritional (vitamins, minerals and amino acids) or drugs. This study aims to look at public knowledge about the use of energy drink supplements for the risk of chronic kidney disease in Simpang Baru district, Tampan District, Pekanbaru city. This research is an observational / survey research which is descriptive in nature. Sampling was done by purposive sampling, samples obtained in this study were 100 respondents who used energy drink supplements at least once a week. The results showed that community knowledge in the Simpang Baru sub-district was included in the sufficient category (64.83%) with the division of categories of knowledge about the definition of a supplement with enough energy drinks (62%), the content of the supplement with enough energy drinks (65.66%), the purpose / reason consume adequate energy drink supplements (75%), effects / risks after taking adequate energy drink supplements (69.6%) and when consuming energy drink supplement people in the Simpang Baru sub-district community have less knowledge level (52.33%). From these results it can be concluded that public knowledge about the use of energy drink supplements in Simpang Baru village, Tampan sub-district, Pekanbaru city is included in the sufficient category (64.83%).
Analisa Kepuasan Pasien Rawat Jalan Terhadap Kualitas Pelayanan Di Instalasi Farmasi Rumah Sakit Islam Ibnu Sina Pekanbaru Fina Aryani; Husnawati Husnawati; Septi Muharni; utia Liasari; Richa Afrianti
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 12 No. 01 Juli 2015
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

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Abstract

ABSTRAK Penelitian tentang Analisa Kepuasan Pasien Rawat Jalan terhadap Kualitas Pelayanan di Instalasi Farmasi Rumah Sakit (IFRS) Islam Ibnu Sina Pekanbaru bertujuan untuk menganalisa tingkat kepuasan pasien rawat jalan di IFRS Islam Ibnu Sina Pekanbaru berdasarkan lima (5) dimensi kualitas pelayanan yakni tangible, responsiveness, reability, assurance, dan emphaty. Penelitian ini merupakan penelitian observasional dengan rancangan deskriptif. Pengambilan data dilakukan secara cross sectional menggunakan kuesioner berdasarkan nilai gap yaitu selisih antara nilai kinerja dan harapan. Sampel dalam penelitian ini sebanyak 120 orang responden yang memenuhi kriteria inklusi. Hasil penelitian didapatkan nilai gap terbesar pada aspek reliability yakni -0,85, assurance yakni -0,73, emphaty yakni -0,67, tangible yakni -0,59 dan aspek responsiveness -0,54. Hal ini menunjukkan bahwa pasien rawat jalan di IFRS Islam Ibnu Sina Pekanbaru belum merasa puas terhadap pelayanan yang diberikan. Kata kunci: analisa kepuasan, kualitas pelayanan, RS Islam Ibnu Sina Pekanbaru. ABSTRACT Research on Customers Satisfaction Analysis of Pharmaceutical Service Quality in IFRS Ibnu Sina Pekanbaru aims to analyze the level of customers satisfaction of outpatients in IFRS Islam Ibnu Sina Pekanbaru based on five (5) dimensions of service quality that is tangible, responsiveness, reability, assurance, and empathy. This research is observasional with descriptive design. Data collection was performed by cross sectional questionnaire based on the value gap is the difference between performance and expectations. The sample in this study were 120 respondents who met the inclusion criteria. The result showed the largest gap value on the reliability aspect of -0.85, -0.73 ie assurance, empathy ie, -0.67, -0.59 and the tangible aspects of responsiveness -0.54. This suggests that outpatient at Ibn Sina Pekanbaru Islamic IFRS has not been satisfied with the services provided. Key words: satisfaction analysis, service quality, RS Islam Ibnu Sina Pekanbaru
Analisis Efektivitas Biaya dan Terapi Antipsikotik Haloperidol-Klorpromazin dan Risperidon-Klozapin pada Pasien Skizofrenia Fina Aryani; Ditta Heriani; Nofriyanti Nofriyanti; Septi Muharni; Husnawati Husnawati
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 14 No. 01 Juli 2017
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

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Abstract

Penggunaan jangka panjang terapi antipsikotik merupakan beban biaya yang ditanggung pasien skizofrenia. Penelitian ini bertujuan untuk mengetahui perbedaan efektivitas biaya dan efektivitas terapi kombinasi oral haloperidol-klorpromazin (tipikal) dibanding terapi kombinasi oral risperidol-klozapin (atipikal) pada pasien skizofrenia di ruang Unit Perawatan Intensif Psikiatrik (UPIP) di salah satu rumah sakit jiwa yang ada di Provinsi Riau. Penelitian dilakukan secara prospektif menggunakan rekam medik periode Februari hingga Mei 2016, dengan teknik accidental sampling. Dimana didapatkan yaitu nilai ACER (obat) kelompok terapi haloperidol-klorpromazin Rp 402,90 sedangkan terapi risperidon-klozapin Rp 4.848,53 dan nilai ACER (total) kelompok terapi haloperidol-klorpromazin Rp 302.073,43 sedangkan terapi risperidon-klozapin Rp 339.476,85. Sehingga dapat disimpulkan bahwa terapi kombinasi haloperidol-klorpromazin lebih cost-effective.
PENGARUH MEDIA EDUKASI E-BOOKLET TERHADAP TINGKAT PERILAKU TENAGA TEKNIS KEFARMASIAN PADA PENGGALIAN INFORMASI SWAMEDIKASI COMMON COLD Septi Muharni; Fadila Toha; Fina Aryani; Husnawati
Jurnal Penelitian Farmasi Indonesia Vol. 11 No. 1 (2022): JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v11i1.1538

Abstract

Self-medication service is a high service practice carried out by pharmaceutical technical personnel, one of which is the common cold self-medication service. This demands a fairly high TTK role, one of which is in information research. The purpose of this study was to see the effect of providing educational media for TTK level e-booklets on common cold self-medication information. This research is quasi-experimental research: non-equivalent control group design using non-probability sampling method with purposive sampling technique. The sample in this study was 100 TTK who were registered with the Regional Board of the Indonesian Pharmacists Association of Riau Province and worked in pharmacies. The data were analyzed by marginal homogeneity test with significant results in the provision of educational media e-booklets on the level of TTK behavior in the treatment group during pre-test and post-test with p value = 0,011 (p <0.05). Based on the results of this study, it is said that presenting e-booklet educational media can increase TTK in Riau Province on the behavior of self-medication information on common cold.
Gambaran Kejadian Berpotensi Medication Errors Fase Prescribing Resep Pasien Rawat Jalan RSUD Arifin Achmad Riau Wardatul Jannah; Septi Muharni
JOPS (Journal Of Pharmacy and Science) Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3425

Abstract

Penelitian ini bertujuan untuk melihat persentase gambaran kejadian yang berpotensi medication errors fase prescribing pada resep pasien rawat jalan di Rumah Sakit Umum Daerah Arifin Achmad provinsi Riau. Penelitian ini merupakan penelitian observasional/survei yang bersifat deskriptif. Pengambilan sampel dilakukan dengan cara accidental sampling, sampel yang didapat dalam penelitian ini sebanyak 300 lembar resep pasien rawat jalan yang masuk pada saat penelitian dilakukan di RSUD Arifin Achmad. Hasil penelitian menunjukkan bahwa persentase tertinggi kejadian yang berpotensi medication errors fase prescribing resep pasien rawat jalan RSUD Arifin Achmad berdasarkan status pembayaran adalah persentase tertinggi pada resep pasien umum yaitu sebesar 27,78%. Berdasarkan asal dokter penulis resep persentase yang didapat adalah dokter umum yaitu sebesar 26,32% . Berdasarkan jumlah obat dalam resep persentase kejadian tertinggi adalah jumlah obat ≥5 yaitu sebesar 29,44%. Berdasarkan kelengkapan resep berat badan pasien 96,67%, tinggi badan pasien96,67% dan pada penelitian ini tidak ditemukan resep dokter yang tidak dapat dibaca, serta tidak terdapat singkatan nama obat yang tidak lazim. Hasil tersebut menunjukkan, bahwa medication errors fase prescribing pada resep pasien rawat jalan di RSUD Arifin Achmad masih tinggi.
ANALISIS RISIKO REAKSI OBAT YANG TIDAK DIKEHENDAKI PADA PASIEN HIPERTENSI GERIATRI DI RSUD ARIFIN ACHMAD PROVINSI RIAU Septi Muharni; Erniza Pratiwi; Yuwanda Iswari
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.224

Abstract

Adverse Drug Reaction (ADR) is every adverse event related to the use of a drug in humans. Geriatrics have a 7 times greater risk of developing ADR. Hypertension is the most common disease suffered by geriatric patients. The purpose of this study was to analyze the risk of ADR occurrence in geriatric hypertension patients and also to analyze the relationship of demographic data with the incidence of ADR. This study was carried out in an observational manner which was descriptive analytic with a cross sectional approach in 88 medical record samples of geriatric hypertension patients in inpatient installations using gerontoNET scores. Based on the ADR risk variable according to the gerontoNET score, there was 1 patient with ≥4 comorbid, 45 patients had heart failure, 5 patients had liver disorders, 19 patients received 6-7 drugs and 37 patients received ≥8 drugs, no patients with ADR history, and 28 patients developed kidney problems. From the results of this study, there are 37 patients who have a high risk of ADR events which are marked by gerontoNET score ≥4. Based on the correlation analysis of gender and age range on ADR risk obtained a weak relationship and no significant correlation (r = 0.116, p = 0.116; r = 0.017, p = 0.847), so that gender and age in geriatric hypertension patients are not related to the risk of ADR.
UJI INHIBITOR ENZIM TIROSINASE EKSTRAK DAN FRAKSI DAUN KEDABU (Sonneratia ovata Backer) SECARA IN-VITRO Furi, Mustika; Ainun Alfatma; Rahma Dona; Armon Fernando; Fina Aryani; Rahayu Utami; Septi Muharni; Husnawati; Wira Noviana Suhery; Melzi Octaviani
Jurnal Ilmiah Manuntung Vol 8 No 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.529

Abstract

Kedabu leaves (Sonneratia ovata Backer) are known contain secondary metabolites, one of which is phenolic, flavonoid and antioxidant activity. Phenolic, flavonoids and antioxidant are known to inhibit the tyrosinase enzyme. The tyrosinase enzyme is involved in the process of melanogenesis which produces melanin. Melanin can cause hyperpigmentation. To prevent hyperpigmentation, tyrosinase inhibitors are needed. This study aimed to test the tyrosinase enzyme inhibitor in ethanol extract, n-butanol fraction, ethyl acetate fraction, n-hexane fraction of kedabu leaf (Sonneratia ovatta Backer) using L-tyrosine as a substrate. The method used to get ethanol extract using ethanol maceration, while some fractions are obtained using the fractionation method. The test was carried out using L-tyrosine and kojic acid as a positive control with absorption measurements using microplate reader at a wavelength of 492 nm. The results showed that the best tyrosinase inhibitory activity was produced by the ethyl acetate fraction with an IC50 value of 18,82 g/mL, followed by the n-butanol fraction with an IC50 value of 24,42 g/mL, and the n-hexane fraction with an IC50 value. 28,77 g/mL, ethanol extract with an IC50 value of 99,09 with a strong category for all samples compared with kojic acid as a positive control with an IC50 value of 30,09 g/mL.
Effect of Flyers on Knowledge and Adherence to Medication of Hypertensive Patients Husnawati; Reni Zulfitri; Fina Aryani; Septi Muharni; Fitra Ramadhan
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 13 No. 1 (2021): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (323.025 KB) | DOI: 10.35617/jfionline.v13i1.111

Abstract

Knowledge and adherence to taking medication in patients with hypertension is very important because knowing and adhering in taking antihypertensive drugs can control the blood pressure of people with hypertension. The purpose of this study was to determine the effect of giving flyers on knowledge and adherence to taking medication for hypertensive patients. The method used in this research is a quasi-experimental method, with a non-randomized control group pretest and posttest design which was carried out on 96 respondents with purposive sampling technique. Collecting data for knowledge using the knowledge questionnaire, and adherence using the MMAS-8 scale. Data were analyzed using Wilcoxon test and Mann-Whitney test. The results of the study on hypertensive patients showed that giving flyers had a significant effect on knowledge with a p value = 0.000 and on patient adherence with a p value = 0.000.
Co-Authors Ainun Alfatma Armon Fernando Ditta Heriani Emma Susanti Emrizal Fadila Toha Fina Aryani, Fina Fitra Ramadhan Furi, Mustika Ginta Rio Maranti Haiyul Fadhli Husnawati Husnawati Husnawati Melzi Octaviani Musyirna Rahmah Nst Nofriyanti Nofriyanti Pratiwi, Erniza Rahayu Utami Rahayu Utami Utami Rahma Dona Ratna Sari Dewi Reni Zulfitri Richa Afrianti utia Liasari Wardatul Jannah Wira Noviana Suhery Yolanda Fandra Yuwanda Iswari