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Santoso Cornain
Faculty of Medicine, Universitas Indonesia, Jakarta 10430
Medicine & Pharmacology

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Pilot study of food consumption pattern: Assessment of validity of dietary history method Herman, Susilowati; Ohno, Yoshiyuki; Dillon, Drupadi; Cornain, Santoso; Sakamoto, Goi; Darwis, Idral; Wakai, Kenzi; Prihartono, Joedo; Watanabe, Susumu; Soetrisno, Esti; Ramli, Muchlis; Budiningsih, Setyawati; Suzuki, Sadao; Roostini, Endang S.; Tjindarbumi, Didid; Tjahjadi, Gunawan
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (446.558 KB) | DOI: 10.13181/mji.v4i3.916

Abstract

[no abstract available]
Pathological aspects of breast cancer in Indonesian females, emphasizing on the modified W.H.O. classifïcation Tjahjadi, Gunawan; Sakamoto, Goi; Tjindarbumi, Didid; Watanabe, Susumu; Prihartono, Joedo; Ohno, Yoshiyuki; Cornain, Santoso; Soetrisno, Esti; Roostini, Endang S.; Ramli, Muchlis; Darwis, Idral; Budiningsih, Setyawati; Suzuki, Sadao; Kubo, Nakako
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (878.187 KB) | DOI: 10.13181/mji.v4i3.912

Abstract

[no abstract available]
Preliminary analysis of nutritional factors in breast cancer Dillon, Drupadi; Herman, Susilowati; Ohno, Yoshiyuki; Prihartono, Joedo; Cornain, Santoso; Sakamoto, Goi; Ramli, Muchlis; Budiningsih, Setyawati; Suzuki, Sadao; Darwis, Idral; Soetrisno, Esti; Wakai, Kenji; Tjahjadi, Gunawan; Tjindarbumi, Didid; Watanabe, Susumu; Roostini, Endang S.
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (508.043 KB) | DOI: 10.13181/mji.v4i3.917

Abstract

[no abstract available]
Epidemiological analysis of risk factors for breast cancer in Indonesian females Budiningsih, Setyawati; Ohno, Yoshiyuki; Prihartono, Joedo; Ramli, Muchlis; Wakai, Kenji; Cornain, Santoso; Darwis, Idral; Suzuki, Sadao; Tjindarbumi, Didid; Watanabe, Susumu; Tjahjadi, Gunawan; Sakamoto, Goi; Soetrisno, Esti; Roostini, Endang S.
Medical Journal of Indonesia Vol 4, No 3 (1995): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (757.106 KB) | DOI: 10.13181/mji.v4i3.913

Abstract

[no abstract available]
The Significance of HLA-antigens in dermatology Cornain, Santoso
Medical Journal of Indonesia Vol 4, No 1 (1995): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (503.018 KB) | DOI: 10.13181/mji.v4i1.905

Abstract

[no abstract available]
The role of HLA-antigens in Prurigo Hebra Boediardja, Siti A.; S, Moeslichan; Cornain, Santoso; Budimulja, Unandar; Djuanda, Adhi
Medical Journal of Indonesia Vol 9, No 4 (2000): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1133.994 KB) | DOI: 10.13181/mji.v9i4.616

Abstract

[no abstract available]
Clinical-pathologic factors, as predictor of lymph nodes metastasis in cervical cancer stage IB and IIA Aziz, M. F.; Andrijono, Andrijono; Nuranna, Laila; Purbadi, Sigit; Mangunkusumo, Rukmini T.; Siregar, Budiningsih; Cornain, Santoso; Saifuddin, Abdul B.; Tjarta, Achmad; Sutrisna, Bambang
Medical Journal of Indonesia Vol 13, No 2 (2004): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.052 KB) | DOI: 10.13181/mji.v13i2.574

Abstract

The aim of this study was to identify possible predictor factors of lymph node metastases in patients with cervical cancer stage IB and IIA. Study was conducted between May 1996 and December 2001. There were 183 patients of cervical cancer with FIGO Stage IB and IIA who were underwent radical hysterectomy and lymphadenectomy. From those 158 patients could be evaluated, consisting 43 patients with node metastases 115 patients without metastases. Research design was case control study. Case was patients with node metastases and control was those without node metastases. Multivariate analysis was made after bivariate analysis. On bivariate analysis age < 39 years, diameter of lesion > 4 cm, stage IIA > 4 cm, histopathology moderate and poor differentiation, blood and lymphatic vessel invasion were independent variables for node metastases with p value ≤ 0.05. However, on multivariate analysis younger age, parity ≥ 4, diameter of lesion, histopathology adenosquamous, and lymph vascular invasion (+) as independent factors for node metastases with p value ≤ 0.05. Conclusion: Younger age, parity ≥ 4, stage IIA > 4 cm, diameter of lesion, histopathology adenosquamous, and lymph vascular invasion (+) were risk factors for node metastases and can be used as predictors. (Med J Indones 2004; 13: 113-8)Keywords: cervical cancer, radical hysterectomy, node metastases, case control study, predictor
The immunohistopathological features of prurigo Hebra Boediardja, Siti A.; Tjarta, Achmad; Cornain, Santoso; Budimulja, Unandar; Djuanda, Adhi; Roostini, Endang S.; Hartati, Meny
Medical Journal of Indonesia Vol 10, No 1 (2001): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1308.599 KB) | DOI: 10.13181/mji.v10i1.1

Abstract

Until now the pathologic mechanisms of prurigo Hebra (PH) is still understood. Earlier study the genetic inheritance of PH showed the multifactorial pattern. Considering the genetic inheritance and the existence of allergic reaction to insects bite in all patients, might be the mechanisms followed hypersensitivity reactions. The purpose of this study is to evaluate the general and specific local inflammatory features of early and late lesions of prurigo Hebra (PH). Fifty biopsy specimens of early and late lesions of prurigo Hebra patients were processed with haematoxylin-eosin (HE) and immunoperoryde (lP) staining using monoclonal antibodies against specific inflammatory cells namely B cells, T cells, helper T (CD4+) cells, supressor T (CD8+) cells, Langerhans cells, and antigen presenting cells (APC) that expressed HLA-DR antigen. HE-stained specimens: In early lesions, PMN cells were few, while eosinophils were present in great quantity and independent of mast cells and plasma cells; this feature was similar to that of insect bite reaction. IP-stained specimens: In late lesions, the amounts of lympho-histiocytic infiltration consisting of T cells, CD8+ cells, HLA-DR-expressing APCs were greater than those of early lesions, although it was not statistically significant. An exception was for the CD4+ cells, whose number in early lesions was significantly higher. The ratio of CD4+ to CD8+ in early lesions was higher than in late lesions (3/1: 2/1). This suggested that CD4+ cells were predominant. B cells, which were normally absent, appeared in small quantity in both early and late Lesions. The presence of B cells was not statistically correlated with T cells or eosinophils. The number of Langerhans cells in late lesions was higher than in early lesions. There was a strong correlation (r=0.39) between T cells and HLA-DR-expressing antigen-presenting cells (APCs/HLA-DR). Those cells found in great qunntity suggested that PH patients usually expose to extrinsic factors. In some cases with severe condition, the presence of eosinophils was more profound and was statistically significant. It is conclude that  immunohistopathological mechanisms of PH follow the mixed types (one and IV) hypersensitivity reaction. (Med J Indones 2001;10:1-15)Keywords: Prurigo Hebra, eosinophils, CD4+cells, mixed (I and IV) types of hypersensitivity.
E-cadherin and NM23HI as metastasis predictors for various degrees of histological malignancy in invasive ductal carcinoma Rustamadji, Primariadewi; Tjarta, Ahmad; Cornain, Santoso; Ramli, Muchlis; Soetrisno, Esti
Medical Journal of Indonesia Vol 20, No 4 (2011): November
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1660.907 KB) | DOI: 10.13181/mji.v20i4.459

Abstract

Background: This study aims to analyze whether the expressions of E-cadherin and NM23HI can be used as predictors of ductal carcinoma metastasis in various degrees of  malignancies.Methods: Paraffin blocks were obtained from 97 patients with invasive breast ductal carcinoma with malignancy grade 1, 2 and 3 who came to several hospitals in Jakarta and Bandung from 2000 to 2006. Histopathological examinations of hematoxylin eosin slides of primary and secondary tumors were done to  diagnose the degree of histological malignancy and metastasis status. Further, immunohistochemistry staining of E-cadherin, NM23HI and cytokeratin were done followed by scoring according to the number of positive cells and staining intensity. The  associations of E-cadherin and NM23H1 expression with the presence of metastasis and grade of histological malignancy were analyzed.Results: Subjects were 29-75 years old (mean: 48.19 years), with most subjects aged 40–45 years old, with malignancy grade 1, 2 and 3 of 18.56%, 45.36% and 36.1% respectively. There was a significant association between E-cadherin and NM23HI expression in primary tumors. The possibility of invasion and metastasis inhibition by positive E-cadherin and NM23HI was 14 and 11 times respectively compared to those with negative E-cadherin and/ or NM23HI expression. The ROC curve showed that E-cadherin (r= 0.755) and NM23HI (r= 0.827) expressions were strongly associated, sensitive and specific as metastasis markers. However, E-cadherin and NM23HI expression didnot show significant association with histological degree of invasive ductal carcinoma.Conclusion: E-cadherin and NM23HI expressions can be used as invasion and metastasis markers, but cannot be used as  markers for the degree of histological malignancy of invasive ductal carcinoma. (Med J Indones 2011; 20:263-70)Keywords: Breast cancer, E-cadherin, NM23HI
Light and scanning electron microscopic studies of spermatozoa from infertile couples before and after swim up migration Satmoko, Satmoko; Hartamto, Hadi; Cornain, Santoso; Tjokronegoro, Arjatmo
Medical Journal of Indonesia Vol 1, No 2 (1992): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1218.235 KB) | DOI: 10.13181/mji.v1i2.3580

Abstract

[no abstract available]
Co-Authors Abdul B. Saifuddin Abidin Widjanarko Achmad Tjarta Adhi Djuanda Ahmad Tjarta Anak Agung Istri Sri Wiadnyani Andrijono Andrijono Arjatmo Tjokronegoro Arman Muchtar Arman Mukhtar Averdi Roezin Bambang Sutrisna Budiningsih Siregar Didid Tjindarbumi Djajadiman Gatot Drupadi Dillon Drupadi S. Dillon Dyonesia Ary Harjanti Endang Hardjolukito Endang S. Roostini Endang Windiastuti Ening Krisnuhoni Ening Krisnuhono Esti Soetrisno Evert D.C. Poetiray Evert Poetiray Goi Sakamoto Gunawan Tjahjadi Hartamto, Hadi Herman Cipto I Made Nasar Idral Darwis Idwal Darwis Iik Wilarso Irwan Ramli Joedo Prihartono Keishi Araki Kenji Wakai Kenzi Wakai Ketut Mulyadi Laila Nuranna M. F. Aziz Masamitsu Ichihashi Masamitsu lchihashi Masato Ueda Meny Hartati Mochtar Hamzah Moeslichan S Mpu Kanoko Muchlis Ramli Nakako Kubo Nobuo Munakata Nurul Akbar Primariadewi Rustamadji R. R. Mangunkusumo Rukmini T. Mangunkusumo Sadao Suzuki Satmoko, Satmoko Setiawati Budiningsih Setyawati Budiningsih Sigit Pribadi Sigit Purbadi Siti A. Boediardja Sonar S. Panigoro Sri M.S. Utami Susilowati Herman Susumu Watanabe Tooru Nagano Unandar Budimulja Wilfried H. Sibuea Yoshiyuki Ohno Yoshiyuki Ohno Ohno