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All Journal MPI (Media Pharmaceutica Indonesiana) Jurnal Farmasi Indonesia JFIOnline Jurnal Mandala Pharmacon Indonesia Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Biomedika PREPOTIF : Jurnal Kesehatan Masyarakat J-ABDIPAMAS (Jurnal Pengabdian Kepada Masyarakat) Jurnal Kesehatan Farmasi
Keswara, Yane Dila
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Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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Journal : JFIOnline

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Tonic Effects Test of Pegagan (Centella asiatica L.) Syrups on White Male Mice Sunarti, Sunarti; Keswara, Yane Dila; Purnamasari, Nuraini Dewi
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 8, No 2 (2016)
Publisher : Indonesian Research Gateway

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Abstract

Centella asiatica L., or known as pegagan leaf, empirically can be used as a tonic for organs such as liver, kidneys and brain. It also can increase memory. In our society, Centella asiatica L., hasn’t been optimally processed as atonic. Commonly, it is processed by boiling or grating the leaf. Raw consumption of this leaf inflicts bad taste. The aim of this research is to find out tonic effect and determine the effective dose of herbal syrup Centella asiatica L. The effect of tonic can be determined using natatory exhaustion method, by observing stimulant effect of a certain drug to an animal.Methods : This research used male mice were divided into 5 groups of treatment. The first group: negative control without herbal syrup Centella asiatica L., substance, positive control 50 mg/kg body weight, first dose group 120 mg/kg mice’s body weight, second dose group 150 mg/kg mice’s body weight and third dose group 180 mg/kg mice’s body weight. The effect of tonic was observed through the increasing duration of the mice’s self-defense ability when it was swum.Result: This research resulted that the use of herbal syrup Centella asiatica L., gave tonic effect on dose 120 mg/kg mice’s body weight, 150 mg/kg mice’s body weight, and 180 mg/kg mice’s body weight. The most effective dose of the use of herbal syrup Centella asiatica L., is on dose 180 mg/kg mice’s body weight.
Tonic Effects Test of Pegagan (Centella asiatica L.) Syrups on White Male Mice Sunarti, Sunarti; Keswara, Yane Dila; Purnamasari, Nuraini Dewi
Jurnal Farmasi Indonesia Vol 8, No 2 (2016)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (296.933 KB) | DOI: 10.35617/jfi.v8i2.518

Abstract

Centella asiatica L., or known as pegagan leaf, empirically can be used as a tonic for organs such as liver, kidneys and brain. It also can increase memory. In our society, Centella asiatica L., hasnâ??t been optimally processed as atonic. Commonly, it is processed by boiling or grating the leaf. Raw consumption of this leaf inflicts bad taste. The aim of this research is to find out tonic effect and determine the effective dose of herbal syrup Centella asiatica L. The effect of tonic can be determined using natatory exhaustion method, by observing stimulant effect of a certain drug to an animal.Methods : This research used male mice were divided into 5 groups of treatment. The first group: negative control without herbal syrup Centella asiatica L., substance, positive control 50 mg/kg body weight, first dose group 120 mg/kg miceâ??s body weight, second dose group 150 mg/kg miceâ??s body weight and third dose group 180 mg/kg miceâ??s body weight. The effect of tonic was observed through the increasing duration of the miceâ??s self-defense ability when it was swum.Result: This research resulted that the use of herbal syrup Centella asiatica L., gave tonic effect on dose 120 mg/kg miceâ??s body weight, 150 mg/kg miceâ??s body weight, and 180 mg/kg miceâ??s body weight. The most effective dose of the use of herbal syrup Centella asiatica L., is on dose 180 mg/kg miceâ??s body weight.
Co-Authors A.A. Ketut Agung Cahyawan W Aditya P, Avianti Eka Dewi Damayanti, Distia Dewi Ekowati Fitriarahmah, Giyan Ghani Abhi Majid Gunawan Pamuji Widodo Hafidah, Hafidah Hapsari, Fitriana Nur Ika Purwidyaningrum Iktsiroh, Firna Fauzul Jason Merari Peranginangin Laksmita, Meirisa Mona Meta Kartika Untari Muhamad Ansory, Hery Purnamasari, Nur Aini Dewi Purnamasari, Selin Aprilliana Purwoko, Agus Putri, Uthia Narida Reiza, Zenita Sri Rejeki Handayani Sunarti Sunarti Sunarti Sunarti Sunarti Supriyadi Waty, Carolina Eka Widyaningrum, Riana