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Co-incidence of COVID-19 and hepatocellular carcinoma during pregnancy: Double punches to disease severity and mortality? Abubakar, Azzaki; Yusuf, Fauzi; Firdausa, Sarah; Maghfirah, Desi; Gunawan , Andrie; Sari, Fitrah
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.264

Abstract

Hepatocellular carcinoma (HCC), a considerable leading cause of cancer-related deaths worldwide, is the most common primary liver cancer with poor prognosis and outcome. Many advances in prevention, screening, and new technologies in diagnostics and therapy have been achieved, but its incidence and mortality remain increasing. Co-infection of another viral disease in HCC patients with pregnancy might exacerbate the condition and double the mortality rate. The aim of this case report was to describe the co-infection of coronavirus disease 2019 (COVID-19) in an HCC patient during pregnancy. A 26-year-old woman with 16–17weeks of gestation was admitted to Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia with shortness of breath. The patient also reported that the abdomen expanded rapidly in the last three weeks, followed by severe pain and collateral vein appearance. Laboratory findings revealed anemia, leukocytosis, HBsAg reactive, hypoalbuminemia, hyperbilirubinemia, elevated liver enzymes, increased alpha-fetoprotein (AFP), and cancer antigen 125 (CA-125). Ultrasonography indicated gestation with a single fetus, an enlarged liver with a 9.9 x 9.4 cm nodule, and massive ascites. The patient was also RT-PCR-confirmed COVID-19. On day 8 of hospitalization, the patient suddenly reported severe abdominal pain. Ultrasonography revealed fetal distress immediately followed by fetal death. Adequate management of cancer pain, continuous evacuation of ascites, and other supportive care could not save the patient who died on the day 17 of hospitalization. In this case, we found no proof that the patient experienced cirrhosis prior to HCC. Pregnancy through hormonal alteration is thought to be the aggravating factor that accelerates the progression of pre-existing liver disease into carcinoma and infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worsened the outcome in this patient.
Strategi Inovatif Pemanfaatan Media Sosial untuk Mengoptimalkan Promosi Usaha Koko Donat di Kota Padang Sari, Fitrah; Iskandar, Silvia
Konsienti : Community Services Journal Vol. 2 No. 02 (2024): July
Publisher : PT. TAKAZA INNOVATIX LABS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61536/konsienti.v2i02.65

Abstract

Usaha Koko Donat merupakan salah satu UKM di Kota Padang yang memiliki potensi besar untuk berkembang melalui peningkatan strategi promosi dan pemasaran digital. Kegiatan Pengabdian kepada Masyarakat (PKM) ini bertujuan untuk membantu Koko Donat dalam memanfaatkan media sosial secara efektif sebagai sarana promosi yang dapat meningkatkan daya saing dan penetrasi pasar. Metode yang digunakan meliputi sosialisasi dan pelatihan langsung mengenai pembuatan profil bisnis yang menarik dan pengelolaan media sosial yang konsisten dan profesional. Hasil kegiatan ini menunjukkan bahwa melalui pendekatan yang sistematis dan dukungan strategi digital yang tepat, Koko Donat mampu meningkatkan keterlibatan pelanggan dan memperluas jangkauan pasar. Peningkatan pemahaman tentang pentingnya media sosial dalam bisnis juga berhasil memotivasi pemilik usaha untuk terus berinovasi dan mengembangkan usaha secara berkelanjutan. Dengan demikian, kegiatan ini memberikan kontribusi nyata dalam mendukung pertumbuhan usaha kecil menengah melalui pemanfaatan teknologi digital
THE IMPACT OF ADVERSE DRUG REACTION OCCURRENCE TO DRUG ADHERENCE LEVEL: A CROSS-SECTIONAL STUDY IN PATIENTS WITH TUBERCULOSIS Bakri, Tedy Kurniawan; Akmal, Raihanul; Vonna, Azizah; Sari, Fitrah
JURNAL FARMASI GALENIKA Vol 8 No 2 (2021): Jurnal Farmasi Galenika Vol 8 No 2
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v8i2.194

Abstract

Tuberculosis is well-known as an ancient disease that remains a global challenge until this era. The main goals of the treatment are to eradicate the colonization of acid-resistant basil and to prevent the occurrence of drug resistance. However, the accomplishment of this multi-drugs therapy is not always achieved due to several obstacles, one of is patient adherence to the treatment. Patient adherence is a considerable determinator that influenced by a number factors including the adverse drug reaction (ADR) which appeared to the patients. This study aimed to examine the correlation between adverse drug reaction and patients’ adherence to the anti-tuberculosis category 1 regimen during the intensive phase. This observational analytic study used cross sectional method and involved 35 subjects. Drug adherence level was measured using Medication Adherence Scale-8 (MMAS-8) questionnaire, the characteristics of ADR were collected using check list sheet of ADR, and the probability of ADR was analyzed using Naranjo Algorithm. The results showed that the majority of patients in this study were adherence to anti tuberculosis drugs (62,8%) and experienced ADR (74,3%). Bivariate analysis using chi-square statistical test showed there was significant correlation between adverse drug reaction and adherence to anti-tuberculosis drugs during the intensive phase treatment (P-value = 0,02288).
Hubungan Pengetahuan Dan Laporan Ibu Terkait Kejadian Ikutan Pasca Imunisasi Pada Bayi 0-24 Bulan Di Puskesmas Batoh Banda Aceh Bakri, Tedy Kurniawan; Fitria, Nanda; Desiyana, Lydia Septa; Vonna, Azizah; Sari, Fitrah
JURNAL FARMASI GALENIKA Vol 8 No 3 (2021): Jurnal Farmasi Galenika Vol 8 No 3
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v8i3.195

Abstract

Kejadian Ikutan Pasca Imunisasi (KIPI) merupakan semua kejadian medis yang tidak diinginkan terjadi dalam satu bulan setelah imunisasi dan belum tentu memiliki hubungan kausalitas dengan vaksin. Data laporan KIPI dicatat apabila ibu dari anak yang mengalami KIPI melapor ke pelayanan kesehatan. Salah satu hal yang mempengaruhi penanganan dan sikap ibu terkait KIPI pada anak adalah pengetahuan ibu. Tujuan penelitian ini adalah untuk mengetahui reaksi KIPI yang dialami oleh bayi 0-24 bulan, mengetahui proporsi tingkat pengetahuan ibu yang melaporkan KIPI atau tidak melaporkan KIPI serta hubungan antara pengetahuan ibu dan laporan ibu terkait KIPI pada anak. Penelitian ini merupakan jenis penelitian observasional analitik dengan menggunakan metode cross-sectional. Dilakukan wawancara terhadap 68 responden yang diperoleh berdasarkan teknik quota sampling. Data pengetahuan ibu diperoleh dengan menggunakan kuesioner pengetahuan ibu dan data terkait KIPI diperoleh dari formulir KIPI yang diterbitkan oleh Menteri Kesehatan RI. Hasil penelitian menunjukkan bahwa semua reaksi KIPI termasuk dalam reaksi KIPI ringan diantaranya demam (85,2%), bengkak (29,4%) dan kemerahan di lokasi penyuntikan (22%), diare (4,4%), muntah (4,4%), alergi (1,4%), sesak napas (1,4%), dan abses (1,4%). Ibu yang tidak melaporkan KIPI sebanyak 86,7% didominasi oleh ibu dengan tingkat pengetahuan cukup yaitu 47%, sedangkan ibu yang melaporkan KIPI sebanyak 13,2% didominasi oleh ibu dengan tingkat pengetahuan baik yaitu 5,8%. Berdasarkan hasil analisis menggunakan Fisher’s Exact sebagai uji alternatif menunjukkan bahwa tidak terdapat hubungan yang signifikan antara pengetahuan ibu dengan laporan ibu terkait KIPI pada anak (p-value = 0,231).
Pemanfaatan Media Sosial untuk Promosi Usaha Kuliner pada Warung Bakso Mas Arif di Kota Padang Sari, Fitrah; Iskandar, Silvia; Amelia, Deni; Maria Putri, Hesti
Konsienti : Community Services Journal Vol. 1 No. 01 (2023): July
Publisher : PT. TAKAZA INNOVATIX LABS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61536/konsienti.v1i01.12

Abstract

Community Service is a form of the Tridarma of Higher Education. This Community Service is purpose to carry out socialization and educational activities in Culinary Business SMEs at Warung Bakso Mas Arif in Padang City. The general objective of this community service activity is to provide additional knowledge and understanding of the efforts that can be made by business owner to increase sales through increased promotion or marketing by utilizing social media. In this case business owners can make efforts to increase sales through the use of social media which is one of the business solutions in increasing their business marketing. By utilizing social media platform wisely, these SMEs can expand their market reach, build relationships with costumers and promote their products or services but in an easier and free way.
Strategi Digital untuk Meningkatkan Penjualan UMKM di Kelurahan Jati Timur Amelia, Deni; Sari, Fitrah; Bella, Shinta
Konsienti : Community Services Journal Vol. 2 No. 01 (2024): January
Publisher : PT. TAKAZA INNOVATIX LABS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61536/konsienti.v2i01.43

Abstract

Kegiatan PKM bertujuan untuk meningkatkan pemahaman dan penerapan media sosial dalam promosi produk bagi pelaku Usaha Mikro, Kecil, dan Menengah (UMKM) di Kelurahan Jati Baru, Padang Timur. Melalui sosialisasi dan praktek langsung, para peserta mendapatkan pengetahuan yang lebih mendalam tentang manfaat dan teknik pemasaran digital. Hasil dari kegiatan ini menunjukkan peningkatan signifikan dalam wawasan, pengetahuan, dan keterampilan peserta terkait pemanfaatan media sosial untuk promosi produk UMKM. Selain itu, saran untuk kegiatan lanjutan seperti pelatihan fotografi, kewirausahaan, dan penulisan media cetak diusulkan untuk memperluas kapasitas dan potensi peserta. Kolaborasi antara dosen, pelaku UMKM, dan masyarakat dalam kegiatan ini memberikan kontribusi positif terhadap pengembangan UMKM di wilayah tersebut.
Analisis Pengaruh Tingkat Pendidikan Dan Kompensasi Terhadap Produktivitas Kerja Pegawai Kantor Dinas Pasar Kota Padang Gustina, Leni; Rahmi Aswin, Ullya; Sari, Fitrah
Jurnal Ekonomika Dan Bisnis (JEBS) Vol. 2 No. 2 (2022): Jurnal Ekonomika dan Bisnis (JEBS)
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jebs.v2i3.230

Abstract

This study aims to examine and analyze the effect of education level and compensation on work productivity of employees of the Padang City Market Service Office. The independent variables used are education level (X1) and compensation (X2). The dependent variable is employee work productivity (Y). The type of research methodology used is the causative method. The data used are primary and secondary data. Primary data was obtained by interviewing a sample of 97 Padang City Market Service employees. The analysis tool used is Multiple Linear Regression with the SPSS version 19.0 program. The results of the study show that the first hypothesis (H1) can be accepted. It can be seen that the tcount value for this variable is 3.137. Meanwhile the value in the 5% distribution table is 2.376. Then tcount (3.137) > ttable (2.376). This means that the education level variable (X1) has a positive influence. This is also reinforced by the significance value (0.004 <0.050) meaning that the education level variable (X1) has a positive and significant effect on the work productivity of Padang City Market Service employees. Whereas the second hypothesis (H2) is also accepted, seen in the tcount value for this variable of 5.020. Meanwhile the value in the 5% distribution table is 2.376. Then tcount (5.020) > ttable (2.376). This means that the compensation variable (X2) has a positive influence. This is also reinforced by the significance value (0.000 <0.050) meaning that the compensation variable (X2) has a positive and significant effect on the work productivity of Padang City Market Service employees. For the third hypothesis (H3) it is also accepted that Fcount is 15.535, while the results of Ftable in the distribution table with an error rate of 5% are 3.44. This means Fcount > Ftable (15.535 > 3.44). These calculations show that the variable level of education (X1) and compensation (X2) together have a positive and significant influence on employee productivity variables (Y).