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SAHLAN, MUHAMAD
Department Of Chemical Engineering, Faculty Of Engineering, Universitas Indonesia, Kampus UI Depok 16424, Indonesia. Research Center For Biomedical Engineering, Faculty Of Engineering, Universitas Indonesia, Kampus UI Depok 16424, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences

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Journal : Communications in Science and Technology

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Tooth spray with active ingredients casein phosphopeptide – amorphous calcium phosphate (CPP – ACP) and ethanolic extract propolis (EEP) to inhibit tooth demineralization Sahlan, Muhamad; Purwanti, Lucia
Communications in Science and Technology Vol 1 No 2 (2016)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.1.2.2016.24

Abstract

Dental caries is a disease caused by the microbial infection that produces localized damage to the tissue classification. The process begins by demineralization in hard tissue followed by damage to the organic material. Dental caries happens because of demineralization without balanced by remineralization. In this study, tooth powder spray and tooth liquid spray was made with active ingredients of 10% w/w CPP-ACP (Casein Phosphopeptide - Amorphous Calcium Phosphate) and EEP (Ethanolic Extract Propolis), with the variation of 0%, 2%, and 4% w/w EEP in each preparation to inhibit demineralization. Each preparation should pass organoleptic and viscosity study to maintain the quality. pH of each preparation was evaluated to ensure that each preparation has pH above the critical pH of the oral environment. The stability of polyphenol as the antibacterial agent was evaluated for a month to assure the bioavailability in the preparations. The result shows that each preparation has enough organoleptic aspect and proper viscosity. pH level in each preparation is stable above critical pH of mouth environment (5.5), it ranges between 6.5 – 7.12. Polyphenol content in each preparation is stable with highest polyphenol content in tooth powder spray of 4% EEP, i.e. 1.39 – 1.45% (w/w). Qualitative evaluation of tooth morphology by SEM shows that preparations can inhibit enamel demineralization relatively to negative control.
Antifungal activity of microcapsule propolis from Tetragonula spp. to Candida albicans Pratami, Diah Kartika; Indrawati, Teti; Istikomah, Iis; Farida, Siti; Pujianto, Paksi; Sahlan, Muhamad
Communications in Science and Technology Vol 5 No 1 (2020)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (591.231 KB) | DOI: 10.21924/cst.5.1.2020.178

Abstract

Propolis is a mixture of resin and saliva of Tetragonula spp. that have antifungal activity. The purpose of this study was to develop spray-dried microcapsule propolis (SDMP) and to analyze its antifungal activity to Candida albicans. The SDMP was obtained using a spray drying method by maltodextrin and gum arabic coating. The antifungal activity of SDMP of rough propolis (taken from the outside beehive) and smooth propolis (taken from the inside beehive) was analyzed. The macroscopic characterization showed that SDMP has a powder form with brownish-yellow color. The microscopic characterization showed SDMP has a spherical uniform particle shape with particle size 9.32 - 14.61 µm. The encapsulation efficiency of smooth and rough SDMP was 81.22% and 83.04%; moisture content 5.58% and 5.84%; water solubility 98.19% and 98.31%, respectively. The microbial inhibitory concentration to C. albicans was the diameter of 6.33±1.5 to 10±2.5 mm. SDMP displayed remarkable activity in the assays against C. albicans.
Co-Authors Abdul Mun’im Adra Amalia Nur Ahlina Alya Fadhila Ismail AMARILA MALIK ANGGI KHAIRINA HANUM HASIBUAN Anondho Wijanarko Araz Meilin Asep Bayu Budiman Bela Christina, Diana Chulasiri, Malyn Deti Purwanti Diah Kartika Pratami Diana, Akso Dienayati, Dara Dwi Anggar Yusika Dwiranti, Astari Geraldine, Vanessa Hakamada, Kazuaki Hamdi, Darul Hanif Yuliani Hanifi, Muhammad Heri Hermansyah Hertanto, Robby Hiroshi Hashimoto Istikomah, Iis izzul islam Kamila, Etri Dian Kaysa Faradis Mahira Khayrani, Apriliana Cahya Kuntadi Kuntadi, Kuntadi Lischer, Kenny MUHAMMAD IQBAL Nadhifa Tazkia Ramadhani Nidaan Khafian Noguchi, Keiichi NUNUK WIDHYASTUTI Nur Elistiani Eksadita NURUL AZIZAH Perdani, Meka Saima Pujianto, Paksi Purwanti, Lucia Purwanto, Didik B. Putri, Dwini Normayulisa Putrika, Afiatry Ratna Yuniati RIKA RAFFIUDIN Ryo Miyata Sari Honda Sari, Siska Yuliana Satyapertiwi, Dwiantari Shigenori Kumazawa SISWA SETYAHADI Siti Farida Sri Rahayu, Amy Yayuk Sugiarta, Gede Yuda Teguh Pambudi Teti Indrawati TRI BASTUTI PURWANTINI Wiseso, Anggoro Yelin Adalina Yohda, Masafumi Yoshinobu Ishikawa YUKI DESIANDINI Zahra, Soraya