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All Journal Keluwih: Jurnal Kesehatan dan Kedokteran The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia
Rabbinu Rangga Pribadi
Divisi Gastroenterologi, Pankreatobilier, Dan Gastrointestinal Endoskopi, Departemen Penyakit Dalam, Universitas Indonesia, Rumah Sakit Cipto Mangunkusumo, Jakarta, Indonesia
Agriculture, Biological Sciences & Forestry Health Professions Medicine & Pharmacology Nursing Public Health

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Diagnostic Findings of Sclerosing Mesenteritis and the Disease Correlations with Caecal Adenocarcinoma Rabbinu Rangga Pribadi; Murdani Abdullah; Rizka Puteri Iskandar; Velma Herwanto; Okto Dewantoro; I Wayan Murna Yonathan; Arman Adel Abdullah; Ening Krisnuhoni; Diah Rini Handjari
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 18, No 2 (2017): VOLUME 18, NUMBER 2, AUGUST 2017
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1245.218 KB) | DOI: 10.24871/1822017122-125

Abstract

Sclerosing mesenteritis (SM) is a rare disease with non-specific clinical manifestations and should be supported by radiological examination and confirmed by histopathological evaluation. Its relationship with cancer especially caecal adenocarcinoma is still unclear. This case report describes a young man who was diagnosed as having SM and poorly-differentiated caecal adenocarcinoma.
The Role of β-1.3/1.6-D-Glucan From Ganoderma lucidum Mycelium Extract in Ulcerative Colitis Marcellus Simadibrata; Aditya Rachman; Saskia Aziza Nursyirwan; Murdani Abdullah; Rabbinu Rangga Pribadi; Raja Mangatur Haloho; Anthony Eka Wijaya; Daniel Martin Simadibrata; Kaka Renaldi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 22, No 3 (2021): VOLUME 22, NUMBER 3, December 2021
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2578.736 KB) | DOI: 10.24871/2232021234-239

Abstract

Ulcerative colitis (UC) is an idiopathic inflammatory disease that affects the colon. Current pharmacological modalities to treat UC have various side effects; therefore, there is a demand to develop a new alternative medicine that can reduce side effects and increase drug efficacy. One candidate for alternative therapy is Polysaccharide Peptide which is extracted from Ganoderma lucidum mycelium. This Polysaccaharide has an active compound of Β-1,3/1,6-D-Glucan which has strong immunomodulatory and anti-inflammatory properties. Various studies have reported that Ganoderma lucidum polysaccharides can reduce inflammatory markers such as TNF-α, IFN-γ, and IL-17A, which is produced by colonic mucosal inflammation. In addition, β-1,3/1,6-D-Glucan has shown improvements in inflammatory parameters and intestinal immunological barrier function animal studies with artificial colitis and requires further research in humans before clinical applications. 
High-Protein Dietary Supplementation and Nutritional Status Improvement of Malnourished Patients in Hospital Care Marcellus Simadibrata; Fiastuti Witjaksono; Yohannessa Wulandari; Raja Mangatur Haloho; Rabbinu Rangga Pribadi; Murdani Abdullah; Aditya Rachman; Anthony Eka Wijaya; Batara Bisuk; Daniel Martin Simadibrata; Rizka Mutiara; Kaka Renaldi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 22, No 2 (2021): VOLUME 22, NUMBER 2, August 2021
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (736.079 KB) | DOI: 10.24871/2222021147-153

Abstract

Hospital malnutrition is common in Indonesia and other developing countries. In Asia, the prevalence of hospital malnutrition ranges between 27-39%. The causes of malnutrition in hospital care include insufficient food intake and increased catabolic processes due to underlying causes such as metabolic disease, infection, and malignancy. Several studies have demonstrated that malnutrition increases the morbidity and mortality of hospitalized patients, prolongs hospital stay, and delays recovery. Therefore, healthcare providers must recognize malnutrition early by conducting nutritional screening and assessment to prevent worsening of malnutrition and administer the optimal nutritional therapy to patients. Apart from giving a standard diet, high-protein food supplementation in liquid form remains a suitable alternative for patients, especially since it is easily digestible. A high protein diet is associated with a better mortality rate, better weight gain, and improved SGA score in patients.
Diagnosis of Acute Pancreatitis as a Compilation of Weil's Disease Rabbinu Rangga Pribadi; Christy Efiyanti; Rio Zakaria; Ari Fahrial Syam; Leonard Nainggolan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 13, NUMBER 3, Desember 2012
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.133 KB) | DOI: 10.24871/1332012181-184

Abstract

ABSTRACTWeil’s disease is a severe form of leptospirosis and caused by pathogenic strain of Leptospira. Weil’s disease affects many organs including pancreas. Acute pancreatitis in leptospirosis is quite rare. Diagnosis of acute pancreatitis in Weil’s disease is based on clinical features, biochemical, and radiologic examination. Sometimes histopathological examination is urged to confirm diagnosis. Management of acute pancreatitis in severe leptospirosis comprise of antibiotic for leptospirosis and supportive treatment for the acute pancreatitis. Early and appropriate treatment is mandated as it was studied to significantly decrease mortality riskWe reported a case of 42 year old man suffering Weil’s disease with multi organ complications. Patient complained diffuse abdominal pain. Although the abdominal ultrasonography did not show any abnormalities of the pancreas, the amylase and lipase showed striking results. He recovered uneventfully. This case report demonstrated acute pancreatitis as one of severe leptospirosis complications. Keywords: acute pancreatitis, Weil’s disease, severe leptospirosis
Bowel Cleansing Protocol in Colonoscopy: Does It Affect Blood Thiamine Level? Rabbinu Rangga Pribadi; Virly Nanda Muzellina; Marcellus Simadibrata
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 21, No 1 (2020): VOLUME 21, NUMBER 1, April 2020
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (123.647 KB) | DOI: 10.24871/211202022-25

Abstract

Background: The burden of vitamin B1 or thiamine deficiency in patients undergoing digestive surgery is quite enormous. In the field of gastroenterology, pre-colonoscopy preparation might affect thiamine level. However the burden is not well defined. This study was conducted to confirm whether there is significant decrease of blood thiamine level in post-colonoscopy compared to pre-colonoscopy group.Method: This cross-sectional study was carried out at gastrointestinal endoscopy center of Cipto Mangunkusumo National General Hospital, Jakarta from October 2018 to January 2019. The inclusion criteria were patients equal or more than 18-year-old who underwent colonoscopy. The exclusion criteria were malnutrition, history of post-gastrointestinal resection, definitive diagnosis of cancer, and chronic alcoholism.Results: The median value of blood thiamine level is 58 (20-78) for pre-colonoscopy group and 58 (25-79) for post colonoscopy group (p=0.31).Conclusion: There was no significant decrease of blood vitamin B1 level in post-colonoscopy compared to pre-colonoscopy group.
Self Expanding Metallic Stent Placement as a Palliative Therapy for an Advanced Gastric Cancer Patient Rabbinu Rangga Pribadi; Gerie Amarendra; Marcellus Simadibrata; Ari Fahrial Syam
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 1, April 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (413.091 KB) | DOI: 10.24871/141201354-58

Abstract

Patients with gastric cancer which infiltrates distal esophagus often complain of dysphagia. Stenting is currently the therapy of choice for malignant dysphagia. Self expanding metallic stent (SEMS) placement has become the standard stenting therapy.We reported a case of 63 year old male patient with an advanced gastric adenocarcinoma which infiltrated distal esophagus who complained of dysphagia. The diagnosis was made based on esophago gastro duodenoscopy (EGD), histopathology study and contrast enhanced abdominal computed tomography (CT) scan. Patient underwent esophageal stenting successfully. This case report demonstrates SEMS placement as an effectivepalliation therapy in patient with an advanced gastric cancer which infiltrated distal esophagus.Keywords: gastric cancer, self expanding metallic stents, malignant dysphagia
Efektivitas Efikasi Pemberian Antivirus Favipiravir pada Pasien Covid-19: Evidence Based Case Report Bastomy Eka Rezkita; Steven Irving; Rabbinu Rangga Pribadi; Marcellus Simadibrata
Keluwih: Jurnal Kesehatan dan Kedokteran Vol. 3 No. 2 (2022): Keluwih: Jurnal Kesehatan dan Kedokteran (June)
Publisher : Direktorat Penerbitan dan Publikasi Ilmiah, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/kesdok.V3i2.4786

Abstract

Abstract—COVID-19 pandemic is still a major global health problem. Currently, there are no specific treatment recommendations for Covid-19 patients. Currently, the number of studies discussing antiviral therapy is increasing, but the efficacy of giving antiviral to Covid-19 patients is still being debated. Favipiravir is an antiviral regimen that is widely used to treat moderate to severe Covid-19 patients. This report aims to identify how effective Favipiravir in Covid-19 patients. Literature searching was carried in four internet databases, including Pubmed, Scopus, EBSCO, and Cochrane Library based on inclusion and exclusion criteria. The validity, importance, and applicability of the article is the further examined. The article under review should have the same problems, interventions, and outcomes as the case. There were three selected meta-analysis studies that were equally valid and applicable to our patients. Study from Manabe show OR = 1.60, 95% CI = 1.03–2.40, p = 0.04. Study from Hassanipour show RR= 1.24, 95% CI: 1.09–1.41; p= 0.001. Study from Shrestha show RR = 1.25. 95% CI = 1.01-1.53, p = 0.01. Administration of Favipiravir as an antiviral in the treatment of Covid-19 patients can reduce viral load faster and provide better clinical improvement. Keywords: covid-19, effectiveness efficacy, favipiravir Abstrak—Pandemi COVID-19 masih menjadi permasalahan utama kesehatan dunia. Saat ini belum tersedia rekomendasi tatalaksana khusus pasien Covid-19. Jumlah studi yang membahas mengenai terapi antivirus semakin bertambah, namun efikasi pemberian terapi antivirus pada pasien Covid-19 masih menjadi perdebatan. Favipiravir merupakan regimen antivirus yang banyak digunakan sebagai tatalaksana pasien Covid-19 derajat sedang sampai berat. Laporan ini bertujuan untuk mengidentifikasi bagaimana efektivitas efikasi Favipiravir pada pasien Covid-19. Penelusuran literatur dilakukan pada empat database internet yaitu Pubmed, Scopus, EBSCO dan Cochrane library berdasarkan kriteria inklusi dan eksklusi. Validitas, Kepentingan dan Aplikabilitas artikel kemudian ditelaah lebih lanjut. Artikel yang ditelaah harus memiliki masalah, intervensi dan outcome yang sama dengan kasus. Terdapat tiga studi meta-analysis terpilih yang memiliki validitas yang sama dan dapat diterapkan pada pasien kami. Studi oleh Manabe didapatkan OR = 1,60, 95% CI = 1,03–2,40, p = 0,04. Studi oleh Hassanipour didapatkan RR= 1,24, 95% CI = 1,09–1,41, p= 0,001. Studi oleh Shrestha didapatkan RR = 1,25, 95% CI = 1,01-1,53, p = 0,01. Pemberian Favipiravir sebagai antivirus dalam pengobatan pasien Covid-19 dapat menurunkan viral load lebih cepat dan memberikan perbaikan klinis yang lebih baik. Kata kunci: covid-19, efektivitas efikasi, favipiravir
Preventing Malnutrition through Adequate Management of Gastrointestinal Dysmotility in Systemic Sclerosis Patients: A Literature Review Layadi, Eka Benhardi; Pribadi, Rabbinu Rangga; Teressa, Maria; Suharja, Felicia; Ichsan, Oemar
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 2 (2023): VOLUME 24, NUMBER 2, August, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2422023163-171

Abstract

Gastrointestinal dysmotility in systemic sclerosis occurs as the end result of extensive fibrosis of the gastrointestinal tract. The entire length of the tract from the esophagus to the anorectum could be affected, exerting various gastrointestinal symptoms. Clinical manifestations attributed to gastrointestinal dysmotility are associated with significant distress and an increased risk of nutritional impairment, reducing the the quality of life of systemic sclerosis patients. One of the most commonly overlooked gastrointestinal implications in systemic sclerosis is malnutrition. Once malnutrition ensues in the course of systemic sclerosis, the detrimental effects attributed to nutritional decline are difficult to reverse and pose an increased risk of mortality. Adequate management through timely diagnosis of gastrointestinal dysmotility and utilization of malnutrition screening tools for systemic sclerosis patients could prevent the progression to malnutrition and its negative impacts.
Pemberian Asupan Kalori Terestriksi vs. Asupan Kalori Standar yang Berlanjut pada Pasien Penyakit Kritis dengan Refeeding Syndrome: Laporan Kasus Berbasis Bukti Hapsari, Sukma; Pribadi, Rabbinu Rangga
Jurnal Penyakit Dalam Indonesia Vol. 12, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Refeeding syndrome is a different clinical symptom and metabolic disorder that occur during the reintroduction of nutrition in chronically malnourished patients. Calorie restriction can increase survival and reduce mortality rates. This evidence-based case report was developed to examine the influence of caloric restriction on mortality, morbidity, and duration of critical illness. A literature search was performed using PubMed, EBSCOHost, ScienceDirect, and Cochrane with the keywords: “critically ill,” “restricted caloric intake,” “standard caloric intake,” “mortality,” “morbidity,” and “duration”. Articles were appraised using the University of Oxford Centre for Evidence-Based Medicine (CEBM) tools. Two studies met the inclusion criteria. The first was a randomized controlled trial, which demonstrated that protocolized caloric restriction significantly improved 60-day survival in ICU patients with refeeding syndrome (91% vs. 78%, p = 0.002), although no significant difference was observed in days alive following ICU discharge (44.8 vs. 39.9 days, p = 0.19). The second was a meta-analysis, which suggested a trend toward reduced hospital mortality with hypocaloric feeding; however, risk ratios varied widely (0.23–5.54), and 30-day mortality differences were not statistically significant (RR: 0.79–3.00). In conclusion, while caloric restriction may not significantly impact overall mortality in chronically ill patients, it appears to improve 60- to 90-day survival in critically ill ICU patients with refeeding syndrome. One study noted a reduced risk of respiratory infection, though evidence on other complications remains inconclusive. A regimen of 20 kcal/hour for at least two days may be suitable for managing refeeding syndrome. Overall, caloric restriction may offer modest clinical benefits in this specific population.
Diagnostic Challenge in Distinguishing Crohn’s Disease from Lupus Enteritis in Systemic Lupus Erythematosus Patient: A Case Report Layadi, Eka Benhardi; Pribadi, Rabbinu Rangga; Ariane, Anna; Kartika, Emiliana; Handjari, Diah Rini; Idzni, Irsalina; Ichsan, Oemar; Putri, Megawati Ananda Hasbi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 1 (2023): VOLUME 24, NUMBER 1, April, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/241202389-97

Abstract

Diagnosing Crohn’s disease in systemic lupus erythematosus patients with gastrointestinal symptoms poses a great challenge, due to its rare occurrence and similarity of clinical characteristics between its differential diagnosis. We herein present a rare case of a patient diagnosed with systemic lupus erythematosus, complicated by renal involvement and conspicuous gastrointestinal manifestations. The non-specific gastrointestinal findings in this patient led to challenge in differentiating lupus enteritis from Crohn's disease, as they share many similar aspects in clinical manifestations, endoscopic findings, and histopathological findings. We herein provide the clinical judgement in reaching Crohn's disease in concurrence with systemic lupus erythematosus as the final working diagnosis through scrutinizing and comparing data from similar case studies in the past. 
Co-Authors Abdullah, Arman Adel Aditya Rachman Aditya Rachman Amanda Pitarini Utari Anna Ariane, Anna Anthony Eka Wijaya Anthony Eka Wijaya Ardhia Fefrine Indarta Ari Fahrial Syam Arman Adel Abdullah Bastomy Eka Rezkita Batara Bisuk Bhanu Kumar Christy Efiyanti Daniel Martin Simadibrata Daniel Martin Simadibrata Dewantoro, Okto Diah Rini Handjari Diah Rini Handjari Edi Mulyana Ening Krisnuhoni Enrik John Aguila Fiastuti Witjaksono Gerie Amarendra Hapsari, Sukma Hasan Maulahela Ichsan, Oemar Idzni, Irsalina Imelda Maria Loho Iskandar, Rizka Puteri Kaka Renaldi Kartika, Emiliana Layadi, Eka Benhardi Leonard Nainggolan Lutfie Lutfie Marcellus Simadibrata K Murdani Abdullah Nikko Darnindro Nikko Darnindro Okto Dewantoro Pitt Akbar Putri, Megawati Ananda Hasbi Raja Mangatur Haloho Raja Mangatur Haloho Rio Zakaria Rio Zakaria Rizka Mutiara Rizka Puteri Iskandar Ryan Herardi Saskia Aziza Nursyirwan Steven David Panggabean Steven Irving Suharja, Felicia Teressa, Maria Velma Herwanto Velma Herwanto Virly Nanda Muzelina Virly Nanda Muzellina Yohannessa Wulandari Yonathan, I Wayan Murna