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Hyponatremia After Intracranial Hemorrhage: Cerebral Salt Wasting Syndrome (CSWS) or The Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)? Wan Novriza Wijaya; Novita Anggraeni; Sony; Andrea Valentino
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 1 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i1.1174

Abstract

Background: Hyponatremia is a common electrolyte disorder encountered in neurosurgical patients, often associated with significant morbidity and mortality. This case report highlights the importance of recognizing and appropriately managing cerebral salt wasting syndrome (CSWS), a rare but important cause of hyponatremia in neurosurgical patients, often following intracranial hemorrhage (ICH). Distinguishing CSWS from the syndrome of inappropriate antidiuretic hormone secretion (SIADH) is crucial for appropriate management. Case presentation: A 56-year-old male with a history of hypertension and diabetes mellitus presented with sudden-onset left-sided weakness and decreased consciousness following an ICH. He underwent a ventriculoperitoneal (VP) shunt placement for hydrocephalus. Post-operatively, he developed hyponatremia with elevated urine sodium levels and hypovolemia, suggestive of CSWS. The patient was treated with fluid replacement therapy, including hypertonic saline, and desmopressin, resulting in improvement in his hyponatremia. Conclusion: CSWS is an important cause of hyponatremia in neurosurgical patients. Prompt diagnosis and appropriate management, including fluid replacement and potentially desmopressin, can improve patient outcomes. This case underscores the need for a high index of suspicion for CSWS in neurosurgical patients presenting with hyponatremia and highlights the importance of careful monitoring and individualized treatment strategies.
Successful Epidural Anesthesia Management in Cesarean Section for a Patient with Eisenmenger Syndrome: A Case Report Abdi Kumala; Novita Anggraeni; Sony
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 2 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i2.1197

Abstract

Background: Eisenmenger syndrome is a rare and complex condition that poses significant challenges for anesthesiologists during pregnancy, particularly during labor and delivery. The physiological changes associated with pregnancy, such as increased cardiac output and blood volume, can exacerbate the hemodynamic instability in these patients. Careful selection of anesthetic techniques and agents is crucial to maintain hemodynamic stability and ensure the safety of both mother and fetus. Case presentation: We present the case of a 34-35-week pregnant woman with Eisenmenger syndrome who underwent a successful cesarean section under epidural anesthesia. The patient's hemodynamic parameters were closely monitored throughout the procedure, and no significant complications were encountered. Conclusion: This case report demonstrates that epidural anesthesia can be a safe and effective option for cesarean section in patients with Eisenmenger syndrome. Meticulous planning, close monitoring, and prompt management of potential complications are essential for a successful outcome.
Anesthetic Management of a Pediatric Patient with Popliteal Pterygium Syndrome Undergoing Labiopalatoplasty: A Case Report Peter Leonardo; Novita Anggraeni; Vera Muharrami
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 2 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i2.1200

Abstract

Background: Popliteal pterygium syndrome (PPS) is a rare congenital disorder characterized by multiple anomalies, including orofacial, musculoskeletal, and genitourinary defects. Airway management in PPS patients can be challenging due to associated craniofacial abnormalities. This case report describes the anesthetic management of a 5-month-old infant with PPS undergoing labiopalatoplasty. Case presentation: A 5-month-old male infant, weighing 5.9 kg, presented for labiopalatoplasty. He had a diagnosis of PPS with associated labiopalatoschisis, ankyloblepharon filiforme, pterygium in the popliteal fossa, cryptorchidism, and syndactyly. Airway assessment revealed a patent airway with a cleft lip and palate. Anesthesia was induced with sevoflurane and maintained with sevoflurane and nitrous oxide. Direct laryngoscopy was unsuccessful, and videolaryngoscopy was used to facilitate tracheal intubation. Conclusion: This case highlights the challenges of airway management in infants with PPS. A thorough preoperative airway assessment and the availability of alternative intubation techniques, such as videolaryngoscopy, are crucial for successful anesthetic management in these patients.
Successful Anesthetic Management of Pheochromocytoma in a Patient with Preoperative Hypertension: A Case Report Faisal Irwanda; Novita Anggraeni
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 3 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i3.1222

Abstract

Background: Pheochromocytoma, a rare tumor arising from chromaffin cells in the adrenal medulla, poses significant anesthetic challenges due to its propensity to release catecholamines, potentially leading to life-threatening hypertensive crises. This case report describes the successful anesthetic management of a patient with pheochromocytoma presenting with preoperative hypertension. Case presentation: A 37-year-old female with a 12x5 cm right adrenal tumor diagnosed as pheochromocytoma was scheduled for adrenalectomy. She presented with a history of uncontrolled hypertension, episodic headaches, diaphoresis, and palpitations. Preoperative management focuses on blood pressure control using alpha and beta-adrenergic blockers. Anesthesia was induced with propofol, fentanyl, and atracurium, while nitroglycerin and sevoflurane were used to maintain hemodynamic stability. The patient's blood pressure was closely monitored throughout the procedure, with interventions made to manage fluctuations during tumor manipulation. Conclusion: Successful anesthetic management of pheochromocytoma requires meticulous preoperative preparation, vigilant intraoperative monitoring, and prompt pharmacological interventions. This case highlights the importance of a multidisciplinary approach, including endocrinologists, anesthesiologists, and surgeons, to optimize patient outcomes.
Successful Anesthetic Management of a Cesarean Section in a Patient with Cardiomyopathy and Cardiogenic Shock: A Case Report Alta Ikhsan Nur; Nopian Hidayat; Novita Anggraeni; Sony
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 3 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i3.1230

Abstract

Background: Cardiomyopathy in pregnancy is a rare but serious condition that can lead to significant maternal and fetal morbidity and mortality. Anesthetic management of these patients is challenging due to the complex interplay of physiological changes and the potential for hemodynamic instability. This case report describes the successful anesthetic management of a cesarean section in a patient with cardiomyopathy and cardiogenic shock. Case presentation: A 29-year-old woman with cardiomyopathy and cardiogenic shock presented for emergency cesarean section at 36-37 weeks gestation. She had a history of global hypokinetic, left ventricular and atrial dilatation, and an ejection fraction (EF) of 32%. She was also in atrial fibrillation. Epidural anesthesia was selected due to its lower risk of complications compared to general anesthesia. The patient was carefully monitored throughout the procedure, and her hemodynamics were maintained with a combination of fluids and inotropes. The surgery was successful, and the patient delivered a healthy baby boy. Conclusion: This case report demonstrates that successful anesthetic management of cesarean section is possible in patients with cardiomyopathy and cardiogenic shock. Careful planning, close monitoring, and a multidisciplinary approach are essential for a positive outcome.
Spontaneous Respiration Intubation as a Cornerstone of Multidisciplinary Management for Delayed Tracheoesophageal Fistula Repair in a Critically Ill Neonate Sulthoni; Dino Irawan; Novita Anggraeni; Nopian Hidayat; T Addi Saputra
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 10 No. 1 (2026): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v10i1.1474

Abstract

Background: The perioperative management of neonates with esophageal atresia and Type C tracheoesophageal fistula (EA/TEF) is exceptionally challenging, particularly in cases of delayed diagnosis complicated by aspiration pneumonia and congenital heart disease. The primary anesthetic risk is catastrophic gastric insufflation and hemodynamic collapse from positive pressure ventilation (PPV) before fistula control. This report details a successful multidisciplinary strategy centered on an airway technique that preserves spontaneous ventilation. Case presentation: A 16-day-old, 2.5 kg female neonate with Type C EA/TEF presented for surgical repair following a delayed referral. The case was critically complicated by severe aspiration pneumonia (cultures positive for Klebsiella pneumoniae), which was managed with targeted antibiotic therapy, and hemodynamically significant congenital heart defects (2.5 mm patent ductus arteriosus, 3 mm patent foramen ovale). After 48 hours of intensive cardiorespiratory and nutritional optimization in the neonatal intensive care unit (NICU), the patient underwent surgery. To circumvent the life-threatening risks of PPV, an inhalational induction with sevoflurane was performed, maintaining spontaneous ventilation. The airway was secured via direct laryngoscopy without neuromuscular blockade. A right extrapleural thoracotomy, fistula ligation, and primary esophageal anastomosis were successfully performed. Intraoperative lung retraction-induced desaturation was managed with coordinated surgeon-anesthetist maneuvers. The postoperative course was uneventful. Conclusion: In a high-risk neonate with delayed TEF presentation and profound cardiorespiratory compromise, securing the airway while maintaining spontaneous ventilation is a cornerstone of safe anesthetic practice. This approach, integrated within a comprehensive, multidisciplinary management plan, directly mitigates the risk of gastric perforation and cardiovascular collapse, thereby enabling a successful surgical repair and favorable outcome.
PENGARUH KEBIJAKAN FISKAL TERHADAP PERTUMBUHAN EKONOMI INDONESIA Muhlis; Novita Anggraeni; Mujito
Indonesian Journal of Social Science and Education (IJOSSE) Vol. 1 No. 1 (2025): Vol. 1 No. 1 Edisi Januari 2025
Publisher : JCI Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/ijosse.v1i1.637

Abstract

Penelitian ini bertujuan untuk menganalisis pengaruh kebijakan fiskal terhadap pertumbuhan ekonomi Indonesia, dengan fokus pada penerimaan pajak, pengeluaran pemerintah, dan defisit anggaran selama periode 2014-2024. Kebijakan fiskal mempengaruhi berbagai aspek perekonomian, termasuk konsumsi dan investasi, yang berdampak pada pertumbuhan ekonomi. Data yang digunakan berasal dari Badan Pusat Statistik (BPS) dan Kementerian Keuangan Republik Indonesia, yang mencakup data PDB tahunan, penerimaan pajak, pengeluaran pemerintah, dan defisit anggaran. Metode analisis yang digunakan adalah regresi linier berganda, dengan uji asumsi klasik untuk memastikan kualitas data. Hasil penelitian menunjukkan bahwa penerimaan pajak memiliki pengaruh signifikan terhadap pertumbuhan PDB, dengan nilai signifikansi sebesar 0,046 yang lebih kecil dari 0,05. Peningkatan penerimaan pajak dapat memperkuat kapasitas fiskal pemerintah untuk mendanai pembangunan, yang pada gilirannya mendorong pertumbuhan ekonomi.
PERSEPSI KONSUMEN TERHADAP FASILITAS DAN DESAIN HOTEL SYARIAH DI JABODETABEK Muhlis; Novita Anggraeni
Indonesian Journal of Social Science and Education (IJOSSE) Vol. 1 No. 3 (2025): Vol. 1 No. 3 : Edisi September 2025
Publisher : JCI Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/ijosse.v1i3.1253

Abstract

Pariwisata halal di Indonesia menunjukkan perkembangan signifikan, ditandai dengan meningkatnya kebutuhan akan akomodasi yang sesuai dengan prinsip syariah. Hotel syariah hadir sebagai jawaban atas kebutuhan wisatawan muslim dengan menyediakan fasilitas ibadah, makanan halal, serta desain yang sesuai ketentuan syariah. Penelitian ini bertujuan untuk menganalisis persepsi konsumen terhadap fasilitas dan desain hotel syariah di wilayah Jabodetabek. Penelitian menggunakan pendekatan kuantitatif dengan metode survei, melibatkan 150 responden yang pernah menginap di hotel syariah. Data dikumpulkan melalui kuesioner terstruktur dan dianalisis menggunakan teknik Weighted Mean Score (WMS) untuk mengetahui tingkat penilaian responden pada setiap indikator. Hasil penelitian menunjukkan bahwa pada aspek fasilitas, responden memberikan penilaian sangat tinggi dengan rata-rata skor 4,760 – 4,880. Fasilitas ibadah, termasuk ketersediaan perlengkapan shalat di kamar dan area bersuci, merupakan aspek yang paling diapresiasi. Pada aspek desain, rata-rata penilaian responden berada di atas 4,300, dengan apresiasi tinggi terhadap tata letak yang memperhatikan arah kiblat serta ketiadaan dekorasi berbentuk makhluk hidup. Namun, pemisahan ruang tunggu atau ruang pertemuan pria dan wanita memperoleh skor relatif lebih rendah (4,127). Temuan ini menegaskan bahwa hotel syariah di Jabodetabek telah memenuhi ekspektasi tamu muslim, meskipun masih perlu perbaikan pada aspek diferensiasi gender untuk memperkuat identitas syariah dan meningkatkan daya saing di industri perhotelan.
ANALISIS PENGARUH HARGA, KEMUDAHAN PENGGUNAAN DAN ULASAN KONSUMEN DARING TERHADAP KEPUTUSAN PEMBELIAN PADA MARKETPLACE TOKOPEDIA DI BOGOR Muhlis; Mujito; Novita Anggraeni; Silma Mausuli
Economicus : Jurnal Ekonomi dan Manajemen Vol. 16 No. 1 (2025): Desember: Economicus : Jurnal Ekonomi dan Manajemen
Publisher : Institut Teknologi dan Bisnis Dewantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47860/economicus.v16i1.222

Abstract

This study aims to analyze the influence of price, ease of use, and online consumer reviews on purchasing decisions at the Tokopedia marketplace in Bogor. The variables studied were price, ease of use, and online consumer reviews as independent variables, while purchasing decisions were the dependent variable. A quantitative approach with a causality research strategy was used, and data was collected from 100 respondents who are Tokopedia users in Bogor using a questionnaire. The data analysis technique used was multiple linear regression analysis. The results showed that price, ease of use, and online consumer reviews each had a significant and positive effect on purchasing decisions. Furthermore, all three variables simultaneously and significantly influence purchasing decisions. The price variable was found to be the most dominant factor influencing purchasing decisions, with a regression coefficient of 0.486. The adjusted R-square value was 0.654, which indicates that 65.4% of the variation in purchasing decisions is explained by the three variables, while the remaining 34.6% is influenced by other variables not included in this study.
AL-TA'ASSUF IN GOVERNMENT REGULATION NO. 45 OF 1990 ARTICLE 4 PARAGRAPH 2 Novita Anggraeni; Ahmad Arief; Andi Muh. Taqiyuddin BN; Abu Sahman Nasim; Taufik, Muh. Bambang
Indonesian Journal of Shariah and Justice Vol. 5 No. 2 (2025)
Publisher : Program Studi Hukum Keluarga dan Hukum Ekonomi Syariah, Program Pascasarjana Institut Agama Islam Negeri (IAIN) Ternate

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46339/ijsj.v5i2.197

Abstract

The purpose of this research is to reveal the indicators of al-Ta'assuf in Government Regulation No. 45 of 1990 Article 4 paragraph 2 and legal solutions to al-Ta'assuf in Government Regulation No. 45 of 1990 Article 4 paragraph 2. This research is qualitative research, the type of research is library research. The data collection method used is literature study, with normative theological, juridical, and sociological approaches. The results showed that;1) The two indicators of al-ta'assuf in the use of rights have been used to analyze Government Regulation No. 45 of 1990 Article 4 paragraph 2. In accordance with the analysis of al-ta'assuf, Government Regulation No. 45 of 1990 Article 4 paragraph 2, should not conclude its provisions by prohibiting civil servant women as polygynous wives absolutely. Because the absolute prohibition will always be understood in any condition and however, without any conditions. 2) The legal solution to al-Ta'assuf in Government Regulation No. 45 of 1990 Article 4 paragraph 2, namely the government as the competent authority in establishing regulations, should pay attention to the greater good by considering the rights of civil servant women and children who are born later.