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All Journal JURNAL GIZI INDONESIA Yustisia Smart Medical Journal Jurnal Gizi Klinik Indonesia Kanun: Jurnal Ilmu Hukum Jurnal Epidemiologi Kesehatan Indonesia
Kusmadewi Eka Damayanti
Sebelas Maret University
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Efek pemberian ekstrak klorofil daun pepaya (carica papaya, linn.) terhadap kadar ast dan alt serum Damayanti, Kusmadewi Eka; Wijayahadi, Noor; Puruhita, Niken
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 4, No 1 (2015)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (171.446 KB) | DOI: 10.14710/jgi.4.1.63-66

Abstract

Background: Pharmacological therapy is one of the therapy modalities which carries the hepatic injury as one of its side effects. Nowadays, curcuma tablets has become choice of hepatoprotector. Other substance which has the possibilities of hepatoprotection activities is chlorophyll. The study is aimed to investigate the effect of papaya leaves chlorophyll extracts towards the serum AST and serum ALT levels on high-dose-paracetamol-induced Wistar rats. Materials and methods: This was an experimental study applying pretest-posttest controlled group design. Twenty eight Wistar rats 8-12 weeks age and weighted 185-220 grams assigned into four groups, namely group I (control), group II (paracetamol 750 mg/kg bw + no hepatoprotector agent), group III (paracetamol 750 mg/kg bw + curcuma 100 mg/kg bw), and group IV (paracetamol 750 mg/kg bw + papaya leaves chlorophyll extracts 300 mg/kg bw). The hepatoprotector agents were administered for a week, while the high dose paracetamol was administered for three consecutive days (day 5, 6, and 7). The pretest samples were drawn on the fifth day before the administration of high dose paracetamol, and the posttest samples were drawn on eightth day. Results: There were no difference among four groups on serum AST and serum ALT levels before the administration of high dose paracetamol, p=0.522 dan p=0.682, respectively. After the administration of high dose paracetamol, there were differences among four groups on both variables, both p=0.000. The post-hoc test showed that differences happened on all four groups (p<0.05).Conclusion: Chlorophyll extract of papaya leaves can inhibit liver injury on high-dose-paracetamol-induced-Wistar rats. 
ENHANCING REFUGEE HEALTH AND RIGHTS THROUGH SCREENING: LEGAL AND PUBLIC HEALTH PERSPECTIVES IN INDONESIA Kusumo, Ayub Torry Satriyo; Damayanti, Kusmadewi Eka
Kanun Jurnal Ilmu Hukum Vol 27, No 2: August 2025: Islam and Justice development in Indonesia
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/kanun.v27i2.39289

Abstract

Health has become a primary concern due to the increased vulnerability of refugees to disease, especially in refugee settings where risks of illness are heightened. These environments often expose refugees to higher health threats and can lead to unintentional violations of their basic rights. However, healthcare for refugees has not been adequately addressed, largely due to legal gaps in Indonesias refugee handling policies. This study emphasizes the importance of implementing health and malnutrition screening in refugee settings from both sovereignty and public health perspectives. The research is a literature review of peer-reviewed open-access articles sourced from PubMed and Scopus, using keywords such as malnutrition and refugee setting. Additionally, legal documents relevant to refugee rights, including the 1951 Refugee Convention, international agreements, Presidential Decree 125/2016 on handling refugees from abroad, and other pertinent legal texts, were analyzed to provide a legal framework for the findings. The study reveals that healthcare services in refugee settings are limited and often inaccessible. To address this, it proposes that health and malnutrition screening serve as initial steps to safeguard refugees right to health, grounded in the sovereignty principle. Despite Indonesias non-participation in the 1951 Convention and the 1967 Protocol, protecting public health by preventing disease transmission from refugees aligns with national sovereignty. Therefore, Indonesia, even without formal refugee status recognition, should prioritize health screening and adhere to international Minimum Standards and the principle of National Treatment to ensure the protection of both refugees and the broader community.
Faktor determinan risiko kardiometabolik pada remaja usia 15-18 tahun Wiboworini, Budiyanti; Shabrina, Amalina; Dewi, Yulia Lanti Retno; Sari, Amelya Augusthina Ayu; Handayani, Sutartinah Sri; Damayanti, Kusmadewi Eka; Azzahrah, Aisyah; Tjung, Vivienne
Jurnal Gizi Klinik Indonesia Vol 21, No 1 (2024): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.90010

Abstract

Determinant factors of cardiometabolic risk in adolescents aged 15-18 yearsBackground: Cardiometabolic diseases are increasing worldwide, and the risk of developing them starts as early as adolescence. In the long term, they may lead to comorbidities. Evidence suggests the risk factors of cardiometabolic diseases among adolescents are obesity, excessive food intake, socioeconomic status, breakfast habits, and physical activity, among others. Objective: This study aimed to determine the determinants of cardiometabolic risk in adolescents aged 15-18. Methods: This was a cross-sectional study in Al-Abidin High School Surakarta with 146 study subjects. Cardiometabolic risks were classified using Cardiometabolic Disease Staging (CMDS), waist circumference was measured with Medline, physical activity was measured using a Physical Activity Questionnaire for Adolescents (PAQA), and blood pressure was measured with a sphygmomanometer. Socioeconomic, transportation, and breakfast habits were obtained from the general questionnaire. Chi-square, ANOVA, and logistic regression were then performed using SPSS 23. Results: Gender was significantly associated with cardiometabolic risk (p=0.001). A total of 41.3% of boys were at risk of cardiometabolic (OR=3.964). Socioeconomic, breakfast habits, transportation, and physical activity were not associated with cardiometabolic risk (p>0.05).Conclusion: Boys 15 – 18 years were at a higher risk of cardiometabolic, by 3.694 times greater than girls. Socioeconomic status, breakfast habits, transportation, and physical activity were not correlated with cardiometabolic risk among adolescents.
Evaluasi Metode GeneXpert MTB/RIF dengan Sampel Raw Sputum untuk Mendeteksi Tuberkulosis Paru Susilawati, Tri Nugraha; Saptawati, Leli; Damayanti, Kusmadewi Eka; Larasati, Riska
Jurnal Epidemiologi Kesehatan Indonesia Vol. 2, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tuberkulosis (TB) merupakan penyakit menular yang masih menjadi masalah utama di Indonesia dan dunia. Tantangan utama dalam mendiagnosis TB secara konvensional yaitu rendahnya sensitivitas deteksi pada pemeriksaan mikroskopis dan lamanya waktu yang diperlukan untuk kultur. Penelitian ini bertujuan untuk mengevaluasi metode GeneXpert MTB/RIF untuk mendeteksiMycobacterium tuberculosis dengan sampel dahak langsung di RSUD Dr. Moewardi (RSDM), Surakarta. Analisis observasional dengan pendekatan kohort retrospektif menggunakan data sekunder hasil pemeriksaan GeneXpert MTB/RIF pada sampel dahak langsung di Laboratorium Mikrobiologi Klinik RSDM pada tahun 2012 2015. Sampel didapatkan dari pasien yang memenuhi kriteria suspek multidrug-resistant tuberculosis (MDR-TB) dan sampel tersebut telah dikultur di Balai Laboratorium Kesehatan (BLK), Jawa Tengah. Data dianalisis dengan OpenEpi versi 3, Epi Info 7, dan MedCalc. Pada penelitian ini didapatkan sensitivitas, spesifisitas, nilai duga positif dan negatif (NDP dan NDN) serta akurasi metode GeneXpert MTB/RIF sebesar 93,62%, 27,17%, 68,89%, 71,21%, dan 69,21%. Prevalensi TB paru pada sampel yang diperiksa sebesar 63,27%. Rendahnya spesifisitas GeneXpert MTB/RIF mengindikasikan perlunya kultur sebagai baku emas. Namun demikian, perlu standarisasi pemrosesan sampel dahak dalam segi teknik dan waktu pengambilan sampel disertai data klinis yang memadai untuk melihat riwayat terapi yang telah diberikan pada pasien.
Legal and Health Protection for Creative Economy Actors during The Covid-19 Pandemic Maharani, Andina Elok Puri; Gravitiani, Evi; Purwaningtyas, Niniek; Parwitasari, Tika Andarasni; Kusumo, Ayub Torry Satriyo; Hartanto, Heri; Damayanti, Kusmadewi Eka
Yustisia Vol 10, No 2: August 2021
Publisher : Faculty of Law, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/yustisia.v10i2.49975

Abstract

This research examined Covid-19 from the perspective of legal and health protection by regional governments. Generally, regional governments are at the front line in protecting communities in this autonomy era due to their constitutional obligations. Data also shows that the creative economy actors in the micro, small, and medium business sector constitute over 90% of the workforce, necessitating their protection. This research used empirical-juridical research with an interdisciplinary approach examined the legislation and the community's reality. A Focus Group Discussion (FGD) was conducted with relevant stakeholders and creative economy business actors in Surakarta, Bandung, and Madiun cities. Furthermore, concepts of legal, health, and economic theories were reviewed to formulate a regional government policy draft regarding these business actors during the Covid-19 emergency. The results showed an existing form of legal protection regulation related to health and the economy at the national level. However, three big cities (Bandung, Madiun, and Surakarta) representing three provinces  as research objects are yet to provide regional regulations concerning protection for creative economy actors, though the local government has encouraged an increase in their activities
Relationship between Body Mass Index and Central Fat Accumulation in Adolescents in Surakarta Wijaya, Angellica Eliora; Ayusari, Amelya Augusthina; Wiboworini, Budiyanti; Damayanti, Kusmadewi Eka
Smart Medical Journal Vol 8, No 3 (2025): December
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v8i3.110627

Abstract

Introduction: Obesity diagnosis can be determined through the calculation of body mass index (BMI). However, BMI can only serve as a screening tool for obesity and can not measure fat distribution while waist-to-height ratio (WHtR) is considered better for determining central fat distribution in adolescents. The aim of this study is to examine the relationship between body mass index and central fat accumulation in adolescents in Surakarta.Methods: The method used was cross-sectional, involving measurements of weight, height, and waist circumference. The subjects of this study are tenth-grade adolescents from three high schools in Surakarta, with a total of 83 subjects. The variables in this study are the z-score of BMI-for-age (ratio) with waist circumference (ratio) and waist-to-height ratio (WHtR). Statistical analysis used the Spearman test.Results: The Spearman correlation analysis demonstrated a significant association between body mass index (BMI) and waist circumference (p < 0,001; r = 0,777), as well as BMI and WHtR (p < 0,001; r = 0,785).Conclusion: There is a strong positive relationship between body mass index and central fat accumulation among high school students in Surakarta.Keywords: adolescents; BMI; central fat; waist circumference; WHtR
Co-Authors Agil Wahyu Wicaksono Andina Elok Puri Maharani Ari Natalia Probandari Arsita Eka Prasetyawati Ayub Torry Satriyo Kusumo Ayusari, Amelya Augusthina Azzahrah, Aisyah Budiyanti Wiboworini Dhyani Rahma Sari Dwi Ariono Eric Edwin Yuliantara Evi Gravitiani, Evi Handayani, Sutartinah Sri Heri Hartanto Larasati, Riska Leli Saptawati Niken Puruhita Noor Wijayahadi Parwitasari, Tika Andarasni Purwaningtyas, Niniek Sari, Amelya Augusthina Ayu Shabrina, Amalina Tjung, Vivienne Tri Nugraha Susilawati Wijaya, Angellica Eliora yulia lanti retno dewi