Article Per Year (5 Year)
p-Index From 2021 - 2026
0.61
P-Index
This Author published in this journals
All Journal Chemistry Indonesian Journal of Chemical Research Jurnal Mandala Pharmacon Indonesia Jurnal Laboratorium Khatulistiwa
Abidin, Khoirul Rista
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Education Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Identifikasi Bakteri Escherichia Coli Pada Ulkus Diabetikum Studi di Klink Kanazawa Pontianak Menggunakan PCR gen 16S rRNA Nurhidayatulloh, Ariffialdi; Ramadhani, Natasya Intan; Abidin, Khoirul Rista; Suwandi, Edy; Salsabila, Aisha; Widodo, Kaltri; Andriani, Lulu; Hamidah, Najwa; Wulandari, Tri
Jurnal Laboratorium Khatulistiwa Vol 9, No 1 (2025): November 2025
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v9i1.1976

Abstract

Diabetes mellitus can lead to complications such as ulcers that are highly susceptible to bacterial infection. Escherichia coli is one of the pathogenic bacteria commonly found in diabetic foot ulcers. Accurate detection of E. coli species is essential to support appropriate infection management, and one of the reliable methods is Polymerase Chain Reaction (PCR) targeting the 16S rRNA gene. This study employed a descriptive design with an accidental sampling technique. Samples were obtained from swab specimens of diabetic foot ulcer patients. The procedures included culture on Eosin Methylene Blue (EMB) agar, Gram staining, bacterial DNA isolation, PCR amplification of the 16S rRNA gene, electrophoresis for visualization of PCR products, and sequencing for species confirmation. Based on the results of the study involving 30 diabetic foot ulcer patients at Kanazawa Clinic Pontianak, culture analysis showed that 4 isolates were positive for Escherichia coli. Gram staining further confirmed the presence of E. coli by demonstrating its characteristic morphology. The PCR results visualized through electrophoresis showed that 4 samples (13.3%) were positive for Escherichia coli based on the 16S rRNA gene, indicated by the presence of DNA bands at approximately 1500 bp. Sequencing analysis further confirmed the isolates as Escherichia coli with 99% similarity. 
Formulation and Characterization of Uncaria gambir (U. gambir) Extract Cream as an Anti-Psoriasis Candidate: In Silico and In Vitro Studies Abidin, Khoirul Rista; Nurhidayattulloh, Ariffialdi; Siregar, Febrina; Dermawan, Abdurrafi Maududi; Dwisari, Fath; Oktaviria, Oktaviria; Suchi, Suchi; Indriani, Melly; Putri, Firda Aulia; Prasetyaningsi, Hernyati; Shofia, Shofia
Indonesian Journal of Chemical Research Vol 13 No 3 (2026): Edition for January 2026
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2026.13-kho

Abstract

Background: Psoriasis is a chronic inflammatory skin disorder in which oxidative stress and COX-2–mediated pathways contribute to disease progression. Conventional topical therapies, particularly corticosteroids, are effective but associated with adverse effects and limited mechanistic targeting. Objective: This study investigated Uncaria gambir (U. gambir) extract as a natural anti-psoriasis candidate in a topical cream formulation through phytochemical, antioxidant, in silico, and physicochemical evaluations. Methods: The extract was screened for phenolic and flavonoid content and evaluated for DPPH radical scavenging activity (IC₅₀). Molecular docking of catechin against the COX-2 receptor was performed using quercetin as a reference. Cream formulations containing varying extract concentrations were assessed for pH, spreadability, and adhesiveness. Results: U. gambir extract exhibited very strong antioxidant activity (IC₅₀ = 6.84 ppm), falling within the range of highly active antioxidants, although less potent than vitamin C. Catechin showed stable COX-2 binding (−4.76 kcal/mol). The 4.5% cream formulation (F2) demonstrated optimal properties, with a skin-compatible pH (~7.5) and good spreadability (~5.5 cm). Conclusion: U. gambir extract shows promising potential as a natural topical agent targeting oxidative stress and inflammation in psoriasis, supporting further in vivo and clinical validation.
Antibacterial Activity of Bajakah Tampala (Spatholobus littoralis Hassk.) Methanol Extract in Roll-On Deodorant against Staphylococcus epidermidis Dwisari, Fath; Dermawan, Abdurraafi' Maududi; Rahma, Nur Atika; Tjoadri, Tessa Nathalia; Abidin, Khoirul Rista
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.865

Abstract

Body malodor results from the bacterial breakdown of apocrine gland secretions, with Staphylococcus epidermidis identified as a key contributor. Conventional deodorants often rely on synthetic compounds that may cause skin irritation or pose long-term health risks. This study aimed to formulate and assess an antibacterial roll-on deodorant containing methanolic extract of Spatholobus littoralis Hassk., a Kalimantan-native medicinal plant known for its antibacterial properties. The extract, prepared via maceration, was incorporated into a multiphase emulsion base comprising zinc ricinoleate, aluminum potassium sulfate, Carbopol 940, triethanolamine, Lexemul CS20, BHT, and phenoxyethanol. The formulations were evaluated for their physicochemical characteristics—pH, spreadability, adhesiveness, and homogeneity—as well as antibacterial activity against S. epidermidis using the disc diffusion assay. The extract-containing formulations (F1–F3) exhibited a beige color, herbal aroma, and uniform texture. The pH values (4.12–4.35) were within the dermally acceptable range. The spreadability varied from 4.59 to 4.81?cm, while the adhesiveness ranged from 0.34?s to 5.25?min, indicating favorable application and retention properties. Antibacterial testing showed inhibition zones of 10.40–12.37?mm, comparable to a commercial control (p?>?0.05). These findings suggest that S. littoralis extract is a potential natural, skin-compatible antibacterial agent for topical deodorant applications
Co-Authors Andriani, Lulu Dermawan, Abdurrafi Maududi Hamidah, Najwa Indriani, Melly Nurhidayattulloh, Ariffialdi Nurhidayatulloh, Ariffialdi Oktaviria, Oktaviria Prasetyaningsi, Hernyati Putri, Firda Aulia Rahma, Nur Atika Ramadhani, Natasya Intan Salsabila, Aisha Shofia, Shofia Siregar, Febrina Suchi, Suchi Suwandi, Edy Tjoadri, Tessa Nathalia Tri Wulandari Widodo, Kaltri