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All Journal Folia Medica Indonesiana Biomedika Majalah Obstetri dan Ginekologi Health Notions Buletin Farmatera Care : Jurnal Ilmiah Ilmu Kesehatan Majalah Biomorfologi (Biomorphology Journal)

Tirthaningsih, Ni Wajan

Department Of Anatomy, Histology And Pharmacology, Faculty Of Medicine, Universitas Airlangga, Surabaya

Author-ID : 2535409

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Articles

The Profile of Brain Tumor Cases in RSUD Dr Soetomo, Surabaya R. Yuvasanghar Ravindra Mohan; Joni Wahyuhadi; Ni Wajan Tirthaningsih
Health Notions Vol 5, No 2 (2021): February
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn50203

Brain tumor is a condition affecting many people worldwide.Patients often had similar functional neurological symptoms even if the type of tumors diagnosed were entirely different at a later stage.Some of the neurological symptoms were tingling in the feet, changes in eyesight,tremors in the extremities, headaches or migraines and more. Patients who suffer from brain tumor go through a screening process to identify the cause of the problem. Factors such as age and gender was observed in this study which affected the data distribution of brain tumors. This study aimed to find the data distribution of the brain tumor cases in RSUD Dr Soetomo. The results obtained showed that the highest number of brain tumor found were meningiomas followed by unspecified brain neoplasms as the second highest and adenomas being the third highest tumor type found in RSUD Dr Soetomo. The total number of female patients with brain tumor were higher than that of males. The median age of the patients was found to be 45. The highest number of tumor cases were seen in the adult age group followed by teens, children and elderly. The benign tumor type is found to be higher in number as compared to malignant. The number of supratentorial tumors are also found to be higher than infratentorial overall. Keywords: age; gender; brain tumor

Profile study of ectopic pregnancy at Department of Obstetrics and Gynecology, Dr. Soetomo Hospital, Surabaya, Indonesia Andarisa Rachman Nugraha; Ashon Sa’adi; Ni Wajan Tirthaningsih
Majalah Obstetri dan Ginekologi Vol. 28 No. 2 (2020): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V28I22020.75-78

Objective: Ectopic pregnancy is a leading cause of maternal death during the first trimester of pregnancy, it can cause infertility and even death as a result of massive bleeding of the mother. Based on those fact, study of ectopic pregnancy is needed.Materials and Methods: This study used retrospective design and total sampling to collect the data and present it as a descriptive – analytical result.Results: Of the 98 samples, as many as 30.6% of the patients age was in the range of 26 - 30 years, there was 16.3% of patients with unmarried status, hormonal contraception was more often used by patients than intrauterine device, there were 7% of patients with recurrent ectopic pregnancy, as many as 12.1% of patients had a history of surgery in the abdomen or pelvic area, ectopic pregnancy was most common in first pregnancies, and there were 26.4% of patient found with Infection.Conclusion: Ectopic pregnancy has many risk factors, Ectopic pregnancy could be cause by solely one risk factor or more (multifactorial), The most commonly found risk factor was infection.

Body Mass Index, Waist-Hip Ratio and Fasting Blood Glucose Levels amongst the University Students Rury Tiara Oktariza; Viskasari Pintoko Kalanjati; Ni Wajan Tirthaningsih
Folia Medica Indonesiana Vol. 57 No. 1 (2021): March
Publisher : Universitas Airlangga

Overweight and obesity have been correlated to the higher risk for developing metabolic diseases in later life, i.e. DM type 2. We study the body mass index (BMI), the waist to hip ratio (WHR) and the fasting blood glucose levels (FBG) in the seemingly healthy male and female university students to comprehend these variables amongst the youth in Indonesia in 2019. The BMI and WHR of 150 male and female students aged 18-22 years old of the IIKBW, Kediri were measured by standardised anthropometry. The FBG was measured after 8 hours-minimum of fasting from the capillary blood drop using glucometer. Data was then analysed using SPSS 17 with level of significance of p<0.05. According to Asia-Pacific BMI classification, students were 30.7% obese with males significantly higher than females (p=0.016), 18% overweight (significantly higher in females, p=0.04), 36% normal and 15.3% underweight.When compared between genders, the WHR is significantly higher in males (p<0.001); whilst no significant differences in FBG (p=0.6). Four males and 5 females with FBG ≥ 100 mg/dl, whereas others were within normal limits. There are positive significant correlations between BMI and WHR in males and females (r=0.777, p<0.001; r=0.54, p<0.001, respectively). There is a significant positive correlation between the BMI and FBG with r=0.217, p=0.008; and between the WHR and FBG with r=0.21, p=0.01 amongst all students. In this study, male students have significantly higher BMI and WHR than females. Higher FBG was well observed in students with either higher BMI or WHR.

THE COMPARISON OF CIGARETTE CONSUMPTION TOWARDS SEMEN ANALYSIS IN ANDROLOGY POLYCLINIC OF DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA IN 2017 Yohanes Widyakusuma Eka Saputra; Kristanti Wanito Wigati; Rina Yudiwati; Ni Wajan Tirthaningsih
Majalah Biomorfologi Vol. 31 No. 2 (2021): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v31i2.2021.31-38

Background: The habit of smoking tobacco is a lifestyle that has become a necessity for some people. Sometimes, social needs is the main reason for someone to have a smoking habit. Based on this problem, the level of cigarette consumption in the community has increased. Nowadays, the total number of couples visiting an infertility clinic is on the rise. This have led to an assumption among the community that smoking tobacco is one of the main factors causing male infertility. Objective: to compare light smokers and heavy smokers towards the results of semen analysis in infertile male patients. Materials and Methods: This study was an observational analytics, with a retrospective-cross sectional. The instrument used in this study was taken from medical records of the patients who visited the Andrology Clinic of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, for the period from January to December 2017. The observed semen analysis parameters were concentration, motility, and morphology for microscopic examination and liquefaction, pH, and volume for macroscopic examination, by following the inclusion and exclusion criteria. Results: Ninety-two samples of infertile male participants (50 light smokers and 42 heavy smokers) were included in this study. Semen analysis on its concentration, motility, spermatozoa morphology, as well as liquefaction, pH, and volume) towards the number of cigarette consumption showed no significant difference (p>0.05) between light smokers and moderate smokers. Conclusion: There was no significant difference between the light smoker and heavy smoker groups on the results of the semen analysis.

VITAMIN C PREVENTS STRESS INDUCED CARDIOMYOPATHY IN PRENATAL NOISE EXPOSED RODENTS Winnie Nirmala Santosa; Viskasari P. Kalajanti; Ni Wajan Tirthaningsih
Buletin Farmatera Vol 4, No 2 (2019)
Publisher : Universitas Muhammadiyah Sumatera Utara

Potency of oral vitamin C to prevent cardiomyopathy in prenatal noise exposed newborn Wistar rats was studied by comparing the cardiomyocyte numbers and the extracellular matrix expressions (ECM) to controls. Twenty-four newborns (NR) of 32 pregnant mothers were divided equally into 4 groups: K1 (distilled water [DW]), K2 (150 mg/kg of BW oral vitamin C once daily [VC]), P1 (4 hours daily of white noise at 95 dB [WN]+DW), and P2 (WN+VC). VC and WN were given from D1 till birth and from D15 till birth, respectively. The hearts of NR were harvested, and processed for histology slides (2 midsagittal 4 μ cut slides/ animal) stained with hematoxyllin-eosin and Masson trichrome for the cardiomyocytes and ECM quantification at the ventricles using Image Raster 3.0 and ImageJ, respectively. Pictures from 8 visual fields/ slide were taken and analyzed in duplicate (400x magnifications under a light microscope). Data were analyzed using SPSS 17; significance level of p<0.05. In P1, the cardiomyocite cell numbers was significantly lowest (p<0.001); whilst the ECM was significantly highest than K1, K2, P2 (p<0.001 and p<0.005, respectively). Here, vitamin C could prevent the adverse effect of prenatal noise exposures in the ventricle myocardium of newborn rats.Keywords: cardiomyopathy, hypertrophy, prenatal noise, vitamin C

PENGARUH SEKAT ALUMINIUM FOIL TERHADAP RASIO NEURON DAN NEUROGLIA JARINGAN SEREBRI TIKUS WISTAR JANTAN YANG DIBERI PAPARAN RADIASI ELEKTROMAGNETIK Irmawan Farindra; Warda Elmaida Rusdi; Viskasari P Kalanjati; Ni Wajan Tirthaningsih
Biomedika Vol 14, No 2 (2022): Biomedika Agustus 2022
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v14i2.18725

ABSTRAK Telepon selular merupakan salah satu sumber radiasi elektromagnetik (EMR). Peningkatan penggunaan telepon selular dapat meningkatkan efek negatif EMR sebagai salah satu penyebab stres oksidatif pada tubuh manusia diantaranya jaringan serebri. Aluminium foil (AF) adalah salah satu bahan yang direkomendasikan untuk melindungi otak dari efek negatif EMR karena memiliki potensi absorption loss and reflective loss. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian sekat AF terhadap EMR dari telepon selular terhadap rasio neuron dan neuroglia pada jaringan serebri tikus Wistar jantan dewasa. Sebanyak 32 ekor tikus jantan dewasa dibagi menjadi 4 kelompok (n=8). Kelompok KI EMR (-) dan AF (-); Kelompok K2 EMR (-) dan AF (+); Kelompok P1 EMR (+) dan AF (-); Kelompok P2 EMR (+) dan AF (+). Telepon selular (GSM 2100 MHz; SAR 0,84-1,86 W/kg) diletakkan di dasar wadah kotak plastik , kemudian dipaparkan 4 jam/ hari selama 30 hari. Data jumlah neuron dan neuroglia tiap kelompok dianalisis dengan tingkat signifikansi p0,05 (uji one way ANOVA, SPSS 17). Dari hasil rasio neuron dan neuroglia didapatkan penurunan rasio pada kelompok perlakuan dibandingkan kontrol, serta peningkatan rasio pada kelompok perlakuan P2 dibandingkan kelompok P1. Hal tersebut membuktikan AF dapat melindungi dari efek negatif EMR dengan meningkatkan jumlah neuroglia sebagai respon proteksi terhadap kerusakan neuron pada jaringan serebri.Kata Kunci: Aluminium Foil, Radiasi Elektromagnetik, Telepon Seluler; Serebri, Neuron, Neuroglia ABSTRACT Cellular phones are a source of electromagnetic radiation (EMR). Increased use of cellular phones, can increase the negative effects of EMR as one of the causes of oxidative stress in the human body, including cerebral tissue. Aluminum foil (AF) is one of the recommended materials as protection against the negative effects of EMR because it has the potential for absorption loss and reflective loss. This study aims to determine the effect of AF blocking on EMR from cellular phones, where the variables studied were the number of neurons and neuroglia, as well as the ratio of neurons and neuroglia in the cerebral tissue of adult male Wistar rats. This study used 32 adult male rats which were divided into 4 groups (n=8). Each mouse was placed in a plastic box container measuring 20x16x9 cm with a wire cover. A cellular phone (GSM 2100 MHz; SAR 0.84-1.86 W/kg) was placed at the bottom of the plastic case and exposed 4 hours/day for 30 days. Data were analyzed with a significance level of p0.05 (Kruskal-Wallis test or ANOVA, SPSS 17). From these results, it is evident that AF can protect against the negative effects of EMR by reducing the effects of oxidative stress by reducing neuronal damage in cerebral tissue.Keywords: Aluminium Foil, Electromagnetic Radiation, Mobile Phone, Brain, Neuron, Neuroglia

Body Mass Index and Urinalysis Markers in the Seemingly Healthy Young Adults Pradana, Krisnawan Andy; Kalanjati, Viskasari P; Tirthaningsih, Ni Wajan
Folia Medica Indonesiana Vol. 56 No. 2 (2020): June
Publisher : Universitas Airlangga

Higher prevalence of albuminuria, glycosuria, and haematuria was reported in the obese people than control. We aimed to analyze the BMI and urinalysis markers among the university students aged 18-21 years old in the IIKBW, Kediri to study any correlations and differences between these variables, which to the best of our knowledge has yet widely reported in Indonesia. This study has ethics approval from Universitas Airlangga, Surabaya. The BMI was analyzed from the body weight and height of male (n=74) and female (n=76) students with no health problems recorded. The pH, nitrites, protein, erythrocytes, glucose in the urine were measured qualitatively with a dip-stick method, blinded, using the midstream urine sample collected in the morning. Data were analyzed using SPSS 17, with a level of significance of p<0.05. Abnormal pH (n=75), positive nitrites (n=24), haematuria (n=6), and proteinuria (n=149) were recorded. About 22% of students suffered from type I obesity, and 8.7% of type II. Males were significantly suffered from the obesity whilst females from the overweight (p<0.05). No significant correlations between the BMI and each urinalysis marker (BMI and nitrites p=0.936; BMI and protein p=1; BMI and pH p=0.835; BMI and blood, p=0.486; respectively); no one were found with glycosuria. No significant differences either on the BMI or the 5 urinalysis markers between male and female groups (p>0.05). Whilst no positive glycosuria samples were identified; 18.9% of males and 13.2% of females have positive nitrites, 100% of males and 98.7% of females have positive proteinuria, 2.7% of males and 7.9% of females have positive haematuria. There were 7.33% of males and 6% of females having an increased pH; whilst 20.66% of males and 16% of females having a decreased pH. Amongst the seemingly healthy university students, we found cases of urinalysis marker impairment, although no significant correlations on the BMI to the urinalysis markers that may be representing early detection for renal diseases were observed.

Profile of Colorectal Tumor in Gastroentero-Hepatology Center, Department of Internal Medicine, Dr Soetomo Hospital, Surabaya Thamrin, Husin; Ilmiah, Khafidhotul; Tirthaningsih, Ni Wajan
Folia Medica Indonesiana Vol. 56 No. 1 (2020): March
Publisher : Universitas Airlangga

Colorectal cancer has became burden in the world.The latest study shows that colorectal cancer is the third most common cancer in men and second most common cancer in women globally. There are difference characteristic of epidemiology in every countries. Moreover, there is no study that represents epidemiology of colorectal cancer in Indonesia yet, especially in East Java. The aim of this study was to describe colorectal tumor profile by age and gender in Gastroentero-Hepatology Center, Dr Soetomo Hospital. This study has received a certificate of Ethical Clearance No.273/Panke.KKE/IV/2015, a descriptive retrospective study. We collected data using medical records, and patients who have been colonoscopy examination and suspected colorectal tumor were included. There were 201 patients, divided to 100 males and 101 females. The peak of incidence was on 51-60 years old group, but on the 31-40 years old incidence of colorectal tumor was increased. The youngest patient was 17 years old. And tumors are more likely develop in distal area, especially in rectum. This study shows a different characteristic profile of colorectal tumor, where tumor is developed at young people and there is no significant difference between male and female for the incidence.

Profil Pasien Infeksi Saluran Kemih Pada Anak di Puskesmas Surabaya Periode Januari-Desember 2018 Dewi, Maharani Sita; Prasetyo, Risky Vitria; Tirthaningsih, Ni Wajan; Puspitasari, Dwiyanti
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 9, No 1 (2021): EDITION MARCH 2021
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v9i1.1962

Infeksi Saluran Kemih merupakan salah satu penyakit yang sering terjadi pada anak. Gejala infeksi saluran kemih bervariasi tergantung dengan usia dan jenis kelamin. Sering kali infeksi saluran kemih terjadi pada perempuan daripada laki-laki. Penelitian ini menggunakan metode retrospektif potong lintang. Data yang diambil yaitu rekam medik pasien di Puskesmas Surabaya dengan teknik pengumpulan data cluster random sampling. Hasil penelitian ini menunjukkan bahwa pasien anak yang mengalami infeksi saluran kemih di Puskesmas Surabaya dengan usia 1-6 tahun (34,8%), jenis kelamin perempuan dan laki-laki (50%), dengan keluhan buang air kecil nyeri (86%), dari hasil urinalisis didapatkan bakteriuria. Pasien anak yang mengalami infeksi saluran kemih dari tipe pembiayaan menggunakan Badan Penyelenggara Jaminan Sosial-Penerima Bantuan Iuran (60,9%) di Puskesmas Jeruk (41,3%). Pasien infeksi saluran kemih pada penelitian ini yang berjenis kelamin laki-laki maupun perempuan memiliki nilai yang sama, berusia 1-6 tahun, dengan keluhan buang air kecil nyeri. Lokasi puskesmas yang terdapat banyak pasien infeksi saluran kemih pada anak ialah Puskesmas Jeruk dengan tipe pembiayaan Badan Penyelenggara Jaminan Sosial - Penerima Bantuan Iuran. Kata kunci: Anak, infeksi saluran kemih, puskesmas

Co-Authors Andarisa Rachman Nugraha Ashon Sa’adi Dewi, Maharani Sita Dwiyanti Puspitasari, Dwiyanti Hidayaturrahmi, Hidayaturrahmi Ilmiah, Khafidhotul Irmawan Farindra Joni Wahyuhadi, Joni Maria Inge Lusida Oktariza, Rury Tiara Olivia Setiawan Pradana, Krisnawan Andy R. Yuvasanghar Ravindra Mohan RINA YUDIWATI BM, RINA Risky Vitria Prasetyo Thamrin, Husin Viskasari P. Kalanjati Warda Elmaida Rusdi Wigati, Kristanti Wanito Winnie Nirmala Santosa Yohanes Widyakusuma Eka Saputra

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