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Journal : Jurnal Katalisator

THE POTENTIAL OF VIRGIN COCONUT OIL (VCO) CAN INHIBIT THE DEVELOPMENT OF TUBERCULOSIS BACTERIA Suryani, Suryani; Lestari, Rinda; Rosita, Betti; Marisa, Marisa; Slamet, Nangsih Sulastri; Mardhatillah
JURNAL KATALISATOR Vol. 9 No. 1 (2024): Jurnal Katalisator Volume 9 No.1, April 2024
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v9i1.3025

Abstract

Virgin Coconut Oil (VCO) contains biochemical components, namely peptides called bacteriocins and can inhibit the growth of pathogenic bacteria. Tuberculosis (TB) is a disease caused by the pathogenic bacterium Mycobacterium tuberculosis. It has been widely studied that the potential of VCO to inhibit the growth of pathogenic bacteria such as inhibiting the growth of bacteria that cause Otitis Media Suppurative Khronis, such as Staphilocoous aureus, Staphilococcus edpidermidis, Klebsiella, Proteus, Pseudomanas aureginosa and others. But not many have studied the potential of Virgin Coconut oil to inhibit the growth of pathogenic bacteria that cause tuberculosis. Tuberculosis is very dangerous, because it attacks the lungs and other parts of the body, and is the leading cause of death worldwide. If VCO has the potential to inhibit the growth of pathogenic bacteria that cause tuberculosis, then the risk of death can be reduced. The purpose of this study is to study the potential of virgin coconut oil (VCO) to inhibit the development of tuberculosis bacteria. This research was conducted at the Chemistry Laboratory and Molecular Biology Laboratory of Perintis University Indonesia. The sample was the sputum of 5 TB patients from Pariaman Hospital, to be isolated for pathogenic bacteria. VCO is made by fermentation without the addition of a stater. It turns out that the bacteria isolated from sputum are Mycobacterium tuberculosis. VCO has the ability to inhibit the bacteria that cause tuberculosis, according to its concentration, the largest is at a concentration of 100%. Its antioxidant ability is among the weak ones. In general, VCO can be concluded that VCO has the potential to reduce the consequences of death.
ASPARTATE TRANSAMINASE IN CHRONIC HEPATITIS B PATIENTS AT AWALBROS BATAM HOSPITAL Suryani, Suryani; Dwika, Nubbeliano; Lestari, Rinda; Abrar, Mardhatillah
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3477

Abstract

Chronic hepatitis B (HBV) is a liver infection characterized by persistent replication of Hepatitis B virus (HBV). Viral load is a parameter often used to evaluate viral replication activity, while Alanine Transaminase (ALT) and Aspartate Transaminase (AST) often used as biomarkers to assess liver damage. Objective: This study aims to evaluate the correlation of HBV viral load to ALT and AST in patients with chronic hepatitis B at Awalbros Batam Hospital. Methods: This research used descriptive study by data collected from patients with chronic hepatitis B who had undergone testing assessments of HBV viral load, ALT and AST. Results: The results of this study is indicate a significant correlation of HBV viral load to ALT levels. Approximately 40% of patients showed elevated ALT levels in line with increasing HBV load, while AST increase was observed in only about 5% of patients. The stronger correlation was noted in ALT, likely due to its higher specificity to liver tissue compared to AST. Conclusion: Quantitative HBV load significantly influences ALT levels but has a less notable effect on AST levels. These findings support the role of ALT as a more reliable indicator of chronic HBV infection. The study also simplifies the clinical phases of infection into two main categories: active and inactive, based on presumed similarities in clinical patterns.