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Journal : Journal of Midwifery

Pathophysiology of Preeclamsia Hudila Rifa Karmia; Joserizal Serudji
Journal of Midwifery Vol 7, No 1 (2022): Published on June 2022
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.7.1.94-102.2022

Abstract

The uncertainty of the etiology and underlying mechanisms of the pathophysiology of this disease makes causal structuring and primary prevention of preeclampsia impossible, making it difficult to control morbidity and mortality, both maternal and perinatal. From the many theories on preeclampsia, the disease can be classified into Placental preeclampsia, maternal preeclampsia, and Vascular Disorders of Pregnancy (VDP). Increased inflammatory response to placental factors, excessive inflammatory response to placental factors, and primary vascular disorders are the basis of distinction and also the basis of pathophysiology among the three forms of preeclampsia.
Fetus Cardiovasculler Yusrawati yusrawati; Muhammad Iqbal; Reyhan Julio azwan; Bobby Indra Utama; Joserizal Serudji; Hudila rifa karmia
Journal of Midwifery Vol 7, No 1 (2022): Published on June 2022
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.7.1.24-34.2022

Abstract

Formation of the human heart involves complex biological signals, interactions, specification of myocardial progenitorcells, and heart tube looping. To facilitate survival in the hy poxemic intrauterine environment, the fetus possessesstructural, physiological, and functional cardiovascular adaptations that are fundamentally different from the neonate. The  fetal  circulation is considered to anatomical and biochemical changes in the cardiovascular system. This review article describes key cardiac progenitors involved in embryonic heart development; the cellular, physiological, and anatomical changes during the transition from fetal to neonatal circulation.