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All Journal Tropical Medicine Journal Jurnal Kesehatan Andalas Jurnal Kesehatan Prima Jurnal Analis Medika Biosains (JAMBS) Anakes: Jurnal Ilmiah Analis Kesehatan

I Gusti Ayu Nyoman Danuyanti

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Author-ID : 249660

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 14 Documents Claim Missing Document

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THE USE OF BLACK SOYBEAN (Glycine max L) EXTRACT AGAINST THE ACTIVITY OF LIVER ENZYMES (AST - ALT) AND ANTIOXIDANT SUPEROXIDE DISMUSTASE (SOD) OF WHITE RAT I Gusti Ayu Nyoman Danuyanti; Ersandhi Resnhaleksmana
Jurnal Kesehatan Prima Vol 12, No 1 (2018): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Strenuous physical activity can increase the activity of enzymes AST (aspartate aminotransaminase) and ALT (alanine aminotransaminase) in the blood as a sign of hepatic dysfunction caused by oxidative stress as a result. Excessive free radicals that damage macromolecules in cells. The supplementation of black soybean (Glycine max L) contains anthocyanin as an antioxidant is expected to reduce the formation of free radicals thus the activity of liver enzymes and the levels of SOD enzymes as intracellular antioxidant can be maintained. The purpose of this study was to determine the effect of using extracts of black soybean (Glycine max L) on the activity of liver enzymes (AST-ALT) and the antioxidant superoxide dismutase (SOD) of white rats that were given a maximum of physical activity. The research was control group post test design in vivo that used black soya extract treatment given to white rats (Rattus norvegicus) Wistar strain given maximum physical activity. The results indicated black soybean extract 40% was the most powerful retaining the activity of liver enzymes and blood levels of antioxidants SOD. The conclusion is there is an effect of black soybean extract against the activity of liver enzymes (AST-ALT) in rats given maximal activity, whereas SOD enzymes can inhibit the decline of SOD enzyme level to 37.8% but statistically there is no significant influence.Keywords: AST-ALT enzymes; antioxidants SOD; Soybean black; Physical activity maximum.

STUDI TOXOPLASMOSIS PADA PENDERITA SCHIZOPHRENIA DI RUMAH SAKIT JIWA PROVINSI NTB Ersandhi Resnhaleksmana; Nursardjan Nursardjan; I Gusti Ayu Nyoman Danuyanti
Jurnal Kesehatan Prima Vol 8, No 1 (2014): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Toxoplasmosis, a disease caused by Toxoplasma gondii, a parasite of humans and animals scattered throughout the world. Infection T. gondii into the body of most real place in the reticuloendothelial tissues and the brain with symptoms of central nervous system often leave residual symptoms, such as mental and motor retardation. This phenomenon often occurs in people with schizophrenia. This study aims to determine the toxoplasmosis in patients with schizophrenia in Rumah sakit jiwa Provinsi NTB. The Methods of This study used an observational analytic design with cross-sectional design to determine the percentage of toxoplasmosis, by examination of the ELISA for determination of IgG T. gondidi serum samples of patients with schizophrenia at Rumah Sakit Jiwa Provinsi NTB. The research was conducted in July-November 2011, with a total sample size is 42 people. The idependent variabel is Toxoplasmosis and the dependent variabel is patient with schizophrenia.There is a percentage of toxoplasmosis in patients with schizophrenia was 54.8% (23 people) with higher levels of IgG T. gondii highest was 300 UI / ml. From the results of this study indicate the presence of infection T. gondii in patients with schizophrenia at Rumah Sakit jiwa Provinsi NTB.

HUBUNGAN KADAR NITRIT OKSIDA (NO) DALAM DARAH TERHADAP RESIKO KEJADIAN DIABETES MELLITUS TIPE 2 DENGAN HIPERTENSI DI RSUP NTB I Gusti Ayu Nyoman Danuyanti; Erna Kristinawati; Ersandhi Resnhaleksmana
Jurnal Kesehatan Prima Vol 8, No 1 (2014): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Diabetes Mellitus (DM) is a group of metabolic diseases with characteristic hyperglycemia that occurs due to abnormalities in insulin secretion, insulin action or both. Pathophysiology of type 2 diabetes mellitus are very complex with involving a variety of factors, including nutrition, obesity, sedentary lifestyle, and lack of physical activity, and genetik. The prolonged of condition hyperglycemia causes endothelial cell dysfunction resulting in decreased production of various compounds that are antithrombotic and vasodilating include nitric oxide ( NO). The purpose of this study was to determine the relationship between levels of nitric oxide (NO) in the blood against the risk of incident type 2 diabetes mellitus with hypertension at the RSUP NTB. This study uses a case-control design, with a sample size of 30 people with type 2 diabetes with hypertension as the case group and 30 patients without hypertension, diabetes mellitus type as the control group. The total sample is 60 people. Dependent variable in this study is the levels of NO in the blood while the independent variables of type 2 DM patients with hypertension. Determination of levels of nitric oxide (NO) in the blood using spectrophotometric methods. Correlation test is used to determine the relationship between levels of nitric oxide (NO) in blood with the blood pressure while Chi-square test used to determine the relationship of NO levels on the risk of incident type 2 diabetes with hypertension. The results showed average mean levels of NO in patients with type 2 diabetes with hypertension was lower than 0.54 μM with type 2 DM patients without hypertension is 1.32 μM. The results of correlation test levels of NO in the blood and blood pressure showed p-value = 0.000 (<α 0.05) and there is a strong relationship with a correlation coefficient value of 0.749 for systolic blood pressure and 0.694 for diastolic. Analysis of the relationship of NO levels in the blood against the risk of incident type 2 diabetes with hypertension show the value of p = 0.000. The overall from the can be concluded There is a relationship between the amount of nitric oxide (NO) in the blood against the risk of incident type 2 diabetes mellitus with hypertension in the RSUP NTB.

SENYAWA PENGKUPLING α-NAFTHILAMIN UNTUK VALIDASI METODE SPEKTROFOTOMETRI PENENTUAN NITRIT (〖〖NO〗_2〗^-) DI DALAM AIR Maruni Wiwin Diarti; I Gusti Ayu Nyoman Danuyanti; I Gede Billy Sumantri
Jurnal Kesehatan Prima Vol 9, No 1 (2015): Jurnal Kesehatan Prima
Publisher : poltekkes kemenkes mataram

Abstract: Validation of analytical methods need to be conducted to determine the feasibility of the method when the method is newly developed or modified. Determination of nitrite in water-based Cupling diazotized reaction has been developed in various fields. Many modifications have been carried out primarily in the selection of the source of the diazonium salt compound or compounds that can cupling. The this study was to determine the validity of the determination of nitrite in water by spectrophotometric method cupling compound α-nafthilamin. This study is a pre-experiments with experimental units and large units based guidelines experimental validation of analytical methods. The results show the value of 0.995 linearity, limit of detection (LOD) 0.039 ppm, 0.882 sensitivity, precision 1.38%, and 100.37% accuracy rate. The conclusion of this study is the method of spectrophotometric determination of nitrite in water using compound α-nafthilamin cupling valid for determining the concentration of nitrite in the water with a minimum detection limit of 0.039 ppm.

Co-Authors Ahmad Hamim Sadewa Erna Kristinawati Ersandhi Resnhaleksmana I Gede Billy Sumantri I Komang Agusjaya Mataram, I Komang Agusjaya Khairunnisa, Nisrina Yola Maruni Wiwin Diarti Ni Putu Agustini Nursardjan Nursardjan Pancawati Ariami Pauzi, Iswari Rahmayanti, Utari Rizki Resnhaleksmana, Ersandhi Resnhaleksmana, Ersandhi Rohmi, Rohmi Sholihah, Ayu Safitri Siti Zaetun Siti Zaetun, Siti Tasmini - Tsamarah, Yumna Tahani Utari Rizki Rahmayanti Widary, Baiq Larasati Yudha Anggit Jiwantoro Yuli Laraeni

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