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Journal : Indonesian Applied Physics Letters

Optimization of Additional Composition Variations ZnO Nanoparticles on The Characteristics of Porous Hydroxypatite as Bone Filler Fardatul Azkiyah; Drs. Djony Izak Rudyardjo, M.Si.; Jan Ady
Indonesian Applied Physics Letters Vol. 2 No. 2 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v2i2.31699

Abstract

Research on the synthesis and characterization of porous hydroxyapatite with the addition of ZnO nanoparticles has been carried out through a combination of foam immersion and injection methods. This research was conducted to optimize the previous research by increasing the variation of ZnO composition and adding the injection method to the research process. The materials used in this research include hydroxyapatite nanoparticles, ZnO nanoparticles, Aquades, PVA and polyurethane foam. Manufacturing is done by immersing polyurethane foam into a slurry. Slurry is a mixture of PVA and hydroxyapatite solutions with variations in the addition of ZnO nanoparticles (8 wt%, 10 wt%, 12 wt%, and 14 wt%). Then inject the remaining slurry into the foam. After that the sample was dried and heated at a temperature of 650ºC to remove foam and PVA, then the sample was sintered at a temperature of 1200ºC for 3 hours. Based on SEM analysis, porosity test, and compressive strength test, the best results were shown by sample IV because it had a pore diameter of 142.9 – 371.4 m with a porosity of 69.983%, a compressive strength value of 1.8653 MPa and non-toxic. The best results have not met the standard for bone filler application. In further research, improvements need to be made by using other additives such as ZrO2, so that it can improve the mechanical properties of porous hydroxyapatite to meet standard bone filler applications.
CHARACTERIZATION SCAFFOLD 3D-PRINTING PLA WITH HYDROXYAPATITE-CHITOSAN-AgNPs COATING TO TREAT MANDIBULAR OSTEOMYELITIS Malini, Mirza Hema; Hanan, Annisa; Ady, Jan; Aminatun
Indonesian Applied Physics Letters Vol. 6 No. 2 (2025): Volume 6 No. 2 – December 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v6i2.84889

Abstract

Osteomyelitis The mandible can cause pathological fractures of the bones and interfere with the function of the mandible, so it is necessary to perform resection for the removal of the infected part. As a result of resection, it is necessary to carry out mandibular reconstruction using Scaffold. The study aims to discuss the effect of PLA surface modification with HA-Chitosan-AgNPs coating on morphological structure, porosity, compressive strength, hydrophilicity properties and antibacterial properties and determine the best sample variation from the characterization carried out. Scaffold made from PLA 3D-printing material using the Fused Deposition Modelling (FDM). The variation in composition (wt%) of hydroxyapatite-chitosan-AgNPs used as coatings was A (100:0:0), B (90:10:0), C (90:7:3), D (90:5:5), E (90:3:7), and F (90:0:10). The results obtained are Scaffold PLA with HA-chitosan-AgNPs coating has pores interconnected with rough surface walls. The porosity value varies between 40%-53%. HA-Kitosan-AgNPs as a surface modification are also able to increase compressive strength, antibacterial properties, and hydrophilicity Scaffold The PLA with the best sample variation is indicated by sample D (90:5:5). Based on these results, it shows that Scaffold PLA with HA-Kitosan-AgNPs coating is potentially used as a mandibular reconstruction.