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Kandungan Senyawa Aktif Jahe Merah Menggunakan Metode Kromatografi Gas–Spektrometri Massa (GC-MS) Isnaini, Yuni Subhi; Bahra, Bahra; Simanjuntak, Melicha K
MAHESA : Malahayati Health Student Journal Vol 4, No 9 (2024): Volume 4 Nomor 9 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i9.15936

Abstract

ABSTRACT One of the physiological changes that occur in pregnancy and make pregnant women uncomfortable is nausea and vomiting or known as emesis gravidarum. Several pharmacological therapies are considered to treat nausea and vomiting, namely Vitamin B6 (Pyridoxine Hydrochloride), but the administration of vitamin B6 is less effective because many pregnant women are afraid to take medication, so non-pharmacological therapy is recommended, namely the administration of ginger candy. The purpose of this study is to examine the content of active compounds of red ginger from Sorong City, Manokwar Regency and Nabire Regency. This type of research is an experimental research with a cross sectional study research design. The samples in this study were Red Ginger from Sorong City, Manokwar Regency and Nabire Regency with a sampling technique using purposive sampling. This study analyzed the content of active compounds of red ginger. The results of the study showed that the content of ginger active compounds using the GC-MS method, the content of ginger active compounds from Sorong City had a higher content of gingerol active compounds with a retention area value of 1.44% compared to red ginger from Manokwari Regency and Nabire Regency. The conclusion is that the high content of gingerol compounds will be able to improve nausea and vomiting in pregnant women because Gingerol is considered the main cause of anti-emetic effects, while shogaol and galanolactone yes act on serotonin receptors, especially in the ileum. Keywords: Red Ginger, Active Compounds, GC-MS  ABSTRAK Salah satu perubahan fisiologis yang terjadi pada kehamilan dan membuat ketidaknyamanan pada ibu hamil yaitu mual dan muntah atau yang dikenal dengan emesis gravidarum. Beberapa terapi farmakologi dipertimbangkan untuk mengatasi mual muntah yaitu Vitamin B6 (Pyridoxine Hidroklorida) namun pemberian vitamin B6 kurang efektif karena banyak ibu hamil yang takut untuk minum obat sehingga direkomendasikan terapi non farmakologis yaitu pemberian permen jahe. Tujuan dari penelitian ini adalah untuk meneliti kandungan senyawa aktif jahe merah yang berasal Kota Sorong, Kabupaten manokwar dan Kabupaten Nabire. Jenis penelitian ini adalah penelitian eksperimen dengan rancangan penelitian cross sectional study. Sampel dalam penelitian ini Jahe Merah yang berasal dari Kota Sorong, Kabupaten manokwar dan Kabupaten Nabire dengan teknik pengambilan sampel menggunakan purposive sampling. Penelitian ini melakukan analisis kandungan senyawa aktif jahe merah menggunakan metode GC-MS yang dilakukan di Laboratorium Penelitian dan Pengujian Terpadu Universitas Gadjah Mada. Data yang diambil merupakan data primer. Hasil penelitian menunjukan bahwa kandungan senyawa aktif jahe menggunakan metode GC-MS, kandungan senyawa aktif jahe yang berasal dari Kota Sorong memiliki kandungan senyawa aktif gingerol lebih tinggi dengan nilai retention area adalah 1,44% dibandingkan jahe merah yang berasal dari Kabupaten Manokwari dan Kabupaten Nabire. Kesimpulan tingginya kandungan senyawa gingerol akan dapat mempenegaruhi mual muntah ibu hamil karena Gingerol dianggap sebagai penyebab utama efek anti muntah, sementara shogaol dan galanolactone ya bekerja pada reseptor serotonin, terutama di ileum. Kata kunci: Jahe Merah, Senyawa Aktif, GC-MS
Knowledge, attitude, practice and compliance to weekly iron supplementation among female public junior high school students in West Papua Isnaini, Yuni Subhi; Pihahey, Priscilla Jessica; Bahra, Bahra; Mintaningtyas, Sestu Iriami; Simanjuntak, Melicha Kristine; Fabanjo, Ivonne Junita
Public Health of Indonesia Vol. 10 No. 4 (2024): October - December
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v10i4.858

Abstract

Background:Research indicates that the total iron intake among female adolescents aged 10–12 years who experience anemia is approximately 5.4 mg/day, significantly lower than the recommended daily requirement of 20 mg/day according to the 2013 Indonesian Nutritional Guidelines (AKG). To address this issue, the Indonesian government has implemented the Pemberian Tablet Tambah Darah pada Remaja Putri(PPAGB) program, which involves administering one iron tablet weekly over 12 months. However, the program's effectiveness is hindered by insufficient awareness of anemia's consequences and resistance among adolescents to consume iron tablets regularly. Objective:This study aimed to examine the association between female students' knowledge, attitudes, and practices (KAP) and their adherence to consuming iron supplements at Public Junior High School 08 Prafi, Manokwari, Papua. Methods:A school-based cross-sectional study was conducted between August and November 2023 among adolescent girls. A total of 226 participants were enrolled, divided into two phases: 75 participants in the first phase and 151 in the second. Weekly supplementation was provided for 12 weeks using 60 mg iron tablets. Data were analyzed using univariate, bivariate, and multivariable logistic regression analyses with SPSS version 27 to determine significant associations between adherence to iron tablet consumption and related variables at a significance level of p < 0.05. Results:Multivariate logistic regression analysis identified that accurate knowledge (OR = 0.403; p < 0.05), positive attitudes (OR = 0.226; p < 0.001), and frequent best practices (OR = 0.449; p < 0.05) were significantly associated with higher adherence to iron tablet consumption among female students. Conclusion:The findings suggest that enhancing female students' knowledge, attitudes, and practices regarding anemia and iron supplementation is crucial for improving adherence to iron tablet programs. Effective interventions should include educational initiatives to raise awareness about anemia and its consequences, alongside strategies to promote positive health behaviors. Keywords:knowledge; attitude; practice; compliance; iron supplements; anemia; Papua; Indonesia
THE NUTRITIONAL STATUS OF TODDLERS IS A RISK FACTOR FOR MALARIA INCIDENCE AT KIMI HEALTH CENTER Popang, Christina Tien; Isnaini, Yuni Subhi; Mulyanti; Ester
International Journal of Health and Medicine Vol. 2 No. 1 (2025): January : International Journal of Health and Medicine
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhm.v2i1.217

Abstract

Malaria remains a global health issue, particularly in tropical and subtropical regions. In Indonesia, Papua Province specifically Nabire Regency reports a high incidence of malaria, although a decline has been observed since 2010. Infants and pregnant women are the most vulnerable groups. Nutritional status, influenced by dietary patterns, environment, and access to healthcare, plays a crucial role in susceptibility to malaria. Malnourished children are more prone to severe malaria infections due to their underdeveloped immune systems. This research focuses on Kimi Health Center in Nabire Regency and aims to explore the relationship between the nutritional status of children under five and malaria incidence in 2024. The goal of this study is to determine the relationship between the nutritional status of children under five and malaria incidence at Kimi Health Center, Teluk Umar District, Nabire Regency, in 2024. The research design employs an analytical descriptive approach with a cross-sectional method to analyze the relationship between nutritional status and malaria incidence. Data was collected at one point in time and analyzed using univariate and bivariate analysis with the Kendall tau-b test through SPSS software. The results show that nutritional status significantly influences susceptibility to malaria. Children with poor nutrition are at a higher risk of experiencing severe malaria due to immune system dysfunction. Malnutrition, such as Protein-Energy Malnutrition (PEM), worsens parasitemia and anemia. Nutrient deficiencies, including iron, vitamin A, and zinc, also weaken the immune system. Therefore, improving nutritional status is a crucial effort in malaria control within endemic areas.
Edukasi Akupresure Kombinasi Inhalasi Aromaterapi Lemon menggunakan Media Bantu Video untuk Menurunkan Mual Muntah bagi Ibu Hamil Trimester I Mintaningtyas, Sestu Iriami; Isnaini, Yuni Subhi
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 3 (2025): Volume 8 No 3 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i3.18137

Abstract

ABSTRAK Mual dan Muntah merupakan adaptasi fisiologis proses kehamilan yang disebabkan adanya perubahan sistem endokrin pada primigravida sekitar 60-80% dan multigravida 40-60%.(Rofi’ah et al., 2019) Peningkatan Hormon Chorionic Gonadotropin (HCG) dengan kadar tertinggi biasanya terjadi pada periode trimester I yaitu di usia kehamilan 12-16 minggu pertama. Masa kehamilan dapat terjadi masalah-masalah yang tidak diinginkan. (Handayani & Khairiyatul, 2019)Penatalaksanaan mual dan muntah pada kehamilan dilakukan tergantung berat ringannya gejala, pengobatan dilakukan dengan cara farmakologi maupun non farmakologi. Terapi farmakologi dengan pemberian antiemetik, antihistamin, anti kolinergik dan kortikosteroid, sedangkan terapi nonfarmakologi dilakukan dengan cara pengaturan diet, dukungan emosional, akupresure.(Rofi’ah et al., 2019) Tujuan untuk memberikan edukasi pengetahuan dan peningkatan keterampilan Akupresur dalam pengurangan frekuensi mual muntah pada ibu hamil trimester I. Metode yang digunakan dalam pengadian masyarakat ini adalah dengan pemberian materi, Diskusi, Pemutaran Video, Demonstrasi dan Praktek. Hasil kegiatan pengabdian kepada Masyarakat ini berjalan baik dan sesuai dengan tujuan. Edukasi Kesehatan dengan terapi komplementer yang diberikan dapat meningkatkan pengetahuan masyarakat sebelum dan sesudah diberikan dengan jumlah 12 responden ibu hamil dimana terjadi peningkatan skor pengetahuan sebelum diberikan media video dengan rata-rata nilai pengetahuan 7 sedangkan setelah diebrikan media video akupresure kombinasi inhalasi aromaterapi Lemon selama 7 hari terjadi peningkatan pengetahuan dengan nilai rata-rata 9 dari 10 dan mual muntah Ibu hamil trimester 1 berkurang. Kata Kunci: Akupresure, Kombinasi Inhalasi Aromaterapi Lemon, Media Video, Mual Muntah, Ibu Hamil  ABSTRACT Nausea and Vomiting are physiological adaptations of the pregnancy process caused by changes in the endocrine system in primigravida around 60-80% and multigravida 40-60%. (Rofi'ah et al., 2019) Increased Chorionic Gonadotropin Hormone (HCG) with the highest levels usually occurs in the first trimester, namely in the first 12-16 weeks of pregnancy. During pregnancy, unwanted problems can occur. Management of nausea and vomiting in pregnancy is carried out depending on the severity of the symptoms, treatment is carried out pharmacologically and non-pharmacologically. Pharmacological therapy with the administration of antiemetics, antihistamines, anticholinergics and corticosteroids, while non-pharmacological therapy is carried out by regulating diet, emotional support, acupressure. (Rofi'ah et al., 2019) The aim is to provide education, knowledge and improve Acupressure skills in reducing the frequency of nausea and vomiting in pregnant women in the first trimester. The methods used in this community service are by providing materials, Discussion, Video Screening, Demonstration and Practice. The results of this community service activity went well and in accordance with the objectives. Health Education with complementary therapy provided can increase community knowledge before and after being given with a total of 12 pregnant women respondents where there was an increase in knowledge scores before being given video media with an average knowledge score of 7 while after being given acupressure video media combined with Lemon aromatherapy inhalation for 7 days there was an increase in knowledge with an average value of 9 out of 10 and nausea and vomiting of pregnant women in the first trimester decreased.            Keywords: Acupressure, Combination of Lemon Aromatherapy Inhalation, Video Media, Nausea and Vomiting, Pregnant Women
Analysis of Nutritional Status in Toddlers and Malaria Incidence Popang, Christina Tien; Isnaini, Yuni Subhi; Mulyanti, Mulyanti; Ester, Ester
Indonesian Journal of Global Health Research Vol 6 No S6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6iS6.4826

Abstract

Poor nutritional status in toddlers and the high incidence of malaria are two major health issues that continue to be significant challenges in Indonesia, particularly in tropical regions such as Papua. Children's health is heavily influenced by these two factors, where malnutrition can weaken the immune system, making them more vulnerable to infectious diseases like malaria. Toddlers with poor nutritional status, such as stunting and undernutrition, are more likely to contract malaria, which in turn worsens their health condition and can lead to various long-term complications. This study aims to explore the relationship between the nutritional status of toddlers and malaria incidence at Kimi Health Center in Nabire Regency in 2024. Using a descriptive-analytic approach with a cross-sectional design, The population of this study consists of 804 toddlers at Kimi Health Center, with 118 samples selected using purposive sampling. The instrument used in this study is a standardized questionnaire, which includes questions about the respondents' characteristics and factual information regarding their condition, as well as the results of laboratory malaria tests with positive results, the study will analyze data using the Kendall Tau test. The findings highlight that poor nutritional status, including conditions like Protein-Energy Malnutrition (PEM), increases the risk and severity of malaria, impairing the immune response and exacerbating complications such as anemia. Conversely, excess nutrition, such as obesity, can also compromise immunity, increasing malaria risk. Nutrient deficiencies, such as in iron, vitamin A, and zinc, further affect immune function and vulnerability to malaria. Improving nutritional status is crucial for reducing the risk and impact of malaria, particularly in endemic areas like Nabire.