Article Per Year (5 Year)
p-Index From 2021 - 2026
2.064
P-Index
This Author published in this journals
All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN e-GIGI JURNAL GIZI INDONESIA Jurnal Kedokteran Diponegoro The Journal of Experimental Life Sciences (JELS) Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Kesehatan Masyarakat Jaringan Laboratorium Medis Medica Arteriana (Med-Art) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Desy Armalina
Department Of Anatomy And Histology, Faculty Of Medicine, Universitas Diponegoro, Semarang, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

Published : 13 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 13 Documents
Search

 1   2 
Mikroskopis Preparat Mus Musculus Jaringan Ginjal yang Dideparafinisasi dengan Minyak Zaitun pada Pengecatan Hematoxylin Eosin (HE) Pratiwi, Ela Nur; Armalina, Desy
Jaringan Laboratorium Medis Vol. 3 No. 1 (2021): May 2021
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v3i1.8005

Abstract

Deparaffinization is a stage before the staining process to remove/dissolve paraffin so that the absorption of color in tissue preparations is maximized. Deparaffinization is usually carried out using xylol and toluol. Xylol has toxic effects including acute neurotoxicity, heart and kidney damage, hepatotoxicity, fatal blood dyscrasias, skin erythema, dry skin, peeling skin, and also has a carcinogenic effect. The toxicity effect of olive oil is lower than that of xylol. Oils that have non-polar properties can remove the remaining paraffin contained in the tissue. The purpose of this study was to determine the microscopic appearance of the kidney tissue preparations of mice deparaffinized with olive oil on hematoxylin eosin (HE) staining. The type of research used is experimental research which is analyzed with a descriptive approach. The results of the assessment of preparations deparaffinized with xylol in 80 visual fields obtained 100% good preparations and preparations deparaffinized with olive oil in 80 visual fields obtained 0% poor preparations, 11.3% poor preparations, and 88.7% good preparation. So it can be said that better results are found in the microscopic picture of the kidney preparations of mice (Mus musculus) deparaffinized with xylol.
FAKTOR RISIKO KANKER PAYUDARA PADA WANITA USIA PRODUKTIF DI RSD K.R.M.T WONGSONEGORO SEMARANG dewi, nasywa laksita; Surati, Surati; Armalina, Desy
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 10 No. 1 (2025): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v10i1.3521

Abstract

Kanker payudara merupakan jenis kanker penyebab utama kematian pada wanita. Berdasarkan data Global Burner Of Cancer (GLOBOCAN) pada tahun 2020, terdapat 68.858 kasus baru di Indonesia dan lebih dari 22.000 kematian. Penyakit ini berkembang secara perlahan dengan berbagai faktor risiko seperti usia, usia menarche, usia melahirkan, penggunaan alat kontrasepsi hormonal, riwayat keluarga, kebiasaan merokok, gaya hidup dan obesitas. Penelitian ini bertujuan untuk mengetahui adanya faktor risiko kanker payudara pada wanita usia produktif (15–59 tahun) di RSD K.R.M.T Wongsonegoro Semarang. Pendekatan secara kualitatif dengan metode penelitian deskriptif berdasarkan pengumpulan data sekunder berupa catatan rekam medis di RSD K.R.M.T Wongsonegoro Semarang. Sampel yang diambil sebanyak 100 pasien kanker payudara. Hasil penelitian menunjukkan bahwa sebagian besar pasien berada dalam kelompok usia produktif (87%), mengalami menarche dini (< 12 tahun) sebesar (3%), riwayat melahirkan pada usia produktif (89%), menggunakan kontrasepsi hormonal (56%), seluruh pasien tidak memiliki kebiasaan merokok (100%), usia menarche dengan penggunaan alat kontrasepsi hormonal (67%) dan rentang usia produktif saat pertama terdiagnosa dengan penggunaan alat kontrasepsi hormonal (52%). Kesimpulan dari hasil penelitian ini faktor risiko usia saat terdiagnosis, usia melahirkan, serta penggunaan alat kontrasepsi hormonal menunjukkan adanya faktor risiko. Namun, tidak ditemukan adanya faktor risiko pada kebiasaan merokok dan usia menarche.
Mobile Phone Electromagnetic Waves and Pregnancy Outcomes: An Experimental Study in Mice Armalina, Desy; Susilaningsih , Neni; Sutanto, Heri; Sunarno, Sunarno
The Journal of Experimental Life Science Vol. 15 No. 3 (2025)
Publisher : Graduate School, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jels.2025.015.03.06

Abstract

This study investigated the impact of mobile phone–derived electromagnetic wave (EMW) exposure on the uterus and progeny of pregnant Balb/c mice. Fourteen pregnant mice were randomly assigned to two groups (n=7 each). The control group (CG) was not exposed to EMW. In contrast, the experimental group (EG) was subjected to continuous exposure to EMW at a whole-body specific absorption rate (SAR) of 1.74 W.kg-1 for 24 hours daily from gestational day (GD) 1 to 19. On GD 20, all mice were euthanized, and body weight, oxidative stress biomarkers, and uterine histological parameters were assessed. Maternal body weight at termination showed a significant reduction in EG compared with CG (p < 0.05). However, differences in overall body weight gain, malondialdehyde (MDA), and superoxide dismutase (SOD) levels were not statistically significant (p > 0.05). Histological evaluation revealed marked alterations: endometrial scores were significantly higher in EG (3.32) than in CG (0.56) (p < 0.05), and myometrial scores were elevated in EG (1.72) versus CG (0.64). Endometrial thickness was reduced in EG (0.748 mm) compared with CG (1.470 mm) (p < 0.05), whereas myometrial thickness showed no significant difference. Continuous EMW exposure (24 h.day-1, GD1–GD19; SAR 1.74 W.kg-1) was associated with lower maternal weight at GD20, reduced litter size, higher endometrial/myometrial injury scores, and reduced endometrial thickness, while MDA and SOD differences were not statistically significant (p > 0.05). These findings warrant further studies to clarify the mechanisms involved without overstating the changes in oxidative biomarkers.
Co-Authors Akhmad Ismail Antari, Arlita Leniseptaria Ariyani, Bitha Astika Widy Utomo, Astika Widy Bambang Witjahjo Bambang Witjahjo dewi, nasywa laksita Diah Ajeng Purbaningrum Elen, Mircha Restiana Eva Annisa Eva Annisaa Fanti Saktini Handoyo, Regenio Akira Heri Sutanto Ika Pawitra Miranti Indah Saraswati Labai, Nikita Ferren Mochtar, Arufiadi Anityo Neni Susilaningsih Pratiwi, Ela Nur Purbaningrum, Diah A. Ratna Damma Purnawati Sherlin Mentary Farizha Sunarno Sunarno Surati Surati Susilaningsih , Neni