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All Journal Sari Pediatri Paediatrica Indonesiana Bioscientia Medicina : Journal of Biomedicine and Translational Research Contagion: Scientific Periodical Journal of Public Health and Coastal Health Science Midwifery Bioscientia Medicina : Journal of Biomedicine and Translational Research
Rinang Mariko
Bagian Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Andalas/RSUP Dr. M. Djamil, Padang
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Peran Sistem Skoring Hematologi dalam Diagnosis Awal Sepsis Neonatorum Awitan Dini Ranti Adriani; Eny Yantri; Rinang Mariko
Sari Pediatri Vol 20, No 1 (2018)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (108.876 KB) | DOI: 10.14238/sp20.1.2018.17-23

Abstract

Latar belakang. Sepsis neonatorum awitan dini (SNAD) merupakan penyebab utama kesakitan dan kematian pada neonatus. Adanya gejala klinis yang tidak spesifik dan keterbatasan sarana pemeriksaan penunjang masih merupakan masalah dalam diagnosis sepsis. Sistem skoring hematologi (SSH) dapat digunakan sebagai metode deteksi awal SNAD. Tujuan. Mengetahui apakah sistem skoring hematologi (SSH) dapat digunakan dalam diagnosis awal SNAD.Metode. Penelitian ini merupakan penelitian cross sectional dan uji diagnostik pada bayi dengan risiko dan diduga sepsis neonatorum awitan dini yang dirawat di NICU/Perinatologi RSUP Dr. M Djamil Padang dari bulan Oktober 2016 hingga Juni 2017. Diagnosis sepsis ditegakkan berdasarkan pemeriksaan klinis dan biakan darah. Sistem skoring hematologi terdiri delapan parameter hematologis.Hasil. Subjek penelitian 78 pasien, terdiri dari tidak sepsis 30 orang (38%) sepsis klinis 28 orang (36%) dan terbukti sepsis 20 orang (26%). Nilai SSH tidak sepsis lebih rendah dari kelompok sepsis klinis dan terbukti sepsis. Tidak terdapat perbedaan yang bermakna nilai SSH kelompok terbukti sepsis dan sepsis klinis. Nilai SSH ≥2 memiliki nilai sensitifitas 100%, spesifitas 25,8 % dalam mendiagnosis sepsis (bakteremia ) pada bayi dengan dugaan SNAD. Kesimpulan. Sistem skoring hematologi ini dapat digunakan sebagai metode deteksi awal sepsis neonatorum awitan dini, terutama di rumah sakit dengan sarana pemeriksaan penunjang terbatas.
Uji Diagnostik Pemeriksaan Antigen Nonstruktural 1 untuk Deteksi Dini Infeksi Virus Dengue pada Anak Megariani Megariani; Rinang Mariko; Amrin Alkamar; Andani Eka Putra
Sari Pediatri Vol 16, No 2 (2014)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp16.2.2014.121-7

Abstract

Latar belakang. Di negara tropis dan subtropis, dengue adalah masalah kesehatan utama. Diagnosis dini sangat penting untuk manajemen infeksi dengue. Nonstruktural 1 merupakan pendekatan baru terhadap diagnosis dengue. Pemeriksaan rapid NS1 dilakukan untuk deteksi dini infeksi virus dengue pada anak.Tujuan. Menentukan nilai diagnostik NS1 mencakup sensitivitas, spesifisitas, nilai duga positif, nilai duga negatif, dan keakuratan NS1 untuk deteksi dini infeksi virus dengue.Metode. Dilakukan penelitian cross sectional terhadap 50 orang anak demam hari ke-1, ke-2 atau ke-3 dengan tes tourniquet positif pada bulan April sampai Desember 2012. Rapid test NS1 dilakukan untuk dibandingkan dengan RT PCR sebagai gold standard.Hasil. Didapatkan 50 orang anak dengan demam dan tes tourniquet positif. Duapuluh lima anak NS1 positif dan 26 RT PCR positif. Rapid test NS1 memiliki sensitivitas 92,3%, spesifisistas 95,8%, nilai duga positif 96 %, nilai duga negatif 92 %, dan keakuratan 94%.Kesimpulan. Rapid test NS1 mempunyai sensitivitas dan spesifisitas yang tinggi untuk deteksi dini infeksi virus dengue pada anak.
Perbedaan Laktat Serial Syok Terkompensasi dengan Syok Dekompensasi pada Sindrom Syok Dengue Ivan Haria Chandra; Rinang Mariko; Firman Arbi
Sari Pediatri Vol 20, No 2 (2018)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (107.153 KB) | DOI: 10.14238/sp20.2.2018.90-94

Abstract

Latar belakang. Tahapan syok sindrom syok dengue (SSD) menurut WHO terbagi dua, yaitu SSD terkompensasi dan dekompensasi. Pada SSD terjadi gangguan perfusi yang mengakibatkan hipoksia jaringan dan peningkatan produksi laktat. Kadar laktat darah dapat digunakan sebagai marker yang dapat membedakan severitas infeksi dengue.Tujuan. Untuk mengetahui perbedaan laktat serial syok terkompensasi dan syok dekompensasi pada pasien SSD. Metode. Penelitian ini merupakan studi cross sectional yang dilakukan pada Januari 2016-Januari 2017 di bangsal anak RSUP Dr. M Djamil. Sampel dikumpulkan secara consecutive sampling. Sampel dibagi atas dua kelompok, yaitu SSD terkompensasi dan dekompensasi. Setiap sampel dilakukan pemeriksaan laktat secara serial dengan alat Accutrend lactate meter, yaitu pada jam ke-0(L1), ke-6(L2), ke-12 (L3), dan ke-24 (L4). Kadar Laktat disebut hiperlaktatemia bila didapatkan nilai >2 mmol/L. Data dianalisis dengan t-test independen.Hasil. Sampel 40 orang, setiap kelompok 20 sampel. Kadar laktat tertinggi terdapat pada L1. Peningkatan kadar laktat darah pada kelompok SSD terkompensasi dan dekompensasi berturut turut mencapai 4,7+0,97 mmol/L dan 6+1,64 mmol/L. Perbandingan kedua kelompok didapatkan perbedaan bermakna (p<0,05) pada rerata kadar laktat darah L1. Tidak didapatkan perbedaan bermakna kedua kelompok pada rerata kadar laktat darah L2, L3,L4 (p>0,05).Kesimpulan. Kadar laktat didapatkan hiperlaktemia pada setiap pemeriksaan laktat serial. Rerata kadar laktat pada kelompok SSD dekompensasi lebih tinggi dibandingkan terkompensasi dengan perbedaan yang bermakna dan didapatkan pada awal penerimaan di rumah sakit.
Profil Klinis, Laboratorium, dan Serologi Infeksi Virus Dengue pada Bayi Rinang Mariko; Sri Rezeki S. Hadinegoro
Sari Pediatri Vol 16, No 6 (2015)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.535 KB) | DOI: 10.14238/sp16.6.2015.441-6

Abstract

Latar belakang. Kejadian infeksi virus dengue (IVD) meningkat di Sumatera Barat pada beberapa tahunterakhir. Bahkan, terjadi pada anak usia kurang dari satu tahun. Bayi mempunyai karakteristik klinik yangunik dan tidak banyak penelitian mengenai hal ini di Indonesia.Tujuan. Mengetahui profil klinis, laboratorium, dan serologi infeksi virus dengue pada bayi yang dirawatdi RSUP Dr. M Djamil Padang dari tahun 2012-2014Metode. Seri kasus menggunakan data rekam medik bayi yang dirawat di RSUP Dr M Djamil Padang dari1 Januari 2012 sampai 31 Desember 2014. Data mencakup usia, jenis kelamin, hari demam saat diagnosis,gejala dan tanda klinis, serta laboratorium.Hasil. Duabelas bayi dengan usia termuda 3 bulan dan usia terbanyak 5 bulan (5/12). Muntah merupakangejala tambahan yang paling banyak ditemukan (9/12), diikuti oleh ptekie dan syok (6/12), serta batuk(5/12). Infeksi primer didapatkan pada 8/12 bayi.Kesimpulan: Rerata usia dan kelompok usia terbanyak 5 bulan. Muntah merupakan gejala yang banyakditemui, diikuti, petekie, batuk dan syok sebagian besar merupakan infeksi primer.
Soluble vascular cell adhesion molecule-1 levels and severity of dengue hemorrhagic fever in children Nolitriani Nolitriani; Rinang Mariko; Mayetti Mayetti
Paediatrica Indonesiana Vol 61 No 6 (2021): November 2021
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi61.6.2021.328-35

Abstract

Background The clinical manifestations of dengue infection vary widely, ranging from asymptomatic to severe forms that can cause death. In severe infections, the expression of soluble vascular cell adhesion molecule-1 (sVCAM-1) in endothelial cells is reportedly excessive, causing endothelial cell gaps through VE-cadherin and plasma leakage, which is the basic mechanism for shock in dengue hemorrhagic fever (DHF). Objective To determine the association between sVCAM-1 levels and severity of dengue hemorrhagic fever in children. Methods This cross-sectional study was done in children with DHF at Dr. M. Djamil Hospital, Padang, West Sumatera. Subjects were diagnosed according to the 2011 WHO criteria and selected by consecutive sampling. They were grouped as DHF with or without shock. Examination of sVCAM-1 levels was done by ELISA method. Mann-Whitney test with a significance of P<0.05 was used for statistical analysis. Results A total of 66 patients were collected from January 2018 to December 2019, but 2 patients were excluded. The 64 subjects who met the inclusion criteria consisted of 32 (50%) DHF without shock and 32 (50%) DHF with shock. Median sVCAM-1 was significantly higher in the DHF with shock group (840 ng/mL) than in DHF without shock group (598 ng/mL) (P<0.05). Conclusion There was a significant association between higher sVCAM-1 levels and greater severity of dengue hemorrhagic fever in children.
The Relationship between Accurate Use of Antibiotics and Clinical Improvement of Sepsis in Neonates Using the Gyssens Method in the Perinatology Ward of Dr. M. Djamil General Hospital, Padang Indonesia Freidlander Pangestu; Rinang Mariko; Didik Hariyanto
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 12 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i12.621

Abstract

Background: Neonatal sepsis is a major cause of neonatal morbidity and mortality in developing countries. Inappropriate use of antibiotics causes an increase in antibiotic resistance, so the Gyssens method is needed, which is a qualitative method and is used to evaluate the use of antibiotics. This study aims to determine the relationship between the accuracy of the use of antibiotics using the Gyssens method on the clinical improvement of neonates in the Perinatology Ward of Dr. M. Djamil General Hospital Padang, Indonesia. Methods: This study used a cross-sectional conducted from January 2020 to December 2020. The study subjects were 67 neonates diagnosed with sepsis in the perinatology ward of Dr. M. Djamil General Hospital, Padang Indonesia. Data analysis was performed with SPSS for univariate and bivariate analysis. Results: Most neonatal sepsis occurs in male infants who have low birth weight. Most cultures do not grow. There was an improvement in clinical and hematological parameters to the administration of first-line, second-line, and culture-appropriate antibiotics according to the Gyssens method, but statistically not significant (p-value > 0.05). The rational use of antibiotics was 89.6%. Conclusion: There is a relationship between the accuracy of antibiotic use on clinical improvement and blood parameters of neonatal sepsis patients in the Perinatology ward of Dr. M. Djamil General Hospital based on the Gyssens method, but it is not statistically significant. The use of antibiotics based on the Gyssens method at Dr. M. Djamil General Hospital is quite good.
The Relationship between Accurate Use of Antibiotics and Clinical Improvement of Sepsis in Neonates Using the Gyssens Method in the Perinatology Ward of Dr. M. Djamil General Hospital, Padang Indonesia Freidlander Pangestu; Rinang Mariko; Didik Hariyanto
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 12 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i12.621

Abstract

Background: Neonatal sepsis is a major cause of neonatal morbidity and mortality in developing countries. Inappropriate use of antibiotics causes an increase in antibiotic resistance, so the Gyssens method is needed, which is a qualitative method and is used to evaluate the use of antibiotics. This study aims to determine the relationship between the accuracy of the use of antibiotics using the Gyssens method on the clinical improvement of neonates in the Perinatology Ward of Dr. M. Djamil General Hospital Padang, Indonesia. Methods: This study used a cross-sectional conducted from January 2020 to December 2020. The study subjects were 67 neonates diagnosed with sepsis in the perinatology ward of Dr. M. Djamil General Hospital, Padang Indonesia. Data analysis was performed with SPSS for univariate and bivariate analysis. Results: Most neonatal sepsis occurs in male infants who have low birth weight. Most cultures do not grow. There was an improvement in clinical and hematological parameters to the administration of first-line, second-line, and culture-appropriate antibiotics according to the Gyssens method, but statistically not significant (p-value > 0.05). The rational use of antibiotics was 89.6%. Conclusion: There is a relationship between the accuracy of antibiotic use on clinical improvement and blood parameters of neonatal sepsis patients in the Perinatology ward of Dr. M. Djamil General Hospital based on the Gyssens method, but it is not statistically significant. The use of antibiotics based on the Gyssens method at Dr. M. Djamil General Hospital is quite good.
Determinant analysis of infant’s basic immunization visits during the covid-19 pandemic Rionitara Wikarya; Roza Sriyanti; Rinang Mariko
Science Midwifery Vol 10 No 6 (2023): February: Midwifery and Health Sciences
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i6.1069

Abstract

The COVID-19 pandemic had an impact on the implementation of health programs, especially immunization services. This is certainly a risk for the occurrence of PD3I Extraordinary Events. The coverage of basic immunization in Padang City was so far from the national basic immunization target that has been set were 95%, coverage of BCG immunization (74.6%), DPT-HB-HIB immunization (55.5%), polio immunization (49%) and MR immunization (46%). Health behavior, especially basic immunization, can be influenced by several determinants. This study aims to determine the determinants of basic immunization visits for infants during the COVID-19 pandemic in the West Rawang Health Center, Padang City working area. This research was a quantitative approach with a cross-sectional design. This research was conducted from January to November 2022. The total sample was 206 mothers with children aged 12-28 months in the Rawang Barat Health Center working area. The sampling technique used proportional random sampling. Data were collected through questionnaires and univariate, bivariate, and multivariate analyses were performed. The results of the study on the determinants of the infant’s basic immunization visits during the COVID-19 pandemic in the Rawang Barat Health Center working area, namely mother's knowledge (p-value<0.001), socioeconomic (p-value 0.444), family support (p-value<0.001), healthcare professionals support (p-value<0.001). The dominant factor related was the mother's knowledge (OR 24,301). The conclusion of this study that there was a significant correlation between maternal knowledge, family support, and health worker support but socioeconomic factors had no significant correlation with basic immunization visits for infants during the COVID-19 pandemic, and the most dominant factor related was the mother's knowledge
Relationship Of Maternal Nutrition Status And Mother's Height Of Stunting Events In Tolls At Puskesmas Pagambiran Annisa Namirah Nasution; Vaulinne Basyir; Rinang Mariko; Nur Afrainin Syah; Yusri Diannne Jurnalis; Hudila Rifa Karmia
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 5, No 1 (2023): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v5i1.14973

Abstract

Abstract Stunting is a chronic malnutrition problem characterized by height for age which is <-2 SD according to the median standard of child growth. Stunting causes poor quality of human resources, which will reduce productivity. The factor causing the problem of stunting In Tools AtPagambiran Health Center, Padang City is the lack of clean water sanitation. The purpose of this study was to determine the relationship between the nutritional status of the mother, the height of the mother, and the mother's knowledge of the incidence of stunting in toddlers at the Pagambiran Health Center, Padang City.This research is an observational analytic study with a cross-sectional design. This research was conducted at the Pagambiran Health Center in Padang City with 3457 populations in November 2021-December 2022. The research sample was 174 mothers and children aged 24-59 months. Sampling using Stratified Random Sampling and Simple Random Sampling. Data collection used a questionnaire and the MCH handbook. The statistical tests used are Chi-square and Logistic Regression.The results of the univariate study found that 55 mothers (31.6%) had a history of chronic energy deficiency, and 12 mothers (6.9%) had a height < 150 cm. The results of the bivariate study using chi-square analysis obtained the p-value of each variable, namely the mother's nutritional status (p=0.005) and mother's height (p=0.018). The study concludes that there is a relationship between the mother's nutritional status and the mother's height in the incidence of stunting in toddlers at the Pagambiran Health Center, Padang City. Researchers suggest that counseling related to stunting can be carried out for pregnant women and prospective brides as an initial preventive measure. Keywords: Chronic Energy Deficiency, Mother's Height, Stunting.
Co-Authors Amrin Alkamar Andani Eka Putra Annisa Namirah Nasution Didik Hariyanto Eny Yantri Firman Arbi Freidlander Pangestu Hudila Rifa Karmia Ivan Haria Chandra Mayetti Mayetti Megariani Megariani Nolitriani Nolitriani Nur Afrainin Syah Ranti Adriani Sri Rezeki S. Hadinegoro Vaulinne Basyir Wikarya, Rionitara Yanti, Roza Sri Yusri Diannne Jurnalis