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All Journal E-Jurnal Medika Udayana Indonesian Journal of Urology Health Notions JBN (Jurnal Bedah Nasional) Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Indian Journal of Forensic Medicine & Toxicology Narra J Folia Medica Indonesiana
wahjoe djatisoesanto
Department Of Urology, Faculty Of Medicine, Universitas Airlangga, Dr Soetomo Hospital, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Narra J

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Comparison of efficacy and safety of open and laparoscopic proximal ureterolithotomy for ureteral stone management: A systematic review and meta-analysis Maliki, Ahmad; Fitriani, Rizka; Soebadi, Mohammad A.; Djatisoesanto, Wahjoe
Narra J Vol. 4 No. 1 (2024): April 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i1.679

Abstract

Despite advances in non-invasive and minimally invasive techniques, some proximal ureteral stones with impaction require open or laparoscopic surgery. No systematic reviews or meta-analyses have compared the efficacy and safety of open proximal ureterolithotomy and laparoscopic approaches. The aim of this study was to compare the efficacy and safety between open and laparoscopic proximal ureterolithotomy for ureteral stone management. Following the PRISMA guidelines, systematic searches were conducted in five databases (PubMed, Scopus, ScienceDirect, Web of Science, and ProQuest) to identify articles comparing those two surgical approaches. Operative time, blood loss, pain score, hospital stay, recovery time, and complications were collected and compared. Heterogeneity-based meta-analysis with random-effects or fixed-effects models were conducted. Two randomized controlled trials and four observational cohort studies with 386 participants met the criteria. Open surgery had significantly less time than laparoscopic ureterolithotomy (mean difference (MD): 26.63 minutes, 95%CI: 14.32, 38.94; p<0.0001). Intraoperative blood loss (MD: -1.27 ml; 95%CI: -6.64, 4.09; p=0.64) and overall complications (OR: 0.68; 95%CI: 0.41, 1.15; p=0.16) were not significantly different between two approaches. Laparoscopic ureterolithotomy reduced visual analogue scale (VAS) pain scores (MD: -2.53; 95%CI: -3.47, -2.03; p<0.00001), hospital stays (MD: -2.40 days; 95%CI: -3.42 to -1.38 days; p=0.03), and recovery time (MD: -9.67 days; 95%CI: -10.81 to -8.53 days; p<0.00001). In conclusion, open proximal ureterolithotomy had less time, but laparoscopic surgery reduced postoperative pain, hospital stay, and recovery time. Both methods had comparable intraoperative bleeding and complications.
Diagnostic accuracy of urinary cytokeratin fragment-19 (CYFRA21-1) for bladder cancer Setianingsih, Yennie A.; Djatisoesanto, Wahjoe; Laksita, Tetuka B.; Aryati, Aryati
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.1142

Abstract

Bladder cancer is known for its high recurrence rate and requires constant patient monitoring. To confirm the diagnosis, a tissue sample from a cystoscopy is required, which the patient often avoids. Urine has the potential to be utilized as a diagnostic fluid because of its non-invasive nature and various biomarker contents. The aim of this study was to determine the diagnostic value of cytokeratin fragment-19 (CYFRA21-1) level in urine for diagnosing bladder cancer. This single-center cross-sectional study was performed with eligible inclusion were adults aged ≥18 years who presented with hematuria and suspected bladder cancer from imaging. Patients with a history of intravesical chemotherapy, radiotherapy and immunotherapy were excluded. Urine samples were collected prior to the cystoscopy. Detection of urinary CYFRA21-1 was carried out using the ELISA method. Of 154 patients included in the study, the diagnosis of bladder cancer was confirmed in 92 patients. Patients with bladder cancer had significantly higher urinary CYFRA21-1 levels compared to the non-bladder cancer group. The sensitivity, specificity, positive and negative predictive value, and positive likelihood ratio of the CYFRA21-1 were 80.4%, 43.5%, 67.9%, 60% and 1.425, respectively. The area under the curve for CYFRA21-1 was 0.608, computed from a receiver operating curve with a cut-off value of 13.3 ng/mL. In conclusion, urinary CYFRA21-1 levels have moderate diagnostic accuracy in determining bladder cancer among suspected individuals. Due to its high sensitivity, this biomarker could potentially be used alongside other screening tools for bladder cancer detection.
Co-Authors A.A. Ketut Agung Cahyawan W Abdul Azis Affandi, Yohan Affandi, Yohan Ahmad Kholis Anton Hermawan Arif Rachman Arif Rananda Aryati Aryati Castiglione, Fabio Diansyah, Ramzie Nendra Doddy M Soebadi Doddy M. Soebadi Doddy M. Soebadi Doddy M. Soebadi Dyah Erawati, Dyah DYAH FAUZIAH, DYAH Endang Retnowati Febriansyah, Nafis Audrey Ferdiansyah Mahyudin Firmantya Hadi Pranata Furqan Hidayatullah HASAN MADANI Hoesain, Fadil Pramudhya Holyness Nurdin Singadimedja I'tishom, Reny Ida Bagus Putra Pramana Indra Bachtiar Indri Lakhsmi Putri, Indri Lakhsmi Johan Renaldo Kristian Yoci Santoso Yoci Santoso Laksita, Tetuka B. Lukman Hakim Lukman Hakim Lukman Hakim M. Asro Abdih Mahrany Graciella Bumbungan maliki, ahmad Mawdudi, Ari Alauddin Muhammad Fawzi Zulfikar Muhammad Husni Tamrin Mukti, Ade Indra Nindra Prasadja Nugroho, Achmad Nugroho, Ahmad Nurakbariansyah, Rocky Pranata, Firmantya Hadi Rezia, Dian Kartika Rizaldi, Fikri Rizka Fitriani Sabilal Alif Sawal, Zuhri Sawal, Zuhri Setianingsih, Yennie A. Sirait, Binsar Marshall Maranatha Soebadi, Doddy Moesbadianto Soebadi, Mohammad A. Soetojo Soetojo Sunaryo Hardjowijoto Tamrin, Muhammad Husni Tarmono Djojodimedjo Tri Wulanhandarini Wicaksono, Dillon Martino Widodo J Pudjirahardjo Widodo J Pujiraharjo Wijayanto, Cahyo Zulfian Hasibuan Zulfikar, Muhammad Fawzi