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Perbandingan Variasi Lamanya Waktu Penyangraian Terhadap Kadar Kafein Pada Biji Kopi Robusta Secara Spektrofotometri UV-Vis Panji Ratih Suci; Vania Angel; Nur Aini
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 4 No. 1 (2024): Maret : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v4i1.2975

Robutsta coffee is one of the most popular beverages in the world is consumed by many people. The main compound in coffee beans is caffeine. This compound affects the central nervous system, muscles, and kidneys. Caffeine cluster has kromoform, so it can be read using its absorbance of UV-Vis spectrophotometry. This research aims to know the level of caffeine in coffee beans with variation of roasting time duration. The determination of the levels of caffeine by using quantitative analysis, by way of determination of wavelength maximum, operating time, raw curve, and the determination of the levels of caffeine on the sample with variations of roasting time. Determination of the wavelength, the parent solution taken 10 ml, 50 ml measuring flask put in added HCI 0,1 N up to the mark with a boundary. The next assigment that is the determination of the levels of caffeine in samples. Each sample taken as many 3 ml filtrate into a 50 ml measuring flask, then added HCI 0,1 N up to the mark with a boundary. The result obtained in this research is the maximum wavelength obtained 274,0 nm. The sample content of raw robusta coffee beans is an average of 1,77% and robusta coffee bean content with variations of roasted time of 10 minutes is an average of 1,62 %, roasted time of 15 minutes is an average of 1,31 %, and roaster time of 21 minutes is an average of 1,10 %. The duration of the roasting test indicates that is a significant difference in caffeine content.

Perbandingan Variasi Lamanya Waktu Penyangraian Terhadap Kadar Kafein Pada Biji Kopi Robusta Secara Spektrofotometri UV-Vis Panji Ratih Suci; Vania Angel; Nur Aini
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 4 No. 1 (2024): Maret : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v4i1.2975

Robutsta coffee is one of the most popular beverages in the world is consumed by many people. The main compound in coffee beans is caffeine. This compound affects the central nervous system, muscles, and kidneys. Caffeine cluster has kromoform, so it can be read using its absorbance of UV-Vis spectrophotometry. This research aims to know the level of caffeine in coffee beans with variation of roasting time duration. The determination of the levels of caffeine by using quantitative analysis, by way of determination of wavelength maximum, operating time, raw curve, and the determination of the levels of caffeine on the sample with variations of roasting time. Determination of the wavelength, the parent solution taken 10 ml, 50 ml measuring flask put in added HCI 0,1 N up to the mark with a boundary. The next assigment that is the determination of the levels of caffeine in samples. Each sample taken as many 3 ml filtrate into a 50 ml measuring flask, then added HCI 0,1 N up to the mark with a boundary. The result obtained in this research is the maximum wavelength obtained 274,0 nm. The sample content of raw robusta coffee beans is an average of 1,77% and robusta coffee bean content with variations of roasted time of 10 minutes is an average of 1,62 %, roasted time of 15 minutes is an average of 1,31 %, and roaster time of 21 minutes is an average of 1,10 %. The duration of the roasting test indicates that is a significant difference in caffeine content.

Aktivitas Sedatif Kombinas Ekstrak Putri malu (Mimosa pudica) dan Kayu secang (Caesalpinia sappan L) pada Mencit (Mus musculus) Panji Ratih Suci; Revi Syahrin A
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 2 No. 2 (2024): April : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v2i2.3572

Insomnia is a common sleep disorder. Insomnia can be managed with the use of sedative-hypnotic drugs, however, long-term use and specific dosages can lead to dangerous side effects. Therefore, alternative treatments utilizing natural substances such as Mimosa pudica and Caesalpinia sappan are needed. This study utilized 25 randomly divided mice into 5 groups. Diazepam was used as the positive control (+), aquadest and agar as the negative control (-), the group Extract MP (Mimosa pudica), Extract CS (Caesalpinia sappan), and the combination of Extract MP+CS (24mg/kgBW). Administration of the suspension was done orally via gastric lavage. The conclusion drawn from this study is that ethanol extracts of Mimosa pudica (MP), Caesalpinia sappan (CS), and their combination (MP+CS) at a dosage of 24 mg/kgBW exhibit sedative effects. Their effects and combination are comparable to standard synthetic drugs.

Analisis Kadar Logam Berat Timbal (PB) pada Makanan Kaleng Daging Giling Berbagai Merk Panji Ratih Suci; Muh. Latif 'Alim; Sulfika Oriza Nova Sativa
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.276

Along with increasingly rapid technological developments in our country, the number of existing industries is increasing. Apart from producing useful products, this industry also produces waste. The waste produced contains a lot of heavy metals, one of which is the heavy metal lead. If the lead metal in the waste receives little treatment, this can cause pollution in the environment, even though this waste is present in small quantities, the lead condition is unstable and if it accumulates in the body, it can ultimately trigger cancer cells (carcinogenic) which can be dangerous for health. . In this research, adsorption of PB2+ ions was carried out on canned ground meat, where heavy metal contamination occurred in the ground meat. This research aims to determine the effectiveness of the absorption of heavy metals (Pb) contained in ground beef and their characteristics. The uptake of PB2+ ions in ground beef, measuring the concentration of PB2+ ions before and after receiving treatment, was carried out using an instrument, namely AAS, at a wavelength of 217nm. The research results showed that the effectiveness of ground beef in absorbing PB2+ ions in canned food was as high as brand a: 0.023; brand b: 0.009; brand c: 0.006

Efektivitas Sabun Cuci Tangan Ekstrak Daun Afrika ( Vernonia amygdalina Del.) Terhadap Bakteri Escherichia coli Panji Ratih Suci; Cikra Ikhda Nur H.S; Anita Candra Ningtyas; Annisa Lailatul Maghfiroh
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.364

African leaf plants (Vernonia amygdalina Del.) is one of tradisional medicine and has pharmacological contain secondary metabolite such as Flavonoids, Saponin, Tanin and Alkaloid. This study aimed to determine the antibacterial activity of African leaf extract (Vernonia amygdalina Del.) in handsoap formulation on the growth of Escherichia coli. African left extract was obtained from maceration process with ethanol and phytochrmical screening was carried out.This study uses concentration of 0,5%, 1% and 2%. Antibacterial activity testing using scratch and disc diffusion methods. Tis study also evaluated the pyshical quality of the preparation which included organoleptic observation, homogeneity test, high foam test and antibacterial activity test. Antibacterial activity testing using scratch and disc disfusion methods. African pyctochemical screening was carried out. The result showed that the percentage of African leaf extract yield was 24,958%. The pH test gets a pH of 10-11 and 5-6 cm foam height test. The highest concentration of positive control of preparation containing alcohol (Dettol) with an average number og 4,72 mm ± 1,45 mm. Liquid soap preparation 1% with a diameter of inhibition of 3,93 mm ± 1,97 mm. The result of this study inhibit the growth of Eshcherichia coli bacteria.

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