Article Per Year (5 Year)
p-Index From 2021 - 2026
0.817
P-Index
This Author published in this journals
All Journal Buletin Ekonomi Perikanan Proceedings of Annual International Conference Syiah Kuala University - Social Sciences Chapter Jurnal Unik: Pendidikan Luar Biasa Jurnal Kartika Kimia FITOFARMAKA: Jurnal Ilmiah Farmasi Jurnal Farmasi Indonesia Jurnal Riset Sains dan Kimia Terapan Jurnal Kesehatan Rajawali Metalurgi
Nani Suryani
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 11 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 11 Documents
Search

 1   2 
Standardisasi Ekstrak Khaya (Khaya anthotheca) Sebagai Antikanker Payudara MCF-7 (Michigan Cancer Foundation-7) Parwaz Setaviani; Nani Suryani; Zahra Khaerul Kamila; Siti Amaliya; Eneng Elda Ernawati; Tarso Rudiana; Arini Khaerunnisa
Jurnal Farmasi Indonesia Vol 21 No 2 (2024): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v21i2.2475

Abstract

Cancer is the second non-communicable disease that causes the largest number of deaths after cardiovascular disease. The chemical compounds contained in the Khaya anthotheca plant and which have anticancer activity include methyl angolensate, 7-deacetylhivorin, grandifolione, gedunin, , obacunone and Cathecin. This research aims to determine the standardization of extracts and determine anticancer activity against MCF-7 breast cancer cells. The method used in this research is standardization of specific and non-specific parameters, and cytotoxic testing using Prestoblue. The results of extract standardization of specific parameters have values ​​for soluble essence in water and ethanol of 4.68% and 5.80% (meeting the requirements). Non-specific parameters drying loss 0.739%, ash content 8.02%, microbial contamination 0 colonies, lead (Pb) 0.2976 mg/kg, cadmium (Cd) ≤0.001 mg/kg (qualified) and IC₅₀ value of anticancer activity breast MCF-7 from Khaya anthoteca extract was 194.20 µg/mL in the medium/moderate category
Co-Authors Alfi Mahmudah Arini Khaerunnisa Basril Abbas Devi Nurjanah Dimas Danang Indriatmoko Dodik Efendi Dwi Putri Lestari Eneng Elda Ernawati Hendrawati Hendrawati Isalmi Aziz M. Ikhsan Marwan Marwan Mila Kurniah Parwaz Setaviani Saiman . Siti Amaliya Tarso Rudiana Tarso Rudiana, Tarso Yessy Warastuti Zahra Khaerul Kamila