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All Journal Biology, Medicine, & Natural Product Chemistry Biomedical Journal of Indonesia SRIWIJAYA JOURNAL OF MEDICINE Open Access Indonesian Journal of Medical Reviews Berkala Penelitian Hayati Jurnal Ilmu Kebidanan dan Kesehatan
Sutandar, Vivi Hendra
Universitas Sriwijaya
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health

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Journal : Biology, Medicine,

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GLUT4 as A Protein Target for T2DM Therapy with Natural Compounds Sutandar, Vivi Hendra; Saleh, Mgs. Irsan; Maritska, Ziske
Biology, Medicine, & Natural Product Chemistry Vol 12, No 1 (2023)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2023.121.289-293

Abstract

WHO reported 1.9 million death cases of diabetes patients in 2019. Diabetes is caused by damage in the pancreas which resulted in a lack of insulin or insulin resistance. Medication for T2DM mainly focuses on lowering blood glucose and treating affected organs. Current medications are still lacking, thus research is needed in finding novel medications to accommodate T2DM. This paper aims to present the current research on potential plant extract in increasing GLUT4 translocation in diabetes conditions. insulin resistance state affecting GLUT4 translocation which is important in affecting glucose uptake. Some research shows that plant extract proved to be potential in increasing the translocation of GLUT4 and helping lowering blood glucose levels.
Co-Authors Eka Amelia Elisa Nurnawati Evi Lusiana Hary Widjajanti Juninta, Tania Maulida Harwati Mgs. Irsan Saleh, Mgs. Irsan Muhammad Irsan Saleh Nina Tanzerina Nita Parisa NOVITASARI Saleh, M. Irsan Siti Alharzsa Ziske Maritska