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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya JURNAL PHOTON Collaborative Medical Journal (CMJ) Klinikal Sains (Jurnal Analis Kesehatan) Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Jurnal Pengabdian Masyarakat Multidisiplin Medfarm: Jurnal Farmasi dan Kesehatan Community Empowerment
Eliya Mursyida
Universitas Abdurrab
Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Health screening for the elderly at Lembah Sari, Rumbai Timur Eliya Mursyida; Hotmauli Hotmauli; Alfin Surya
Community Empowerment Vol 8 No 3 (2023)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ce.8204

Abstract

Elderly is the age of someone over 60 years who has decreased physiological function of the body causing non-communicable diseases such as hypertension, arthritis, stroke, chronic obstructive pulmonary disease (COPD), diabetes mellitus (DM), and so on. This service aims to conduct health checks on the elderly in RW 09, Lembah Sari Village, Rumbai Timur as an early detection of non-communicable diseases. The method of implementing community service begins with direct assessment of the elderly accompanied by follow-up of the results of the health screening. The results of the service found that 11 elderly with hypertension, 2 elderly with high diabetes, and 6 elderly with high cholesterol.
Formulation and Antibacterial Evaluation of Liquid Soap Containing Pineapple Peel Extract Against Staphylococcus aureus and Streptococcus pyogenes Eliya Mursyida; Frengki Molek Wirajaya; Olvaria Misfa
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 15 No 1 (2026): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v15i1.765

Abstract

The increasing prevalence of antimicrobial resistance highlights the need for alternative antibacterial agents, particularly against Gram-positive pathogens such as Staphylococcus aureus and Streptococcus pyogenes. Pineapple peel (Ananas comosus (L.) Merr.), an agricultural by-product, contains bioactive compounds with reported antimicrobial activity. This study aimed to formulate ethanol extract of pineapple peel into a liquid soap and evaluate its physicochemical properties and antibacterial effectiveness. The extract was incorporated at concentrations of 5%, 10%, and 15%. Physicochemical evaluations included organoleptic properties, homogeneity, pH, free alkali content, and specific gravity. Antibacterial activity was determined using the agar well diffusion method against S. aureus and S. pyogenes. All formulations met general quality requirements for liquid soap preparations, with pH values ranging from 7.3 to 9.7, specific gravity between 1.01 and 1.04g/mL, and free alkali content ≤0.1%. Antibacterial testing demonstrated a concentration-dependent increase in inhibition zone diameter. The 15% formulation exhibited the highest activity, producing inhibition zones of 13.30mm against S. aureus and 20.25mm against S. pyogenes, with statistically significant differences compared to lower concentrations (p < 0.05). These findings indicate that pineapple peel extract can be successfully incorporated into a stable liquid soap formulation while retaining its antibacterial activity. The 15% formulation shows promising potential as a natural-based antibacterial cleansing product.
Aktivitas Antibakteri Ekstrak Etanol Kulit Nanas (Ananas comosus L. Merr.) terhadap Staphylococcus aureus dan Streptococcus pyogenes: Suatu Penelitian In Vitro Eliya Mursyida; Frengki Molek Wirajaya; Santi Widiasari
Klinikal Sains : Jurnal Analis Kesehatan Vol. 13 No. 2 (2025): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v13i2.6965

Abstract

Skin and soft tissue infections caused by S. aureus and S. pyogenes remain a significant public health concern, particularly in tropical regions. Pineapple peel (Ananas comosus [L.] Merr.), an abundant agricultural by-product, contains several bioactive compounds such as flavonoids, tannins, saponins, and bromelain, which are known for their antibacterial properties. This study aimed to evaluate the antibacterial activity of the ethanol extract of pineapple peel against S. aureus and S. pyogenes. This in vitro experimental study employed a post-test-only control group design. The extract was prepared by maceration using 96% ethanol and diluted with DMSO to obtain final concentrations of 5%, 10%, and 15%. Antibacterial activity was assessed using the well diffusion method on Mueller-Hinton Agar, with 70% ethanol as the positive control and DMSO as the negative control. Inhibition zones were measured after 24 hours of incubation at 37°C. The ethanol extract exhibited inhibitory effects against S. aureus with mean inhibition zone diameters of 4.72±0.88mm (5%), 5.53±0.75mm (10%), and 8.31±1.11mm (15%), and against S. pyogenes with 4.34±0.53mm (5%), 6.20±0.73mm (10%), and 9.29±0.36mm (15%). Statistical analysis using the Kruskal–Wallis test showed significant differences among treatment groups (p < 0.05), confirming that the antibacterial effect was concentration-dependent. In conclusion, the ethanol extract of pineapple peel demonstrated significant antibacterial activity against S. aureus and S. pyogenes, with increasing efficacy at higher concentrations, suggesting its potential as a natural antibacterial agent for future therapeutic or topical applications.
DETEKSI BAKTERI COLIFORM DAN ESCHERICHIA COLI DARI AIR MINUM JAJANAN ANAK DI SALAH SATU SEKOLAH DASAR KOTA PEKANBARU Eliya Mursyida; Yulnefia Yulnefia
Collaborative Medical Journal Vol 1 No 2 (2018): Mei
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (361.134 KB)

Abstract

Kebutuhan air sangat penting bagi tubuh manusia karena air merupakan komposisi terbesar zat pembentuk tubuh yaitu 68% dari bagian tubuh manusia. Persediaan air untuk keperluan rumah tangga harus cukup, baik dari segi kualitas maupun kuantitasnya. Penelitian ini bertujuan untuk mengetahui adanya bakteri Coliform dan Escherichia coli (E. coli) dari air minum jajanan anak di salah satu Sekolah Dasar (SD) Kota Pekanbaru. Penelitian ini menggunakan metode deskriptif kualitatif didasarkan kepada Most Probable Number (MPN) dan reaksi biokimia. Berdasarkan hasil penelitian yang dilakukan didapatkan hasil bahwa pada air minum jajanan anak di salah satu Sekolah Dasar Pekanbaru terkontaminasi Coliform dengan nilai MPN air mineral (1) 240/100 ml, air sachet (1) 0/100 ml, air mineral (2) >1100/100 ml, dan air sachet (2) >1100/100 ml. Air mineral (2) dan air sachet (2) teridentifikasi E. coli pada medium Eosin Methylene Blue (EMB) dengan koloni hijau metalik. Sehingga secara mikrobiologis air minum jajanan anak sekolah dasar tersebut tidak layak untuk dikonsumsi berdasarkan Keputusan Direktur Jenderal Pengawasan Obat dan Makanan Nomor: 03726/B/SK/VII/89 tentang batas maksimum MPN Coliform dalam minuman ringan dan sari buah adalah 20 koloni/100 ml sampel dan jumlah E. coli harus 0 koloni/100 ml sampel air minum.
DETEKSI BAKTERI COLIFORM DAN ESCHERICHIA COLI DALAM SUSU KEMASAN YANG DISIMPAN PADA SUHU BERBEDA Eliya Mursyida; Reny Guspratiwi
Collaborative Medical Journal Vol 2 No 3 (2019): September
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.221 KB)

Abstract

Milk is one food that contains nutritional value that is beneficial to the body, but is easily contaminated by several microbes. One of the microbes found in milk is Escherichia coli (E. coli) which is one of bacteria that causes diarrhea. E. coli strains produce endotoxins as virulence factors, causing disease. This study aims to detect Coliform and E. coli bacteria in packaged milk products stored at different temperatures. The design of this research is descriptive observational with total plate number (ALT) and Most Probable Number (MPN) test methods. Data were analysed descriptively, and presented in tbales and figures. The result obtained indicate that milk stores at room temperature contains bacteria with ALT 3.4x104CFU/mL and MPN values >1100/mL. so it can be concluded that the best temperature in pasteurized milk storage is at the refrigerator temperature.
PENGARUH EKSTRAK ETANOL 96% DAUN JAMBU BIJI (PSIDIUM GUAJAVA L.) TERHADAP KADAR GULA DARAH TIKUS WISTAR JANTAN (RATTUS NOVERGICUS) YANG DIINDUKSI ALOKSAN Reny Guspratiwi; Eliya Mursyida; Yulinar Yulinar
Collaborative Medical Journal Vol 2 No 3 (2019): September
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.226 KB)

Abstract

Diabetes melitus (DM) tipe 2 merupakan tipe diabetes yang paling sering terjadi. Sekitar 90-95% penderita dari keseluruhan kasus diabetes merupakan pengidap DM tipe 2. Penelitian menunjukkan bahwa ekstrak daun jambu biji dapat menurunkan kadar glukosa darah pada penderita DM tipe 2. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol 96% daun jambu biji (Psidium guajava L.) terhadap penurunan kadar glukosa darah tikus Wistar (Rattus norvegicus) jantan yang diinduksi aloksan. Penelitian yang dilakukan bersifat eksperimental dengan rancangan penelitian Randomized post test control group design. Tikus Wistar jantan dibagi menjadi 5 kelompok yaitu normal, kontrol negatif, kontrol positif, ekstrak etanol 96% daun jambu biji dosis 300 mg/kg BB, dan 600 mg/kg BB. Tikus diinduksi aloksan sebanyak 120 mg/kg BB secara intraperitoneal. Perlakuan diberikan sejak hari ke-3 setelah induksi aloksan hingga hari ke-10. Pengamatan kadar glukosa darah dilakukan pada hari ke 5 dan ke-10. Hasil pengukuran kadar glukosa darah tikus pada kelompok positif, ekstrak etanol 96% daun jambu biji dosis 300 mg/kg BB dan 600 mg/kg BB menunjukkan penurunan kadar glukosa darah dibandingkan kelompok negatif. Penurunan yang signifikan ditunjukkan oleh ekstrak etanol 96% daun jambu biji dosis 300 mg/kg BB dibandingkan dengan kontrol negatif dan positif.
UJI AKTIVITAS ANTIFUNGI BAKTERI ASAM LAKTAT ASAL DADIH TERHADAP Fusarium oxysporum Yudiawati Yudiawati; Olvaria Misfa; Eliya Mursyida; Riski Dwi Utami
Collaborative Medical Journal Vol 5 No 2 (2022): Mei
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v5i2.3253

Abstract

Intoksikasi mikotoksin pada manusia disebabkan oleh makanan yang dikonsumsi dan merupakan inhibitor poten terhadap sintesis protein, RNA, dan DNA. Fusarium oxysporum merupakan salah satu spesies penyebab intoksikasi mikotoksin yang ditularkan melalui makanan. Mikroba yang umumnya digunakan untuk eliminasi mikotoksin adalah bakteri asam laktat (BAL) yang bersumber dari makanan fermentasi seperti dadih yang berasal dari fermentasi susu kerbau. Tujuan penelitian ini untuk menguji aktivitas antifungi BAL terhadap pertumbuhan F. oxysporum dan menggunakan desain post-test only with control group. Aktivitas BAL terhadap F. oxysporum diuji menggunakan metode sumuran. Data yang diperoleh dianalisis menggunakan uji One Way ANOVA dan uji Post Hoc Bonferroni. Hasil isolasi BAL dari dadih adalah bakteri Gram positif berbentuk bacil dan coccobaci dengan uji katalase negatif. Diameter zona hambat BAL 1, BAL 2, dan BAL 3 yaitu 9,10 mm, 8,30 mm, 7,33 mm. Hasil uji One Way ANOVA menunjukkan terdapat perbedaan bermakna antara ketiga isolat BAL dalam menghambat pertumbuhan F. oxysporum. Hasil uji Post hoc Bobferroni menunjukkan kontrol positif terdapat perbedaan yang bermakna dengan BAL 1, BAL 2, dan BAL 3. Sedangkan, hasil BAL 1, BAL 2, dan BAL 3 tidak terdapat perbedaan bermakna pada kelompok perlakuan. Hasil menunjukkan bahwa tiga isolat BAL mampu menghambat pertumbuhan Fusarium oxysporum.
UJI AKTIVITAS ANTIFUNGI BAKTERI ASAM LAKTAT ASAL DADIH TERHADAP Aspergillus flavus Olvaria Misfa; Viola Anggraini Asrizal; Eliya Mursyida; Uly Astuti Siregar
Collaborative Medical Journal Vol 6 No 1 (2023): Januari
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v6i1.3254

Abstract

Primary gastrointestinal aspergillosis (AGP) is an inflammation of the gastrointestinal tract from the duodenum to the rectum. Aspergillus flavus (A. flavus) is one of the fungi that causes aspergillosis. This infection occurs due to aflatoxin from A. flavus which can cause damage to the gastric mucosa. The use of antifungals for long-term treatment can cause toxicity effects and also resistance, so alternative treatments are needed. Dadih is a fermented product of buffalo milk which contains lactic acid bacteria (LAB). Lactic acid bacteria produce acetic acid, lactic acid, and bacteriocin which can inhibit the growth of the fungus A. flavus. LAB species capable of suppressing the growth of A. flavus were Lactococcus lactis, Lactobacillus casei subsp. pseudoplantarum and Lactobacillus plantarum, and Lactobacillus brevis. To determine and analyze the antifungal activity of lactic acid bacteria from curd against Aspergillus flavus. This study used a post test-only design with a control group. The sample used was LAB isolate from curd, while the test fungus used was A. flavus. This study begins with rejuvenation of LAB isolates, then classification of LAB and pathogens, as well as inhibition test using the well diffusion method. The data obtained were analyzed using One-Way ANOVA test and Bonferroni Post hoc test.: LAB isolates from curd were Gram-positive bacteria in the form of bacilli and cocobasil, with negative catalse test results. The average diameter of the inhibition zones of LAB 1, LAB 2, and LAB against A. flavus were 8.55mm, 10.23mm, and 6.20mm. The results of the ANOVA test showed that there was a significant difference between the three LABs. The results of the Bonferron Post hoc test showed that there was a significant difference between LAB 2 isolates and positive controls against LAB 3. Meanwhile, there was no significant difference between LAB 2 and BAL 3 isolates against LAB 1 isolates. LAB isolate from curd was able to inhibit the growth of the fungus A. flavus.
Co-Authors Alfin Surya Bellanera Alifia Safitri Fitria Dina Sella Frengki Molek Wirajaya Hotmauli Hotmauli Huda Marlina Wati Marwan, Deinike Wanita Nurmaliza Hasan Olvaria Misfa Raissa Almira Ratih Ayuningtiyas Reny Guspratiwi Reny Guspratiwi Riski Dwi Utami Sabrina Hayati Santi Widiasari Santi Widiasari Sari, Tyagita Widya Siti Hartini Syelvia Moulita Tassya Alfiola Uly Astuti Siregar Viola Anggraini Asrizal Yudiawati Yudiawati Yulinar Yulinar Yulnefia Yulnefia