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Single nucleotide polymorphism analysis of the peroxisome proliferator-activated receptor gamma gene in type 2 diabetes mellitus patients at Ministry of Defense Hospital, RSPPN Soedirman Jakarta Sakdiyyah, Luluk; Hadi, Apip; Maladan, Yustinus; Tuba, Syahrul
International Journal of Applied Mathematics, Sciences, and Technology for National Defense Vol 3, No 2 (2025): International Journal of Applied Mathematics, Sciences, and Technology for Natio
Publisher : FoundAE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58524/app.sci.def.v3i2.830

Abstract

Type 2 diabetes mellitus is a metabolic disorder influenced by genetic and environmental factors. The Peroxisome Proliferator-Activated Receptor Gamma gene is known to play a role in T2DM pathogenesis, but its polymorphism profile in Indonesian patients remains poorly characterized. This study aimed to analyze single nucleotide polymorphisms in the PPAR-γ gene of T2DM patients at Rumah Sakit Pusat Pertahanan Negara (RSPPN) Soedirman Jakarta using adaptive sampling with nanopore sequencing. Eighteen DNA samples that passed quality control were analyzed using UGENE v52.1. A total of 26 SNPs were identified in 8 subjects, including C161T, which has a reported protective effect in T2DM. The clinical significance of the remaining SNPs remains unclear. This study provides initial insights into genetic variation in T2DM, which may contribute to personalized medical strategies for military personnel and support the development of a more resilient national defense health system by improving disease prevention and management in high-risk populations.
Factors Influencing and Information Technology Interventions for Nurse Compliance on Patient Safety: A Systematic Review Setiawati, Deni; Setyowati, Setyowati; Hariyati, Rr. Tutik Sri; Mediati, Ati Surya; Hidayanto, Achmad Nizar; Tuba, Syahrul
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 4 (2024): February
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i4.3473

Abstract

Patient safety is a critical global issue, prevalent in many countries. This research aims to review publications and literature regarding the factors and interventions that aid in nurse compliance with patient safety measures. Due to limited published studies on this topic, we conducted a systematic review to identify these factors and interventions based on existing literature. We searched  databases including Scopus, Science Direct, PubMed, and ClinicalKey Nursing, using specific keywords, filtering 1918 articles down to 22 articles for analysis. The study reveals that nurse implementation of patient safety is influenced by organizational culture and leadership, resource accessibility, physical facilities, communication and collaboration, workload and job satisfaction, nurses' knowledge and skills, demographic factors, and their attitudes and perceptions. Interventions for enhancing nurse compliance in patient safety include providing training and education through technological approaches, and health service delivery via information technology systems. This review offers insights into resolving nurse compliance issues in patient safety, highlighting the importance of not only individual nurses but also hospital management and the healthcare delivery system. Effective management strategies to increase  nurse compliance in patient safety should involve hospital authorities and improvements in the nursing service system.
Metaverse for Health: Future Opportunities, Challenges, and Recommendations Tuba, Syahrul; Arief , Ilham; Sudasman, Fuad Hilmi; Bakhar, Muhamad; Ernawati, Kholis; Thomason, Jane
Jurnal Ners Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i1.19720

Abstract

Metaverse is a concept that refers to a virtual world that is globally integrated and can be accessed by many people from various places. This research aims to further discuss the metaverse for health and its challenges. The method used by researchers in this study is the literature research method. The benefits of metaverse technology for health include health education, health therapy, health remote monitoring, health research, telemedicine, health rehabilitation, and health specialist consultations. The challenges that must be faced by the metaverse in health include relatively new technology, high-quality standards, accessibility, regulation, health professionals (doctors, nurses, etc.) must be trained, interoperability, adaptation, a large investment of funds, clinical studies, and so on.
Hubungan Pengetahuan, Sikap, dan Pengalaman Keluarga Sakit Demam Berdarah Dengue dengan Pencegahannya Tuba, Syahrul; Mariani, Ria; Faizah, Ana; Sutriyawan, Agung; Ramadhan, Afif
The Indonesian Journal of Infectious Diseases Vol. 9 No. 2 (2023): The Indonesian Journal of Infectious Disease
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v9i2.168

Abstract

Latar Belakang: Jumlah kasus demam berdarah dengue di kota Bandung masih tinggi yaitu 2.790 kasus. Upaya untuk mengatasi jumlah kasus dan kematian yang terus meningkat, salah satu program pencegahan adalah memutus rantai penularan dengan pemberantasan sarang nyamuk. Tujuan: Penelitian ini untuk menganalisis hubungan pengalaman sakit demam berdarah dengue, pengetahuan dan sikap dengan praktik pemberantasan sarang nyamuk. Metode: Penelitian ini menggunakan desain cross sectional. Populasi dalam penelitian ini adalah seluruh keluarga di wilayah kerja Puskesmas Ujung Berung Indah. Sampel diambil secara simple random sampling sebanyak 116 ibu rumah tangga. Subjek penelitian ini adalah ibu rumah tangga. Instrumen yang digunakan dalam penelitian ini adalah kuesioner. Uji statistik yang digunakan adalah chi square. Hasil: Hasil penelitian didapatkan sebagian besar responden ada pengalaman sakit demam berdarah dengue (61,2%) dan memiliki sikap kurang mendukung terhadap pencegahan demam berdarah (73,3%). Lebih dari setengah responden melakukan praktik pemberantasan sarang nyamuk kurang baik (56%) dan berpengetahuan rendah (54,3%). Variabel yang berhubungan dengan praktik pemberantasan sarang nyamuk adalah pengalaman sakit demam berdarah dengue (p=0,003, POR=3,4), pengetahuan (p=0,007, POR=3,0), dan sikap (p=0,013, POR=3,1). Kesimpulan: Pencegahan demam berdarah dengue dapat dilakukan dengan meningkatkan pengetahuan dan sikap ibu rumah tangga, serta pengalaman sakit dapat mengubah perilaku ibu rumah tangga untuk melakukan pemberantasan sarang nyamuk.