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Self Expanding Metallic Stent Placement as a Palliative Therapy for an Advanced Gastric Cancer Patient Rabbinu Rangga Pribadi; Gerie Amarendra; Marcellus Simadibrata; Ari Fahrial Syam
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 1, April 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (413.091 KB) | DOI: 10.24871/141201354-58

Abstract

Patients with gastric cancer which infiltrates distal esophagus often complain of dysphagia. Stenting is currently the therapy of choice for malignant dysphagia. Self expanding metallic stent (SEMS) placement has become the standard stenting therapy.We reported a case of 63 year old male patient with an advanced gastric adenocarcinoma which infiltrated distal esophagus who complained of dysphagia. The diagnosis was made based on esophago gastro duodenoscopy (EGD), histopathology study and contrast enhanced abdominal computed tomography (CT) scan. Patient underwent esophageal stenting successfully. This case report demonstrates SEMS placement as an effectivepalliation therapy in patient with an advanced gastric cancer which infiltrated distal esophagus.Keywords: gastric cancer, self expanding metallic stents, malignant dysphagia
Peran Tindakan Revaskularisasi terhadap Kesintasan Pasien Non ST Elevation Myocardial Infarction (NSTEMI) Amarendra, Gerie; Makmun, Lukman H.; Antono, Dono; Dewiasty, Esthika
Jurnal Penyakit Dalam Indonesia Vol. 1, No. 1
Publisher : UI Scholars Hub

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Abstract

Pendahuluan. Pengaruh revaskularisasi terhadap kesintasan pasien non ST elevation myocardial infarction (NSTEMI) masih belum jelas. Waktu revaskularisasi yang optimal pada pasien NSTEMI belum ditemukan. Penelitian ini bertujuan mengetahui pengaruh revaskularisasi terhadap kesintasan pasien NSTEMI, juga mengetahui pengaruh waktu revaskularisasi terhadap kesintasan pasien NSTEMI. Metode. Penelitian dengan disain kohort retrospektif diakukan terhadap 300 pasien non ST elevation myocardial infarction yang dirawat di RSUPNCM pada kurun waktu Desember 2006-Maret 2011. Data klinis, laboratorium, elektrokardiografi (EKG), ekokardiografi, dan angiografi koroner dikumpulkan. Pasien yang telah terhitung enam bulan setelah onset kemudian dihubungi melalui telepon untuk melihat status mortalitasnya. Perbedaan kesintasan revaskularisasi ditampilkan dalam kurva Kaplan Meier dan perbedaan kesintasan diantara dua kelompok diuji dengan Log-rank test dengan batas kemaknaan Hasil. Terdapat perbedaan kesintasan yang bermakna pada uji log rank (p Simpulan. Kesintasan enam bulan pasien NSTEMI yang menjalani terapi medikamentosa dan revaskularisasi lebih baik dibandingkan dengan terapi medikamentosa saja. Tidak terdapat perbedaan kesintasan enam bulan pasien NSTEMI berdasarkan waktu revaskularisasi.
Penyakit Ginjal Kronis : apakah pola makan berbasis nabati efektif? Kurniawan, Wawan; Hairunisa, Nany; Amarendra, Gerie
Jurnal Biomedika dan Kesehatan Vol 6 No 3 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.373-382

Abstract

Chronic kidney disease (CKD) is a global problem whose number of sufferers is increasing. Various methods have been widely used to prevent worsening of kidney function. In addition to controlling causative factors, diet planning also plays a role in improving kidney function. Confining protein utilization has long been a foundation of wholesome treatment for patients with CKD. In any case, the suggested sum of dietary protein admissions may change between consensus. A vegan who eats less that's exceptionally low in protein has appeared to diminish the chance of kidney failure in patients with progressed CKD. These findings indicate that protein sources can also influence the improvement of kidney function. Dietary medications play a good part in the management of CKD and avoiding or postponing kidney replacement therapy. The study proposes that a plant-dominant low-protein diet (PLADO) of 0.6–0.8 g/kg/day composed of >50% plant-based sources, managed by nutritionists prepared in non-dialysis CKD care, is promising and reliable with the exactness diet. Plant-based Very low-protein diets may inhibit decreased eGFR (estimated glomerular filtration rate) and the need for renal replacement therapy. This literature review aims to find evidence about the effectiveness of plant-based diets in treating cases of chronic kidney failure.
EFFECT OF INTRAMUSCULAR SECRETOME ON TREATMENT RESPONSE IN TYPE 2 DIABETES MELLITUS PATIENTS DIGAMBIRO, REZA ADITYA; AMARENDRA, GERIE; HASTUTY, DEWI; ILONA, FLORINDA; CHENDRASARI, JULIAN
Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Vol. 9 No. 1 (2026): Al-Iqra Medical Journal: Jurnal Berkala Ilmiah Kedokteran
Publisher : Journal Medical Universitas muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/fgmtjc48

Abstract

Introduction: This study meant to evaluate the efficacy of intramuscular mesenchymal stem cell derived secretome therapy to improve the glycemic control among diabetic patients with Type 2 Diabetes Mellitus (T2DM) on stable insulin or oral hypoglycemic agents (OHO). n=30 per group (Insulin + Secretome; OHO + Secretome). Methods: Pre–post controlled design; biweekly 2 mL intramuscular secretome for 12 weeks; primary outcomes HbA1c, FBG, 2hPP; standard tests per normality. Participants were divided into two groups: Insulin + Secretome and OHO + Secretome. All subjects received intramuscular injections of mesenchymal stem cell (MSC)-derived secretome (2 mL) every two weeks over a 12-week period (six injections total). Primary outcomes included changes in HbA1c, fasting blood glucose (FBG), and two-hour postprandial glucose (2hPPBG). Statistical analyses used paired t-tests or Wilcoxon tests for within-group comparisons and independent t-tests or Mann-Whitney U tests for between-group comparisons. Results: At baseline, both groups had comparable HbA1c and glucose profiles. After 12 weeks, significant reductions were observed in both treatment arms. HbA1c decreased by -1.10 ± 0.45 (Insulin) and -1.33 ± 0.36 (OHO); between-group ΔHbA1c (p < 0.05). Both groups also showed clinically relevant reductions in FBG and 2hPPBG levels. No major adverse effects were reported. Conclusion: Intramuscular MSC-secretome improved glycemic control across background therapies; the benefit was modestly greater with OHO. No majoradverse events were observed