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All Journal ILMU KELAUTAN: Indonesian Journal of Marine Sciences Alchemy : Journal of Chemistry Jurnal Prima Edukasia JPS Unimus Elkawnie Lantanida Journal CIRCUIT: Jurnal Ilmiah Pendidikan Teknik Elektro Al-Kimia Jurnal Ilmiah Didaktika : Media Ilmiah Pendidikan dan Pengajaran Walisongo Journal of Chemistry JKPK (Jurnal Kimia dan Pendidikan Kimia) Jurnal Biomedika Amina Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Measurement In Educational Research Jurnal Natural
Anjar Purba Asmara
Universitas Islam Negeri Ar-Raniry Banda Aceh
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences Other

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Journal : Elkawnie

 1 
Analysis of Vitamin C Level Contained in Mango Gadung (Mangifera indica L) With Varied Retention Time Anjar Purba Asmara
Elkawnie: Journal of Islamic Science and Technology Vol 2, No 1 (2016)
Publisher : Universitas Islam Negeri Ar-Raniry Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/ekw.v2i1.658

Abstract

This research is aimed to determine the level of vitamin C in the mango Gadung which stored as long as 0 days; 1 day; 2 days; and 3 days. It is used iodimetric titration. Standard iodine solution used as titrant while starch as the indicator. Determination of raw normality iodine standardization carried out by titration of iodine with sodium thiosulphate solution primer. Normality primary sodium thiosulphate solution (0.0125 N) are determined through standardized sodium thiosulphate with potassium dichromate. Levels of vitamin C in the fruit is determined by linear regression analysis were made based on the graph of the vitamin C levels versus volume of iodine standard solution which used in the titration. The curve gives the equation as following: y = 413.8 x – 1.238. Levels of vitamin C of mango Gadung which has varied retention time as follows: 0.26% (0 days); 0.22% (1 day); 0.20% (2 days); and 0.16% (3 days).
Analisis Hubungan Kuantitatif Struktur Dan Aktivitas Senyawa Turunan Triazolopiperazin Amida Menggunakan Metode Semiempirik AM1 Anjar Purba Asmara; Mudasir Mudasir; Dwi Siswanta
Elkawnie: Journal of Islamic Science and Technology Vol 1, No 2 (2015)
Publisher : Universitas Islam Negeri Ar-Raniry Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/ekw.v1i2.525

Abstract

QSAR studies had done on derivatives of triazolopiperazine amide as inhibitors DPP IV enzyme that causes diabetes mellitus type 2. The studies had began by modeling the structures of the derivatives of triazolopiperazine amide and calcutating the descriptors of QSAR by semiempirical AM1 method which available on HyperchemÒprogram. QSAR analysis had done by multilinear regression method analysis which is available on SPSSÒprogram using electronic and molecular parameters. The best QSAR equation model for method of semiempirical AM1:-log IC50 =  152.252 + (18,.295*qC1) + (2.343*qC5) + (2263.448*qC9) +  (1662.252*qC10) – (350.806*qC15) + (639.687*qO25)+ (6.515*EH)n = 18; r2 = 0.712; adjusted r2 = 0.510; Fhit/Ftab = 1.124; PRESS = 0.006 The main side of the compound can be determined through the equation. It can be used to study in preventing the disease of DM2 by inhibiting of enzyme DPP IV.
Penentuan Metode Komputasi Untuk Analisis Hubungan Kuantitatif Struktur dan Aktivitas Senyawa Turunan Triazolopiperazin Amida Anjar Purba Asmara; Mudasir Mudasir; Dwi Siswanta
Elkawnie: Journal of Islamic Science and Technology Vol 1, No 1 (2015)
Publisher : Universitas Islam Negeri Ar-Raniry Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/ekw.v1i1.515

Abstract

Penentun metode komputasi untuk analisis hubungan kuantitatif struktur dan aktivitas (HKSA) telah dilakukan pada senyawa turunan triazolopiperazin amida sebagai inhibitor enzim DPP IV yang merupakan penyebab diabetes melitus tipe 2 (DM2). Metode komputasi yang digunakan untuk analisis ini adalah metode semiempirik. Analisis dilakukan dengan pemodelan struktur senyawa turunan triazolopiperazin amida dan perhitungan deskriptor HKSA dilakukan menggunakan program Hyperchem. Parameter yang digunakan adalah pergeseran kimia 13C NMR, panjang ikatan antaratom, sudut ikatan antaratom, dan muatan atom bersih. Hasil perhitungan parameter tersebut dibandingkan dengan data empiris dan hasil perhitungan metode ab initio. Hasil penelitiannya menunjukkan bahwa metode semiempirik yang sesuai untuk analisis HKSA senyawa turunan triazolopiperazin amida adalah AM1 dan PM3.
Co-Authors Agus Dwi Ananto, Agus Dwi Siswanta Edi Istiyono Elsa Citra Lestari Endaruji Sedyadi Fitra Saputra Hanik Khuriana Amungkasi Hernawan Hernawan Ilham Nasrullah Ilma Fistannisa Zette Mahrizal Mahrizal Malahayati Malahayati Mudasir Mudasir Mudasir Mudasir Muhammad Ridwan Harahap Nizar Mauliza Nokman Riyanto Nokman Riyanto Nurhayati Nurhayati Nurhayati Nuzlia, Cut Rahmah, Maulidia Reni Silvia Nasution Rosi Minarty Sabarni Sabarni Sabarni Ummul Karimah Vera Yuli Erviana Winda Afriani Yeniza