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All Journal Jurnal Kesehatan Prima Jurnal Analis Medika Biosains (JAMBS) Jurnal Ilmiah Wahana Pendidikan Gemakes: Jurnal Pengabdian Kepada Masyarakat Journal of Indonesia Laboratory Students (JILTS)
Iswari Pauzi
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Religion Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Jurnal Analis Medika Biosains (JAMBS)

 1 
Hubungan Titer Widal Dengan Jumlah Limfosit Dan Trombosit Pada Pasien Demam Typhoid Di Puskesmas Gunungsari Lombok Barat Fitriyani Fitriyani; Iswari Pauzi; Yudha Anggit Jiwantoro
Jurnal Analis Medika Biosains (JAMBS) Vol 8, No 2 (2021): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v8i2.245

Abstract

Demam typhoid merupakan infeksi bakteri yang disebabkan oleh Salmonella typhi. Infeksi Salmonella typhi bersifat bakterimia yang masuk ke dalam usus halus kemudian menyebar ke sumsum tulang. Diagnosis Samonella typhi menggunakan uji widal dan pemeriksaan darah rutin. Uji Widal dan pemeriksaan darah rutin untuk melihat mekanisme tubuh terhadap limfosit dan trombosit yang diproduksi di sumsum tulang dan berfungsi sebagai pertahanan tubuh terhadap adanya infeksi. Bila bakteri ini sampai ke sumsum tulang maka akan menghambat pembentukan limfosit dan trombosit. Hal ini juga disebabkan adanya endotoksin dari bakteri sehingga pada kasus demam typhoid terjadinya limfositosis dan trombositopenia. Tujuan penelitian: Mengetahui hubungan titer widal dengan jumlah limfosit dan trombosit pada pasien demam typhoid. Metode penelitian: Observasional Analitik. Jumlah sampel yang digunakan sebanyak 24 sampel dengan menggunakan data primer. Data yang dikumpulkan berupa titer widal dengan jumlah limfosit dan trombosit. Kemudian diolah menggunakan uji statistik Korelasi Person. Hasil Penelitian: Rerata limfosit pada antigen O dengan titer 1/160 adalah 24,84%, titer 1/320 adalah 43,95%, rerata trombosit dengan titer 1/160 adalah 312.000 µL dan titer 1/320 adalah 230.750 µL. Sedangkan pada antigen H rerata jumlah limfosit dengan titer 1/160 adalah  35,48% dan titer 1/320 adalah 39,86%. Rerata jumlah trombosit dengan titer 1/160 adalah 196.670 µL dan titer 1/320 adalah 158.000 µL. Hasil uji statistik p>0,05. Kesimpulan: Tidak terdapat hubungan titer widal dengan jumlah limfosit dan trombosit pada pasien demam typhoid di Puskesmas Gunungsari Lombok Barat.
Resistance Analysis Of Several Antibiotics in Samples of Clinical Isolates With Salmonellosis Shohifatul Wahyuni; Iswari Pauzi; Yunan Jiwintarum; Fihiruddin Fihiruddin
Jurnal Analis Medika Biosains (JAMBS) Vol 11, No 1 (2024): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v11i1.357

Abstract

Typhus is a systemic infection caused by Salmonella typhi bacteria, which is usually transmitted through contaminated food or drink, usually treated with antibiotics. Inappropriate use of antibiotics causes various problems, one of which causes resistance. This resistance problem has become a global problem, including in Indonesia where there is an increase in bacterial resistance from 2013 which is 40%, 2016 as much as 60% and in 2019 reached 60.4%, due to irrational use of antibiotics so that bacteria become resistant to drugs. This study aims to determine the description of resistance to several antibiotics in clinical isolates of patients with Salmonellosis This study is a pre-experimental study, with a cross sectional approach. The samples used were pure isolates of Salmonella typhi bacteria obtained from blood samples of Salmonellosis patients, then tested for resistance with 5 different types of antibiotics (Ciprofloxacin, Amoxicillin, Levofloxacin, Cefotaxime and Sulfamethoxazolle-trimethopim) with the disk method (Kearby Beaure). The number of experimental units is 25 units, with the number of replications is 5 replications. The results showed that the five types of antibiotics were sensitive to Salmonella typhi bacteria with the highest antibiotic sensitivity being Ciprofloxacin while the antibiotic that had the lowest sensitivity was Amoxicillin. From the results, it can be concluded that the resistance test of the five antibiotics (Ciprofloxacin, Amoxicillin, Levofloxacin, Cefotaxime and Sulfamethoxazolle-trimethopim) is sensitive. 
Co-Authors Agus Muliadi Asrorul Azizi Bachtiar Ardiansyah Erna Kristinawati Fihiruddin Fihiruddin Fitriyani Fitriyani Haryanti, Alya Joni Rokhmat Maruni Wiwin Diarti Muh. Zaini Hasanul Muttaqin Muhammad Sarjan Muhammad Yamin MULIA RASYIDI Nurul Inayati Pusaka, Semerdanta Rindu Rahmatiah Sahputri, Maulidia Rohmiati Shohifatul Wahyuni Siti Rif’ah Sabariah Sudirman Sudirman Urip Wiadnya, Ida Bagus Rai Yudha Anggit Yudha Anggit Jiwantoro Yunan Jiwintarum Yusran Khery