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ANALISIS HKSA SENYAWA ANTIDIABETIK TURUNAN TRIAZOLOPIPERAZIN AMIDA MENGGUNAKAN METODE SEMIEMPIRIK PM3 Asmara, Anjar Purba; Mudasir, Mudasir; SIswanta, Dwi
ALCHEMY Vol 5, No 4 (2017): ALCHEMY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (469.18 KB) | DOI: 10.18860/al.v5i4.4045

Abstract

Analisis hubungan kuantitatif struktur dan aktivitas (HKSA) dilakukan untuk senyawa turunan triazolopiperazin amida untuk menghibisi enzim DPP IV penyebab diabetes melitus tipe 2. Analisis ini dilakukan dengan pemodelan molekul turunan triazolopiperazin amida dan perhitungan deskriptor HKSA menggunakan metode semiempirik PM3 dengan program HyperchemÒ. Analisis data menggunakan metode analisis regresi multilinear untuk parameter elektronik dan molekular dengan program SPSSÒ. Persamaan terbaik yang diperoleh adalah:-log IC50 = 79,955 - (11,635*qC1) - (2,094*qC2) - (34,6*qN11) + (797,684*qC15) + (0,288*m) n = 18; r = 0,714; adjusted r2 = 0,305; Fhit/Ftab = 1,239; PRESS = 0,017.Berdasarkan persamaan tersebut, senyawa dengan aktivitas terbaik yang diusulkan adalah:((2R)-4-Okso-4-[3-(Trifluorometil)-5,6-dihidro[1,2,4]triazolo[4,3-a]pirazin-7(8H)-il]-1-(2-fluoro-4,6-dihidroksofenil)butan-2-aminadengan harga –log IC50 = 8,601.
PENENTUAN BILANGAN PEROKSIDA MINYAK RBD (REFINED BLEACHED DEODORIZED) OLEIN PT. PHPO DENGAN METODE TITRASI IODOMETRI Yeniza; Asmara, Anjar Purba
AMINA Vol 1 No 2 (2019): August 2019
Publisher : Department of Chemistry, Faculty of Science and Technology, UIN Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.811 KB) | DOI: 10.22373/amina.v1i2.39

Abstract

This study aims to determine the quality of RBD olein produced by PT. PHPO according to the peroxide number which refers to SNI 01-3741-2002. The sample used is a yellow liquid fraction obtained by fractionation of RBD palm oil or crude palm oil CPO which has undergone a refining process. The sample was analyzed using the iodometric titration method. The results of the calculation of the average peroxide number of RBD olein oil is 0.282 mg O2 / 100 g. Based on these data, Olein RBD oil meets the company quality standard and SNI 01-3741-2002.
PENILAIAN HASIL BELAJAR SISWA DALAM PEMBELAJARAN KIMIA MATERI KIMIA UNSUR MENGGUNAKAN MIND MAP DI KELAS XII IPA SEMESTER 1 SMA NEGERI 1 WONOSARI Anjar Purba Asmara
Lantanida Journal Vol 3, No 1 (2015)
Publisher : UIN AR-RANIRY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1020.993 KB) | DOI: 10.22373/lj.v3i1.1438

Abstract

This research is aimed to determine the quality of mind maps which have created by students and to determine the result of students learning in chemistry lesson by using mind map model. The research uses description qualitative method. The population is students of natural science program grade XII at SMA 1 Wonosari years 2013/2014. The sample consists of 96 students at class XII IPA1, XII IPA2, and XII IPA3. The research gives imformation about the quality of student’s mind map which have scored by using mind map scoring rubric and the result of students learning which have tested by giving daily examination. The percentage of very good category, good category, and good enough category is 40%, 40%, and 20% respectively. The average of test value is 80.406, it means that the average value is higher than minimal passing standart. The percentage of student which pass the test is 80.208%. thus the result to be categorized as good level.
PENGEMBANGAN MEDIA AUDIO VISUAL TENTANG PRAKTIKUM REAKSI OKSIDASI REDUKSI DAN ELEKTROKIMIA SEBAGAI MEDIA PEMBELAJARAN MANDIRI BAGI SISWA SMA/ MA KELAS XII SEMESTER 1 Anjar Purba Asmara; Agus Dwi Ananto; Nokman Riyanto
Lantanida Journal Vol 2, No 2 (2014)
Publisher : UIN AR-RANIRY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (386.006 KB) | DOI: 10.22373/lj.v2i2.1406

Abstract

The research is aimed to develop media of chemistry learning which based on technolgy and information esspecially for student of SMA/ MA grade XII semester I and to determine the value of quality of the media by scoring from chemistry teacher in SMA Yogyakarta Regency. The process of developing media through reviewing by learning media expert and also by peer reviewer. The instument for evaluating to the media is questioner which containing several aspects and criteria of evaluation and scoring. The scoring had done by five chemistry teachers of SMA/ MA in Yogyakarta Regency. There are eight aspects of evaluation and scoring with thirty six indicator of scoring items. The form of the result of evaluation is qualitative data that must be converted into quantitative data for determining of the media’s quality. The product of the research is media audio visual for practicum of oxidation reduction reaction and electrochemistry for student of SMA grade XII semester 1. The components of the product are using guidance to the media, student activity part, evaluation part, the answer of student activity, and also the profile of the researcher. Based on evaluation and scoring from the teachers, the media is reached level of quality as very good level with average score as much as 145.52 where the ideal score is 144. Based on the research, the media could be used to help student to learn chemistry in SMA/MA grade XII semester 1 chapter oxidation and reduction reaction and electrochemistry
The Effect of Seaweed Combination on the Extract of Robusta Coffee (Coffea robusta) Waste Extract in Producing Facial Mask Products Muhammad Ridwan Harahap; Nizar Mauliza; Anjar Purba Asmara; Elsa Citra Lestari; Winda Afriani
Biomedika Vol 13 No 1 (2020): Jurnal Biomedika
Publisher : Fakultas Ilmu Kesehatan Universitas Setia Budi Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/biomedika.v13i1.745

Abstract

Aceh is one of the biggest coffee producers in Indonesia’s province. The coffee farmers separate the coffee beans with the flesh of the fruit for processing the seeds, while the coffee fruit is considered as waste used as animal feed. Based on existing research, the coffee flesh produced contains polyphenol compounds as antibacterial. A very promising sea product from Aceh is seaweed. Brown seaweed (Sargassum sp.) is very common in the west coast of Aceh province. One of the derivatives is alginate. In this study, a combination of polyphenols extracts from coffee flesh and alginates from seaweed Sargassum sp. used as a basic ingredient in making face masks. Tests on organoleptic observations, pH testing, testing time of dried preparations, and testing of bacterial activity have been carried out in this study. In addition, variations in the mixture preparation based on the particle size of alginate powder have also been carried out in this study. The results obtained indicate that the yield produced from coffee fruit extracts is 5.86%, the highest yield of alginate is by potassium carbonate of 40.77%, the acidity of the combination is 4.5 - 6.5. For preparations, drying time has an average estimated time of approximately 6 minutes. Bacterial activity test showed that K2CO3 extracting agent concentration of 2% was strong against bacterial growth with a clean area of ​​14 mm. With these results, it can be seen the combination is able to inhibit the rate of bacterial growth, so it is recommended for alternative ingredients in the manufacture of cosmetics pharmaceutical industry masks.
Pengukuran Radiasi Kalor pada Beberapa Bohlam yang Berbeda Warna Nurhayati Nurhayati; Fitra Saputra; Anjar Purba Asmara; Malahayati Malahayati
CIRCUIT: Jurnal Ilmiah Pendidikan Teknik Elektro Vol 5, No 1 (2021)
Publisher : PTE FTK UIN Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/crc.v5i1.8342

Abstract

This study aims to compare the rate of heat absorption in black, red, green, yellow, milky white, and blue electrical light related to temperature change with a predetermined time variation. This study uses an AC power circuit to light a bulb with varied colours and then measures the temperature associated with the heat involved in the light on. The calculation in this study uses the Black principle concept. The results showed that black and green light bulbs had the greatest temperature change followed by red, blue, yellow, and white bulbs. This is in accordance with the basic concept that dark colours tend to conduct heat better than bright colours.
Uji Fitokimia Senyawa Metabolit Sekunder Dalam Ekstrak Metanol Bunga Turi Merah (Sesbania grandiflora L. Pers) Anjar Purba Asmara
Al-Kimia Vol 5 No 1 (2017): June
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v5i1.2856

Abstract

A beginning investigation about the presence of secondary metabolite compounds in the methanol extract of red grandiflora flower (Sesbania grandiflora L. Pers) has been conducted. The flower which traditionally used as antihyperglycemic therapy has been extracted through methanolic-maceration. The crude extract was phytochemically analyzed by qualitative approach with specific reagent for the each type of the compound. The analysis of functional group prediction is also performed by using FTIR spectrometer. Phytochemical test showed that it contains alkaloid, tannin, polyphenol, flavonoid, quinone, and triterpenoid. The IR spectrum showed that the typical functional group of the secondary metabolite consist of hydroxide (–OH), olefin (C=C), and aromatic which as constituents of phenolic group
Kajian Kinetika Pengaruh Lama Penyimpanan Terhadap Kadar Vitamin C Pada Buah Apel Malang (Malus Sylvestris) Anjar Purba Asmara; Hanik Khuriana Amungkasi
Al-Kimia Vol 7 No 2 (2019): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (371.575 KB) | DOI: 10.24252/al-kimia.v7i2.8125

Abstract

An analysis for determining kinetics of effect of varied shelf-life time to the level of vitamin C in Malus sylvestris fruits has been conducted. It has used fresh apple Malang (M. sylvestris) from Batu (East Java) at their harvest time with the same size and color as the subject of the research. Therefore, the fruits were stored in room temperature and kept away from direct sunlight for 0, 1, 2, and 3 days. The fruits were extracted by using a juice blending technique with aquadest as the solvent. An iodimetric titration has been used to determine the effect of the varied storage time to the level of vitamin C in the samples. The result shows that the average value of vitamin C level in M. sylvestris stored in 0, 1, 2, and 3 days as much as 2.3904 mg/50g; 2.1073 mg/50g; 2.06695 mg/50g; and 1.9860 mg/50g, respectively. Statistic analysis of ANAVA-A and t-test confirms that there are significant differences between the level of vitamin C of M. sylvestris stored in 0, 1, 2, and 3 days. The conclusion about the kinetics of ascorbic acid degradation of M. sylvestris at 27 0C states three expressions as following as: the reaction is a second order reaction, the constants of reaction rate is 2.65 x 10-2 L(mol.days)-1, the half life is 15.786 days, and kinetics model for the reaction is C = (0.0265t + 1/C0)-1.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS AUDIO VISUAL TENTANG PEMBUATAN KOLOID Anjar Purba Asmara
Jurnal Ilmiah Didaktika Vol 15, No 2 (2015): Jurnal Ilmiah DIDAKTIKA Februari 2015
Publisher : Center for Research and Publication Universitas Islam Negeri (UIN) of Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/jid.v15i2.578

Abstract

This is a developing research of learning media which aimed to create media of audio visual for the practicum of colloid and to get quality score of the media. The creating of the media has been consulted by two experts of media and three peer reviewers. The research instrument is questionnaire that contains aspects and criteria of quality scoring. The scoring had been given by five chemistry teachers at excellent senior high school. The result of the research is a audio visual media which burnt on CD. It contains practicum about making of colloid by disperse method and condentation method. Based on the scoring from reviewer 1, the media is classified to good quality with the mean score is 138.5. The media is classified to very good quality by scoring from reviewer 2. By testing in classroom, colloid learning by using audio visual media gives more satisfy result than learning without the media.
Characteristics of Liquid Product of Alkaline Treated Sargassum polycystum C.A. Agardh. from Lange Beach, Aceh Anjar Purba Asmara; Endaruji Sedyadi; Ilma Fistannisa Zette
ILMU KELAUTAN: Indonesian Journal of Marine Sciences Vol 25, No 2 (2020): Ilmu Kelautan
Publisher : Marine Science Department Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.05 KB) | DOI: 10.14710/ik.ijms.25.2.57-65

Abstract

Sargassum is known to have potential ingredients, such as essential nutrients and minerals, which are important for agroindustry and the environment. This study aims to determine the proximate properties of Sargassum polycystum C.A. Agardh from Lange beach and the optimum extraction period arising the liquid product. The dried seaweed was extracted using 0.1% KOH at a constant temperature of 80°C for 120–600 mins. Furthermore, nutrients content, pH, electrical conductivity (EC) and total dissolved solids (TDS) of the afforded filtrate were quantified. As a result, the moisture, ash, fibre, carbohydrate, protein, and fat content were 7.16, 13.057, 20.33, 51.77, 6.12, and 1.57%, respectively. The value of pH, EC, and TDS ranged around 4.69–7.27, 0.013–0.078 dS.m-1, and 6.24–39.75 mg.L-1, respectively. The level of N, P, K, and organic C, were estimated around 0.30–0.81, 0.16–0.28, 0.15–0.20, and 0.32–0.80%, respectively. Meanwhile, the content of Na, Mg, Ca, Fe, Mn, and Zn were observed from 112.04–212.61, 24.60–33.57, 146.59–280.92, 416.22–630.69, 18.25–27.73, and 19.86–26.53 ppm, respectively. In conclusion, extraction for 120 mins seems to be preferable, as the observed parameters were above the minimum range.